EIF4EBP2 (eukaryotic translation initiation factor 4E binding protein 2) - Rat Genome Database

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Gene: EIF4EBP2 (eukaryotic translation initiation factor 4E binding protein 2) Pan paniscus
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Symbol: EIF4EBP2
Name: eukaryotic translation initiation factor 4E binding protein 2
RGD ID: 11998251
Description: ENCODES a protein that exhibits eukaryotic initiation factor 4E binding (inferred); translation repressor activity (inferred); INVOLVED IN insulin receptor signaling pathway (ortholog); memory (ortholog); modulation of chemical synaptic transmission (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); familial hemophagocytic lymphohistiocytosis 2 (ortholog); FOUND IN intracellular membraneless organelle (ortholog); neuronal ribonucleoprotein granule (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: eukaryotic translation initiation factor 4E-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2882,559,591 - 82,582,914 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11082,564,915 - 82,583,535 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01066,879,744 - 66,903,027 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11069,399,268 - 69,430,119 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1069,406,745 - 69,423,249 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EIF4EBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2882,559,591 - 82,582,914 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11082,564,915 - 82,583,535 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01066,879,744 - 66,903,027 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11069,399,268 - 69,430,119 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1069,406,745 - 69,423,249 (+)Ensemblpanpan1.1panPan2
EIF4EBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381070,404,145 - 70,428,618 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1070,404,145 - 70,428,618 (+)EnsemblGRCh38hg38GRCh38
GRCh371072,163,901 - 72,188,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361071,833,928 - 71,853,676 (+)NCBINCBI36Build 36hg18NCBI36
Build 341071,833,927 - 71,853,675NCBI
Celera1065,444,292 - 65,468,805 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1066,157,695 - 66,182,214 (+)NCBIHuRef
CHM1_11072,446,090 - 72,470,594 (+)NCBICHM1_1
T2T-CHM13v2.01071,273,202 - 71,298,049 (+)NCBIT2T-CHM13v2.0
Eif4ebp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391061,268,276 - 61,288,448 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1061,264,270 - 61,288,440 (-)EnsemblGRCm39 Ensembl
GRCm381061,428,491 - 61,452,790 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,428,491 - 61,452,661 (-)EnsemblGRCm38mm10GRCm38
MGSCv371060,895,245 - 60,915,417 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361060,827,854 - 60,848,026 (-)NCBIMGSCv36mm8
Celera1062,533,926 - 62,553,995 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.21NCBI
Eif4ebp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82029,922,260 - 29,942,922 (-)NCBIGRCr8
mRatBN7.22029,379,444 - 29,400,110 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2029,382,668 - 29,399,946 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2030,395,410 - 30,416,078 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02029,781,661 - 29,802,329 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02030,524,161 - 30,544,821 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02031,055,292 - 31,072,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2031,055,789 - 31,072,469 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,841,624 - 32,858,081 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,562,634 - 29,579,209 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12029,577,608 - 29,592,890 (-)NCBI
Celera2030,812,166 - 30,828,643 (-)NCBICelera
Cytogenetic Map20q11NCBI
Eif4ebp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,844,750 - 20,879,885 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,844,750 - 20,879,874 (-)NCBIChiLan1.0ChiLan1.0
EIF4EBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,339,037 - 21,364,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,339,045 - 21,358,072 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,471,627 - 21,496,432 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0421,614,267 - 21,639,107 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl421,614,285 - 21,632,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1421,511,914 - 21,536,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0421,717,327 - 21,742,159 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0422,068,622 - 22,093,439 (+)NCBIUU_Cfam_GSD_1.0
Eif4ebp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721359,690,015 - 59,714,741 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365218,184,539 - 8,207,472 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365218,182,740 - 8,207,466 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF4EBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,323,642 - 73,349,291 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,323,609 - 73,355,443 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21479,241,168 - 79,266,886 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF4EBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1960,867,810 - 60,894,899 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl960,874,602 - 60,894,919 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604821,614,236 - 21,641,339 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif4ebp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247544,523,661 - 4,549,936 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247544,523,616 - 4,553,994 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034930751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000024226   ⟹   ENSPPAP00000005330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1069,406,745 - 69,423,249 (+)Ensembl
RefSeq Acc Id: XM_034930751   ⟹   XP_034786642
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2882,559,591 - 82,582,914 (+)NCBI
NHGRI_mPanPan11082,564,915 - 82,583,535 (+)NCBI
Mhudiblu_PPA_v01066,879,744 - 66,903,027 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034786642 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005330.1
RefSeq Acc Id: XP_034786642   ⟸   XM_034930751
- UniProtKB: A0A2R8ZMZ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000005330   ⟸   ENSPPAT00000024226


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000022070 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000024226.1 UniProtKB/TrEMBL
InterPro EIF4EBP UniProtKB/TrEMBL
NCBI Gene EIF4EBP2 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN UniProtKB/TrEMBL
  EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam eIF_4EBP UniProtKB/TrEMBL
UniProt A0A2R8ZMZ3 ENTREZGENE, UniProtKB/TrEMBL