RAB3A (RAB3A, member RAS oncogene family) - Rat Genome Database

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Gene: RAB3A (RAB3A, member RAS oncogene family) Canis lupus familiaris
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Symbol: RAB3A
Name: RAB3A, member RAS oncogene family
RGD ID: 12058196
Description: ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); GDP-dissociation inhibitor binding (ortholog); INVOLVED IN axonogenesis (ortholog); lung development (ortholog); maintenance of presynaptic active zone structure (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH Ependymomas (ortholog); Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 (ortholog); FOUND IN axon (ortholog); protein-containing complex (ortholog); secretory granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-3A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,796,740 - 44,802,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,796,895 - 44,801,692 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,710,693 - 44,716,183 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,282,514 - 45,288,006 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,282,528 - 45,287,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,519,685 - 44,525,177 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,930,125 - 44,935,626 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,205,632 - 45,211,124 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAB3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,796,740 - 44,802,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,796,895 - 44,801,692 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,710,693 - 44,716,183 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,282,514 - 45,288,006 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,282,528 - 45,287,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,519,685 - 44,525,177 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,930,125 - 44,935,626 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,205,632 - 45,211,124 (+)NCBIUU_Cfam_GSD_1.0
RAB3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,196,784 - 18,204,042 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,196,784 - 18,204,042 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,307,594 - 18,314,852 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,168,611 - 18,175,839 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,168,610 - 18,175,839NCBI
Celera1918,209,348 - 18,216,613 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,871,059 - 17,878,307 (-)NCBIHuRef
CHM1_11918,307,151 - 18,314,427 (-)NCBICHM1_1
T2T-CHM13v2.01918,330,909 - 18,338,143 (-)NCBIT2T-CHM13v2.0
Rab3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,207,258 - 71,211,276 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,207,328 - 71,211,323 (+)EnsemblGRCm39 Ensembl
GRCm38870,754,703 - 70,758,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,754,679 - 70,758,677 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,278,578 - 73,282,585 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,683,712 - 73,687,666 (+)NCBIMGSCv36mm8
Celera873,315,980 - 73,319,984 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Rab3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,718,164 - 18,722,273 (-)NCBIGRCr8
mRatBN7.21618,684,185 - 18,688,297 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,684,188 - 18,688,336 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,726,559 - 18,730,675 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,859,239 - 19,863,348 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,779,503 - 18,783,622 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,435,098 - 20,439,206 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,435,101 - 20,439,206 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,292,166 - 20,296,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,189,765 - 19,193,874 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,189,765 - 19,193,872 (-)NCBI
Celera1618,876,401 - 18,880,512 (-)NCBICelera
Cytogenetic Map16p14NCBI
Rab3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,221,366 - 3,224,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,220,108 - 3,224,376 (+)NCBIChiLan1.0ChiLan1.0
RAB3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,054,186 - 23,061,417 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,062,526 - 22,069,753 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,672,661 - 17,679,541 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,649,166 - 18,656,768 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,649,166 - 18,656,768 (-)Ensemblpanpan1.1panPan2
Rab3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,441,225 - 203,447,398 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,989,804 - 2,998,305 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,990,367 - 2,995,935 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,603,117 - 59,609,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,603,090 - 59,609,773 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,142,410 - 59,149,077 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,671,388 - 16,678,780 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,670,431 - 16,678,644 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,699,847 - 2,707,085 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,530,312 - 1,536,129 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,532,857 - 1,537,159 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAB3A
63 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000023719   ⟹   ENSCAFP00000022020
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2044,796,895 - 44,801,588 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000075086   ⟹   ENSCAFP00000059521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2044,798,091 - 44,801,692 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845040992   ⟹   ENSCAFP00845032115
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2045,282,528 - 45,287,983 (+)Ensembl
RefSeq Acc Id: XM_038428170   ⟹   XP_038284098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02045,282,514 - 45,288,006 (+)NCBI
RefSeq Acc Id: XM_038503829   ⟹   XP_038359757
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12044,519,685 - 44,525,177 (+)NCBI
RefSeq Acc Id: XM_038566840   ⟹   XP_038422768
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02045,205,632 - 45,211,124 (+)NCBI
RefSeq Acc Id: XM_038630993   ⟹   XP_038486921
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02044,930,125 - 44,935,626 (+)NCBI
RefSeq Acc Id: XM_541942   ⟹   XP_541942
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12044,796,740 - 44,802,224 (+)NCBI
Dog10K_Boxer_Tasha2044,710,693 - 44,716,183 (+)NCBI
Sequence:
RefSeq Acc Id: XP_541942   ⟸   XM_541942
- UniProtKB: A0A8C0RM23 (UniProtKB/TrEMBL),   A0A8C0QZR9 (UniProtKB/TrEMBL),   A0A8I3PDP4 (UniProtKB/TrEMBL),   A0A8C0KGA5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000022020   ⟸   ENSCAFT00000023719
Ensembl Acc Id: ENSCAFP00000059521   ⟸   ENSCAFT00000075086
RefSeq Acc Id: XP_038359757   ⟸   XM_038503829
RefSeq Acc Id: XP_038486921   ⟸   XM_038630993
RefSeq Acc Id: XP_038284098   ⟸   XM_038428170
- UniProtKB: A0A8C0RM23 (UniProtKB/TrEMBL),   A0A8C0QZR9 (UniProtKB/TrEMBL),   A0A8I3PDP4 (UniProtKB/TrEMBL),   A0A8C0KGA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038422768   ⟸   XM_038566840
- UniProtKB: A0A8C0KGA5 (UniProtKB/TrEMBL),   A0A8C0QZR9 (UniProtKB/TrEMBL),   A0A8C0RM23 (UniProtKB/TrEMBL),   A0A8I3PDP4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845032115   ⟸   ENSCAFT00845040992


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014945 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016930 UniProtKB/TrEMBL
  ENSCAFG00040008749 UniProtKB/TrEMBL
  ENSCAFG00845023221 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000075086.2 UniProtKB/TrEMBL
  ENSCAFT00030031302.1 UniProtKB/TrEMBL
  ENSCAFT00030031372.1 UniProtKB/TrEMBL
  ENSCAFT00040016327.1 UniProtKB/TrEMBL
  ENSCAFT00040016359.1 UniProtKB/TrEMBL
  ENSCAFT00845040992 ENTREZGENE
  ENSCAFT00845040992.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rab3 UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Rab UniProtKB/TrEMBL
KEGG Report cfa:484826 UniProtKB/TrEMBL
NCBI Gene RAB3A ENTREZGENE
PANTHER LD44762P UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0KGA5 ENTREZGENE
  A0A8C0QNK0_CANLF UniProtKB/TrEMBL
  A0A8C0QZR9 ENTREZGENE
  A0A8C0RM23 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PDP4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45282 ENTREZGENE