ABHD2 (abhydrolase domain containing 2, acylglycerol lipase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: ABHD2 (abhydrolase domain containing 2, acylglycerol lipase) Pan paniscus
Analyze
Symbol: ABHD2
Name: abhydrolase domain containing 2, acylglycerol lipase
RGD ID: 11921360
Description: ENCODES a protein that exhibits acetylesterase activity (inferred); carboxylic ester hydrolase activity (inferred); diacylglycerol lipase activity (inferred); INVOLVED IN negative regulation of smooth muscle cell migration (ortholog); response to wounding (ortholog); smooth muscle cell migration (ortholog); ASSOCIATED WITH amenorrhea (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN acrosomal vesicle (inferred); membrane (inferred); sperm flagellum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: abhydrolase domain containing 2; abhydrolase domain-containing protein 2; monoacylglycerol lipase ABHD2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,780,453 - 67,891,454 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11586,987,070 - 87,095,823 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1586,987,070 - 87,095,818 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ABHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,780,453 - 67,891,454 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11586,987,070 - 87,095,823 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1586,987,070 - 87,095,818 (+)Ensemblpanpan1.1panPan2
ABHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,040,998 - 89,202,355 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,087,459 - 89,202,355 (+)EnsemblGRCh38hg38GRCh38
GRCh371589,584,229 - 89,745,586 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361587,432,429 - 87,546,591 (+)NCBINCBI36Build 36hg18NCBI36
Build 341587,432,627 - 87,541,199NCBI
Celera1566,032,695 - 66,146,881 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1565,743,212 - 65,857,546 (+)NCBIHuRef
CHM1_11589,472,357 - 89,586,578 (+)NCBICHM1_1
T2T-CHM13v2.01586,795,895 - 86,957,178 (+)NCBIT2T-CHM13v2.0
Abhd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39778,923,002 - 79,015,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl778,922,947 - 79,015,256 (+)EnsemblGRCm39 Ensembl
GRCm38779,273,266 - 79,361,601 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,273,199 - 79,365,508 (+)EnsemblGRCm38mm10GRCm38
MGSCv37786,418,152 - 86,506,487 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,146,779 - 79,235,114 (+)NCBIMGSCv36mm8
Celera776,673,721 - 76,758,716 (+)NCBICelera
Cytogenetic Map7D2NCBI
cM Map744.96NCBI
Abhd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,626,748 - 142,707,892 (+)NCBIGRCr8
mRatBN7.21133,217,403 - 133,298,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,217,375 - 133,299,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,126,872 - 141,207,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,296,304 - 148,377,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,213,989 - 141,294,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01140,998,240 - 141,087,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1140,998,240 - 141,087,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,965,576 - 142,049,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,025,144 - 135,111,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,103,531 - 135,191,046 (+)NCBI
Celera1125,281,300 - 125,361,782 (+)NCBICelera
Cytogenetic Map1q31NCBI
Abhd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,884,624 - 15,983,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,878,972 - 15,983,322 (-)NCBIChiLan1.0ChiLan1.0
ABHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,151,500 - 52,255,024 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,151,535 - 52,249,612 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,787,785 - 54,891,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,570,316 - 52,673,869 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,570,371 - 52,673,867 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,092,905 - 52,196,309 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,303,690 - 52,406,947 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,642,383 - 52,745,916 (+)NCBIUU_Cfam_GSD_1.0
Abhd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640131,254,659 - 131,360,435 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648314,974,035 - 15,074,154 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648314,974,053 - 15,079,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl754,655,804 - 54,770,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1754,655,694 - 54,776,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2759,630,969 - 59,746,589 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,631,436 - 7,742,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,631,412 - 7,740,394 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605939,085,426 - 39,196,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476816,297,464 - 16,402,624 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476816,283,369 - 16,404,476 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000063993   ⟹   ENSPPAP00000041072
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1586,987,070 - 87,095,818 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000063996   ⟹   ENSPPAP00000041075
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1587,013,427 - 87,094,279 (+)Ensembl
RefSeq Acc Id: XM_003820419   ⟹   XP_003820467
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
Mhudiblu_PPA_v01567,780,453 - 67,891,154 (+)NCBI
PanPan1.11586,987,070 - 87,095,823 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973870   ⟹   XP_008972118
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
Mhudiblu_PPA_v01567,780,476 - 67,891,154 (+)NCBI
PanPan1.11586,987,321 - 87,094,601 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055098946   ⟹   XP_054954921
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
RefSeq Acc Id: XM_055098947   ⟹   XP_054954922
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
RefSeq Acc Id: XM_055098948   ⟹   XP_054954923
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
RefSeq Acc Id: XM_055098949   ⟹   XP_054954924
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
RefSeq Acc Id: XM_055098950   ⟹   XP_054954925
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBI
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBI
RefSeq Acc Id: XP_003820467   ⟸   XM_003820419
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL),   A0A2R9CGJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008972118   ⟸   XM_008973870
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL),   A0A2R9CGJ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000041075   ⟸   ENSPPAT00000063996
Ensembl Acc Id: ENSPPAP00000041072   ⟸   ENSPPAT00000063993
RefSeq Acc Id: XP_054954925   ⟸   XM_055098950
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054954923   ⟸   XM_055098948
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054954921   ⟸   XM_055098946
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054954924   ⟸   XM_055098949
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054954922   ⟸   XM_055098947
- UniProtKB: A0A2R9CQN6 (UniProtKB/TrEMBL)
Protein Domains
AB hydrolase-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043154 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063993.1 UniProtKB/TrEMBL
  ENSPPAT00000063996.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  AB_hydrolase_4_CS UniProtKB/TrEMBL
  AB_hydrolase_4_sf UniProtKB/TrEMBL
  ABHD4 UniProtKB/TrEMBL
KEGG Report pps:100971480 UniProtKB/TrEMBL
NCBI Gene ABHD2 ENTREZGENE
PANTHER ABHYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MONOACYLGLYCEROL LIPASE ABHD2 UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PIRSF Ab_hydro_YheT UniProtKB/TrEMBL
PROSITE UPF0017 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9CGJ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CQN6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-28 ABHD2  abhydrolase domain containing 2, acylglycerol lipase  ABHD2  abhydrolase domain containing 2  Symbol and/or name change 5135510 APPROVED