HMGA1 (high mobility group AT-hook 1) - Rat Genome Database

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Gene: HMGA1 (high mobility group AT-hook 1) Pan paniscus
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Symbol: HMGA1
Name: high mobility group AT-hook 1
RGD ID: 11768829
Description: ENCODES a protein that exhibits 5'-deoxyribose-5-phosphate lyase activity (ortholog); chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN autophagy (ortholog); B cell differentiation (ortholog); base-excision repair (ortholog); PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH hyperglycemia (ortholog); Insulin Resistance (ortholog); leiomyosarcoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); male germ cell nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: high mobility group protein HMG-I/HMG-Y
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2548,712,783 - 48,722,294 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1644,580,061 - 44,589,567 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0633,807,171 - 33,816,603 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1634,914,923 - 34,920,482 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HMGA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2548,712,783 - 48,722,294 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1644,580,061 - 44,589,567 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0633,807,171 - 33,816,603 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1634,914,923 - 34,920,482 (+)NCBIpanpan1.1PanPan1.1panPan2
HMGA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38634,236,873 - 34,246,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl634,236,873 - 34,246,231 (+)EnsemblGRCh38hg38GRCh38
GRCh37634,204,650 - 34,214,008 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36634,312,628 - 34,321,986 (+)NCBINCBI36Build 36hg18NCBI36
Build 34634,314,545 - 34,321,986NCBI
Celera635,758,945 - 35,768,381 (+)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef633,927,318 - 33,936,673 (+)NCBIHuRef
CHM1_1634,207,231 - 34,216,597 (+)NCBICHM1_1
T2T-CHM13v2.0634,060,576 - 34,069,936 (+)NCBIT2T-CHM13v2.0
Hmga1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391727,774,798 - 27,782,649 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1727,775,471 - 27,782,648 (+)EnsemblGRCm39 Ensembl
GRCm381727,556,574 - 27,563,672 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,556,497 - 27,563,674 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,762,794 - 120,764,419 (+)EnsemblGRCm38mm10GRCm38
MGSCv371727,693,519 - 27,700,617 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361727,284,171 - 27,291,260 (+)NCBIMGSCv36mm8
Celera1728,108,639 - 28,115,776 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.5NCBI
Hmga1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,612,902 - 5,620,596 (+)NCBIGRCr8
mRatBN7.2205,611,088 - 5,618,755 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl205,611,694 - 5,618,752 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx206,327,117 - 6,330,067 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,688,869 - 5,691,819 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0206,169,005 - 6,171,956 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0207,132,501 - 7,140,155 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,136,007 - 7,138,980 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,334,866 - 9,342,510 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,769,052 - 5,772,269 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1205,769,278 - 5,772,496 (+)NCBI
Celera207,177,471 - 7,180,533 (+)NCBICelera
Cytogenetic Map20p12NCBI
Hmga1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,478,414 - 2,486,809 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554372,478,414 - 2,486,809 (+)NCBIChiLan1.0ChiLan1.0
HMGA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1123,528,818 - 3,538,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl123,533,102 - 3,538,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha123,544,725 - 3,554,094 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0123,865,251 - 3,874,712 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl123,865,303 - 3,888,352 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1123,527,697 - 3,537,024 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0123,609,068 - 3,618,412 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0123,707,513 - 3,716,880 (+)NCBIUU_Cfam_GSD_1.0
Hmga1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494639,156,880 - 39,164,376 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647624,795,877 - 24,801,567 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647624,795,854 - 24,803,138 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMGA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl730,320,410 - 30,329,408 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1730,320,090 - 30,329,413 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,981,570 - 34,990,089 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q11NCBI
HMGA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11737,848,110 - 37,857,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1737,849,412 - 37,853,880 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604434,150,889 - 34,160,977 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hmga1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475422,892,226 - 22,898,807 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475422,888,052 - 22,900,685 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_034961880   ⟹   XP_034817771
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,712,783 - 48,722,294 (+)NCBI
NHGRI_mPanPan1644,580,061 - 44,589,567 (+)NCBI
Mhudiblu_PPA_v0633,807,172 - 33,816,603 (+)NCBI
RefSeq Acc Id: XM_034961881   ⟹   XP_034817772
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,712,888 - 48,722,294 (+)NCBI
NHGRI_mPanPan1644,580,167 - 44,589,567 (+)NCBI
Mhudiblu_PPA_v0633,807,209 - 33,816,603 (+)NCBI
RefSeq Acc Id: XM_034961882   ⟹   XP_034817773
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,712,857 - 48,722,294 (+)NCBI
NHGRI_mPanPan1644,580,135 - 44,589,567 (+)NCBI
Mhudiblu_PPA_v0633,807,171 - 33,816,603 (+)NCBI
RefSeq Acc Id: XM_034961883   ⟹   XP_034817774
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,712,883 - 48,722,294 (+)NCBI
NHGRI_mPanPan1644,580,162 - 44,589,567 (+)NCBI
Mhudiblu_PPA_v0633,807,204 - 33,816,603 (+)NCBI
RefSeq Acc Id: XM_055113484   ⟹   XP_054969459
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,713,638 - 48,722,294 (+)NCBI
NHGRI_mPanPan1644,580,963 - 44,589,567 (+)NCBI
RefSeq Acc Id: XM_055113485   ⟹   XP_054969460
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,713,652 - 48,722,294 (+)NCBI
NHGRI_mPanPan1644,580,939 - 44,589,567 (+)NCBI
RefSeq Acc Id: XM_063604846   ⟹   XP_063460916
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,713,929 - 48,722,294 (+)NCBI
RefSeq Acc Id: XM_063604847   ⟹   XP_063460917
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2548,714,842 - 48,722,294 (+)NCBI
RefSeq Acc Id: XP_034817773   ⟸   XM_034961882
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034817771   ⟸   XM_034961880
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AIQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817774   ⟸   XM_034961883
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034817772   ⟸   XM_034961881
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AIQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054969460   ⟸   XM_055113485
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054969459   ⟸   XM_055113484
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AIQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063460916   ⟸   XM_063604846
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AIQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063460917   ⟸   XM_063604847
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030660 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000037700.1 UniProtKB/TrEMBL
InterPro AT_hook_DNA-bd_motif UniProtKB/TrEMBL
  HMGA UniProtKB/TrEMBL
  HMGI/Y_DNA-bd_CS UniProtKB/TrEMBL
NCBI Gene HMGA1 ENTREZGENE
PANTHER HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y UniProtKB/TrEMBL
  HIGH MOBILITY GROUP PROTEINS HMG-A AND C UniProtKB/TrEMBL
PRINTS ATHOOK UniProtKB/TrEMBL
  HIGHMOBLTYIY UniProtKB/TrEMBL
PROSITE HMGI_Y UniProtKB/TrEMBL
SMART AT_hook UniProtKB/TrEMBL
UniProt A0A2R9AIQ2 ENTREZGENE, UniProtKB/TrEMBL