MIP (major intrinsic protein of lens fiber) - Rat Genome Database

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Gene: MIP (major intrinsic protein of lens fiber) Pan paniscus
Analyze
Symbol: MIP
Name: major intrinsic protein of lens fiber
RGD ID: 12041546
Description: ENCODES a protein that exhibits water channel activity (ortholog); INVOLVED IN canalicular bile acid transport (ortholog); gap junction-mediated intercellular transport (ortholog); lens development in camera-type eye (ortholog); ASSOCIATED WITH cataract (ortholog); cataract 15 multiple types (ortholog); Charcot-Marie-Tooth disease axonal type 2U (ortholog); FOUND IN intracellular canaliculus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,876,677 - 37,882,145 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,873,442 - 37,878,910 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,459,965 - 32,465,465 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,713,470 - 32,718,026 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,713,470 - 32,718,026 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,876,677 - 37,882,145 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,873,442 - 37,878,910 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,459,965 - 32,465,465 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,713,470 - 32,718,026 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,713,470 - 32,718,026 (+)Ensemblpanpan1.1panPan2
MIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,449,502 - 56,456,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,449,502 - 56,469,166 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,843,286 - 56,848,441 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,130,151 - 55,134,696 (-)NCBINCBI36Build 36hg18NCBI36
Build 341255,131,148 - 55,134,709NCBI
Celera1256,496,656 - 56,501,806 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1253,882,327 - 53,887,476 (-)NCBIHuRef
CHM1_11256,810,895 - 56,816,045 (-)NCBICHM1_1
T2T-CHM13v2.01256,417,213 - 56,424,265 (-)NCBIT2T-CHM13v2.0
Mip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,061,679 - 128,067,681 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,061,707 - 128,067,681 (+)EnsemblGRCm39 Ensembl
GRCm3810128,225,810 - 128,231,812 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,225,838 - 128,231,812 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,662,894 - 127,668,867 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,628,787 - 127,634,760 (+)NCBIMGSCv36mm8
Celera10133,261,918 - 133,267,869 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.49NCBI
Mip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,228,089 - 1,237,707 (+)NCBIGRCr8
mRatBN7.27643,502 - 653,121 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7647,315 - 654,400 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,405,806 - 3,411,610 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,281,813 - 5,287,615 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,583,723 - 5,589,495 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,635,743 - 2,642,995 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,635,743 - 2,642,848 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,614,619 - 2,621,871 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,509,023 - 1,516,275 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,509,073 - 1,514,815 (+)NCBI
Celera7525,859 - 533,134 (+)NCBICelera
RH 3.4 Map10194.71RGD
Cytogenetic Map7q11NCBI
Mip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,030,619 - 4,035,656 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,030,619 - 4,035,656 (-)NCBIChiLan1.0ChiLan1.0
MIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110701,385 - 707,005 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10701,387 - 706,151 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10764,593 - 769,360 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010710,356 - 715,983 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10710,358 - 715,134 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110687,429 - 692,195 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010930,541 - 935,310 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,054,262 - 1,059,027 (-)NCBIUU_Cfam_GSD_1.0
Mip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,058,559 - 58,063,768 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646807,856 - 811,729 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646806,467 - 811,676 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,787,826 - 21,793,592 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,789,040 - 21,804,964 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,334,531 - 23,339,133 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,409,592 - 52,415,752 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,410,325 - 52,413,933 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,568,279 - 193,573,741 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,600,405 - 11,603,502 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,600,405 - 11,603,502 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003824912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000065712   ⟹   ENSPPAP00000042781
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1232,713,470 - 32,718,026 (+)Ensembl
RefSeq Acc Id: XM_003824912   ⟹   XP_003824960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21037,876,677 - 37,882,145 (+)NCBI
NHGRI_mPanPan11237,873,442 - 37,878,910 (+)NCBI
Mhudiblu_PPA_v01232,459,965 - 32,465,465 (+)NCBI
PanPan1.11232,713,470 - 32,718,026 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003824960 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000042781.1
RefSeq Acc Id: XP_003824960   ⟸   XM_003824912
- UniProtKB: A0A2R9CLF0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000042781   ⟸   ENSPPAT00000065712


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043947 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065712.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1080.10 UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/TrEMBL
  Aquaporin_transptr UniProtKB/TrEMBL
  MIP UniProtKB/TrEMBL
  MIP_CS UniProtKB/TrEMBL
KEGG Report pps:100970155 UniProtKB/TrEMBL
NCBI Gene MIP ENTREZGENE
PANTHER LENS FIBER MAJOR INTRINSIC PROTEIN UniProtKB/TrEMBL
  PTHR19139 UniProtKB/TrEMBL
Pfam MIP UniProtKB/TrEMBL
PRINTS AQUAPORIN2 UniProtKB/TrEMBL
  MINTRINSICP UniProtKB/TrEMBL
PROSITE MIP UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/TrEMBL
UniProt A0A2R9CLF0 ENTREZGENE, UniProtKB/TrEMBL