ZRANB3 (zinc finger RANBP2-type containing 3) - Rat Genome Database

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Gene: ZRANB3 (zinc finger RANBP2-type containing 3) Pan paniscus
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Symbol: ZRANB3
Name: zinc finger RANBP2-type containing 3
RGD ID: 11835617
Description: ENCODES a protein that exhibits DNA helicase activity (ortholog); INVOLVED IN DNA damage response (inferred); DNA repair (inferred); negative regulation of DNA recombination (inferred); ASSOCIATED WITH WHIM Syndrome (ortholog); FOUND IN nuclear replication fork (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA annealing helicase and endonuclease ZRANB3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21339,400,603 - 39,755,767 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B39,415,302 - 39,770,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B24,331,731 - 24,665,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B139,271,306 - 139,603,946 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B139,234,909 - 139,577,193 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZRANB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21339,400,603 - 39,755,767 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B39,415,302 - 39,770,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B24,331,731 - 24,665,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B139,271,306 - 139,603,946 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B139,234,909 - 139,577,193 (-)Ensemblpanpan1.1panPan2
ZRANB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,196,969 - 135,531,218 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2135,136,916 - 135,531,218 (-)EnsemblGRCh38hg38GRCh38
GRCh372135,954,539 - 136,288,788 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362135,674,041 - 136,005,276 (-)NCBINCBI36Build 36hg18NCBI36
Build 342135,728,218 - 135,830,163NCBI
Celera2129,670,506 - 129,999,572 (-)NCBICelera
Cytogenetic Map2q21.3NCBI
HuRef2127,950,131 - 128,281,480 (-)NCBIHuRef
CHM1_12135,962,511 - 136,293,706 (-)NCBICHM1_1
T2T-CHM13v2.02135,637,447 - 135,971,741 (-)NCBIT2T-CHM13v2.0
Zranb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391127,881,916 - 128,030,799 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1127,881,921 - 128,030,784 (-)EnsemblGRCm39 Ensembl
GRCm381127,954,179 - 128,103,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1127,954,184 - 128,103,047 (-)EnsemblGRCm38mm10GRCm38
MGSCv371129,850,763 - 129,998,985 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,781,725 - 129,930,593 (-)NCBIMGSCv36mm8
Celera1130,582,923 - 130,729,435 (-)NCBICelera
Cytogenetic Map1E3NCBI
cM Map155.8NCBI
Zranb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81341,993,110 - 42,148,298 (-)NCBIGRCr8
mRatBN7.21339,440,653 - 39,595,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1339,440,889 - 39,595,670 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01344,661,375 - 44,812,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,661,398 - 44,798,543 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01349,745,984 - 49,897,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41340,648,221 - 40,803,738 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1339,815,144 - 39,969,876 (-)NCBICelera
Cytogenetic Map13q13NCBI
Zranb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554402,680,787 - 2,888,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554402,683,041 - 2,907,859 (-)NCBIChiLan1.0ChiLan1.0
ZRANB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11938,003,273 - 38,302,598 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1937,957,421 - 38,301,888 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,247,332 - 38,546,267 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01939,448,903 - 39,748,462 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1939,447,977 - 39,747,839 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11938,091,050 - 38,390,605 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01938,251,868 - 38,553,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01939,487,157 - 39,786,272 (-)NCBIUU_Cfam_GSD_1.0
Zranb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303101,057,646 - 101,288,879 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646940,328,787 - 40,609,533 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646940,328,850 - 40,558,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZRANB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,414,757 - 16,727,841 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,414,291 - 16,727,659 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21519,093,163 - 19,182,218 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZRANB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11019,428,139 - 19,739,886 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1019,427,652 - 19,572,384 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660612,724,205 - 3,069,554 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zranb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473234,556,784 - 34,848,965 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473234,561,249 - 34,848,093 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000035302   ⟹   ENSPPAP00000012636
