GPX5 (glutathione peroxidase 5) - Rat Genome Database

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Gene: GPX5 (glutathione peroxidase 5) Pan paniscus
Analyze
Symbol: GPX5
Name: glutathione peroxidase 5
RGD ID: 11981148
Description: ENCODES a protein that exhibits glutathione peroxidase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular response to oxidative stress (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); megacolon (ortholog); FOUND IN extracellular space (ortholog); sperm plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: epididymal secretory glutathione peroxidase; glutathione peroxidase 5 (epididymal androgen-related protein)
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2543,153,860 - 43,162,096 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,154,800 - 39,163,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0628,340,291 - 28,348,504 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,010,528 - 29,018,737 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,010,528 - 29,018,737 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GPX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2543,153,860 - 43,162,096 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,154,800 - 39,163,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0628,340,291 - 28,348,504 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,010,528 - 29,018,737 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,010,528 - 29,018,737 (+)Ensemblpanpan1.1panPan2
GPX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38628,525,881 - 28,534,955 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl628,525,881 - 28,534,955 (+)EnsemblGRCh38hg38GRCh38
GRCh37628,493,658 - 28,502,732 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36628,601,768 - 28,609,923 (+)NCBINCBI36Build 36hg18NCBI36
Build 34628,601,767 - 28,609,923NCBI
Celera630,100,218 - 30,109,121 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef628,300,120 - 28,309,014 (+)NCBIHuRef
CHM1_1628,496,188 - 28,505,099 (+)NCBICHM1_1
T2T-CHM13v2.0628,397,310 - 28,406,348 (+)NCBIT2T-CHM13v2.0
Gpx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,470,599 - 21,476,897 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,470,599 - 21,476,901 (-)EnsemblGRCm39 Ensembl
GRCm381321,286,429 - 21,292,727 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,286,429 - 21,292,731 (-)EnsemblGRCm38mm10GRCm38
MGSCv371321,378,298 - 21,384,555 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,293,898 - 21,300,151 (-)NCBIMGSCv36mm8
Celera1321,553,579 - 21,559,835 (-)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.73NCBI
Gpx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,131,853 - 48,138,801 (+)NCBIGRCr8
mRatBN7.21743,436,126 - 43,443,074 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,416,340 - 43,443,074 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1745,493,484 - 45,500,432 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01750,252,586 - 50,259,534 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01744,743,174 - 44,750,131 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01745,508,657 - 45,518,686 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1745,467,015 - 45,518,686 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01757,952,807 - 57,962,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11751,091,844 - 51,098,176 (+)NCBI
Celera1753,035,706 - 53,042,631 (-)NCBICelera
Cytogenetic Map17q11NCBI
GPX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13525,653,627 - 25,662,490 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3525,653,615 - 25,662,490 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3525,512,937 - 25,521,120 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03525,952,095 - 25,960,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3525,952,083 - 25,960,969 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13525,615,767 - 25,624,631 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03525,671,318 - 25,679,525 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,140,044 - 27,148,915 (+)NCBIUU_Cfam_GSD_1.0
Gpx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494628,952,020 - 28,961,691 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936914487,163 - 496,465 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,291,986 - 22,300,727 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,289,432 - 22,300,727 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,233,520 - 24,244,829 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11744,027,538 - 44,037,304 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1744,028,543 - 44,036,686 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604428,225,741 - 28,234,766 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003829704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000056501   ⟹   ENSPPAP00000033624
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl629,010,528 - 29,018,737 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056504   ⟹   ENSPPAP00000033628
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl629,010,528 - 29,016,952 (+)Ensembl
RefSeq Acc Id: XM_003829704   ⟹   XP_003829752
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2543,153,860 - 43,162,096 (+)NCBI
NHGRI_mPanPan1639,154,800 - 39,163,014 (+)NCBI
Mhudiblu_PPA_v0628,340,291 - 28,348,504 (+)NCBI
PanPan1.1629,010,528 - 29,018,737 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003829752 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000033624
  ENSPPAP00000033624.1
  ENSPPAP00000033628.1
RefSeq Acc Id: XP_003829752   ⟸   XM_003829704
- UniProtKB: A0A2R9C520 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000033624   ⟸   ENSPPAT00000056501
Ensembl Acc Id: ENSPPAP00000033628   ⟸   ENSPPAT00000056504


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039679 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056501 ENTREZGENE
  ENSPPAT00000056501.1 UniProtKB/TrEMBL
  ENSPPAT00000056504.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Glutathione_peroxidase UniProtKB/TrEMBL
  GPX_AS UniProtKB/TrEMBL
  GPX_CS UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene GPX5 ENTREZGENE
PANTHER EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE UniProtKB/TrEMBL
  PTHR11592 UniProtKB/TrEMBL
Pfam GSHPx UniProtKB/TrEMBL
PIRSF Glutathion_perox UniProtKB/TrEMBL
PRINTS GLUTPROXDASE UniProtKB/TrEMBL
PROSITE GLUTATHIONE_PEROXID_1 UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_2 UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_3 UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A2R9BVB9_PANPA UniProtKB/TrEMBL
  A0A2R9C520 ENTREZGENE, UniProtKB/TrEMBL