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Gene: CYFIP1 (cytoplasmic FMR1 interacting protein 1) Pan paniscus

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Symbol:

CYFIP1

Name:

cytoplasmic FMR1 interacting protein 1

RGD ID:

11892870

Description:

ENCODES a protein that exhibits RNA 7-methylguanosine cap binding (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); lamellipodium assembly (ortholog); negative regulation of synaptic vesicle recycling (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; ASSOCIATED WITH Angelman syndrome (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN axonal growth cone (ortholog); central region of growth cone (ortholog); dendritic growth cone (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cytoplasmic FMR1-interacting protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	12,204,434 - 12,315,794 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	15,928,676 - 16,042,452 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	15	20,462,755 - 20,573,684 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	20,462,811 - 20,573,684 (+)	Ensembl	panpan1.1		panPan2

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Angelman syndrome (ISO)

autism spectrum disorder (ISO)

autistic disorder (ISO)

chromosome 15q11.2 deletion syndrome (ISO)

COVID-19 (ISO)

fragile X syndrome (ISO)

hereditary spastic paraplegia 6 (ISO)

intellectual disability (ISO)

Neurodevelopmental Disorders (ISO)

Schaaf-Yang syndrome (ISO)

schizophrenia (ISO)

temporal lobe epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon extension (IEA)

cellular response to insulin stimulus (ISO)

cognition (IEA)

dendrite extension (IEA)

lamellipodium assembly (IEA,ISO)

negative regulation of synaptic vesicle recycling (ISO)

negative regulation of translation (IEA)

neuron projection development (IEA)

positive regulation of Arp2/3 complex-mediated actin nucleation (IEA)

positive regulation of axon extension (ISO)

positive regulation of axonogenesis (ISO)

positive regulation of dendrite development (ISO)

positive regulation of lamellipodium assembly (IEA)

positive regulation of neurotrophin TRK receptor signaling pathway (IEA)

positive regulation of ruffle assembly (ISO)

Rac protein signal transduction (IEA)

regulation of actin filament polymerization (IEA)

regulation of modification of postsynaptic actin cytoskeleton (IEA)

regulation of myelination (ISO)

regulation of translation at postsynapse, modulating synaptic transmission (IEA)

response to electrical stimulus (ISO)

Cellular Component

axonal growth cone (ISO)

cell leading edge (IEA)

central region of growth cone (ISO)

cytoplasm (IEA)

dendritic growth cone (ISO)

dendritic spine (ISO)

excitatory synapse (ISO)

filopodium tip (ISO)

lamellipodium (IEA)

neuron projection (IEA)

neuronal cell body (ISO)

perinuclear region of cytoplasm (IEA)

peripheral region of growth cone (ISO)

postsynapse (IEA,ISO)

SCAR complex (IEA)

synapse (IEA)

terminal bouton (ISO)

Molecular Function

protein binding (ISO)

RNA 7-methylguanosine cap binding (ISO)

small GTPase binding (IEA,ISO)

translation repressor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

Rho/Rac/Cdc42 mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CYFIP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	12,204,434 - 12,315,794 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	15,928,676 - 16,042,452 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	15	20,462,755 - 20,573,684 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	20,462,811 - 20,573,684 (+)	Ensembl	panpan1.1		panPan2

CYFIP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	22,867,052 - 22,980,898 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	22,867,052 - 22,981,063 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	22,892,170 - 23,006,016 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	20,444,125 - 20,555,044 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	20,444,124 - 20,555,043	NCBI
Celera	15	1,376,209 - 1,487,232 (-)	NCBI		Celera
Cytogenetic Map	15	q11.2	NCBI
HuRef	15	1,205,387 - 1,315,987 (+)	NCBI		HuRef
CHM1_1	15	22,841,725 - 22,952,892 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	20,538,904 - 20,652,761 (-)	NCBI		T2T-CHM13v2.0

