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Gene: LMAN1L (lectin, mannose binding 1 like) Pan paniscus

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Symbol:

LMAN1L

Name:

lectin, mannose binding 1 like

RGD ID:

11900765

Description:

ENCODES a protein that exhibits carbohydrate binding (inferred); D-mannose binding (inferred); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN COPII-coated ER to Golgi transport vesicle (inferred); endomembrane system (inferred); endoplasmic reticulum membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

protein ERGIC-53-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	64,031,080 - 64,053,518 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	68,203,464 - 68,217,188 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	53,754,682 - 53,768,324 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	73,373,160 - 73,386,050 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	73,373,160 - 73,386,050 (+)	Ensembl			panPan2	panpan1.1

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

prostate cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum to Golgi vesicle-mediated transport (IEA)

Cellular Component

COPII-coated ER to Golgi transport vesicle (IEA)

endomembrane system (IEA)

endoplasmic reticulum membrane (IEA)

endoplasmic reticulum-Golgi intermediate compartment (IEA)

endoplasmic reticulum-Golgi intermediate compartment membrane (IEA)

Golgi membrane (IEA)

membrane (IEA)

Molecular Function

carbohydrate binding (IEA)

D-mannose binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

LMAN1L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	64,031,080 - 64,053,518 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	68,203,464 - 68,217,188 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	53,754,682 - 53,768,324 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	73,373,160 - 73,386,050 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	73,373,160 - 73,386,050 (+)	Ensembl			panPan2	panpan1.1

LMAN1L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	74,812,835 - 74,825,754 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	74,812,716 - 74,825,757 (+)	Ensembl			hg38	GRCh38
GRCh37	15	75,105,176 - 75,118,095 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	72,892,247 - 72,905,152 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	72,892,243 - 72,905,148	NCBI
Celera	15	52,055,222 - 52,068,128 (+)	NCBI		Celera
Cytogenetic Map	15	q24.1	NCBI
HuRef	15	51,902,237 - 51,915,133 (+)	NCBI		HuRef
CHM1_1	15	75,223,678 - 75,236,784 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	72,682,728 - 72,695,650 (+)	NCBI		T2T-CHM13v2.0

Lman1l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	57,514,080 - 57,528,057 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	57,514,368 - 57,528,057 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	57,607,033 - 57,620,774 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	57,607,085 - 57,620,774 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	57,454,840 - 57,468,581 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	57,405,170 - 57,418,898 (-)	NCBI		MGSCv36	mm8
Celera	9	54,842,853 - 54,856,695 (-)	NCBI		Celera
Cytogenetic Map	9	B	NCBI
cM Map	9	31.13	NCBI

Lman1l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	66,906,684 - 66,925,512 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	66,906,624 - 66,919,584 (-)	Ensembl				GRCr8
mRatBN7.2	8	58,010,839 - 58,029,599 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	58,010,839 - 58,023,681 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	63,543,636 - 63,556,507 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	61,821,213 - 61,834,082 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	59,685,760 - 59,698,629 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	62,386,806 - 62,400,370 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	62,386,806 - 62,399,648 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	62,164,008 - 62,177,928 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	61,361,481 - 61,375,270 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	57,476,759 - 57,489,601 (-)	NCBI		Celera
RGSC_v3.1	8	61,380,534 - 61,394,324 (-)	NCBI
Cytogenetic Map	8	q24	NCBI

Lman1l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	3,110,952 - 3,123,131 (-)	Ensembl
ChiLan1.0	NW_004955450	3,111,004 - 3,123,266 (-)	NCBI	ChiLan1.0	ChiLan1.0

LMAN1L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	37,875,499 - 37,888,428 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	37,875,691 - 37,888,824 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	37,807,529 - 37,819,955 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	38,079,957 - 38,092,386 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	38,079,829 - 38,092,264 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	38,032,726 - 38,045,144 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	38,079,049 - 38,091,473 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	38,314,543 - 38,326,975 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lman1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	115,936,917 - 115,949,663 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	33,785,748 - 33,797,575 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	33,785,650 - 33,797,726 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LMAN1L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	58,717,821 - 58,730,172 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	58,717,159 - 58,730,752 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	63,406,414 - 63,419,241 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LMAN1L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	8,645,361 - 8,659,139 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	8,646,256 - 8,658,576 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	132,972,104 - 132,985,321 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lman1l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624894	33,158 - 44,500 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624894	33,158 - 45,250 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Lman1l
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	51,496,990 - 51,509,768 (-)	NCBI		Rrattus_CSIRO_v1

