ATG16L1 (autophagy related 16 like 1) - Rat Genome Database

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Gene: ATG16L1 (autophagy related 16 like 1) Pan paniscus
Analyze
Symbol: ATG16L1
Name: autophagy related 16 like 1
RGD ID: 12003278
Description: ENCODES a protein that exhibits GTPase binding (inferred); identical protein binding (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN C-terminal protein lipidation (ortholog); corpus callosum development (ortholog); dendrite arborization (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Crohn's disease (ortholog); inflammatory bowel disease (ortholog); FOUND IN autophagosome membrane (ortholog); endolysosome membrane (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: autophagy-related protein 16-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,853,482 - 135,897,461 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,868,447 - 135,912,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,479,534 - 120,523,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,392,990 - 239,436,766 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ATG16L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,853,482 - 135,897,461 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,868,447 - 135,912,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,479,534 - 120,523,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,392,990 - 239,436,766 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensemblpanpan1.1panPan2
ATG16L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,251,673 - 233,295,669 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2233,210,051 - 233,295,674 (+)EnsemblGRCh38hg38GRCh38
GRCh372234,160,319 - 234,204,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,824,956 - 233,869,059 (+)NCBINCBI36Build 36hg18NCBI36
Celera2227,881,745 - 227,925,836 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,960,992 - 226,005,094 (+)NCBIHuRef
CHM1_12234,166,299 - 234,210,402 (+)NCBICHM1_1
T2T-CHM13v2.02233,739,756 - 233,783,753 (+)NCBIT2T-CHM13v2.0
Atg16l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,683,730 - 87,720,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,683,592 - 87,720,150 (+)EnsemblGRCm39 Ensembl
GRCm38187,756,007 - 87,792,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,755,870 - 87,792,428 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,652,646 - 89,688,997 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36189,587,242 - 89,623,593 (+)NCBIMGSCv36mm8
Celera190,714,013 - 90,750,352 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.44NCBI
Atg16l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,869,839 - 95,905,354 (+)NCBIGRCr8
mRatBN7.2988,420,737 - 88,457,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,846,724 - 96,882,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,982,902 - 102,018,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,350,405 - 100,385,741 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,879,876 - 94,915,231 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,879,745 - 94,915,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,599,174 - 94,634,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,712,122 - 86,747,370 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,895,541 - 86,929,665 (+)NCBI
Celera985,830,765 - 85,865,957 (+)NCBICelera
Cytogenetic Map9q35NCBI
Atg16l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554532,880,928 - 2,917,581 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554532,884,497 - 2,917,581 (-)NCBIChiLan1.0ChiLan1.0
ATG16L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,761,034 - 44,800,033 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,761,185 - 44,798,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2545,256,465 - 45,295,672 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02545,020,993 - 45,060,197 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2545,020,983 - 45,060,197 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,945,410 - 44,984,592 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,791,409 - 44,830,551 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,946,602 - 44,985,778 (+)NCBIUU_Cfam_GSD_1.0
Atg16l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,929,271 - 186,966,233 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365253,972,558 - 4,010,514 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365253,973,574 - 4,010,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG16L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,651,298 - 133,693,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,651,294 - 133,693,472 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,677,835 - 147,718,756 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATG16L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110119,286,609 - 119,331,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10119,286,751 - 119,333,267 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604080,173,329 - 80,218,029 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg16l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,805,069 - 5,838,741 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,797,725 - 5,838,768 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000050852   ⟹   ENSPPAP00000028008
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050860   ⟹   ENSPPAP00000028016
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050864   ⟹   ENSPPAP00000028020
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050867   ⟹   ENSPPAP00000028023
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050881   ⟹   ENSPPAP00000028037
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B239,393,247 - 239,435,447 (+)Ensembl