Cyfip1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	55,491,556 - 55,582,381 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	55,491,493 - 55,582,350 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	55,842,022 - 55,932,633 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	55,841,745 - 55,932,602 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	63,097,441 - 63,188,003 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	55,739,875 - 55,798,505 (+)	NCBI		MGSCv36	mm8
Celera	7	53,195,732 - 53,286,248 (+)	NCBI		Celera
Cytogenetic Map	7	B5	NCBI
cM Map	7	33.42	NCBI

Cyfip1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	115,842,754 - 115,935,163 (+)	NCBI		GRCr8
mRatBN7.2	1	106,710,924 - 106,799,393 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	106,711,016 - 106,799,386 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	112,100,298 - 112,189,006 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	120,572,167 - 120,660,875 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	113,821,095 - 113,909,828 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	114,258,773 - 114,347,138 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	114,258,719 - 114,347,137 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	115,265,128 - 115,353,515 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	107,245,993 - 107,334,337 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	107,324,324 - 107,412,679 (+)	NCBI
Celera	1	100,921,447 - 101,009,775 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

CYFIP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	32,096,471 - 32,170,107 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	32,097,037 - 32,187,781 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	34,509,239 - 34,585,945 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	32,162,887 - 32,239,605 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	32,117,281 - 32,240,269 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	31,650,943 - 31,773,999 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	31,945,859 - 32,022,546 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	32,056,552 - 32,133,289 (+)	NCBI		UU_Cfam_GSD_1.0

Cyfip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	120,416,388 - 120,482,622 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	38,267,703 - 38,332,218 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	38,264,455 - 38,331,995 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYFIP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	32,064,428 - 32,175,094 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	32,064,431 - 32,175,095 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

CYFIP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	53,562,105 - 53,673,544 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	53,595,767 - 53,672,977 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	36,289,010 - 36,405,036 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cyfip1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624896	2,723,462 - 2,800,113 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624896	2,726,622 - 2,774,671 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003805941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008976968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034951848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034951850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000031182 ⟹ ENSPPAP00000008546

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	20,462,811 - 20,573,684 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000031188 ⟹ ENSPPAP00000008552

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	20,496,077 - 20,573,122 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000031189 ⟹ ENSPPAP00000008553

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	20,496,077 - 20,506,878 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000031190 ⟹ ENSPPAP00000008554

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	20,496,077 - 20,496,548 (+)	Ensembl

RefSeq Acc Id:

XM_003805941 ⟹ XP_003805989

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	12,204,434 - 12,315,221 (-)	NCBI
NHGRI_mPanPan1	15	15,928,676 - 16,041,879 (-)	NCBI
PanPan1.1	15	20,462,755 - 20,573,684 (+)	NCBI

Sequence:

