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Gene: AQP1 (aquaporin 1 (Colton blood group)) Pan paniscus

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Symbol:

AQP1

Name:

aquaporin 1 (Colton blood group)

RGD ID:

12039930

Description:

ENCODES a protein that exhibits ephrin receptor binding (ortholog); potassium ion transmembrane transporter activity (ortholog); water channel activity (ortholog); INVOLVED IN camera-type eye morphogenesis (ortholog); cell migration (ortholog); corticotropin secretion (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Animal Mammary Neoplasms (ortholog); Aquaporin 1 Deficiency (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); axon terminus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

aquaporin-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	35,722,747 - 35,736,555 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	84,047,527 - 84,061,283 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	31,524,933 - 31,538,602 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	31,644,331 - 31,658,141 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	31,644,331 - 31,658,141 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenoid cystic carcinoma (ISO)

Animal Mammary Neoplasms (ISO)

Aquaporin 1 Deficiency (ISO)

autosomal recessive polycystic kidney disease (ISO)

brain edema (ISO)

carcinoma (ISO)

Cardiac Edema (ISO)

central pontine myelinolysis (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

choledochal cyst (ISO)

diabetes mellitus (ISO)

Ehlers-Danlos syndrome kyphoscoliotic type 2 (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Mammary Neoplasms (ISO)

hydrocephalus (ISO)

hypertension (ISO)

hyperthyroidism (ISO)

intracranial hypertension (ISO)

Pain (ISO)

pleomorphic xanthoastrocytoma (ISO)

retinal vein occlusion (ISO)

Salivary Gland Neoplasms (ISO)

Spinal Cord Injuries (ISO)

status epilepticus (ISO)

toxic shock syndrome (ISO)

uveitis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ammonium transmembrane transport (IEA)

camera-type eye morphogenesis (ISO)

carbon dioxide transmembrane transport (IEA)

carbon dioxide transport (IEA)

cell migration (ISO)

cell volume homeostasis (IEA)

cellular homeostasis (IEA)

cellular hyperosmotic response (IEA)

cellular response to cAMP (IEA)

cellular response to copper ion (IEA)

cellular response to dexamethasone stimulus (IEA)

cellular response to hydrogen peroxide (IEA)

cellular response to hypoxia (IEA)

cellular response to mechanical stimulus (IEA)

cellular response to mercury ion (IEA)

cellular response to nitric oxide (IEA)

cellular response to retinoic acid (IEA)

cellular response to salt stress (IEA)

cellular response to UV (IEA)

cerebrospinal fluid secretion (IEA)

cGMP-mediated signaling (IEA)

corticotropin secretion (ISO)

defense response to Gram-negative bacterium (IEA)

establishment of localization in cell (ISO)

establishment or maintenance of actin cytoskeleton polarity (IEA)

fibroblast migration (ISO)

glomerular filtration (ISO)

glycerol transmembrane transport (IEA)

hydrogen peroxide transmembrane transport (IEA)

hyperosmotic response (IEA,ISO)

intracellular water homeostasis (IEA)

lateral ventricle development (IEA)

lipid digestion (ISO)

metanephric descending thin limb development (ISO)

metanephric glomerulus vasculature development (ISO)

metanephric proximal convoluted tubule segment 2 development (ISO)

metanephric proximal straight tubule development (ISO)

metanephric proximal tubule development (ISO)

monoatomic cation transmembrane transport (IEA)

multicellular organismal-level water homeostasis (IEA,ISO)

negative regulation of apoptotic process (IEA)

nitric oxide transport (IEA)

odontogenesis (IEA)

pancreatic juice secretion (IEA)

positive regulation of angiogenesis (IEA)

positive regulation of epithelial cell migration (ISO)

positive regulation of fibroblast migration (ISO)

positive regulation of fibroblast proliferation (IEA)

positive regulation of lamellipodium assembly (ISO)

positive regulation of saliva secretion (IEA)

potassium ion transmembrane transport (IEA)

potassium ion transport (ISO)

renal water absorption (ISO)

renal water transport (IEA)

response to estrogen (ISO)

response to hormone (ISO)

secretion by cell (ISO)

secretory granule organization (ISO)

sensory perception of pain (ISO)

transepithelial water transport (IEA)

transmembrane transport (IEA)

water transport (IEA,ISO)

wound healing (ISO)

