TERF1 (telomeric repeat binding factor 1) - Rat Genome Database

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Gene: TERF1 (telomeric repeat binding factor 1) Canis lupus familiaris
Analyze
Symbol: TERF1
Name: telomeric repeat binding factor 1
RGD ID: 12177641
Description: ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN meiotic telomere clustering (ortholog); negative regulation of exonuclease activity (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH breast cancer (ortholog); squamous cell carcinoma (ortholog); stomach cancer (ortholog); FOUND IN spindle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: telomeric repeat-binding factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,664,378 - 21,701,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2921,773,883 - 21,811,414 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TERF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,664,378 - 21,701,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2921,773,883 - 21,811,414 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBIUU_Cfam_GSD_1.0
TERF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38873,008,864 - 73,048,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl873,008,856 - 73,048,123 (+)EnsemblGRCh38hg38GRCh38
GRCh37873,921,099 - 73,960,358 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36874,083,661 - 74,122,281 (+)NCBINCBI36Build 36hg18NCBI36
Build 34874,083,662 - 74,122,281NCBI
Celera869,918,262 - 69,957,163 (+)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef869,411,980 - 69,450,876 (+)NCBIHuRef
CHM1_1873,973,943 - 74,012,842 (+)NCBICHM1_1
T2T-CHM13v2.0873,437,901 - 73,477,172 (+)NCBIT2T-CHM13v2.0
Terf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,875,634 - 15,914,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,875,870 - 15,914,276 (+)EnsemblGRCm39 Ensembl
GRCm38115,805,546 - 15,844,052 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,805,646 - 15,844,052 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,795,739 - 15,833,510 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,790,872 - 15,828,643 (+)NCBIMGSCv36mm8
Celera115,750,793 - 15,788,563 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.88NCBI
Terf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr858,226,345 - 8,255,614 (-)NCBIGRCr8
mRatBN7.253,443,103 - 3,472,377 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl53,443,106 - 3,472,340 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx55,560,595 - 5,589,792 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.057,199,479 - 7,228,676 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.056,896,804 - 6,926,212 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,853,455 - 2,882,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl52,853,459 - 2,882,668 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.052,843,150 - 2,872,418 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.452,556,918 - 2,586,086 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.152,556,917 - 2,586,086 (-)NCBI
Celera53,039,138 - 3,068,345 (-)NCBICelera
Cytogenetic Map5q11NCBI
Terf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554447,103,552 - 7,150,323 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554447,103,282 - 7,149,450 (-)NCBIChiLan1.0ChiLan1.0
TERF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2788,753,525 - 88,792,513 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1864,383,202 - 64,422,226 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0869,545,115 - 69,583,997 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1871,192,716 - 71,231,648 (+)NCBIpanpan1.1PanPan1.1panPan2
Terf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530357,612,694 - 57,639,199 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366481,809,395 - 1,835,890 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TERF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl462,797,000 - 62,831,454 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1462,797,244 - 62,831,459 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2468,341,702 - 68,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TERF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1868,608,830 - 68,647,220 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl868,608,844 - 68,648,171 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603972,734,995 - 72,774,562 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Terf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474418,121,687 - 18,156,989 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474418,120,677 - 18,156,920 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TERF1
423 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005638041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005638042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022412325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038515960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038515961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038579519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038579520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038643772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000012746   ⟹   ENSCAFP00000011804