show sequence

GGAGCGCCGGGAGGAAGAGGCCGAGCCGGGAGAGCCCCCGCCCCGGGAGGAAGGGGAGGAGGCC
GAGTGTTTCCTGGCGCATTCCCGGCCAGCCCGAGTGACTCACTCGGCCAAGGAAACTCCCAGGG
CCCGCCCAGGACCCCCAAGCCGCCGCGGACGCAGCCCAGGATGGCGGCCCAGGTGACTCTGGAG
GACGCGCTGTCCAACGTGGACCTCCTAGAGGAGCTGCCCCTGCCCGACCAGCAGCCCTGCATCG
AGCCCCCGCCATCCTCGCTGCTCTACCAGCCAAATTTCAACACTAACTTTGAAGACAGAAATGC
ATTTGTTACTGGCATCGCAAGATACATCGAACAAGCCACCGTCCACTCTAGCATGAACGAGATG
CTGGAGGAGGGCCAAGAATATGCTGTCATGCTGTACACCTGGAGGAGCTGCTCCCGGGCCATCC
CACAGGTGAAATGTAACGAGCAGCCTAACAGAGTGGAAATCTACGAGAAAACCGTGGAGGTTCT
GGAGCCTGAGGTCACAAAACTGATGAATTTCATGTACTTCCAGAGAAACGCCATTGAGCGTTTC
TGCGGGGAGGTGAGGCGCCTGTGCCATGCCGAGAGGAGGAAGGACTTCGTGTCAGAAGCCTACC
TGATCACACTGGGCAAGTTCATCAACATGTTCGCTGTGCTGGACGAGCTGAAGAACATGAAGTG
CAGTGTGAAGAACGACCACTCAGCGTACAAGAGGGCCGCTCAGTTTTTACGTAAAATGGCAGAT
CCACAGTCCATCCAGGAATCGCAGAATCTGTCCATGTTCCTGGCCAATCATAACAAGATCACAC
AGTCTCTGCAGCAGCAGCTCGAAGTGATTTCTGGCTACGAAGAGCTCCTGGCAGATATTGTGAA
TCTGTGTGTGGATTACTACGAGAACAGGATGTATTTGACGCCCAGTGAGAAACACATGCTTCTC
AAAGTCATGGGATTTGGTCTGTACCTGATGGATGGGAGTGTCAGTAACATCTATAAGTTGGATG
CCAAGAAAAGAATAAACTTATCCAAAATTGACAAGTACTTCAAGCAACTCCAGGTGGTTCCGCT
GTTTGGGGACATGCAAATAGAACTGGCAAGATACATCAAGACCAGCGCCCACTACGAGGAAAAT
AAATCTCGATGGACGTGCACATCCTCCGGCAGCAGCCCTCAGTACAACATCTGCGAGCAGATGA
TCCAGATCCGCGAGGACCACATGCGCTTCATTTCGGAGCTGGCACGCTACAGCAACAGCGAGGT
GGTCACGGGCTCGGGCCGCCAGGAGGCCCAGAAGACGGATGCGGAGTACCGCAAGCTCTTCGAC
CTGGCGCTGCAGGGCCTGCAGCTGCTGTCGCAGTGGAGCGCGCACGTGATGGAAGTGTATTCCT
GGAAGCTTGTGCACCCCACCGACAAGTACTCCAACAAGGACTGCCCCGACAGTGCTGAAGAGTA
CGAGCGTGCCACGCGCTACAACTACACCAGCGAGGAGAAGTTTGCCCTAGTGGAGGTGATCGCC
ATGATCAAAGGCCTGCAGGTGCTGATGGGCAGGATGGAGAGTGTGTTCAACCATGCCATCCGGC
ACACCGTCTATGCCGCACTGCAGGACTTCTCCCAGGTGACCCTTAGGGAGCCGCTGCGGCAGGC
CATCAAGAAGAAGAAGAACGTCATCCAGAGTGTCCTGCAGGCCATCAGGAAGACCGTGTGTGAC
TGGGAGACGGGGCATGAGCCCTTCAATGACCCAGCCTTGAGGGGCGAGAAGGACCCCAAGAGCG
GCTTCGACATAAAAGTACCACGCCGCGCCGTGGGACCCTCCAGCACTCAGCTTTACATGGTGAG
AACCATGCTAGAGTCCCTCATTGCAGACAAAAGTGGTTCCAAGAAAACCTTGAGAAGTAGCCTT
GAGGGGCCCACCATATTGGACATAGAAAAATTTCATCGAGAGTCATTCTTCTACACTCACTTGA
TAAATTTCAGTGAAACGCTGCAGCAGTGCTGTGACCTTTCGCAGCTGTGGTTCCGAGAGTTCTT
CCTGGAGCTGACCATGGGCAGGAGGATCCAGTTCCCCATTGAGATGTCGATGCCCTGGATCCTG
ACGGACCACATCCTGGAGACCAAGGAGGCATCGATGATGGAGTACGTGCTCTACTCCCTGGACC
TGTACAATGACAGCGCCCACTACGCGCTCACCAGGTTCAACAAACAGTTCCTCTACGACGAAAT
