DNM1L (dynamin 1 like) - Rat Genome Database

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Gene: DNM1L (dynamin 1 like) Pan paniscus
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Symbol: DNM1L
Name: dynamin 1 like
RGD ID: 11821346
Description: ENCODES a protein that exhibits BH2 domain binding (ortholog); clathrin binding (ortholog); identical protein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); cellular response to hypoxia (ortholog); cellular response to lipid (ortholog); PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); arrhythmogenic right ventricular dysplasia 9 (ortholog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN clathrin coat of trans-Golgi network vesicle (ortholog); endoplasmic reticulum (ortholog); Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynamin-1-like protein-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21064,005,917 - 64,070,389 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11264,000,313 - 64,066,785 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01253,476,553 - 53,541,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11256,077,504 - 56,142,376 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1256,077,504 - 56,142,376 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DNM1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21064,005,917 - 64,070,389 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11264,000,313 - 64,066,785 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01253,476,553 - 53,541,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11256,077,504 - 56,142,376 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1256,077,504 - 56,142,376 (-)Ensemblpanpan1.1panPan2
DNM1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381232,679,301 - 32,745,650 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1232,679,200 - 32,745,650 (+)EnsemblGRCh38hg38GRCh38
GRCh371232,832,235 - 32,898,584 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361232,723,491 - 32,788,621 (+)NCBINCBI36Build 36hg18NCBI36
Build 341232,723,490 - 32,787,810NCBI
Celera1212,653,086 - 12,719,281 (+)NCBICelera
Cytogenetic Map12p11.21NCBI
HuRef1232,584,423 - 32,651,060 (+)NCBIHuRef
CHM1_11232,798,646 - 32,865,086 (+)NCBICHM1_1
T2T-CHM13v2.01232,555,588 - 32,621,929 (+)NCBIT2T-CHM13v2.0
Dnm1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,130,092 - 16,176,863 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,130,094 - 16,176,823 (-)EnsemblGRCm39 Ensembl
GRCm381616,312,228 - 16,359,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1616,312,230 - 16,358,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv371616,312,326 - 16,359,123 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361616,225,811 - 16,272,608 (-)NCBIMGSCv36mm8
Celera1616,883,274 - 16,930,064 (-)NCBICelera
Cytogenetic Map16A2NCBI
cM Map1610.12NCBI
Dnm1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81198,084,049 - 98,135,663 (+)NCBIGRCr8
mRatBN7.21184,581,216 - 84,632,382 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1184,581,216 - 84,631,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1193,314,036 - 93,362,103 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,975,178 - 86,023,244 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,028,777 - 85,076,843 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01188,830,968 - 88,882,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,830,957 - 88,880,198 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,885,295 - 91,936,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,617,236 - 86,665,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,657,172 - 86,706,365 (-)NCBI
Celera1183,326,642 - 83,375,373 (+)NCBICelera
Cytogenetic Map11q23NCBI
Dnm1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555053,023,018 - 3,081,680 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555053,025,742 - 3,081,491 (-)NCBIChiLan1.0ChiLan1.0
DNM1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12716,161,855 - 16,211,983 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2716,163,357 - 16,211,957 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2730,213,206 - 30,264,757 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02716,342,630 - 16,394,291 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2716,341,228 - 16,394,252 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12716,151,140 - 16,202,287 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02716,183,766 - 16,235,121 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02730,361,257 - 30,412,627 (+)NCBIUU_Cfam_GSD_1.0
Dnm1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494576,743,024 - 76,799,054 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366073,576,392 - 3,632,554 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366073,576,357 - 3,632,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl541,570,282 - 41,636,028 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1541,571,054 - 41,636,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2544,756,967 - 44,785,760 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNM1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11132,114,642 - 32,178,330 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1132,114,675 - 32,177,661 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660692,716,938 - 2,783,519 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnm1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247783,391,690 - 3,475,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000057174   ⟹   ENSPPAP00000034293
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,077,504 - 56,142,376 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057211   ⟹   ENSPPAP00000034330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,077,504 - 56,142,371 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057216   ⟹   ENSPPAP00000034335
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,077,504 - 56,142,371 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057223   ⟹   ENSPPAP00000034342
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,077,504 - 56,142,348 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057226   ⟹   ENSPPAP00000034345
