FAT4 (FAT atypical cadherin 4) - Rat Genome Database

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Gene: FAT4 (FAT atypical cadherin 4) Pan paniscus
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Symbol: FAT4
Name: FAT atypical cadherin 4
RGD ID: 11864208
Description: ENCODES a protein that exhibits beta-catenin binding (inferred); cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); condensed mesenchymal cell proliferation (ortholog); digestive tract development (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Ascites (ortholog); CAKUT (ortholog); FOUND IN adherens junction (inferred); apical part of cell (inferred); catenin complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAT tumor suppressor homolog 4; protocadherin Fat 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23123,095,738 - 123,273,598 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14123,362,918 - 123,540,913 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04117,494,842 - 117,674,382 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14128,637,516 - 128,814,413 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4128,637,516 - 128,814,407 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FAT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23123,095,738 - 123,273,598 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14123,362,918 - 123,540,913 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04117,494,842 - 117,674,382 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14128,637,516 - 128,814,413 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4128,637,516 - 128,814,407 (+)Ensemblpanpan1.1panPan2
FAT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384125,314,955 - 125,492,932 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4125,314,918 - 125,492,932 (+)EnsemblGRCh38hg38GRCh38
GRCh374126,236,110 - 126,414,087 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364126,457,017 - 126,632,373 (+)NCBINCBI36Build 36hg18NCBI36
Build 344126,672,695 - 126,770,528NCBI
Celera4123,617,849 - 123,794,372 (+)NCBICelera
Cytogenetic Map4q28.1NCBI
HuRef4121,965,923 - 122,142,399 (+)NCBIHuRef
CHM1_14126,214,142 - 126,390,638 (+)NCBICHM1_1
T2T-CHM13v2.04128,617,253 - 128,795,252 (+)NCBIT2T-CHM13v2.0
Fat4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39338,939,867 - 39,066,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl338,941,089 - 39,066,134 (+)EnsemblGRCm39 Ensembl
GRCm38338,884,667 - 39,011,992 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl338,886,940 - 39,011,985 (+)EnsemblGRCm38mm10GRCm38
MGSCv37338,785,862 - 38,910,907 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36339,078,489 - 39,203,530 (+)NCBIMGSCv36mm8
Celera338,729,877 - 38,854,312 (+)NCBICelera
Cytogenetic Map3BNCBI
cM Map318.72NCBI
Fat4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82123,855,289 - 123,984,716 (+)NCBIGRCr8
mRatBN7.22121,927,266 - 122,056,700 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2121,927,942 - 122,056,707 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2128,499,081 - 128,627,276 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02126,611,655 - 126,739,826 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02121,240,615 - 121,368,809 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02125,751,818 - 125,879,398 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2125,752,130 - 125,879,387 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2126,267,658 - 126,284,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02145,349,239 - 145,477,455 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02145,864,192 - 145,880,594 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42125,847,465 - 125,975,620 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2116,853,380 - 116,981,485 (+)NCBICelera
Cytogenetic Map2q25NCBI
Fat4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542815,622,498 - 15,810,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542815,621,333 - 15,812,167 (-)NCBIChiLan1.0ChiLan1.0
FAT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11915,157,595 - 15,332,821 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1915,158,922 - 15,332,045 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1915,363,356 - 15,537,231 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01915,259,451 - 15,431,654 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1915,259,604 - 15,430,959 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11915,223,649 - 15,398,514 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01915,500,460 - 15,675,303 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01915,965,180 - 16,139,594 (-)NCBIUU_Cfam_GSD_1.0
Fat4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530163,414,526 - 63,583,319 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366623,537,925 - 3,690,877 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366623,537,917 - 3,704,012 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl899,148,496 - 99,310,519 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1899,141,967 - 99,312,131 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28105,998,766 - 106,018,349 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1772,498,182 - 72,686,607 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl772,500,264 - 72,685,546 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603751,514,689 - 51,708,405 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fat4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247776,095,643 - 6,292,980 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247776,095,166 - 6,293,142 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000041922   ⟹   ENSPPAP00000019171
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4128,637,516 - 128,814,407 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000041932   ⟹   ENSPPAP00000019180
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4128,638,138 - 128,813,253 (+)Ensembl
RefSeq Acc Id: XM_008969462   ⟹   XP_008967710
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23123,095,738 - 123,273,598 (+)NCBI
NHGRI_mPanPan14123,362,918 - 123,540,913 (+)NCBI
Mhudiblu_PPA_v04117,494,842 - 117,674,382 (+)NCBI
PanPan1.14128,637,516 - 128,814,413 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008969463   ⟹   XP_008967711
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23123,095,738 - 123,273,598 (+)NCBI
NHGRI_mPanPan14123,362,918 - 123,540,913 (+)NCBI
Mhudiblu_PPA_v04117,494,842 - 117,674,382 (+)NCBI
PanPan1.14128,637,516 - 128,814,413 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008967710 (Get FASTA)   NCBI Sequence Viewer  
  XP_008967711 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000019171.1
  ENSPPAP00000019180.1
RefSeq Acc Id: XP_008967710   ⟸   XM_008969462
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AP84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008967711   ⟸   XM_008969463
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AP84 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000019180   ⟸   ENSPPAT00000041932
Ensembl Acc Id: ENSPPAP00000019171   ⟸   ENSPPAT00000041922
Protein Domains
Cadherin   EGF-like   Laminin G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032760 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041922.1 UniProtKB/TrEMBL
  ENSPPAT00000041932.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro Cadherin-domain_protein UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
KEGG Report pps:100981077 UniProtKB/TrEMBL
NCBI Gene FAT4 ENTREZGENE
PANTHER DESMOGLEIN FAMILY MEMBER UniProtKB/TrEMBL
  FAT ATYPICAL CADHERIN 4 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  SM00112 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF49313 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A2R9AP84 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ATS1_PANPA UniProtKB/TrEMBL