TGAGGCCGAGGTGAATCTATGTTTTGACCAATTTGTTTACAAGCTAGCAGACCAGATATTTGCC
TATTATAAGGTTATGGCAGGAAGTTTGCTTCTTGATAAACGGTTACGATCAGAATGCAAGAATC
AGGGAGCCACGATCCACCTCCCGCCGTCTAACCGCTACGAGACGCTGCTGAAGCAGAGGCACGT
GCAGCTCCTCGGCAGGTCAATAGACCTCAATCGTCTGATCACCCAGCGCGTCTCAGCAGCCATG
TCTAAGTCCCTGGAACTGGCGATTGGACGATTTGAAAGTGAAGATTTGACCTCCATAGTTGAGC
TGGATGGCCTGTTGGAAATCAACCGCATGACCCACAAGCTGCTGAGCCGGTACCTGACGCTGGA
CAGCTTCGATGCCATGTTCCGGGAGGCCAACCACAACGTGTCAGCGCCCTACGGGAGGATCACC
CTGCACGTCTTCTGGGAGCTCAACTATGACTTCCTGCCCAACTACTGCTACAACGGCTCTACCA
ACCGGTTTGTTCGGACAGTGTTACCATTTTCTCAGGAATTTCAAAGAGATAAGCAGCCTAATGC
ACAGCCTCAGTATCTGCATGGATCCAAGGCTTTGAACTTGGCCTACTCCAGCATTTACGGCAGC
TACCGGAACTTCGTGGGACCTCCACACTTTCAAGTCATCTGCCGGCTTCTCGGCTACCAGGGTA
TCGCCGTGGTCATGGAGGAGCTGCTGAAGGTCGTCAAGAGCCTGCTGCAAGGCACAATCCTGCA
GTACGTGAAGACACTGATGGAGGTGATGCCCAAGATCTGCCGCCTGCCCCGGCACGAGTACGGC
TCTCCTGGTATCCTGGAGTTCTTCCACCACCAGCTGAAGGACATCGTGGAGTATGCAGAGCTGA
AGACGGTGTGCTTCCAGAACCTGCGGGAGGTGGGGAACGCCATCCTCTTCTGCCTGCTCATCGA
GCAGAGCCTGTCTTTAGAAGAAGTGTGTGACCTGCTGCACGCGGCTCCTTTCCAGAACATCTTG
CCGCGAGTCCATGTGAAAGAGGGGGAGAGACTTGATGCCAAAATGAAAAGACTAGAATCAAAGT
ACGCCCCGCTGCATCTTGTCCCACTGATTGAAAGACTGGGGACCCCTCAGCAAATTGCCATCGC
AAGAGAGGGGGACCTGCTGACAAAGGAGCGCCTCTGCTGCGGCCTGTCCATGTTTGAGGTCATC
CTGACACGGATCCGGAGCTTTCTGGATGACCCCATCTGGCGCGGGCCTCTGCCCAGCAATGGGG
TCATGCATGTGGACGAGTGTGTGGAGTTTCACAGACTGTGGAGTGCCATGCAGTTTGTCTACTG
CATTCCCGTGGGGACACACGAGTTCACAGTCGAGCAGTGCTTTGGTGATGGGCTACACTGGGCT
GGCTGTATGATCATCGTACTTCTTGGGCAGCAGCGGCGTTTTGCTGTGCTGGATTTCTGCTACC
ATCTACTTAAAGTCCAGAAACATGATGGCAAAGATGAGATTATTAAAAATGTGCCTTTGAAGAA
GATGGTGGAGAGAATTCGCAAGTTCCAGATTCTCAATGATGAGATCATCACCATCCTGGATAAG
TACCTGAAGTCAGGCGACGGGGAGGGCACGCCAGTGGAGCATGTGCGCTGCTTCCAGCCGCCCA
TCCACCAGTCCCTCGCCAGCAGCTGAGGGCACGCGCTGCACTCCGTAACTCAACATGGCATGCC
TTTCTCTCCGTAAACTATTTAGTGAGATTTTTAGGGACTATTTTTCAGTATCTCTGTACCTGTT
AAAAGGGGTGCTTTTCAATCTAAAAACTTAATTTTATAAAATTGACTTATTTTTCTAGACTAAA
ATTGTATATGCTTTTGGTAATTAGGAACTCTTGAGAATATTGGCTGCTGATGGTTGCCATCACG
TTCCTAAAAATTGTTTTTCTATGGGATGTTCTGGCAGCTGTGTCATAAAATGCTGCTGGGTTCA
TTCATTCATTCCATAAGAAACTTAATACCAGCAAATGCATTAAATCCCTTGCCAGTTACCATTA
ACTGTAACTATTTAGCTTTTGTTTAGGGATCTTTCTGATGGTCTTTTATGAGCAATCTTAGTTC
TAAGTCATTGTTCCCATCCCTTTTTTGTGTGTTTCAGAAAATAGTGAACTTGATTCCCCTGCTT
CCACTAAATCCAGTTGTGACAAAATCTAACGTGACATCAGATCGAAAGGTTATAGAAATAAAAC
TAATGAGATCTA