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003811094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003811095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000045090 ⟹ ENSPPAP00000022282

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	73,373,160 - 73,386,050 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000045094 ⟹ ENSPPAP00000022286

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	73,373,163 - 73,386,050 (+)	Ensembl

RefSeq Acc Id:

XM_003811094 ⟹ XP_003811142

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	64,031,080 - 64,053,518 (+)	NCBI
NHGRI_mPanPan1	15	68,203,464 - 68,217,188 (+)	NCBI
Mhudiblu_PPA_v0	15	53,754,682 - 53,768,320 (+)	NCBI
PanPan1.1	15	73,373,160 - 73,386,050 (+)	NCBI

Sequence:

show sequence

TCACGATGCCAGCGGTCAGTGGTCCAGGTCCCTTGTTCTGCCTTCTCCTCCTGCTCCTGGACCC
CCACAGCCCTGAGACGGGGTGTCCTCCTCTACGCAGGTTTGAGTACAAGCTCAGCTTCAAAGGC
CCAAGGCTGGCATTGCCTGGGGCTGGAATACCCTTCTGGAGCCATCATGGAGACGCCATCCTGG
GCCTGGAGGAAGTGCGGCTGACGCCATCCATGAGGAACCGGAGTGGCGCCGTGTGGAGCAGGGC
CTCTGTCCCCTTCTCTGCCTGGGAAGTAGAGGTGCAGATGAGGGTGACGGGACTGGGGCGCCGG
GGAGCCCAGGGCATGGCCCTGTGGTACACCCGGGGCAGGGGCCATGTAGGCTCTGTCCTTGGGG
GGCTGGCCTCGTGGGACGGCATCGGGATCTTCTTTGACTCTCTGGCAGAGGATACTCAGGACAG
TCCTGCCATCCGTGTGCTGGCCAGCGACGGGCACATCCCCTCTGAGCAGCCTGGGGATGGAGCT
AGCCAAGTGCTGGGCTCCTGTCATTGGGACTTCCGGAACCGGCCACACCCCTTCAGAGCACGGA
TCACCTACTGGGGGCAGAGGCTGCGCGTGTCCTTGAACAGTGGCCTCACTCCCAGTGATCCAGA
TGAGTTCTGTGTGGATGTGGGGCCCCTGCTTTTGGTCCCTGGAGGCTTCTTTGGGGTCTCAGCA
GCCACTGGCACCCTGGCAGATGATCATGATGTCCTGTCCTTCCTGACCTTCAGCTTGAGTGAGC
CCAGCCCAGAGGTTCCCCCTCAGCCCTTCCTGGAGATGCAGCAGCTCCGCCTGGCGAGGCAGCT
GGAAGGGCTGCGGGCAAGGCTGGGCTTGGGCACCAGGGAGGATGTAACTCCAAAGTCAGACTCT
GAAGCTCAAGGAGAAGGGGAAAGGCTCTTCGACCTGGAGGAGACACTGGGCAGACACCGTGGGA
TCCTGCAGGCTCTGTGGGGTCTCTCCAAGCAGCTGGCCCAGGCTGAGAGACAATGGAAGAAGCA
GCTGGGGCCCCTAGGCCAAGCCAGGCCTGACGGAGGCTGGGCCCTGGATGCTTCCTGCCAGATT
CCATCCACCCCAGGGAGGGGTGGCCACCTCTCCATGTCACTCAATAAGGACTCTGCCAAGGTCG
GTGCCCTGCTCCATGGACAGTGGACTCTGCTCCAGGCCCTGCAAGAGATGAGGGATGCAGCTGT
CCGCATGGCTGCAGAAGCCCAGGTCTCCTACCTGCCTGTGGGCACTGAGCATCATTTCTTAGAG
CTGGACCACATCCTGGGCCTCCTGCAGGAGGAGCTTCGGGGCCCGGCGAAGGCAGTGGCCAAGG
CCCCCCGCCCACCTGGCCAGCCCCCAAGGGCTTCCTCGTGCCTGCAGCCTGGCATCTTCCTGTT
CTACCTCCTCATTCAGACTGTAGGCTTCTTCGGCTACGTGCACTTCAGGCAGGAGCTGAACAAG
AGCCTTCAGGAGTGTCTGTCCACAGGCAGCCTTCCTCTGGATCCTGCACCACACACCCCCAGGG
CCCCGGGGATTCTGAGGAGGCAGCCTCTCCCTGCCAGCATGCCTGCCTGACCCACCTCAGAGCC
TGCTTTGCATCACTGGGAAGCAGGCAGTGTCTTGGGTGGGGGCTTGGTCAGTATCCTCTCCGTC
TGGGTGCCCAGCTCCCACGCACACCTGAGCTTTCGGCATGCTCCCACCTCGTTAAAGGTGATTT
CCCTCTCCCCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003811142	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000022282.1
	ENSPPAP00000022286.1
	ENSPPAP00050043305

