PAIP2B (poly(A) binding protein interacting protein 2B) - Rat Genome Database

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Gene: PAIP2B (poly(A) binding protein interacting protein 2B) Canis lupus familiaris
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Symbol: PAIP2B
Name: poly(A) binding protein interacting protein 2B
RGD ID: 12125295
Description: ENCODES a protein that exhibits mRNA regulatory element binding translation repressor activity (inferred); INVOLVED IN negative regulation of translational initiation (inferred); regulation of translation (inferred); ASSOCIATED WITH dystonia (ortholog); Methylmalonyl-CoA Epimerase Deficiency (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polyadenylate-binding protein-interacting protein 2B; polyadenylate-binding protein-interacting protein 2B-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11751,381,891 - 51,388,964 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1751,385,194 - 51,413,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1751,093,113 - 51,101,812 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1752,291,546 - 52,324,229 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11751,318,027 - 51,326,716 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01751,389,806 - 51,398,503 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01751,964,551 - 51,973,260 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PAIP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11751,381,891 - 51,388,964 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1751,385,194 - 51,413,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1751,093,113 - 51,101,812 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1752,291,546 - 52,324,229 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11751,318,027 - 51,326,716 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01751,389,806 - 51,398,503 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01751,964,551 - 51,973,260 (+)NCBIUU_Cfam_GSD_1.0
PAIP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38271,182,738 - 71,227,103 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl271,182,738 - 71,227,103 (-)EnsemblGRCh38hg38GRCh38
GRCh37271,409,868 - 71,454,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36271,263,376 - 71,307,741 (-)NCBINCBI36Build 36hg18NCBI36
Celera271,260,574 - 71,304,932 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef271,146,532 - 71,191,204 (-)NCBIHuRef
CHM1_1271,339,205 - 71,383,545 (-)NCBICHM1_1
T2T-CHM13v2.0271,193,792 - 71,238,156 (-)NCBIT2T-CHM13v2.0
Paip2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,783,040 - 83,808,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,782,383 - 83,808,723 (-)EnsemblGRCm39 Ensembl
GRCm38683,806,058 - 83,831,741 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,805,401 - 83,831,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv37683,756,052 - 83,781,735 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,771,721 - 83,797,322 (-)NCBIMGSCv36mm8
Celera685,789,017 - 85,814,725 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.97NCBI
Paip2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,849,625 - 117,881,021 (-)NCBIGRCr8
mRatBN7.24116,292,001 - 116,323,387 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4116,292,020 - 116,323,379 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,770,507 - 121,801,540 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04117,545,698 - 117,576,726 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04116,159,474 - 116,190,518 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04115,484,676 - 115,516,307 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4115,487,313 - 115,516,296 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04180,073,880 - 180,105,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44118,003,247 - 118,032,312 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14118,247,727 - 118,276,790 (-)NCBI
Celera4105,284,575 - 105,315,731 (-)NCBICelera
Cytogenetic Map4q34NCBI
Paip2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542414,156,768 - 14,190,865 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542414,157,358 - 14,190,865 (+)NCBIChiLan1.0ChiLan1.0
PAIP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21255,161,941 - 55,206,055 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A55,164,684 - 55,208,798 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A71,227,562 - 71,271,642 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A72,728,012 - 72,772,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A72,733,750 - 72,772,036 (-)Ensemblpanpan1.1panPan2
Paip2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629213,337,941 - 13,374,264 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649115,202,794 - 15,233,652 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649115,197,028 - 15,233,652 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAIP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl371,452,538 - 71,499,500 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1371,452,753 - 71,500,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2374,881,371 - 74,940,494 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAIP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11435,930,797 - 35,967,398 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1435,930,819 - 35,972,073 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604576,058,135 - 76,096,127 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Paip2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247622,335,544 - 2,375,376 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247622,335,522 - 2,379,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PAIP2B