hide sequence

RefSeq Acc Id:

XM_008976968 ⟹ XP_008975216

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	12,204,434 - 12,315,177 (-)	NCBI
NHGRI_mPanPan1	15	15,928,676 - 16,041,832 (-)	NCBI
PanPan1.1	15	20,462,755 - 20,573,684 (+)	NCBI

Sequence:

show sequence

GGAGCGCCGGGAGGAAGAGGCCGAGCCGGGAGAGCCCCCGCCCCGGGAGGAAGGGGAGGAGGCC
GAGTGTTTCCTGGCGCATTCCCGGCCAGCCCGAGTGACTCACTCGGCCAAGGAAACTCCCAGGG
CCCGCCCAGGACCCCCAAGCCGCCGCGGACGCAGAACAGGGGTCCTTATGTGTTGTTCCAGCCC
AGGATGGCGGCCCAGGTGACTCTGGAGGACGCGCTGTCCAACGTGGACCTCCTAGAGGAGCTGC
CCCTGCCCGACCAGCAGCCCTGCATCGAGCCCCCGCCATCCTCGCTGCTCTACCAGCCAAATTT
CAACACTAACTTTGAAGACAGAAATGCATTTGTTACTGGCATCGCAAGATACATCGAACAAGCC
ACCGTCCACTCTAGCATGAACGAGATGCTGGAGGAGGGCCAAGAATATGCTGTCATGCTGTACA
CCTGGAGGAGCTGCTCCCGGGCCATCCCACAGGTGAAATGTAACGAGCAGCCTAACAGAGTGGA
AATCTACGAGAAAACCGTGGAGGTTCTGGAGCCTGAGGTCACAAAACTGATGAATTTCATGTAC
TTCCAGAGAAACGCCATTGAGCGTTTCTGCGGGGAGGTGAGGCGCCTGTGCCATGCCGAGAGGA
GGAAGGACTTCGTGTCAGAAGCCTACCTGATCACACTGGGCAAGTTCATCAACATGTTCGCTGT
GCTGGACGAGCTGAAGAACATGAAGTGCAGTGTGAAGAACGACCACTCAGCGTACAAGAGGGCC
GCTCAGTTTTTACGTAAAATGGCAGATCCACAGTCCATCCAGGAATCGCAGAATCTGTCCATGT
TCCTGGCCAATCATAACAAGATCACACAGTCTCTGCAGCAGCAGCTCGAAGTGATTTCTGGCTA
CGAAGAGCTCCTGGCAGATATTGTGAATCTGTGTGTGGATTACTACGAGAACAGGATGTATTTG
ACGCCCAGTGAGAAACACATGCTTCTCAAAGTCATGGGATTTGGTCTGTACCTGATGGATGGGA
GTGTCAGTAACATCTATAAGTTGGATGCCAAGAAAAGAATAAACTTATCCAAAATTGACAAGTA
CTTCAAGCAACTCCAGGTGGTTCCGCTGTTTGGGGACATGCAAATAGAACTGGCAAGATACATC
AAGACCAGCGCCCACTACGAGGAAAATAAATCTCGATGGACGTGCACATCCTCCGGCAGCAGCC
CTCAGTACAACATCTGCGAGCAGATGATCCAGATCCGCGAGGACCACATGCGCTTCATTTCGGA
GCTGGCACGCTACAGCAACAGCGAGGTGGTCACGGGCTCGGGCCGCCAGGAGGCCCAGAAGACG
