PAIP2B (poly(A) binding protein interacting protein 2B) - Rat Genome Database

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Gene: PAIP2B (poly(A) binding protein interacting protein 2B) Pan paniscus
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Symbol: PAIP2B
Name: poly(A) binding protein interacting protein 2B
RGD ID: 12043889
Description: ENCODES a protein that exhibits mRNA regulatory element binding translation repressor activity (inferred); translation repressor activity (inferred); INVOLVED IN negative regulation of translation (inferred); negative regulation of translational initiation (inferred); regulation of translation (inferred); ASSOCIATED WITH dystonia (ortholog); Methylmalonyl-CoA Epimerase Deficiency (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polyadenylate-binding protein-interacting protein 2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21255,161,941 - 55,206,055 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A55,164,684 - 55,208,798 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A71,227,562 - 71,271,642 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A72,728,012 - 72,772,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A72,733,750 - 72,772,036 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PAIP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21255,161,941 - 55,206,055 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A55,164,684 - 55,208,798 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A71,227,562 - 71,271,642 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A72,728,012 - 72,772,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A72,733,750 - 72,772,036 (-)Ensemblpanpan1.1panPan2
PAIP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38271,182,738 - 71,227,103 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl271,182,738 - 71,227,103 (-)EnsemblGRCh38hg38GRCh38
GRCh37271,409,868 - 71,454,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36271,263,376 - 71,307,741 (-)NCBINCBI36Build 36hg18NCBI36
Celera271,260,574 - 71,304,932 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef271,146,532 - 71,191,204 (-)NCBIHuRef
CHM1_1271,339,205 - 71,383,545 (-)NCBICHM1_1
T2T-CHM13v2.0271,193,792 - 71,238,156 (-)NCBIT2T-CHM13v2.0
Paip2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,783,040 - 83,808,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,782,383 - 83,808,723 (-)EnsemblGRCm39 Ensembl
GRCm38683,806,058 - 83,831,741 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,805,401 - 83,831,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv37683,756,052 - 83,781,735 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,771,721 - 83,797,322 (-)NCBIMGSCv36mm8
Celera685,789,017 - 85,814,725 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.97NCBI
Paip2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,849,625 - 117,881,021 (-)NCBIGRCr8
mRatBN7.24116,292,001 - 116,323,387 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4116,292,020 - 116,323,379 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,770,507 - 121,801,540 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04117,545,698 - 117,576,726 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04116,159,474 - 116,190,518 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04115,484,676 - 115,516,307 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4115,487,313 - 115,516,296 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04180,073,880 - 180,105,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44118,003,247 - 118,032,312 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14118,247,727 - 118,276,790 (-)NCBI
Celera4105,284,575 - 105,315,731 (-)NCBICelera
Cytogenetic Map4q34NCBI
Paip2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542414,156,768 - 14,190,865 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542414,157,358 - 14,190,865 (+)NCBIChiLan1.0ChiLan1.0
PAIP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11751,381,891 - 51,388,964 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1751,385,194 - 51,413,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1751,093,113 - 51,101,812 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01752,291,532 - 52,324,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1752,291,546 - 52,324,229 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11751,318,027 - 51,326,716 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01751,389,806 - 51,398,503 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01751,964,551 - 51,973,260 (+)NCBIUU_Cfam_GSD_1.0
Paip2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629213,337,941 - 13,374,264 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649115,202,794 - 15,233,652 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649115,197,028 - 15,233,652 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAIP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl371,452,538 - 71,499,500 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1371,452,753 - 71,500,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2374,881,371 - 74,940,494 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAIP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11435,930,797 - 35,967,398 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1435,930,819 - 35,972,073 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604576,058,135 - 76,096,127 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Paip2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247622,335,544 - 2,375,376 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247622,335,522 - 2,379,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000052249   ⟹   ENSPPAP00000029400
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A72,733,750 - 72,772,036 (-)Ensembl
RefSeq Acc Id: XM_003808169   ⟹   XP_003808217
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21255,161,941 - 55,206,055 (+)NCBI
NHGRI_mPanPan12A55,164,684 - 55,208,798 (+)NCBI
Mhudiblu_PPA_v02A71,227,562 - 71,271,642 (-)NCBI
PanPan1.12A72,728,012 - 72,772,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008960269   ⟹   XP_008958517
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21255,161,987 - 55,206,055 (+)NCBI
NHGRI_mPanPan12A55,164,731 - 55,208,798 (+)NCBI
Mhudiblu_PPA_v02A71,227,562 - 71,271,637 (-)NCBI
PanPan1.12A72,728,012 - 72,772,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008960270   ⟹   XP_008958518
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21255,162,665 - 55,206,055 (+)NCBI
NHGRI_mPanPan12A55,165,409 - 55,208,798 (+)NCBI
Mhudiblu_PPA_v02A71,227,562 - 71,270,966 (-)NCBI
PanPan1.12A72,728,012 - 72,771,355 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008960271   ⟹   XP_008958519
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21255,162,710 - 55,206,055 (+)NCBI
NHGRI_mPanPan12A55,165,453 - 55,208,798 (+)NCBI
Mhudiblu_PPA_v02A71,227,562 - 71,270,779 (-)NCBI
PanPan1.12A72,728,012 - 72,771,193 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003808217 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958517 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958518 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958519 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000029400
  ENSPPAP00000029400.1
RefSeq Acc Id: XP_008958517   ⟸   XM_008960269
- UniProtKB: A0A2R9BIB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003808217   ⟸   XM_003808169
- UniProtKB: A0A2R9BIB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958518   ⟸   XM_008960270
- UniProtKB: A0A2R9BIB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958519   ⟸   XM_008960271
- UniProtKB: A0A2R9BIB4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000029400   ⟸   ENSPPAT00000052249


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037708 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052249.1 UniProtKB/TrEMBL
InterPro Ataxin-2_C UniProtKB/TrEMBL
  PAIP2-like UniProtKB/TrEMBL
KEGG Report pps:100985603 UniProtKB/TrEMBL
NCBI Gene PAIP2B ENTREZGENE
PANTHER POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B UniProtKB/TrEMBL
  PTHR13154 UniProtKB/TrEMBL
Pfam PAM2 UniProtKB/TrEMBL
UniProt A0A2R9BIB4 ENTREZGENE, UniProtKB/TrEMBL