Cellular Component

ankyrin-1 complex (IEA)

apical part of cell (IEA)

apical plasma membrane (IEA,ISO)

axon (ISO)

axon terminus (ISO)

basal plasma membrane (IEA)

basolateral plasma membrane (IEA,ISO)

brush border (IEA)

brush border membrane (IEA)

caveola (ISO)

cytoplasm (IEA)

extracellular exosome (IEA)

membrane (IEA)

neuronal cell body membrane (ISO)

nuclear membrane (IEA)

nucleus (IEA)

plasma membrane (IEA,ISO)

sarcolemma (IEA)

Molecular Function

ammonium channel activity (IEA)

carbon dioxide transmembrane transporter activity (IEA)

channel activity (IEA)

ephrin receptor binding (ISO)

glycerol transmembrane transporter activity (IEA)

hydrogen peroxide channel activity (IEA)

identical protein binding (IEA)

intracellularly cGMP-activated cation channel activity (IEA)

nitric oxide transmembrane transporter activity (IEA)

potassium channel activity (IEA)

potassium ion transmembrane transporter activity (ISO)

protein binding (ISO)

transmembrane transporter activity (IEA)

water channel activity (IEA,ISO)

water transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

amiloride pharmacodynamics pathway (ISO)

bendroflumethiazide pharmacodynamics pathway (ISO)

bumetanide pharmacodynamics pathway (ISO)

chlorothiazide pharmacodynamics pathway (ISO)

chlorthalidone pharmacodynamics pathway (ISO)

cystinuria pathway (ISO)

eplerenone pharmacodynamics pathway (ISO)

etacrynic acid pharmacodynamics pathway (ISO)

furosemide pharmacodynamics pathway (ISO)

Hartnup disease pathway (ISO)

hydrochlorothiazide pharmacodynamics pathway (ISO)

hydroflumethiazide pharmacodynamics pathway (ISO)

iminoglycinuria pathway (ISO)

lysinuric protein intolerance pathway (ISO)

metolazone pharmacodynamics pathway (ISO)

spironolactone pharmacodynamics pathway (ISO)

torasemide pharmacodynamics pathway (ISO)

triamterene pharmacodynamics pathway (ISO)

trichlormethiazide pharmacodynamics pathway (ISO)

water transport pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

AQP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	35,722,747 - 35,736,555 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	84,047,527 - 84,061,283 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	31,524,933 - 31,538,602 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	31,644,331 - 31,658,141 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	31,644,331 - 31,658,141 (+)	Ensembl	panpan1.1		panPan2

AQP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	30,911,853 - 30,925,516 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	30,911,853 - 30,925,517 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	30,951,468 - 30,965,131 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	30,917,993 - 30,931,656 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	30,724,707 - 30,738,371	NCBI
Celera	7	30,940,621 - 30,954,337 (+)	NCBI		Celera
Cytogenetic Map	7	p14.3	NCBI
HuRef	7	30,833,637 - 30,847,351 (+)	NCBI		HuRef
CHM1_1	7	30,951,350 - 30,965,064 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	31,049,501 - 31,063,163 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	31,000,921 - 31,014,637 (+)	NCBI

Aqp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	55,313,284 - 55,325,540 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	55,313,417 - 55,325,540 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	55,336,299 - 55,348,555 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	55,336,432 - 55,348,555 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	55,286,293 - 55,298,549 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	55,266,010 - 55,278,133 (+)	NCBI		MGSCv36	mm8
Celera	6	55,870,108 - 55,882,362 (+)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	27.38	NCBI

