SMARCAL1 (SNF2 related chromatin remodeling annealing helicase 1) - Rat Genome Database

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Gene: SMARCAL1 (SNF2 related chromatin remodeling annealing helicase 1) Pan paniscus
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Symbol: SMARCAL1
Name: SNF2 related chromatin remodeling annealing helicase 1 (Ensembl:SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1)
RGD ID: 11943659
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA/DNA annealing activity (inferred); INVOLVED IN DNA damage response (inferred); DNA repair (inferred); double-strand break repair via nonhomologous end joining (inferred); ASSOCIATED WITH atrioventricular septal defect (ortholog); atypical hemolytic-uremic syndrome (ortholog); Dwarfism (ortholog); FOUND IN DNA replication factor A complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213119,040,341 - 119,111,253 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B119,055,327 - 119,126,253 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B103,672,934 - 103,743,802 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B222,276,294 - 222,347,258 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B222,276,353 - 222,347,258 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SMARCAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213119,040,341 - 119,111,253 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B119,055,327 - 119,126,253 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B103,672,934 - 103,743,802 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B222,276,294 - 222,347,258 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B222,276,353 - 222,347,258 (+)Ensemblpanpan1.1panPan2
SMARCAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382216,412,484 - 216,483,053 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2216,412,383 - 216,483,053 (+)EnsemblGRCh38hg38GRCh38
GRCh372217,277,207 - 217,347,776 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362216,986,820 - 217,056,021 (+)NCBINCBI36Build 36hg18NCBI36
Build 342217,104,083 - 217,173,278NCBI
Celera2211,045,111 - 211,115,648 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2209,131,595 - 209,202,094 (+)NCBIHuRef
CHM1_12217,282,680 - 217,353,309 (+)NCBICHM1_1
T2T-CHM13v2.02216,894,907 - 216,965,465 (+)NCBIT2T-CHM13v2.0
Smarcal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39172,575,593 - 72,675,949 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl172,622,410 - 72,672,293 (+)EnsemblGRCm39 Ensembl
GRCm38172,536,695 - 72,636,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl172,583,251 - 72,633,134 (+)EnsemblGRCm38mm10GRCm38
MGSCv37172,629,825 - 72,683,364 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36172,516,478 - 72,566,341 (+)NCBIMGSCv36mm8
Celera173,151,284 - 73,205,338 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map136.72NCBI
Smarcal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8981,689,446 - 81,735,406 (+)NCBIGRCr8
mRatBN7.2974,239,718 - 74,286,156 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl974,240,241 - 74,286,146 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx982,695,787 - 82,741,329 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0987,824,678 - 87,870,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0986,211,255 - 86,256,747 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0979,943,775 - 79,990,230 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl979,944,132 - 79,990,229 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0979,716,012 - 79,762,216 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4971,780,870 - 71,827,780 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1971,930,360 - 71,974,752 (+)NCBI
Celera971,834,400 - 71,880,797 (+)NCBICelera
Cytogenetic Map9q33NCBI
Smarcal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545316,719,931 - 16,784,709 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545316,724,286 - 16,784,129 (-)NCBIChiLan1.0ChiLan1.0
SMARCAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13723,364,941 - 23,425,206 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3723,367,220 - 23,419,248 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3724,193,550 - 24,253,982 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03723,392,255 - 23,452,837 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3723,392,945 - 23,447,926 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13723,277,174 - 23,331,540 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03723,229,412 - 23,289,770 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03723,247,796 - 23,308,267 (+)NCBIUU_Cfam_GSD_1.0
Smarcal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303171,702,084 - 171,797,210 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936586828,650 - 888,047 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936586828,661 - 887,988 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMARCAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15118,627,497 - 118,688,396 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115118,627,734 - 118,688,005 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215131,503,125 - 131,506,635 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMARCAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110102,253,187 - 102,319,356 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10102,255,453 - 102,319,330 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604097,083,733 - 97,149,570 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smarcal1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248238,644,826 - 8,706,591 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248238,645,340 - 8,708,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000062529   ⟹   ENSPPAP00000039618
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B222,276,353 - 222,347,258 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000062532   ⟹   ENSPPAP00000039621
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B222,278,585 - 222,347,183 (+)Ensembl
RefSeq Acc Id: XM_003818587   ⟹   XP_003818635
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213119,040,363 - 119,111,253 (+)NCBI
NHGRI_mPanPan12B119,055,327 - 119,126,253 (+)NCBI
Mhudiblu_PPA_v02B103,672,941 - 103,743,802 (+)NCBI
PanPan1.12B222,276,294 - 222,347,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003818588   ⟹   XP_003818636
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213119,040,405 - 119,111,253 (+)NCBI
NHGRI_mPanPan12B119,055,362 - 119,126,253 (+)NCBI
Mhudiblu_PPA_v02B103,673,249 - 103,743,802 (+)NCBI
PanPan1.12B222,276,628 - 222,347,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008971918   ⟹   XP_008970166
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213119,040,341 - 119,111,253 (+)NCBI
NHGRI_mPanPan12B119,055,329 - 119,126,245 (+)NCBI
Mhudiblu_PPA_v02B103,672,942 - 103,743,802 (+)NCBI
PanPan1.12B222,276,294 - 222,347,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008971919   ⟹   XP_008970167
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213119,040,363 - 119,111,253 (+)NCBI
NHGRI_mPanPan12B119,055,327 - 119,126,245 (+)NCBI
Mhudiblu_PPA_v02B103,672,941 - 103,743,802 (+)NCBI
PanPan1.12B222,276,353 - 222,347,258 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004670316
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213119,040,391 - 119,106,474 (+)NCBI
NHGRI_mPanPan12B119,055,347 - 119,121,437 (+)NCBI
Mhudiblu_PPA_v02B103,672,934 - 103,739,022 (+)NCBI
RefSeq Acc Id: XP_003818635   ⟸   XM_003818587
- UniProtKB: A0A2R9CF28 (UniProtKB/TrEMBL),   A0A2R9CCG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008970166   ⟸   XM_008971918
- UniProtKB: A0A2R9CF28 (UniProtKB/TrEMBL),   A0A2R9CCG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008970167   ⟸   XM_008971919
- UniProtKB: A0A2R9CF28 (UniProtKB/TrEMBL),   A0A2R9CCG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003818636   ⟸   XM_003818588
- UniProtKB: A0A2R9CF28 (UniProtKB/TrEMBL),   A0A2R9CCG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000039618   ⟸   ENSPPAT00000062529
Ensembl Acc Id: ENSPPAP00000039621   ⟸   ENSPPAT00000062532

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042500 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062529.1 UniProtKB/TrEMBL
  ENSPPAT00000062532.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro HARP_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
KEGG Report pps:100971581 UniProtKB/TrEMBL
NCBI Gene SMARCAL1 ENTREZGENE
PANTHER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER UniProtKB/TrEMBL
  PTHR45766:SF3 UniProtKB/TrEMBL
Pfam HARP UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
PROSITE HARP UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9CCG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CF28 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-25 SMARCAL1  SNF2 related chromatin remodeling annealing helicase 1  SMARCAL1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1  Symbol and/or name change 5135510 APPROVED