62 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000014460   ⟹   ENSCAFP00000013373
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1751,385,194 - 51,412,720 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000072252   ⟹   ENSCAFP00000065062
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1751,385,194 - 51,413,360 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845038386   ⟹   ENSCAFP00845030055
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1752,291,546 - 52,324,229 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845038433   ⟹   ENSCAFP00845030091
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1752,291,635 - 52,320,209 (+)Ensembl
RefSeq Acc Id: XM_005630581   ⟹   XP_005630638
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11751,381,891 - 51,388,964 (-)NCBI
Dog10K_Boxer_Tasha1751,093,113 - 51,101,812 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038499227   ⟹   XP_038355155
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11751,318,027 - 51,326,716 (+)NCBI
RefSeq Acc Id: XM_038561791   ⟹   XP_038417719
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01751,964,551 - 51,973,260 (+)NCBI
RefSeq Acc Id: XM_038625861   ⟹   XP_038481789
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01751,389,806 - 51,398,503 (+)NCBI
RefSeq Acc Id: XM_038691792   ⟹   XP_038547720
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01752,315,541 - 52,324,245 (+)NCBI
RefSeq Acc Id: XM_038691793   ⟹   XP_038547721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBI
RefSeq Acc Id: XM_038691794   ⟹   XP_038547722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBI
RefSeq Acc Id: XM_038691795   ⟹   XP_038547723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBI
RefSeq Acc Id: XM_038691796   ⟹   XP_038547724
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBI
RefSeq Acc Id: XP_005630638   ⟸   XM_005630581
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z621 (UniProtKB/TrEMBL),   A0A8I3PDA7 (UniProtKB/TrEMBL),   A0A8C0PFL5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000013373   ⟸   ENSCAFT00000014460
Ensembl Acc Id: ENSCAFP00000065062   ⟸   ENSCAFT00000072252
RefSeq Acc Id: XP_038355155   ⟸   XM_038499227
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038481789   ⟸   XM_038625861
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038547722   ⟸   XM_038691794
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PMC0 (UniProtKB/TrEMBL),   A0A8C0JJF8 (UniProtKB/TrEMBL),   A0A8I3PD81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038547723   ⟸   XM_038691795
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PMC0 (UniProtKB/TrEMBL),   A0A8C0JJF8 (UniProtKB/TrEMBL),   A0A8I3PD81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038547724   ⟸   XM_038691796
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PMC0 (UniProtKB/TrEMBL),   A0A8C0JJF8 (UniProtKB/TrEMBL),   A0A8I3PD81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038547721   ⟸   XM_038691793
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PMC0 (UniProtKB/TrEMBL),   A0A8C0JJF8 (UniProtKB/TrEMBL),   A0A8I3PD81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038547720   ⟸   XM_038691792
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z621 (UniProtKB/TrEMBL),   A0A8I3PDA7 (UniProtKB/TrEMBL),   A0A8C0PFL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038417719   ⟸   XM_038561791
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PFL5 (UniProtKB/TrEMBL),   A0A8C0Z621 (UniProtKB/TrEMBL),   A0A8I3PDA7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845030091   ⟸   ENSCAFT00845038433
Ensembl Acc Id: ENSCAFP00845030055   ⟸   ENSCAFT00845038386


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009092 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025502 UniProtKB/TrEMBL
  ENSCAFG00040024144 UniProtKB/TrEMBL
  ENSCAFG00845021756 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000014460.5 UniProtKB/TrEMBL
  ENSCAFT00000103391.1 UniProtKB/TrEMBL
  ENSCAFT00030047100.1 UniProtKB/TrEMBL
  ENSCAFT00030047107.1 UniProtKB/TrEMBL
  ENSCAFT00040044984.1 UniProtKB/TrEMBL
  ENSCAFT00040044997.1 UniProtKB/TrEMBL
  ENSCAFT00845038386 ENTREZGENE
  ENSCAFT00845038386.1 UniProtKB/TrEMBL
  ENSCAFT00845038433 ENTREZGENE
  ENSCAFT00845038433.1 UniProtKB/TrEMBL
InterPro Ataxin-2_C UniProtKB/TrEMBL
  PAIP2-like UniProtKB/TrEMBL
KEGG Report cfa:475800 UniProtKB/TrEMBL
NCBI Gene PAIP2B ENTREZGENE
PANTHER POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B UniProtKB/TrEMBL
  PTHR13154 UniProtKB/TrEMBL
Pfam PAM2 UniProtKB/TrEMBL
UniProt A0A8C0JJF8 ENTREZGENE
  A0A8C0PFL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PMC0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z621 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PD81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PDA7 ENTREZGENE, UniProtKB/TrEMBL