Aqp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	85,812,784 - 85,824,964 (+)	NCBI		GRCr8
mRatBN7.2	4	84,482,512 - 84,494,690 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	84,482,512 - 84,494,690 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	89,700,946 - 89,713,083 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	85,476,356 - 85,488,493 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	83,882,115 - 83,894,263 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	85,551,503 - 85,563,683 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	85,551,502 - 85,569,360 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	150,203,461 - 150,215,641 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	84,098,346 - 84,110,524 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	84,384,810 - 84,396,991 (+)	NCBI
Celera	4	79,349,727 - 79,361,905 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Aqp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	32,066,196 - 32,078,717 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	32,066,196 - 32,078,661 (+)	NCBI	ChiLan1.0	ChiLan1.0

AQP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	43,592,266 - 43,603,903 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	43,578,721 - 43,605,720 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	43,024,519 - 43,036,159 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	43,532,873 - 43,544,517 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	43,532,714 - 43,546,331 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	43,648,522 - 43,660,154 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	43,325,031 - 43,336,701 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	43,686,308 - 43,697,947 (+)	NCBI		UU_Cfam_GSD_1.0

Aqp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	87,935,407 - 87,948,638 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	7,147,027 - 7,160,401 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	7,146,997 - 7,160,369 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AQP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	42,063,485 - 42,076,746 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	42,063,482 - 42,076,741 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

AQP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	27,456,553 - 27,473,196 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	27,456,259 - 27,470,728 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	77,234,082 - 77,247,886 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aqp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624783	164,609 - 177,766 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624783	164,615 - 177,317 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008958896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024929516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034963880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000044669 ⟹ ENSPPAP00000021865

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	31,644,331 - 31,658,141 (+)	Ensembl

RefSeq Acc Id:

XM_008958896 ⟹ XP_008957144

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	35,722,747 - 35,736,555 (+)	NCBI
NHGRI_mPanPan1	7	84,047,531 - 84,061,283 (+)	NCBI
Mhudiblu_PPA_v0	7	31,524,933 - 31,538,602 (+)	NCBI
PanPan1.1	7	31,644,331 - 31,658,141 (+)	NCBI

Sequence:

show sequence

AAGGAAAAAGTTGGCAGGCCGACAGCACAGCCGTGTCTGCATCCATCCAGAGGAGGTCTGTGTG
GTGTGGGGCGGGCCAGGAGCGGAGAGAGGCCTTCCTCCCTTTGTGCTCCCCCCGCCCCCCGGCC
CTATAAATAGGCCCAGCCCAGGCTGTGGCTCAGCTCTCAGAGGGAATTGAGCACCCGGCAGCGG
TCTCAGGCCAAGCCCCCTGCCAGCATGGCCAGCGAGTTCAAGAAGAAGCTCTTCTGGAGGGCAG
TGGTGGCCGAGTTCCTGGCCACGACCCTCTTTGTCTTCATCAGCATCGGTTCTGCCCTGGGCTT
CAAATACCCGGTGGGGAACAACCAGACGGCGGTCCAGGACAACGTGAAGGTGTCGCTGGCCTTC
GGGCTGAGCATCGCCACGCTGGCGCAGAGTGTGGGCCACATCAGCGGCGCCCACCTCAACCCGG
CTGTCACACTGGGGCTGCTGCTCAGCTGCCAGATCAGCATCTTCCGTGCCCTCATGTACATCAT
CGCCCAGTGCGTGGGGGCCATCGTCGCCACCGCCATCCTCTCAGGCATCACCTCCTCCCTGAAT
GGGAACTCGCTTGGCCGCAATGACCTGGCTGATGGTGTGAACTCGGGCCAGGGCCTGGGCATCG
AGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGCGA
CCTTGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATT
GACTACACTGGCTGTGGGATTAACCCTGCTCGGTCCTTCGGCTCTGCGGTGATCACACACAACT
TCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGTACTCATCTA
CGACTTCATCCTGGCCCCACGCAGTAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGC
CAGGTGGAGGAGTATGACCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAAT
AGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAGGGGCGGGCGGAGGGAGGGGAG
GGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCA
GACCTGCATGGTCAAGCCTCTTATGGGGGTGTTTCTATCTCTTTCTTTCTCTTTCTGTTTCCTG
GCCTCAGAGCTTCCTGGGGACCAAGATTTTCCAATTCACCCACTCCCTTGAAGTTGTGGAGGAG
GTGAAAGAAAGGGACCCACCTGCTAGTTGCCCCTCAGAGCATGATGGGAGGTGTGCCAGAAAGT
CCCCCCTCGCCCCAAAGTTGCTCACCGACTCACCTGCGCAAGTGCCTGGGATTCTACCGTAATT
GCTTTGTGCCTTTGGGCACGGCCCTCCTTCTTTTCCTAACATGCACCTTGCTCCCAATGGTGCT
TGGAGGGGGAAGAGATCCCAGGAGGTGCAGTGGAGGGGGCAAGCTTTGCTCCTTCAGTTCTGCT
TGCTCCCAAGCCCCCGACCCGCTCGGACTTACTGCCTGACCTTGGAATCGTCCCTATATCAGGG
CCTCAGTGACCTCCTTCTGCAAAGTGGCAGGGACTGGCAGAGCTCTACAGGCCTGCAGCCCCTA
AGTGCAGACACAGCATGGGTCCAGAAGACGTGGTCTAGACCAGGGCTGCTCTTTCCACTTGCCC
TGTGTTCTTTCCCCAGGGGCATGACTGTCGCCACACGCCTCTGTGTACATGTGTGCAGAGCAGA
CAGGCTACAAAGCAGAGATCGACAGACAGCCAGGTAGTTGGAACTTTCTGTTCCCTATGGAGAG
GCTTCCCTACACAGGGCCTGCTATTGCAGAATGAAGCCATTTAGAGGGTGAAGGAGAAATACCC
ATGTTACTTCTCTGAGTTTTAGTTGGTCTTTCCATCTATCACCGCATTATCTTGCTCATTCTTC
AGTTCTCTACTCCCTCTTGTCAGTGTAGACACAGGTCACCATTATGCTGGTGTATGTTTATCAA
AGAGCACTTGAGCTGTCTGAAGCCCAAAGCCTGAGGACAGAAAGACCCTGATGCAGGTCAGCCC
ATGGAGGCAGATGCCCTTGCTGGGCCTGGGGGTTTTCCAAGCCCTCAGCTGGTCCTGACCAGGA
TGGAGCAAGCTCTTCTCTTGCTCATGAGCTCCTGATCAGAGGCATTTGAGCAGCTGAATAACCT
GCACAGGCTTGCTGTATGACCCCTGGCCACAGCCTTCCCTCTGCATTGACCTGGAGGGGAGAGG
TCAGCCTTGACCTGATGAGGTAGCTATAGTTGCAGCCCAAGGACAGTTCAGAGATCAGGATCAG
CTTTGAAGGCTGAATTCTATCTACATAAGTCCTTTCAATTCCACCAGGGCCAGAGCAGCTCCAC
CACTGTGCACTTAGCCATGATGGCAACAGAAACCAAGAGACACAATTACGCAGGTATTTAGAAG
CAGAGGGACAACCAGAAGGCCCTTAACTATCACCAGTGCATCACATCTGCACACTCTCTTCTCC
ATTCCCTAGCAGGAACTTCTAGCTCATTTAACAGATAAAGAAACTGAGGCCCACGGTTTCAGCT
AGACAATGATTTGGCCAGGCCTAGTAACCAAGGCCCTGTCTCTGGCTACTCCCTGGACCACAAG
GCTGATTCCTCTCATTTCCAGCTTCTCAGTTTCTGCCTGGGCAATGGCCAGGGGCCAGGAGTGG
GGAGAGTTGTGATGGAGGGGAGAGGGGGCACACCCACCCCCTGCCTGGTTCTAGGCTGCTGCAC
ACCAAGGCCCTGCATCTGTCTGCTCTGCATATATGTCTCTTTGGAGTTGGAATTTCATTATATG
TTAAGAAAATAAAGGAAAATGACTTGTAAGATC

hide sequence

RefSeq Acc Id:

XM_024929516 ⟹ XP_024785284

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	35,722,798 - 35,736,555 (+)	NCBI
NHGRI_mPanPan1	7	84,047,527 - 84,061,283 (+)	NCBI
Mhudiblu_PPA_v0	7	31,524,933 - 31,538,602 (+)	NCBI
PanPan1.1	7	31,644,331 - 31,658,141 (+)	NCBI