GATGCGGAGTACCGCAAGCTCTTCGACCTGGCGCTGCAGGGCCTGCAGCTGCTGTCGCAGTGGA
GCGCGCACGTGATGGAAGTGTATTCCTGGAAGCTTGTGCACCCCACCGACAAGTACTCCAACAA
GGACTGCCCCGACAGTGCTGAAGAGTACGAGCGTGCCACGCGCTACAACTACACCAGCGAGGAG
AAGTTTGCCCTAGTGGAGGTGATCGCCATGATCAAAGGCCTGCAGGTGCTGATGGGCAGGATGG
AGAGTGTGTTCAACCATGCCATCCGGCACACCGTCTATGCCGCACTGCAGGACTTCTCCCAGGT
GACCCTTAGGGAGCCGCTGCGGCAGGCCATCAAGAAGAAGAAGAACGTCATCCAGAGTGTCCTG
CAGGCCATCAGGAAGACCGTGTGTGACTGGGAGACGGGGCATGAGCCCTTCAATGACCCAGCCT
TGAGGGGCGAGAAGGACCCCAAGAGCGGCTTCGACATAAAAGTACCACGCCGCGCCGTGGGACC
CTCCAGCACTCAGCTTTACATGGTGAGAACCATGCTAGAGTCCCTCATTGCAGACAAAAGTGGT
TCCAAGAAAACCTTGAGAAGTAGCCTTGAGGGGCCCACCATATTGGACATAGAAAAATTTCATC
GAGAGTCATTCTTCTACACTCACTTGATAAATTTCAGTGAAACGCTGCAGCAGTGCTGTGACCT
TTCGCAGCTGTGGTTCCGAGAGTTCTTCCTGGAGCTGACCATGGGCAGGAGGATCCAGTTCCCC
ATTGAGATGTCGATGCCCTGGATCCTGACGGACCACATCCTGGAGACCAAGGAGGCATCGATGA
TGGAGTACGTGCTCTACTCCCTGGACCTGTACAATGACAGCGCCCACTACGCGCTCACCAGGTT
CAACAAACAGTTCCTCTACGACGAAATTGAGGCCGAGGTGAATCTATGTTTTGACCAATTTGTT
TACAAGCTAGCAGACCAGATATTTGCCTATTATAAGGTTATGGCAGGAAGTTTGCTTCTTGATA
AACGGTTACGATCAGAATGCAAGAATCAGGGAGCCACGATCCACCTCCCGCCGTCTAACCGCTA
CGAGACGCTGCTGAAGCAGAGGCACGTGCAGCTCCTCGGCAGGTCAATAGACCTCAATCGTCTG
ATCACCCAGCGCGTCTCAGCAGCCATGTCTAAGTCCCTGGAACTGGCGATTGGACGATTTGAAA
GTGAAGATTTGACCTCCATAGTTGAGCTGGATGGCCTGTTGGAAATCAACCGCATGACCCACAA
GCTGCTGAGCCGGTACCTGACGCTGGACAGCTTCGATGCCATGTTCCGGGAGGCCAACCACAAC
GTGTCAGCGCCCTACGGGAGGATCACCCTGCACGTCTTCTGGGAGCTCAACTATGACTTCCTGC
CCAACTACTGCTACAACGGCTCTACCAACCGGTTTGTTCGGACAGTGTTACCATTTTCTCAGGA
ATTTCAAAGAGATAAGCAGCCTAATGCACAGCCTCAGTATCTGCATGGATCCAAGGCTTTGAAC
TTGGCCTACTCCAGCATTTACGGCAGCTACCGGAACTTCGTGGGACCTCCACACTTTCAAGTCA