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B139,234,909 - 139,301,967 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000035333   ⟹   ENSPPAP00000012667
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B139,271,985 - 139,577,193 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000035334   ⟹   ENSPPAP00000012668
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B139,271,985 - 139,426,101 (-)Ensembl
RefSeq Acc Id: XM_034954087   ⟹   XP_034809978
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,401,371 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,416,273 - 39,770,737 (+)NCBI
Mhudiblu_PPA_v02B24,332,315 - 24,663,039 (+)NCBI
RefSeq Acc Id: XM_034954088   ⟹   XP_034809979
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,401,194 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,416,164 - 39,770,737 (+)NCBI
Mhudiblu_PPA_v02B24,332,204 - 24,663,039 (+)NCBI
RefSeq Acc Id: XM_034954090   ⟹   XP_034809981
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,400,677 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,415,703 - 39,770,737 (+)NCBI
Mhudiblu_PPA_v02B24,331,760 - 24,663,039 (+)NCBI
RefSeq Acc Id: XM_034954093   ⟹   XP_034809984
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,427,509 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,442,479 - 39,770,737 (+)NCBI
Mhudiblu_PPA_v02B24,358,529 - 24,663,039 (+)NCBI
RefSeq Acc Id: XM_055108541   ⟹   XP_054964516
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,400,603 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,415,302 - 39,770,737 (+)NCBI
RefSeq Acc Id: XM_055108543   ⟹   XP_054964518
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,578,182 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,593,152 - 39,770,737 (+)NCBI
RefSeq Acc Id: XM_057301406   ⟹   XP_057157389
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,401,369 - 39,734,643 (+)NCBI
NHGRI_mPanPan12B39,416,273 - 39,770,737 (+)NCBI
RefSeq Acc Id: XM_063595169   ⟹   XP_063451239
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,400,677 - 39,734,643 (+)NCBI
RefSeq Acc Id: XM_063595170   ⟹   XP_063451240
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,400,677 - 39,755,767 (+)NCBI
RefSeq Acc Id: XM_063595171   ⟹   XP_063451241
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,401,371 - 39,734,643 (+)NCBI
RefSeq Acc Id: XM_063595172   ⟹   XP_063451242
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21339,400,619 - 39,734,643 (+)NCBI
RefSeq Acc Id: XP_034809981   ⟸   XM_034954090
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809979   ⟸   XM_034954088
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809978   ⟸   XM_034954087
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809984   ⟸   XM_034954093
- Peptide Label: isoform X6
- UniProtKB: A0A2R9A5U3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000012667   ⟸   ENSPPAT00000035333
Ensembl Acc Id: ENSPPAP00000012668   ⟸   ENSPPAT00000035334
Ensembl Acc Id: ENSPPAP00000012636   ⟸   ENSPPAT00000035302
RefSeq Acc Id: XP_054964516   ⟸   XM_055108541
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054964518   ⟸   XM_055108543
- Peptide Label: isoform X7
- UniProtKB: A0A2R9A5U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057157389   ⟸   XM_057301406
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451242   ⟸   XM_063595172
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451240   ⟸   XM_063595170
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451239   ⟸   XM_063595169
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451241   ⟸   XM_063595171
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AB52 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029480 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035302.1 UniProtKB/TrEMBL
  ENSPPAT00000035333.1 UniProtKB/TrEMBL
  ENSPPAT00000035334.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.50 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Zn-finger domain of Sec23/24 UniProtKB/TrEMBL
InterPro Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  HNH UniProtKB/TrEMBL
  HNH_nuc UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
NCBI Gene ZRANB3 ENTREZGENE
PANTHER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 UniProtKB/TrEMBL
  DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER UniProtKB/TrEMBL
Pfam Helicase_C UniProtKB/TrEMBL
  HNH UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  zf-RanBP UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  HNHc UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90209 UniProtKB/TrEMBL
UniProt A0A2R9A5U3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AAH3_PANPA UniProtKB/TrEMBL
  A0A2R9AB52 ENTREZGENE, UniProtKB/TrEMBL