RefSeq Acc Id:

XP_003811142 ⟸ XM_003811094

- UniProtKB:

A0A2R9B2A4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPAVSGPGPLFCLLLLLLDPHSPETGCPPLRRFEYKLSFKGPRLALPGAGIPFWSHHGDAILGL
EEVRLTPSMRNRSGAVWSRASVPFSAWEVEVQMRVTGLGRRGAQGMALWYTRGRGHVGSVLGGL
ASWDGIGIFFDSLAEDTQDSPAIRVLASDGHIPSEQPGDGASQVLGSCHWDFRNRPHPFRARIT
YWGQRLRVSLNSGLTPSDPDEFCVDVGPLLLVPGGFFGVSAATGTLADDHDVLSFLTFSLSEPS
PEVPPQPFLEMQQLRLARQLEGLRARLGLGTREDVTPKSDSEAQGEGERLFDLEETLGRHRGIL
QALWGLSKQLAQAERQWKKQLGPLGQARPDGGWALDASCQIPSTPGRGGHLSMSLNKDSAKVGA
LLHGQWTLLQALQEMRDAAVRMAAEAQVSYLPVGTEHHFLELDHILGLLQEELRGPAKAVAKAP
RPPGQPPRASSCLQPGIFLFYLLIQTVGFFGYVHFRQELNKSLQECLSTGSLPLDPAPHTPRAP
GILRRQPLPASMPA

hide sequence

Ensembl Acc Id:

ENSPPAP00000022282 ⟸ ENSPPAT00000045090

Ensembl Acc Id:

ENSPPAP00000022286 ⟸ ENSPPAT00000045094

Protein Domains

L-type lectin-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034334	Ensembl, UniProtKB/TrEMBL
	ENSPPAG00050030624	ENTREZGENE
Ensembl Transcript	ENSPPAT00000045090.1	UniProtKB/TrEMBL
	ENSPPAT00000045094.1	UniProtKB/TrEMBL
	ENSPPAT00050065681	ENTREZGENE
Gene3D-CATH	2.60.120.200	UniProtKB/TrEMBL
InterPro	ConA-like_dom_sf	UniProtKB/TrEMBL
	Intracellular_Lectin-GPT	UniProtKB/TrEMBL
	Lectin_leg	UniProtKB/TrEMBL
KEGG Report	pps:100974510	UniProtKB/TrEMBL
NCBI Gene	LMAN1L	ENTREZGENE
PANTHER	PROTEIN ERGIC-53-LIKE	UniProtKB/TrEMBL
	VESICULAR MANNOSE-BINDING LECTIN	UniProtKB/TrEMBL
Pfam	Lectin_leg-like	UniProtKB/TrEMBL
PROSITE	L_LECTIN_LIKE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49899	UniProtKB/TrEMBL
UniProt	A0A2R9B2A4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B4D6_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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