GRP (gastrin releasing peptide) - Rat Genome Database

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Gene: GRP (gastrin releasing peptide) Canis lupus familiaris
Analyze
Symbol: GRP
Name: gastrin releasing peptide
RGD ID: 12138150
Description: ENCODES a protein that exhibits neuropeptide hormone activity (inferred); INVOLVED IN cellular response to sodium phosphate (ortholog); mast cell degranulation (ortholog); negative regulation of voltage-gated potassium channel activity (ortholog); ASSOCIATED WITH amnestic disorder (ortholog); Aortic Calcification (ortholog); cerebrovascular disease (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); neuron projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gastrin-releasing peptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1116,974,818 - 16,987,578 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl116,975,113 - 16,987,531 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha117,949,830 - 17,962,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0116,851,713 - 16,864,426 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl116,851,715 - 16,864,617 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1116,887,063 - 16,899,774 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0116,807,873 - 16,820,608 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0117,069,404 - 17,082,115 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1116,974,818 - 16,987,578 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl116,975,113 - 16,987,531 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha117,949,830 - 17,962,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0116,851,713 - 16,864,426 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl116,851,715 - 16,864,617 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1116,887,063 - 16,899,774 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0116,807,873 - 16,820,608 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0117,069,404 - 17,082,115 (-)NCBIUU_Cfam_GSD_1.0
GRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381859,219,189 - 59,230,771 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1859,220,158 - 59,230,774 (+)EnsemblGRCh38hg38GRCh38
GRCh371856,887,390 - 56,898,003 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361855,038,380 - 55,048,983 (+)NCBINCBI36Build 36hg18NCBI36
Build 341855,038,379 - 55,048,980NCBI
Celera1853,605,282 - 53,615,885 (+)NCBICelera
Cytogenetic Map18q21.32NCBI
HuRef1853,595,537 - 53,606,136 (+)NCBIHuRef
CHM1_11856,882,622 - 56,893,227 (+)NCBICHM1_1
T2T-CHM13v2.01859,420,451 - 59,432,025 (+)NCBIT2T-CHM13v2.0
Grp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391866,005,826 - 66,019,670 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1866,005,891 - 66,019,667 (+)EnsemblGRCm39 Ensembl
GRCm381865,872,751 - 65,886,599 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1865,872,820 - 65,886,596 (+)EnsemblGRCm38mm10GRCm38
MGSCv371866,033,148 - 66,046,233 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361865,998,863 - 66,011,948 (+)NCBIMGSCv36mm8
Celera1867,148,374 - 67,161,630 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1838.98NCBI
Grp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81861,658,655 - 61,672,037 (+)NCBIGRCr8
mRatBN7.21859,388,679 - 59,402,061 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1859,388,274 - 59,402,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1861,481,572 - 61,495,017 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01862,180,256 - 62,193,696 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01860,008,373 - 60,021,747 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01861,563,458 - 61,576,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1861,563,053 - 61,576,818 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,759,485 - 60,772,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41862,162,526 - 62,176,328 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11862,236,136 - 62,249,529 (+)NCBI
Celera1857,511,148 - 57,523,903 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Grp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540243,382,552 - 43,393,463 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540243,382,608 - 43,393,452 (+)NCBIChiLan1.0ChiLan1.0
GRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21776,763,081 - 76,776,923 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11862,455,695 - 62,469,561 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01852,614,169 - 52,626,427 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11855,941,405 - 55,953,188 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1855,942,263 - 55,953,188 (+)Ensemblpanpan1.1panPan2
Grp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494430,237,465 - 30,248,354 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364975,476,800 - 5,487,358 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364975,473,293 - 5,487,344 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1161,708,812 - 161,721,782 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11161,708,815 - 161,721,986 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21179,286,730 - 179,292,302 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11820,496,201 - 20,508,551 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1820,496,516 - 20,507,153 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660605,077,640 - 5,091,595 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247924,623,097 - 4,633,570 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247924,623,082 - 4,633,545 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GRP
184 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
5 1 16 13 7 1 6 1 2 15 9 12 12 6

Sequence


Ensembl Acc Id: ENSCAFT00000000157   ⟹   ENSCAFP00000000137
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl116,975,113 - 16,987,531 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000914   ⟹   ENSCAFP00845000684
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl116,851,715 - 16,864,617 (-)Ensembl
RefSeq Acc Id: XM_038464993   ⟹   XP_038320921
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1116,887,063 - 16,899,774 (-)NCBI
RefSeq Acc Id: XM_038525572   ⟹   XP_038381500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0117,069,404 - 17,082,115 (-)NCBI
RefSeq Acc Id: XM_038589777   ⟹   XP_038445705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0116,807,873 - 16,820,608 (-)NCBI
RefSeq Acc Id: XM_038653699   ⟹   XP_038509627
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0116,851,713 - 16,864,426 (-)NCBI
RefSeq Acc Id: XM_861026   ⟹   XP_866119
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1116,974,818 - 16,987,578 (-)NCBI
Dog10K_Boxer_Tasha117,949,830 - 17,962,541 (-)NCBI
Sequence:
RefSeq Acc Id: XP_866119   ⟸   XM_861026
- UniProtKB: P08989 (UniProtKB/Swiss-Prot),   A0A8I3RQW9 (UniProtKB/TrEMBL),   A0A8C0MRC7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000000137   ⟸   ENSCAFT00000000157
RefSeq Acc Id: XP_038320921   ⟸   XM_038464993
RefSeq Acc Id: XP_038445705   ⟸   XM_038589777
RefSeq Acc Id: XP_038509627   ⟸   XM_038653699
- UniProtKB: P08989 (UniProtKB/Swiss-Prot),   A0A8I3RQW9 (UniProtKB/TrEMBL),   A0A8C0MRC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381500   ⟸   XM_038525572
- UniProtKB: P08989 (UniProtKB/Swiss-Prot),   A0A8C0MRC7 (UniProtKB/TrEMBL),   A0A8I3RQW9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845000684   ⟸   ENSCAFT00845000914

Promoters
RGD ID:13681953
Promoter ID:EPDNEW_C21
Type:single initiation site
Name:GRP_1
Description:gastrin releasing peptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1116,987,602 - 16,987,662EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000099 Ensembl, UniProtKB/Swiss-Prot
  ENSCAFG00030009704 UniProtKB/TrEMBL
  ENSCAFG00845000570 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000000157.6 UniProtKB/Swiss-Prot
  ENSCAFT00030017951.1 UniProtKB/TrEMBL
  ENSCAFT00845000914 ENTREZGENE
  ENSCAFT00845000914.1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Bombesin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene GRP ENTREZGENE
PANTHER PTHR16866 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16866:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bombesin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BOMBESIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0MRC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RQW9 ENTREZGENE, UniProtKB/TrEMBL
  GRP_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:53721 ENTREZGENE