CYP11B1 (cytochrome P450 family 11 subfamily B member 1) - Rat Genome Database

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Gene: CYP11B1 (cytochrome P450 family 11 subfamily B member 1) Pan paniscus
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Symbol: CYP11B1
Name: cytochrome P450 family 11 subfamily B member 1
RGD ID: 11986160
Description: ENCODES a protein that exhibits corticosterone 18-monooxygenase activity (ortholog); steroid 11-beta-monooxygenase activity (ortholog); INVOLVED IN aldosterone biosynthetic process (ortholog); C21-steroid hormone biosynthetic process (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH adrenal cortical adenoma (ortholog); Albuminuria (ortholog); Cardiomegaly (ortholog); FOUND IN dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytochrome P450 11B1, mitochondrial; cytochrome P450 11B1, mitochondrial-like; LOC100971586
RGD Orthologs
Human
Rat
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,309,139 - 160,316,623 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,835,342 - 135,842,827 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,584,976 - 139,592,466 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,628,706 - 142,634,654 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,629,127 - 142,634,654 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CYP11B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,309,139 - 160,316,623 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,835,342 - 135,842,827 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,584,976 - 139,592,466 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,628,706 - 142,634,654 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,629,127 - 142,634,654 (-)Ensemblpanpan1.1panPan2
CYP11B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388142,872,357 - 142,879,825 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8142,872,356 - 142,879,846 (-)EnsemblGRCh38hg38GRCh38
GRCh378143,953,773 - 143,961,241 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,950,775 - 143,958,238 (-)NCBINCBI36Build 36hg18NCBI36
Build 348143,952,217 - 143,958,238NCBI
Celera8140,263,402 - 140,270,865 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,206,042 - 139,213,505 (-)NCBIHuRef
CHM1_18143,994,059 - 144,001,520 (-)NCBICHM1_1
T2T-CHM13v2.08144,015,692 - 144,023,160 (-)NCBIT2T-CHM13v2.0
Cyp11b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,719,349 - 108,726,024 (-)NCBIGRCr8
mRatBN7.27106,838,590 - 106,845,004 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,838,590 - 106,845,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7108,564,515 - 108,570,947 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07110,788,181 - 110,794,613 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07110,734,122 - 110,740,554 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,248,759 - 116,255,205 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,156,219 - 116,255,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,151,128 - 116,157,542 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,043,365 - 113,049,779 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17113,077,595 - 113,084,003 (-)NCBI
Celera7103,210,977 - 103,217,398 (-)NCBICelera
Cytogenetic Map7q34NCBI
CYP11B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,125,409 - 137,132,267 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660392,814,491 - 2,820,047 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000012546   ⟹   ENSPPAP00000002643
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8142,629,127 - 142,634,654 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000012547   ⟹   ENSPPAP00000002644
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8142,629,127 - 142,634,654 (-)Ensembl
RefSeq Acc Id: XM_034967018   ⟹   XP_034822909
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27160,309,139 - 160,316,623 (-)NCBI
NHGRI_mPanPan18135,835,342 - 135,842,827 (-)NCBI
Mhudiblu_PPA_v08139,584,976 - 139,592,461 (-)NCBI
RefSeq Acc Id: XM_057303103   ⟹   XP_057159086
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27160,309,144 - 160,316,623 (-)NCBI
NHGRI_mPanPan18135,835,347 - 135,842,827 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034822909 (Get FASTA)   NCBI Sequence Viewer  
  XP_057159086 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000002643.1
  ENSPPAP00000002644.1
RefSeq Acc Id: XP_034822909   ⟸   XM_034967018
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZIZ0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000002644   ⟸   ENSPPAT00000012547
Ensembl Acc Id: ENSPPAP00000002643   ⟸   ENSPPAT00000012546
RefSeq Acc Id: XP_057159086   ⟸   XM_057303103
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZG45 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000011472 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000012546.1 UniProtKB/TrEMBL
  ENSPPAT00000012547.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro CYP11_CYP27_families UniProtKB/TrEMBL
  Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_mitochondrial UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
NCBI Gene LOC100971586 ENTREZGENE
PANTHER CYTOCHROME P450 11B1, MITOCHONDRIAL UniProtKB/TrEMBL
  CYTOCHROME P450 11B2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR24279 UniProtKB/TrEMBL
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  MITP450 UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A2R8ZG45 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZIZ0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:83046 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 CYP11B1  cytochrome P450 family 11 subfamily B member 1  LOC100971586  cytochrome P450 11B1, mitochondrial-like  Symbol and/or name change 5135510 APPROVED