LAMP1 (lysosomal associated membrane protein 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: LAMP1 (lysosomal associated membrane protein 1) Pan paniscus
Analyze
Symbol: LAMP1
Name: lysosomal associated membrane protein 1
RGD ID: 12032245
Description: ENCODES a protein that exhibits enzyme binding (inferred); ion channel inhibitor activity (inferred); protein domain specific binding (inferred); INVOLVED IN autophagic cell death (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH factor X deficiency (ortholog); Streptococcus pneumonia (ortholog); FOUND IN alveolar lamellar body (ortholog); cell surface (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lysosome-associated membrane glycoprotein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,800,586 - 114,826,384 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113113,491,024 - 113,515,539 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01394,442,507 - 94,464,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113113,507,400 - 113,530,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,507,401 - 113,530,457 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LAMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,800,586 - 114,826,384 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113113,491,024 - 113,515,539 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01394,442,507 - 94,464,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113113,507,400 - 113,530,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,507,401 - 113,530,457 (+)Ensemblpanpan1.1panPan2
LAMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813113,297,239 - 113,323,672 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13113,297,239 - 113,323,672 (+)EnsemblGRCh38hg38GRCh38
GRCh3713113,951,554 - 113,977,987 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,999,470 - 113,025,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413112,999,602 - 113,025,741NCBI
Celera1394,778,100 - 94,804,252 (+)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1394,390,382 - 94,416,378 (+)NCBIHuRef
CHM1_113113,920,516 - 113,946,732 (+)NCBICHM1_1
T2T-CHM13v2.013112,550,907 - 112,577,228 (+)NCBIT2T-CHM13v2.0
Lamp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,209,161 - 13,225,338 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,209,161 - 13,225,338 (+)EnsemblGRCm39 Ensembl
GRCm38813,159,161 - 13,175,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,159,161 - 13,175,338 (+)EnsemblGRCm38mm10GRCm38
MGSCv37813,159,135 - 13,175,338 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,159,256 - 13,175,315 (+)NCBIMGSCv36mm8
Celera813,327,454 - 13,343,657 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
Lamp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81683,058,131 - 83,082,843 (-)NCBIGRCr8
mRatBN7.21676,355,982 - 76,380,700 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1676,355,984 - 76,381,883 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,636,784 - 81,653,472 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01685,089,361 - 85,106,049 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01680,324,785 - 80,354,680 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,689,576 - 81,714,341 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,689,335 - 81,714,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01681,175,574 - 81,200,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,213,165 - 81,230,019 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11681,213,425 - 81,230,284 (-)NCBI
Celera1674,162,536 - 74,179,021 (-)NCBICelera
RH 3.4 Map16744.4RGD
Cytogenetic Map16q12.5NCBI
Lamp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404557,862 - 573,379 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404557,090 - 573,532 (-)NCBIChiLan1.0ChiLan1.0
LAMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12260,678,116 - 60,695,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2260,678,111 - 60,694,924 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,390,142 - 60,407,645 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02261,363,372 - 61,380,853 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2261,304,300 - 61,380,844 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12260,802,204 - 60,819,682 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02260,804,391 - 60,821,868 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02260,835,472 - 60,852,955 (+)NCBIUU_Cfam_GSD_1.0
Lamp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,563,024 - 195,574,796 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936472378,173 - 389,381 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936472377,359 - 389,121 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,600,645 - 78,617,616 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,600,818 - 78,617,587 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,117,963 - 86,134,737 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,295,758 - 91,319,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,295,681 - 91,321,333 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604648,343,222 - 48,368,545 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lamp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793661,342 - 675,675 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793661,322 - 675,603 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000046422   ⟹   ENSPPAP00000023597
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl13113,507,401 - 113,530,180 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000046442   ⟹   ENSPPAP00000023617
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl13113,512,300 - 113,530,457 (+)Ensembl
RefSeq Acc Id: XM_034937047   ⟹   XP_034792938
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,800,586 - 114,826,384 (+)NCBI
NHGRI_mPanPan113113,491,024 - 113,515,539 (+)NCBI
Mhudiblu_PPA_v01394,442,510 - 94,464,061 (+)NCBI
RefSeq Acc Id: XM_034937048   ⟹   XP_034792939
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,800,586 - 114,826,384 (+)NCBI
NHGRI_mPanPan113113,491,121 - 113,515,539 (+)NCBI
Mhudiblu_PPA_v01394,442,507 - 94,463,431 (+)NCBI
RefSeq Acc Id: XR_010109698
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,800,586 - 114,826,384 (+)NCBI
RefSeq Acc Id: XR_010109699
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v214114,800,586 - 114,826,384 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034792938 (Get FASTA)   NCBI Sequence Viewer  
  XP_034792939 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000023597.1
  ENSPPAP00000023617.1
RefSeq Acc Id: XP_034792939   ⟸   XM_034937048
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B8K5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034792938   ⟸   XM_034937047
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B8K5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000023597   ⟸   ENSPPAT00000046422
Ensembl Acc Id: ENSPPAP00000023617   ⟸   ENSPPAT00000046442

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034963 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046422.1 UniProtKB/TrEMBL
  ENSPPAT00000046442.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.160.110 UniProtKB/TrEMBL
InterPro Lamp2-like_luminal UniProtKB/TrEMBL
  Lamp2-like_TM UniProtKB/TrEMBL
  LAMP_CS UniProtKB/TrEMBL
  Lysosome-assoc_membr_glycop UniProtKB/TrEMBL
NCBI Gene LAMP1 ENTREZGENE
PANTHER LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 UniProtKB/TrEMBL
  PTHR11506 UniProtKB/TrEMBL
Pfam Lamp UniProtKB/TrEMBL
  Lamp2_2nd UniProtKB/TrEMBL
PRINTS LYSASSOCTDMP UniProtKB/TrEMBL
PROSITE LAMP_1 UniProtKB/TrEMBL
  LAMP_2 UniProtKB/TrEMBL
  LAMP_3 UniProtKB/TrEMBL
UniProt A0A2R9B8K5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B8N2_PANPA UniProtKB/TrEMBL