Sequence:

show sequence

AAGGAAAAAGTTGGCAGGCCGACAGCACAGCCGTGTCTGCATCCATCCAGAGGAGGTCTGTGTG
GTGTGGGGCGGGCCAGGAGCGGAGAGAGGCCTTCCTCCCTTTGTGCTCCCCCCGCCCCCCGGCC
CTATAAATAGGCCCAGCCCAGGCTGTGGCTCAGCTCTCAGAGGGAATTGAGCACCCGGCAGCGG
TCTCAGGCCAAGCCCCCTGCCAGCATGGCCAGCGAGTTCAAGAAGAAGCTCTTCTGGAGGGCAG
TGGTGGCCGAGTTCCTGGCCACGACCCTCTTTGTCTTCATCAGCATCGGTTCTGCCCTGGGCTT
CAAATACCCGGTGGGGAACAACCAGACGGCGGTCCAGGACAACGTGAAGGTGTCGCTGGCCTTC
GGGCTGAGCATCGCCACGCTGGCGCAGAGTGTGGGCCACATCAGCGGCGCCCACCTCAACCCGG
CTGTCACACTGGGGCTGCTGCTCAGCTGCCAGATCAGCATCTTCCGTGCCCTCATGTACATCAT
CGCCCAGTGCGTGGGGGCCATCGTCGCCACCGCCATCCTCTCAGGCATCACCTCCTCCCTGAAT
GGGAACTCGCTTGGCCGCAATGACCTGGCTGATGGTGTGAACTCGGGCCAGGGCCTGGGCATCG
AGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGCGA
CCTTGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCTATT
GACTACACTGGCTGTGGGATTAACCCTGCTCGGTCCTTCGGCTCTGCGGTGATCACACACAACT
TCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTGTACTCATCTA
CGACTTCATCCTGGCCCCACGCAGTAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAGCGGC
CAGGTGGAGGAGTATGACCTGGATGCCGACGACATCAACTCCAGGAGCTTCCTGGGGACCAAGA
TTTTCCAATTCACCCACTCCCTTGAAGTTGTGGAGGAGGTGAAAGAAAGGGACCCACCTGCTAG
TTGCCCCTCAGAGCATGATGGGAGGTGTGCCAGAAAGTCCCCCCTCGCCCCAAAGTTGCTCACC
GACTCACCTGCGCAAGTGCCTGGGATTCTACCGTAATTGCTTTGTGCCTTTGGGCACGGCCCTC
CTTCTTTTCCTAACATGCACCTTGCTCCCAATGGTGCTTGGAGGGGGAAGAGATCCCAGGAGGT
GCAGTGGAGGGGGCAAGCTTTGCTCCTTCAGTTCTGCTTGCTCCCAAGCCCCCGACCCGCTCGG
ACTTACTGCCTGACCTTGGAATCGTCCCTATATCAGGGCCTCAGTGACCTCCTTCTGCAAAGTG
GCAGGGACTGGCAGAGCTCTACAGGCCTGCAGCCCCTAAGTGCAGACACAGCATGGGTCCAGAA
GACGTGGTCTAGACCAGGGCTGCTCTTTCCACTTGCCCTGTGTTCTTTCCCCAGGGGCATGACT
GTCGCCACACGCCTCTGTGTACATGTGTGCAGAGCAGACAGGCTACAAAGCAGAGATCGACAGA
CAGCCAGGTAGTTGGAACTTTCTGTTCCCTATGGAGAGGCTTCCCTACACAGGGCCTGCTATTG
CAGAATGAAGCCATTTAGAGGGTGAAGGAGAAATACCCATGTTACTTCTCTGAGTTTTAGTTGG
TCTTTCCATCTATCACCGCATTATCTTGCTCATTCTTCAGTTCTCTACTCCCTCTTGTCAGTGT
AGACACAGGTCACCATTATGCTGGTGTATGTTTATCAAAGAGCACTTGAGCTGTCTGAAGCCCA
AAGCCTGAGGACAGAAAGACCCTGATGCAGGTCAGCCCATGGAGGCAGATGCCCTTGCTGGGCC
TGGGGGTTTTCCAAGCCCTCAGCTGGTCCTGACCAGGATGGAGCAAGCTCTTCTCTTGCTCATG
AGCTCCTGATCAGAGGCATTTGAGCAGCTGAATAACCTGCACAGGCTTGCTGTATGACCCCTGG
CCACAGCCTTCCCTCTGCATTGACCTGGAGGGGAGAGGTCAGCCTTGACCTGATGAGGTAGCTA
TAGTTGCAGCCCAAGGACAGTTCAGAGATCAGGATCAGCTTTGAAGGCTGAATTCTATCTACAT
AAGTCCTTTCAATTCCACCAGGGCCAGAGCAGCTCCACCACTGTGCACTTAGCCATGATGGCAA
CAGAAACCAAGAGACACAATTACGCAGGTATTTAGAAGCAGAGGGACAACCAGAAGGCCCTTAA
CTATCACCAGTGCATCACATCTGCACACTCTCTTCTCCATTCCCTAGCAGGAACTTCTAGCTCA
TTTAACAGATAAAGAAACTGAGGCCCACGGTTTCAGCTAGACAATGATTTGGCCAGGCCTAGTA
ACCAAGGCCCTGTCTCTGGCTACTCCCTGGACCACAAGGCTGATTCCTCTCATTTCCAGCTTCT
CAGTTTCTGCCTGGGCAATGGCCAGGGGCCAGGAGTGGGGAGAGTTGTGATGGAGGGGAGAGGG
GGCACACCCACCCCCTGCCTGGTTCTAGGCTGCTGCACACCAAGGCCCTGCATCTGTCTGCTCT
GCATATATGTCTCTTTGGAGTTGGAATTTCATTATATGTTAAGAAAATAAAGGAAAATGACTTG
TAAGATC

