HSPB6 (heat shock protein family B (small) member 6) - Rat Genome Database

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Gene: HSPB6 (heat shock protein family B (small) member 6) Pan paniscus
Analyze
Symbol: HSPB6
Name: heat shock protein family B (small) member 6
RGD ID: 11982549
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein kinase binding (ortholog); INVOLVED IN negative regulation of cardiac muscle cell apoptotic process (ortholog); ASSOCIATED WITH Brugada syndrome 5 (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); dystonia (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heat shock protein beta-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,748,846 - 41,752,205 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,734,174 - 43,737,533 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,684,355 - 32,686,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,418,655 - 41,421,012 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,419,608 - 41,420,972 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HSPB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,748,846 - 41,752,205 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,734,174 - 43,737,533 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,684,355 - 32,686,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,418,655 - 41,421,012 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,419,608 - 41,420,972 (-)Ensemblpanpan1.1panPan2
HSPB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,754,566 - 35,757,029 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,754,566 - 35,758,079 (-)EnsemblGRCh38hg38GRCh38
GRCh371936,245,467 - 36,247,930 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,937,310 - 40,939,770 (-)NCBINCBI36Build 36hg18NCBI36
Build 341940,937,309 - 40,939,770NCBI
Celera1932,958,948 - 32,961,408 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,750,462 - 32,752,811 (-)NCBIHuRef
CHM1_11936,246,780 - 36,249,243 (-)NCBICHM1_1
T2T-CHM13v2.01938,299,879 - 38,302,342 (-)NCBIT2T-CHM13v2.0
Hspb6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,251,961 - 30,254,868 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,251,603 - 30,254,868 (+)EnsemblGRCm39 Ensembl
GRCm38730,552,535 - 30,555,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,552,178 - 30,555,443 (+)EnsemblGRCm38mm10GRCm38
MGSCv37731,338,321 - 31,340,458 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,262,062 - 30,264,199 (+)NCBIMGSCv36mm8
Celera725,145,072 - 25,147,201 (+)NCBICelera
Cytogenetic Map7B1NCBI
cM Map718.56NCBI
Hspb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,934,372 - 94,936,516 (+)NCBIGRCr8
mRatBN7.2185,806,898 - 85,809,072 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,806,146 - 85,809,071 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,223,661 - 91,225,800 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,689,826 - 99,691,965 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0192,981,941 - 92,984,080 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,008,117 - 89,010,256 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,008,117 - 89,010,256 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,162,932 - 90,165,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,599,075 - 85,601,214 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1185,677,185 - 85,679,325 (+)NCBI
Celera180,178,449 - 80,180,588 (+)NCBICelera
Cytogenetic Map1q21NCBI
Hspb6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554682,797,076 - 2,800,546 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554682,797,076 - 2,799,589 (+)NCBIChiLan1.0ChiLan1.0
HSPB6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,878,370 - 116,880,852 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,878,396 - 116,879,943 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,283,627 - 116,286,116 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,481,343 - 117,483,832 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,481,362 - 117,483,467 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,044,719 - 117,047,208 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,668,337 - 116,670,826 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,723,717 - 117,726,206 (+)NCBIUU_Cfam_GSD_1.0
Hspb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,074,783 - 11,077,227 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570567,860 - 571,402 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936570568,708 - 571,099 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPB6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,181,443 - 45,183,998 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,181,439 - 45,184,011 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,636,893 - 40,639,463 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSPB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,664,355 - 30,666,841 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,665,315 - 30,666,802 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660738,455,715 - 8,458,214 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspb6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479410,060,732 - 10,063,903 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479410,060,728 - 10,063,800 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034945761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000055968   ⟹   ENSPPAP00000033098
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1941,419,608 - 41,420,972 (-)Ensembl
RefSeq Acc Id: XM_034945761   ⟹   XP_034801652
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22041,748,846 - 41,752,205 (-)NCBI
NHGRI_mPanPan11943,734,174 - 43,737,533 (-)NCBI
Mhudiblu_PPA_v01932,684,355 - 32,686,833 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034801652 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000033098.1
RefSeq Acc Id: XP_034801652   ⟸   XM_034945761
- UniProtKB: A0A2R9BTV1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000033098   ⟸   ENSPPAT00000055968
Protein Domains
Alpha-crystallin N-terminal   sHSP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039409 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000055968.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/TrEMBL
InterPro A-crystallin/Hsp20_dom UniProtKB/TrEMBL
  Alpha-crystallin/sHSP_animal UniProtKB/TrEMBL
  Alpha-crystallin_N UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/TrEMBL
NCBI Gene HSPB6 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN BETA-6 UniProtKB/TrEMBL
  PTHR45640 UniProtKB/TrEMBL
Pfam Crystallin UniProtKB/TrEMBL
  HSP20 UniProtKB/TrEMBL
PRINTS ACRYSTALLIN UniProtKB/TrEMBL
Superfamily-SCOP SSF49764 UniProtKB/TrEMBL
UniProt A0A2R9BTV1 ENTREZGENE, UniProtKB/TrEMBL