TCTGCCGGCTTCTCGGCTACCAGGGTATCGCCGTGGTCATGGAGGAGCTGCTGAAGGTCGTCAA
GAGCCTGCTGCAAGGCACAATCCTGCAGTACGTGAAGACACTGATGGAGGTGATGCCCAAGATC
TGCCGCCTGCCCCGGCACGAGTACGGCTCTCCTGGTATCCTGGAGTTCTTCCACCACCAGCTGA
AGGACATCGTGGAGTATGCAGAGCTGAAGACGGTGTGCTTCCAGAACCTGCGGGAGGTGGGGAA
CGCCATCCTCTTCTGCCTGCTCATCGAGCAGAGCCTGTCTTTAGAAGAAGTGTGTGACCTGCTG
CACGCGGCTCCTTTCCAGAACATCTTGCCGCGAGTCCATGTGAAAGAGGGGGAGAGACTTGATG
CCAAAATGAAAAGACTAGAATCAAAGTACGCCCCGCTGCATCTTGTCCCACTGATTGAAAGACT
GGGGACCCCTCAGCAAATTGCCATCGCAAGAGAGGGGGACCTGCTGACAAAGGAGCGCCTCTGC
TGCGGCCTGTCCATGTTTGAGGTCATCCTGACACGGATCCGGAGCTTTCTGGATGACCCCATCT
GGCGCGGGCCTCTGCCCAGCAATGGGGTCATGCATGTGGACGAGTGTGTGGAGTTTCACAGACT
GTGGAGTGCCATGCAGTTTGTCTACTGCATTCCCGTGGGGACACACGAGTTCACAGTCGAGCAG
TGCTTTGGTGATGGGCTACACTGGGCTGGCTGTATGATCATCGTACTTCTTGGGCAGCAGCGGC
GTTTTGCTGTGCTGGATTTCTGCTACCATCTACTTAAAGTCCAGAAACATGATGGCAAAGATGA
GATTATTAAAAATGTGCCTTTGAAGAAGATGGTGGAGAGAATTCGCAAGTTCCAGATTCTCAAT
GATGAGATCATCACCATCCTGGATAAGTACCTGAAGTCAGGCGACGGGGAGGGCACGCCAGTGG
AGCATGTGCGCTGCTTCCAGCCGCCCATCCACCAGTCCCTCGCCAGCAGCTGAGGGCACGCGCT
GCACTCCGTAACTCAACATGGCATGCCTTTCTCTCCGTAAACTATTTAGTGAGATTTTTAGGGA
CTATTTTTCAGTATCTCTGTACCTGTTAAAAGGGGTGCTTTTCAATCTAAAAACTTAATTTTAT
AAAATTGACTTATTTTTCTAGACTAAAATTGTATATGCTTTTGGTAATTAGGAACTCTTGAGAA
TATTGGCTGCTGATGGTTGCCATCACGTTCCTAAAAATTGTTTTTCTATGGGATGTTCTGGCAG
CTGTGTCATAAAATGCTGCTGGGTTCATTCATTCATTCCATAAGAAACTTAATACCAGCAAATG
CATTAAATCCCTTGCCAGTTACCATTAACTGTAACTATTTAGCTTTTGTTTAGGGATCTTTCTG
ATGGTCTTTTATGAGCAATCTTAGTTCTAAGTCATTGTTCCCATCCCTTTTTTGTGTGTTTCAG
AAAATAGTGAACTTGATTCCCCTGCTTCCACTAAATCCAGTTGTGACAAAATCTAACGTGACAT
CAGATCGAAAGGTTATAGAAATAAAACTAATGAGATCTA

