WIPI2 (WD repeat domain, phosphoinositide interacting 2) - Rat Genome Database

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Gene: WIPI2 (WD repeat domain, phosphoinositide interacting 2) Pan paniscus
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Symbol: WIPI2
Name: WD repeat domain, phosphoinositide interacting 2
RGD ID: 11849566
Description: ENCODES a protein that exhibits phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); protein lipidation involved in autophagosome assembly (ortholog); protein localization to phagophore assembly site (ortholog); ASSOCIATED WITH Baraitser-Winter syndrome 1 (ortholog); INTELLECTUAL DEVELOPMENTAL DISORDER WITH SHORT STATURE AND VARIABLE SKELETAL ANOMALIES (ortholog); megacolon (ortholog); FOUND IN autophagosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WD repeat domain phosphoinositide-interacting protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,155,837 - 10,197,419 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1758,480,548 - 58,522,122 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v075,446,621 - 5,488,170 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.175,467,334 - 5,510,538 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl75,467,334 - 5,510,538 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WIPI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,155,837 - 10,197,419 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1758,480,548 - 58,522,122 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v075,446,621 - 5,488,170 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.175,467,334 - 5,510,538 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl75,467,334 - 5,510,538 (+)Ensemblpanpan1.1panPan2
WIPI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,190,233 - 5,233,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl75,190,196 - 5,233,840 (+)EnsemblGRCh38hg38GRCh38
GRCh3775,229,864 - 5,273,486 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,196,361 - 5,240,012 (+)NCBINCBI36Build 36hg18NCBI36
Celera75,188,959 - 5,232,605 (+)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef75,144,841 - 5,188,513 (+)NCBIHuRef
CHM1_175,229,458 - 5,273,114 (+)NCBICHM1_1
T2T-CHM13v2.075,307,988 - 5,351,615 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v275,276,190 - 5,319,841 (+)NCBI
Wipi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,615,269 - 142,655,427 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5142,613,453 - 142,656,343 (+)EnsemblGRCm39 Ensembl
GRCm385142,629,533 - 142,669,672 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,627,698 - 142,670,588 (+)EnsemblGRCm38mm10GRCm38
MGSCv375143,105,538 - 143,145,326 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365142,882,057 - 142,921,846 (+)NCBIMGSCv36mm8
Celera5139,684,840 - 139,724,789 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.53NCBI
Wipi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81217,024,876 - 17,053,306 (-)NCBIGRCr8
mRatBN7.21211,911,369 - 11,939,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,911,337 - 11,939,794 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,714,291 - 12,742,732 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,337,552 - 13,365,985 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,368,675 - 12,397,110 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,969,704 - 13,998,134 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,969,586 - 13,998,172 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,997,274 - 16,025,704 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,306,563 - 12,334,993 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11212,336,492 - 12,364,921 (-)NCBI
Celera1213,695,386 - 13,723,757 (-)NCBICelera
Cytogenetic Map12p11NCBI
Wipi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,090,349 - 10,130,384 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546010,090,343 - 10,132,724 (+)NCBIChiLan1.0ChiLan1.0
WIPI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1612,656,469 - 12,698,623 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl612,658,239 - 12,698,734 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha614,127,107 - 14,169,430 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0612,792,644 - 12,834,821 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl612,792,652 - 12,834,919 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1612,603,540 - 12,645,764 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0612,536,719 - 12,578,660 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0612,813,373 - 12,855,416 (-)NCBIUU_Cfam_GSD_1.0
Wipi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344140,918,058 - 140,955,730 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936765907,877 - 946,822 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936765909,118 - 946,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WIPI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl33,800,186 - 3,834,413 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.133,800,170 - 3,830,973 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,487,181 - 4,517,990 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WIPI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12816,504,557 - 16,558,670 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2816,502,435 - 16,558,650 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660905,423,866 - 5,470,061 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wipi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474028,306,052 - 28,346,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474028,306,655 - 28,346,430 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000046580   ⟹   ENSPPAP00000023755
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl75,467,334 - 5,510,538 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000046584   ⟹   ENSPPAP00000023759
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl75,467,342 - 5,510,538 (+)Ensembl
RefSeq Acc Id: XM_003819757   ⟹   XP_003819805
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2610,155,850 - 10,197,419 (+)NCBI
NHGRI_mPanPan1758,480,548 - 58,522,122 (+)NCBI
Mhudiblu_PPA_v075,446,640 - 5,488,170 (+)NCBI
PanPan1.175,467,334 - 5,510,538 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003819758   ⟹   XP_003819806
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2610,155,860 - 10,197,419 (+)NCBI
NHGRI_mPanPan1758,480,576 - 58,522,122 (+)NCBI
Mhudiblu_PPA_v075,446,640 - 5,488,170 (+)NCBI
PanPan1.175,467,334 - 5,510,538 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003819759   ⟹   XP_003819807
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2610,155,837 - 10,197,419 (+)NCBI
NHGRI_mPanPan1758,480,577 - 58,522,122 (+)NCBI
Mhudiblu_PPA_v075,446,621 - 5,488,170 (+)NCBI
PanPan1.175,467,342 - 5,510,538 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003819760   ⟹   XP_003819808
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2610,155,868 - 10,197,419 (+)NCBI
NHGRI_mPanPan1758,480,577 - 58,522,122 (+)NCBI
Mhudiblu_PPA_v075,446,638 - 5,488,170 (+)NCBI
PanPan1.175,467,342 - 5,510,538 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973173   ⟹   XP_008971421
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2610,155,871 - 10,197,419 (+)NCBI
NHGRI_mPanPan1758,480,581 - 58,522,122 (+)NCBI
Mhudiblu_PPA_v075,446,642 - 5,488,170 (+)NCBI
PanPan1.175,467,391 - 5,510,538 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003819805   ⟸   XM_003819757
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B6A6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003819806   ⟸   XM_003819758
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_003819807   ⟸   XM_003819759
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B946 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003819808   ⟸   XM_003819760
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008971421   ⟸   XM_008973173
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSPPAP00000023755   ⟸   ENSPPAT00000046580
Ensembl Acc Id: ENSPPAP00000023759   ⟸   ENSPPAT00000046584


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035034 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046580.1 UniProtKB/TrEMBL
  ENSPPAT00000046584.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro PROPPIN UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100985903 UniProtKB/TrEMBL
NCBI Gene WIPI2 ENTREZGENE
PANTHER WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED UniProtKB/TrEMBL
Pfam PROPPIN UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9B6A6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B946 ENTREZGENE, UniProtKB/TrEMBL