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,077,504 - 56,142,347 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057231   ⟹   ENSPPAP00000034350
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,077,504 - 56,120,570 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057255   ⟹   ENSPPAP00000034373
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,079,701 - 56,142,212 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057260   ⟹   ENSPPAP00000034378
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1256,111,961 - 56,142,212 (-)Ensembl
RefSeq Acc Id: XM_003813726   ⟹   XP_003813774
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,332 (-)NCBI
NHGRI_mPanPan11264,002,313 - 64,066,728 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,410 (-)NCBI
PanPan1.11256,077,504 - 56,142,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008966287   ⟹   XP_008964535
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,389 (-)NCBI
NHGRI_mPanPan11264,000,313 - 64,066,785 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,421 (-)NCBI
PanPan1.11256,077,504 - 56,142,376 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008966288   ⟹   XP_008964536
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,306 (-)NCBI
NHGRI_mPanPan11264,002,313 - 64,066,702 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,382 (-)NCBI
PanPan1.11256,077,504 - 56,142,347 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008966289   ⟹   XP_008964537
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,296 (-)NCBI
NHGRI_mPanPan11264,002,313 - 64,066,692 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,382 (-)NCBI
PanPan1.11256,077,504 - 56,142,348 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008966291   ⟹   XP_008964539
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,349 (-)NCBI
NHGRI_mPanPan11264,002,313 - 64,066,745 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,410 (-)NCBI
PanPan1.11256,077,504 - 56,142,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008966292   ⟹   XP_008964540
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,296 (-)NCBI
NHGRI_mPanPan11264,000,313 - 64,066,692 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,383 (-)NCBI
PanPan1.11256,077,504 - 56,142,347 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008966293   ⟹   XP_008964541
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,362 (-)NCBI
NHGRI_mPanPan11264,002,313 - 64,066,758 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,410 (-)NCBI
PanPan1.11256,077,504 - 56,142,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034936050   ⟹   XP_034791941
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,070,296 (-)NCBI
NHGRI_mPanPan11264,000,313 - 64,066,692 (-)NCBI
Mhudiblu_PPA_v01253,476,553 - 53,541,383 (-)NCBI
RefSeq Acc Id: XM_057299472   ⟹   XP_057155455
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21064,005,917 - 64,048,002 (-)NCBI
NHGRI_mPanPan11264,002,313 - 64,044,398 (-)NCBI
RefSeq Acc Id: XP_008964535   ⟸   XM_008966287
- Peptide Label: isoform X7
- UniProtKB: A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964541   ⟸   XM_008966293
- Peptide Label: isoform X8
- UniProtKB: A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964539   ⟸   XM_008966291
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813774   ⟸   XM_003813726
- Peptide Label: isoform X3
- UniProtKB: A0A2R9C0Q2 (UniProtKB/TrEMBL),   A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964537   ⟸   XM_008966289
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BXC8 (UniProtKB/TrEMBL),   A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964540   ⟸   XM_008966292
- Peptide Label: isoform X6
- UniProtKB: A0A2R9C0R1 (UniProtKB/TrEMBL),   A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964536   ⟸   XM_008966288
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BXG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034791941   ⟸   XM_034936050
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BXG2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000034293   ⟸   ENSPPAT00000057174
Ensembl Acc Id: ENSPPAP00000034335   ⟸   ENSPPAT00000057216
Ensembl Acc Id: ENSPPAP00000034330   ⟸   ENSPPAT00000057211
Ensembl Acc Id: ENSPPAP00000034342   ⟸   ENSPPAT00000057223
Ensembl Acc Id: ENSPPAP00000034345   ⟸   ENSPPAT00000057226
Ensembl Acc Id: ENSPPAP00000034350   ⟸   ENSPPAT00000057231
Ensembl Acc Id: ENSPPAP00000034373   ⟸   ENSPPAT00000057255
Ensembl Acc Id: ENSPPAP00000034378   ⟸   ENSPPAT00000057260
RefSeq Acc Id: XP_057155455   ⟸   XM_057299472
- Peptide Label: isoform X9
- UniProtKB: A0A2R9C0R7 (UniProtKB/TrEMBL)
Protein Domains
Dynamin-type G   GED


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039981 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057174.1 UniProtKB/TrEMBL
  ENSPPAT00000057211.1 UniProtKB/TrEMBL
  ENSPPAT00000057216.1 UniProtKB/TrEMBL
  ENSPPAT00000057223.1 UniProtKB/TrEMBL
  ENSPPAT00000057226.1 UniProtKB/TrEMBL
  ENSPPAT00000057231.1 UniProtKB/TrEMBL
  ENSPPAT00000057255.1 UniProtKB/TrEMBL
  ENSPPAT00000057260.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  Dynamin, middle domain UniProtKB/TrEMBL
InterPro Dynamin_GTPase UniProtKB/TrEMBL
  Dynamin_GTPase_CS UniProtKB/TrEMBL
  Dynamin_N UniProtKB/TrEMBL
  Dynamin_SF UniProtKB/TrEMBL
  Dynamin_stalk UniProtKB/TrEMBL
  G_DYNAMIN_dom UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
  GED_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene DNM1L ENTREZGENE
PANTHER PTHR11566 UniProtKB/TrEMBL
  PTHR11566:SF39 UniProtKB/TrEMBL
Pfam Dynamin_M UniProtKB/TrEMBL
  Dynamin_N UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
PRINTS DYNAMIN UniProtKB/TrEMBL
PROSITE G_DYNAMIN_1 UniProtKB/TrEMBL
  G_DYNAMIN_2 UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
SMART DYNc UniProtKB/TrEMBL
  GED UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9BX85_PANPA UniProtKB/TrEMBL
  A0A2R9BXC8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BXG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BXG8_PANPA UniProtKB/TrEMBL
  A0A2R9C0P6_PANPA UniProtKB/TrEMBL
  A0A2R9C0Q2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C0R1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C0R7 ENTREZGENE, UniProtKB/TrEMBL