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000046114   ⟹   ENSCAFP00000040715
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845049253   ⟹   ENSCAFP00845038653
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2921,773,883 - 21,811,414 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845049301   ⟹   ENSCAFP00845038690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2921,773,883 - 21,811,414 (+)Ensembl
RefSeq Acc Id: XM_005638041   ⟹   XP_005638098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,379 - 21,700,880 (+)NCBI
Dog10K_Boxer_Tasha2921,929,298 - 21,966,341 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005638042   ⟹   XP_005638099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,378 - 21,701,491 (+)NCBI
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038441382   ⟹   XP_038297310
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02921,773,862 - 21,811,415 (+)NCBI
RefSeq Acc Id: XM_038441383   ⟹   XP_038297311
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBI
RefSeq Acc Id: XM_038515960   ⟹   XP_038371888
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12921,832,465 - 21,869,553 (+)NCBI
RefSeq Acc Id: XM_038515961   ⟹   XP_038371889
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBI
RefSeq Acc Id: XM_038579519   ⟹   XP_038435447
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02922,149,878 - 22,187,001 (+)NCBI
RefSeq Acc Id: XM_038579520   ⟹   XP_038435448
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBI
RefSeq Acc Id: XM_038643771   ⟹   XP_038499699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02921,868,612 - 21,906,117 (+)NCBI
RefSeq Acc Id: XM_038643772   ⟹   XP_038499700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBI
RefSeq Acc Id: XP_005638099   ⟸   XM_005638042
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005638098   ⟸   XM_005638041
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MMG4 (UniProtKB/TrEMBL),   A0A8C0KZF6 (UniProtKB/TrEMBL),   A0A8I3PZA1 (UniProtKB/TrEMBL),   A0A8C0TRX8 (UniProtKB/TrEMBL),   A0A8I3QA83 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000011804   ⟸   ENSCAFT00000012746
Ensembl Acc Id: ENSCAFP00000040715   ⟸   ENSCAFT00000046114
RefSeq Acc Id: XP_038371889   ⟸   XM_038515961
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038371888   ⟸   XM_038515960
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038499700   ⟸   XM_038643772
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038499699   ⟸   XM_038643771
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038297311   ⟸   XM_038441383
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038297310   ⟸   XM_038441382
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MMG4 (UniProtKB/TrEMBL),   A0A8C0KZF6 (UniProtKB/TrEMBL),   A0A8I3PZA1 (UniProtKB/TrEMBL),   A0A8C0TRX8 (UniProtKB/TrEMBL),   A0A8I3QA83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038435448   ⟸   XM_038579520
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038435447   ⟸   XM_038579519
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KZF6 (UniProtKB/TrEMBL),   A0A8C0MMG4 (UniProtKB/TrEMBL),   A0A8C0TRX8 (UniProtKB/TrEMBL),   A0A8I3PZA1 (UniProtKB/TrEMBL),   A0A8I3QA83 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038690   ⟸   ENSCAFT00845049301
Ensembl Acc Id: ENSCAFP00845038653   ⟸   ENSCAFT00845049253
Protein Domains
HTH myb-type   Myb-like

Promoters
RGD ID:13688424
Promoter ID:EPDNEW_C6492
Type:multiple initiation site
Name:TERF1_1
Description:telomeric repeat binding factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12921,664,397 - 21,664,457EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007975 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030007223 UniProtKB/TrEMBL
  ENSCAFG00040024239 UniProtKB/TrEMBL
  ENSCAFG00845027899 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012746.5 UniProtKB/TrEMBL
  ENSCAFT00000046114.4 UniProtKB/TrEMBL
  ENSCAFT00030013252.1 UniProtKB/TrEMBL
  ENSCAFT00030013374.1 UniProtKB/TrEMBL
  ENSCAFT00040045185.1 UniProtKB/TrEMBL
  ENSCAFT00040045215.1 UniProtKB/TrEMBL
  ENSCAFT00845049253 ENTREZGENE
  ENSCAFT00845049253.1 UniProtKB/TrEMBL
  ENSCAFT00845049301.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.210 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Myb_dom UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  Telomere_rpt-bd_fac_dimer_dom UniProtKB/TrEMBL
  Telomere_rpt-bd_fac_dimer_sf UniProtKB/TrEMBL
  TERF1/2 UniProtKB/TrEMBL
  TRBD-Containing_Protein UniProtKB/TrEMBL
KEGG Report cfa:100684790 UniProtKB/TrEMBL
NCBI Gene TERF1 ENTREZGENE
PANTHER TELOMERIC REPEAT-BINDING FACTOR 1 UniProtKB/TrEMBL
  TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 UniProtKB/TrEMBL
Pfam Myb_DNA-binding UniProtKB/TrEMBL
  TRF UniProtKB/TrEMBL
PIRSF Telomere_bd-1_Pin2 UniProtKB/TrEMBL
PROSITE HTH_MYB UniProtKB/TrEMBL
  MYB_LIKE UniProtKB/TrEMBL
SMART SANT UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF63600 UniProtKB/TrEMBL
UniProt A0A8C0KZF6 ENTREZGENE
  A0A8C0MMG4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TRX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PZA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QA83 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47254 ENTREZGENE