UCHL5 (ubiquitin C-terminal hydrolase L5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: UCHL5 (ubiquitin C-terminal hydrolase L5) Pan paniscus
Analyze
Symbol: UCHL5
Name: ubiquitin C-terminal hydrolase L5
RGD ID: 11904828
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN chromatin remodeling (inferred); forebrain morphogenesis (inferred); lateral ventricle development (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); Experimental Diabetes Mellitus (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytosolic proteasome complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase isozyme L5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,396,699 - 56,444,658 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,471,501 - 168,519,366 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,764,606 - 172,812,502 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,764,606 - 172,811,880 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UCHL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,396,699 - 56,444,658 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,471,501 - 168,519,366 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,764,606 - 172,812,502 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,764,606 - 172,811,880 (-)Ensemblpanpan1.1panPan2
UCHL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381193,012,254 - 193,060,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1193,012,250 - 193,060,080 (-)EnsemblGRCh38hg38GRCh38
GRCh371192,981,384 - 193,029,206 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,251,522 - 191,295,144 (-)NCBINCBI36Build 36hg18NCBI36
Build 341189,716,556 - 189,760,178NCBI
Celera1166,094,514 - 166,138,132 (-)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1164,217,286 - 164,265,038 (-)NCBIHuRef
CHM1_11194,403,215 - 194,450,956 (-)NCBICHM1_1
T2T-CHM13v2.01192,359,462 - 192,407,284 (-)NCBIT2T-CHM13v2.0
Uchl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,652,993 - 143,683,204 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1143,653,010 - 143,683,204 (+)EnsemblGRCm39 Ensembl
GRCm381143,777,234 - 143,807,466 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,777,272 - 143,807,466 (+)EnsemblGRCm38mm10GRCm38
MGSCv371145,624,408 - 145,654,596 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361145,539,553 - 145,569,033 (+)NCBIMGSCv36mm8
Celera1146,352,307 - 146,382,478 (+)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.54NCBI
Uchl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81358,070,947 - 58,106,825 (+)NCBIGRCr8
mRatBN7.21355,520,722 - 55,556,503 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1355,520,729 - 55,556,502 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1358,089,283 - 58,125,040 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01359,356,425 - 59,392,187 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01356,641,812 - 56,677,555 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01360,568,102 - 60,603,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,545,635 - 60,603,811 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,556,665 - 65,592,649 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,605,912 - 57,643,050 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11357,619,991 - 57,908,156 (+)NCBI
Celera1355,608,483 - 55,644,135 (+)NCBICelera
Cytogenetic Map13q21NCBI
Uchl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540630,432,652 - 30,468,741 (-)NCBIChiLan1.0ChiLan1.0
UCHL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1386,004,595 - 6,045,999 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl386,004,659 - 6,113,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,102,225 - 6,143,345 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0386,021,866 - 6,063,304 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl386,021,819 - 6,125,039 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1386,021,177 - 6,062,576 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0386,386,756 - 6,427,852 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0386,615,571 - 6,657,212 (+)NCBIUU_Cfam_GSD_1.0
Uchl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934480,855,144 - 80,907,329 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366381,242,893 - 1,290,512 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366381,242,950 - 1,289,376 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCHL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl10725,561 - 763,985 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.110725,688 - 761,633 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,258,893 - 2,274,919 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UCHL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,362,340 - 36,415,550 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2536,364,027 - 36,414,762 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605537,311,867 - 37,365,433 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uchl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624814529,084 - 567,666 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624814529,100 - 568,387 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000034903   ⟹   ENSPPAP00000012241
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1172,764,606 - 172,811,880 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000034912   ⟹   ENSPPAP00000012250
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1172,764,606 - 172,811,880 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000034917   ⟹   ENSPPAP00000012255
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1172,768,521 - 172,811,696 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000034921   ⟹   ENSPPAP00000012259
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1172,770,987 - 172,811,660 (-)Ensembl
RefSeq Acc Id: XM_003820596   ⟹   XP_003820644
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,233 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,744 (-)NCBI
PanPan1.11172,764,606 - 172,811,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008974037   ⟹   XP_008972285
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,277 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,746 (-)NCBI
PanPan1.11172,764,606 - 172,811,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008974040   ⟹   XP_008972288
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,278 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,746 (-)NCBI
PanPan1.11172,764,606 - 172,811,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024928298   ⟹   XP_024784066
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,273 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,746 (-)NCBI
PanPan1.11172,764,606 - 172,811,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024928299   ⟹   XP_024784067
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,187 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,746 (-)NCBI
PanPan1.11172,764,606 - 172,811,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034942831   ⟹   XP_034798722
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,262 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,750 (-)NCBI
RefSeq Acc Id: XM_034942835   ⟹   XP_034798726
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2156,732,736 - 56,780,775 (+)NCBI
NHGRI_mPanPan1156,397,267 - 56,444,658 (+)NCBI
Mhudiblu_PPA_v01168,471,501 - 168,518,748 (-)NCBI
RefSeq Acc Id: XP_008972285   ⟸   XM_008974037
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008972288   ⟸   XM_008974040
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_003820644   ⟸   XM_003820596
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_024784067   ⟸   XM_024928299
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_024784066   ⟸   XM_024928298
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034798722   ⟸   XM_034942831
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034798726   ⟸   XM_034942835
- Peptide Label: isoform X4
Ensembl Acc Id: ENSPPAP00000012250   ⟸   ENSPPAT00000034912
Ensembl Acc Id: ENSPPAP00000012241   ⟸   ENSPPAT00000034903
Ensembl Acc Id: ENSPPAP00000012259   ⟸   ENSPPAT00000034921
Ensembl Acc Id: ENSPPAP00000012255   ⟸   ENSPPAT00000034917

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029294 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034903.1 UniProtKB/TrEMBL
  ENSPPAT00000034912.1 UniProtKB/TrEMBL
  ENSPPAT00000034917.1 UniProtKB/TrEMBL
  ENSPPAT00000034921.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.860 UniProtKB/TrEMBL
  3.40.532.10 UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C12_UCH UniProtKB/TrEMBL
  Peptidase_C12_UCH_sf UniProtKB/TrEMBL
  Ubiquitinyl_hydrolase_UCH37 UniProtKB/TrEMBL
  UCH37 UniProtKB/TrEMBL
  UCH_C UniProtKB/TrEMBL
NCBI Gene UCHL5 ENTREZGENE
PANTHER PTHR10589 UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 UniProtKB/TrEMBL
Pfam Peptidase_C12 UniProtKB/TrEMBL
  UCH_C UniProtKB/TrEMBL
PIRSF Ubiquitinyl_hydrolase_UCH37 UniProtKB/TrEMBL
PRINTS UBCTHYDRLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A2R9A5U2_PANPA UniProtKB/TrEMBL
  A0A2R9A9C4_PANPA UniProtKB/TrEMBL
  A0A2R9A9D0_PANPA UniProtKB/TrEMBL
  A0A2R9A9X9_PANPA UniProtKB/TrEMBL