hide sequence

RefSeq Acc Id:

XM_034951848 ⟹ XP_034807739

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	12,204,434 - 12,315,794 (-)	NCBI
NHGRI_mPanPan1	15	15,928,676 - 16,042,452 (-)	NCBI

RefSeq Acc Id:

XM_034951850 ⟹ XP_034807741

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	12,204,434 - 12,315,477 (-)	NCBI
NHGRI_mPanPan1	15	15,931,082 - 16,042,135 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003805989	(Get FASTA)	NCBI Sequence Viewer
	XP_008975216	(Get FASTA)	NCBI Sequence Viewer
	XP_034807739	(Get FASTA)	NCBI Sequence Viewer
	XP_034807741	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000008546.1
	ENSPPAP00000008552.1
	ENSPPAP00000008553.1
	ENSPPAP00000008554.1

RefSeq Acc Id:	XP_003805989 ⟸ XM_003805941
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZVG6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQAT VHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYF QRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAA QFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLT PSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIK TSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTD AEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDSAEEYERATRYNYTSEEK FALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQ AIRKTVCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGS KKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPI EMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVY KLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLI TQRVSAAMSKSLELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDSFDAMFREANHNV SAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNL AYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKIC RLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVCDLLH AAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCC GLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQC FGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILND EIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS hide sequence

RefSeq Acc Id:	XP_008975216 ⟸ XM_008976968
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZVG6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQAT VHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYF QRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAA QFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLT PSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIK TSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTD AEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDSAEEYERATRYNYTSEEK FALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQ AIRKTVCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGS KKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPI EMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVY KLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLI TQRVSAAMSKSLELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDSFDAMFREANHNV SAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNL AYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKIC RLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVCDLLH AAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCC GLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQC FGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILND EIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS hide sequence

Ensembl Acc Id:

ENSPPAP00000008554 ⟸ ENSPPAT00000031190

Ensembl Acc Id:

ENSPPAP00000008546 ⟸ ENSPPAT00000031182

Ensembl Acc Id:

ENSPPAP00000008553 ⟸ ENSPPAT00000031189

Ensembl Acc Id:

ENSPPAP00000008552 ⟸ ENSPPAT00000031188

RefSeq Acc Id:	XP_034807739 ⟸ XM_034951848
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZVG6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034807741 ⟸ XM_034951850
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZVG6 (UniProtKB/TrEMBL)

Protein Domains

CYRIA/CYRIB Rac1 binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000027494	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000031182.1	UniProtKB/TrEMBL
	ENSPPAT00000031188.1	UniProtKB/TrEMBL
	ENSPPAT00000031189.1	UniProtKB/TrEMBL
	ENSPPAT00000031190.1	UniProtKB/TrEMBL
InterPro	CYRIA/CYRIB_Rac1-bd	UniProtKB/TrEMBL
	Cytoplasmic_FMR1-int	UniProtKB/TrEMBL
KEGG Report	pps:100968966	UniProtKB/TrEMBL
NCBI Gene	CYFIP1	ENTREZGENE
PANTHER	CYTOPLASMIC FMR1-INTERACTING PROTEIN 1	UniProtKB/TrEMBL
	PTHR12195	UniProtKB/TrEMBL
Pfam	DUF1394	UniProtKB/TrEMBL
	FragX_IP	UniProtKB/TrEMBL
PIRSF	FMR1_interacting	UniProtKB/TrEMBL
PRINTS	CYTOFMRPINTP	UniProtKB/TrEMBL
UniProt	A0A2R8ZUA9_PANPA	UniProtKB/TrEMBL
	A0A2R8ZVG6	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZXN5_PANPA	UniProtKB/TrEMBL
	A0A2R8ZZZ2_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

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