RefSeq Acc Id: XM_003813130   ⟹   XP_003813178
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,507 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,472 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,614 - 120,523,563 (+)NCBI
PanPan1.12B239,392,990 - 239,436,766 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003813131   ⟹   XP_003813179
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,482 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,447 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,614 - 120,523,563 (+)NCBI
PanPan1.12B239,392,990 - 239,436,766 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008965720   ⟹   XP_008963968
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,507 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,472 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,614 - 120,523,563 (+)NCBI
PanPan1.12B239,392,990 - 239,436,766 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008965723   ⟹   XP_008963971
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,509 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,475 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,613 - 120,523,563 (+)NCBI
PanPan1.12B239,393,082 - 239,436,766 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008965725   ⟹   XP_008963973
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,509 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,476 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,534 - 120,523,563 (+)NCBI
PanPan1.12B239,392,990 - 239,436,766 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034955377   ⟹   XP_034811268
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,508 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,475 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,613 - 120,523,563 (+)NCBI
RefSeq Acc Id: XM_034955378   ⟹   XP_034811269
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,509 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,475 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,613 - 120,523,563 (+)NCBI
RefSeq Acc Id: XM_034955379   ⟹   XP_034811270
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,508 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,475 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,613 - 120,523,563 (+)NCBI
RefSeq Acc Id: XM_034955380   ⟹   XP_034811271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,690 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,654 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,783 - 120,523,563 (+)NCBI
RefSeq Acc Id: XM_034955381   ⟹   XP_034811272
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,509 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,475 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,614 - 120,523,563 (+)NCBI
RefSeq Acc Id: XM_034955382   ⟹   XP_034811273
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213135,853,508 - 135,897,461 (+)NCBI
NHGRI_mPanPan12B135,868,475 - 135,912,425 (+)NCBI
Mhudiblu_PPA_v02B120,479,613 - 120,523,563 (+)NCBI
RefSeq Acc Id: XP_008963968   ⟸   XM_008965720
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BFM6 (UniProtKB/TrEMBL),   A0A2R9BID4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813178   ⟸   XM_003813130
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BMW5 (UniProtKB/TrEMBL),   A0A2R9BID4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813179   ⟸   XM_003813131
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BEF8 (UniProtKB/TrEMBL),   A0A2R9BID4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008963973   ⟸   XM_008965725
- Peptide Label: isoform X10
- UniProtKB: A0A2R9BFN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008963971   ⟸   XM_008965723
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_034811268   ⟸   XM_034955377
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BID4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811269   ⟸   XM_034955378
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BID4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811270   ⟸   XM_034955379
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BID4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811273   ⟸   XM_034955382
- Peptide Label: isoform X8
RefSeq Acc Id: XP_034811272   ⟸   XM_034955381
- Peptide Label: isoform X7
- UniProtKB: A0A2R9BID4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811271   ⟸   XM_034955380
- Peptide Label: isoform X7
- UniProtKB: A0A2R9BID4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000028037   ⟸   ENSPPAT00000050881
Ensembl Acc Id: ENSPPAP00000028008   ⟸   ENSPPAT00000050852
Ensembl Acc Id: ENSPPAP00000028020   ⟸   ENSPPAT00000050864
Ensembl Acc Id: ENSPPAP00000028016   ⟸   ENSPPAT00000050860
Ensembl Acc Id: ENSPPAP00000028023   ⟸   ENSPPAT00000050867
Protein Domains
Autophagy-related protein


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037037 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050852.1 UniProtKB/TrEMBL
  ENSPPAT00000050860.1 UniProtKB/TrEMBL
  ENSPPAT00000050864.1 UniProtKB/TrEMBL
  ENSPPAT00000050867.1 UniProtKB/TrEMBL
  ENSPPAT00000050881.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro ATG16 UniProtKB/TrEMBL
  Autophagy-rel_prot_16 UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100988004 UniProtKB/TrEMBL
NCBI Gene ATG16L1 ENTREZGENE
PANTHER AUTOPHAGY-RELATED PROTEIN 16-1 UniProtKB/TrEMBL
  PTHR19878 UniProtKB/TrEMBL
Pfam ATG16 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9BEF8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BFM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BFN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BID4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BMW5 ENTREZGENE, UniProtKB/TrEMBL