hide sequence

RefSeq Acc Id:

XM_034963880 ⟹ XP_034819771

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	35,732,446 - 35,736,555 (+)	NCBI
NHGRI_mPanPan1	7	84,057,174 - 84,061,283 (+)	NCBI
Mhudiblu_PPA_v0	7	31,534,503 - 31,538,602 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008957144	(Get FASTA)	NCBI Sequence Viewer
	XP_024785284	(Get FASTA)	NCBI Sequence Viewer
	XP_034819771	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000021865
	ENSPPAP00000021865.1

RefSeq Acc Id:	XP_008957144 ⟸ XM_008958896
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9B319 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLA QSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLNGNSLGRND LADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGIN PARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLD ADDINSRVEMKPK hide sequence

RefSeq Acc Id:

XP_024785284 ⟸ XM_024929516

- Peptide Label:

isoform X3

- Sequence:

show sequence

MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLA
QSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLNGNSLGRND
LADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGIN
PARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLD
ADDINSRSFLGTKIFQFTHSLEVVEEVKERDPPASCPSEHDGRCARKSPLAPKLLTDSPAQVPG
ILP

hide sequence

RefSeq Acc Id:	XP_034819771 ⟸ XM_034963880
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSPPAP00000021865 ⟸ ENSPPAT00000044669

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034128	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000044669.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1080.10	UniProtKB/TrEMBL
InterPro	Aquaporin-like	UniProtKB/TrEMBL
	Aquaporin_1	UniProtKB/TrEMBL
	Aquaporin_transptr	UniProtKB/TrEMBL
	MIP	UniProtKB/TrEMBL
	MIP_CS	UniProtKB/TrEMBL
KEGG Report	pps:103784130	UniProtKB/TrEMBL
NCBI Gene	AQP1	ENTREZGENE
PANTHER	AQUAPORIN-1	UniProtKB/TrEMBL
	PTHR19139	UniProtKB/TrEMBL
Pfam	MIP	UniProtKB/TrEMBL
PRINTS	AQUAPORIN1	UniProtKB/TrEMBL
	MINTRINSICP	UniProtKB/TrEMBL
PROSITE	MIP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF81338	UniProtKB/TrEMBL
UniProt	A0A2R9B319	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB