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Gene: ATP6V1E2 (ATPase H+ transporting V1 subunit E2) Canis lupus familiaris

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Symbol:

ATP6V1E2

Name:

ATPase H+ transporting V1 subunit E2

RGD ID:

12177191

Description:

ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN proton transmembrane transport (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); FOUND IN acrosomal vesicle (inferred); proton-transporting two-sector ATPase complex, catalytic domain (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

V-type proton ATPase subunit E 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	48,746,331 - 48,754,047 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	48,600,601 - 48,609,203 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	49,617,392 - 49,625,990 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	49,617,575 - 49,618,255 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	49,325,448 - 49,334,035 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	49,615,682 - 49,624,276 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	49,798,781 - 49,807,379 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Lynch syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

monoatomic ion transport (IEA)

proton transmembrane transport (IEA,ISO)

Cellular Component

acrosomal vesicle (IEA)

proton-transporting two-sector ATPase complex, catalytic domain (IEA)

Molecular Function

protein binding (ISO)

proton-transporting ATPase activity, rotational mechanism (IBA,IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ATP6V1E2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	48,746,331 - 48,754,047 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	48,600,601 - 48,609,203 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	49,617,392 - 49,625,990 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	49,617,575 - 49,618,255 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	49,325,448 - 49,334,035 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	49,615,682 - 49,624,276 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	49,798,781 - 49,807,379 (-)	NCBI		UU_Cfam_GSD_1.0

ATP6V1E2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	46,511,847 - 46,542,577 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	46,490,750 - 46,542,577 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	46,738,986 - 46,769,716 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	46,592,490 - 46,600,600 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	46,650,638 - 46,658,747	NCBI
Celera	2	46,577,658 - 46,585,772 (-)	NCBI		Celera
Cytogenetic Map	2	p21	NCBI
HuRef	2	46,476,563 - 46,484,674 (-)	NCBI		HuRef
CHM1_1	2	46,669,331 - 46,677,438 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	46,516,901 - 46,547,610 (-)	NCBI		T2T-CHM13v2.0

Atp6v1e2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	87,251,537 - 87,255,315 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	87,251,537 - 87,255,325 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	86,944,109 - 86,947,887 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	86,944,109 - 86,947,897 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	87,343,449 - 87,347,227 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	86,852,435 - 86,856,213 (-)	NCBI		MGSCv36	mm8
Celera	17	91,322,839 - 91,326,611 (-)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI
cM Map	17	56.9	NCBI

Atp6v1e2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	13,417,046 - 13,425,628 (+)	NCBI		GRCr8
mRatBN7.2	6	7,667,359 - 7,673,711 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	7,667,564 - 7,672,626 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	7,946,740 - 7,950,655 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	8,256,150 - 8,260,065 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	7,783,275 - 7,787,190 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	10,510,370 - 10,517,059 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	10,511,452 - 10,515,370 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	20,499,969 - 20,508,542 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	10,391,729 - 10,395,647 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	10,391,879 - 10,396,115 (-)	NCBI
Celera	6	7,403,594 - 7,407,511 (+)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

Atp6v1e2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	13,432,951 - 13,458,467 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955441	13,432,951 - 13,458,467 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATP6V1E2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	79,847,862 - 79,878,241 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	79,851,830 - 79,882,206 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	46,627,574 - 46,658,180 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	47,558,819 - 47,589,194 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	47,559,015 - 47,559,695 (-)	Ensembl	panpan1.1		panPan2

Atp6v1e2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	34,317,614 - 34,322,869 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936508	5,750,595 - 5,751,275 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP6V1E2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	94,032,773 - 94,033,453 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	94,012,252 - 94,078,475 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	100,097,229 - 100,118,012 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP6V1E2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	60,648,934 - 60,895,703 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	60,695,500 - 60,696,180 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	51,157,782 - 51,197,117 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp6v1e2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624738	27,975,166 - 27,980,969 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ATP6V1E2
78 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038489204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038615105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038680489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_538480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00845049158 ⟹ ENSCAFP00845038571

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	10	49,617,575 - 49,618,255 (-)	Ensembl

RefSeq Acc Id:

XM_038489204 ⟹ XP_038345132

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	10	49,325,448 - 49,334,035 (-)	NCBI

RefSeq Acc Id:

XM_038551206 ⟹ XP_038407134

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	10	49,798,781 - 49,807,379 (-)	NCBI

RefSeq Acc Id:

XM_038615105 ⟹ XP_038471033

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	10	49,615,682 - 49,624,276 (-)	NCBI

RefSeq Acc Id:

XM_038680489 ⟹ XP_038536417

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	10	49,617,392 - 49,625,990 (-)	NCBI

RefSeq Acc Id:

XM_538480 ⟹ XP_538480

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	10	48,746,331 - 48,754,047 (-)	NCBI
Dog10K_Boxer_Tasha	10	48,600,601 - 48,609,203 (-)	NCBI

Sequence:

show sequence

ATTCAAGTCTCAGGGTCTGGCTGTGAGGGTCTTCTGCAGAGAGAAGGAGGCAACAGTGCCAGGT
TCCAGCGTGCCTTCCAAGTTCCACATTCCGTGCGCAGACTCCCGGCGCCAGAGCGAAGGCCGGC
CCTTGGCAGGACACCGGCTGAGGAAGTGGCATTCTGAAGTCATTCCTGAAATTCTGCCCTAAAT
CAAAGGAGCCAGAGGGCCCGCGAATTCTCCCTCTACCTCCCTTTCCAGGAGCAACCATGGCCCT
AAGTGATGGCGATGTACAGAAGCAGATTAAGCACATGATGGCTTTCATTGAACAGGAAGCCAAT
GAAAAGGCAGAAGAAATAGATGCCAAGTCTGAGGAAGAGTTCAATATTGAGAAAGGACGCCTTG
TGCAAACCCAACGACTAAAGATTATGGAGTATTATGAGAAGAAGGAGAAGCAAATAGAGCAGCA
GAAGAAAATCCAGATGTCCACCATGAGGAATCAGGCAAGGCTGAAAGTCCTAAGAGCCCGAGAT
GACCTCATCTCAGAGTTGCTGAATGATGCAAAGCTGAGACTCAGCAGGATTGTGGCCGACCCAG
AAGTCTACCAGGGGCTCCTGGATAAACTAGTGCTCCAGGGTCTGCTCCGGCTGCTGGAGCCCGT
GGTAATTATACGCTGCAGGCCACAGGACCTCCTCCTGGTGGAGGCTGCAGTGCTAAAAGCCATC
CCTGAGTACATGGCAGTCTCCCATAAATGTGTGGAAGTCCAAGTTGATCAAGAGGTGCACCTGT
CTATGAATGCAGCTGGAGGTGTGGAGGTCTACAGTGGCAATCAGAGAATAAAGGTTTCCAATAC
CCTAGAAAGTCGACTGGATCTCTTAGCCCAACAAAAGATGCCTGAAATACGAAAGGCCTTGTTT
GGAGCCAATGCCAACAGAAAGTTCTTTATATAAGCCTCTGTGAAGTGAAGCTCATGTTGAATTG
CTAAGCCATTAAAAGCCTAAGTTATTAGGGCAAAGGAAACTAGTAATGTTTCCTCCTCTTTGTT
GTTTTCACAGGAGTCTATTATCTTTCATGAAGTGCCCTCTGAATAGCTAAAAGCGTATTTTGGA
ATAAAACCTGAAAATGCTTATAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038345132	(Get FASTA)	NCBI Sequence Viewer
	XP_038407134	(Get FASTA)	NCBI Sequence Viewer
	XP_038471033	(Get FASTA)	NCBI Sequence Viewer
	XP_038536417	(Get FASTA)	NCBI Sequence Viewer
	XP_538480	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000071759.1
	ENSCAFP00030017839.1
	ENSCAFP00040014856.1
	ENSCAFP00845038571
	ENSCAFP00845038571.1

RefSeq Acc Id:

XP_538480 ⟸ XM_538480

- UniProtKB:

A0A8C0LRH4 (UniProtKB/TrEMBL), A0A8C0RHM0 (UniProtKB/TrEMBL), A0A8P0PN00 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALSDGDVQKQIKHMMAFIEQEANEKAEEIDAKSEEEFNIEKGRLVQTQRLKIMEYYEKKEKQI
EQQKKIQMSTMRNQARLKVLRARDDLISELLNDAKLRLSRIVADPEVYQGLLDKLVLQGLLRLL
EPVVIIRCRPQDLLLVEAAVLKAIPEYMAVSHKCVEVQVDQEVHLSMNAAGGVEVYSGNQRIKV
SNTLESRLDLLAQQKMPEIRKALFGANANRKFFI

hide sequence

RefSeq Acc Id:

XP_038345132 ⟸ XM_038489204

RefSeq Acc Id:

XP_038471033 ⟸ XM_038615105

RefSeq Acc Id:	XP_038536417 ⟸ XM_038680489
- UniProtKB:	A0A8C0S2C4 (UniProtKB/TrEMBL), A0A8I3PYI5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038407134 ⟸ XM_038551206
- UniProtKB:	A0A8C0S2C4 (UniProtKB/TrEMBL), A0A8I3PYI5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845038571 ⟸ ENSCAFT00845049158

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000054145	UniProtKB/TrEMBL
	ENSCAFG00030011043	UniProtKB/TrEMBL
	ENSCAFG00040009257	UniProtKB/TrEMBL
	ENSCAFG00845027863	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000097649.1	UniProtKB/TrEMBL
	ENSCAFT00030020447.1	UniProtKB/TrEMBL
	ENSCAFT00040017141.1	UniProtKB/TrEMBL
	ENSCAFT00845049158	ENTREZGENE
	ENSCAFT00845049158.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.2320.30	UniProtKB/TrEMBL
	6.10.250.1620	UniProtKB/TrEMBL
InterPro	ATPase_E_C	UniProtKB/TrEMBL
	ATPase_V1_Esu	UniProtKB/TrEMBL
KEGG Report	cfa:481359	UniProtKB/TrEMBL
NCBI Gene	ATP6V1E2	ENTREZGENE
PANTHER	PTHR45715	UniProtKB/TrEMBL
	V-TYPE PROTON ATPASE SUBUNIT E 2	UniProtKB/TrEMBL
Pfam	vATP-synt_E	UniProtKB/TrEMBL
Superfamily-SCOP	V-type ATPase subunit E-like	UniProtKB/TrEMBL
UniProt	A0A8C0LRH4	ENTREZGENE
	A0A8C0RHM0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0S2C4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PYI5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0PN00	ENTREZGENE
UniProt Secondary	A0A8P0PN00	UniProtKB/TrEMBL
VGNC ID	VGNC:38281	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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