LMAN2 (lectin, mannose binding 2) - Rat Genome Database

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Gene: LMAN2 (lectin, mannose binding 2) Pan paniscus
Analyze
Symbol: LMAN2
Name: lectin, mannose binding 2
RGD ID: 11757275
Description: ENCODES a protein that exhibits carbohydrate binding (inferred); D-mannose binding (inferred); heat shock protein binding (inferred); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); positive regulation of phagocytosis (inferred); retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (inferred); ASSOCIATED WITH Chromosome 5, Trisomy 5q (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); Ehlers-Danlos syndrome spondylodysplastic type 2 (ortholog); FOUND IN COPI-coated vesicle (ortholog); cytoplasmic vesicle (ortholog); exocytic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vesicular integral-membrane protein VIP36
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24172,400,702 - 172,451,594 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15170,541,726 - 170,576,980 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05172,619,011 - 172,653,303 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15179,696,018 - 179,716,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5179,696,018 - 179,716,076 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LMAN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24172,400,702 - 172,451,594 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15170,541,726 - 170,576,980 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05172,619,011 - 172,653,303 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15179,696,018 - 179,716,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5179,696,018 - 179,716,076 (-)Ensemblpanpan1.1panPan2
LMAN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385177,331,567 - 177,351,668 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5177,315,805 - 177,351,840 (-)EnsemblGRCh38hg38GRCh38
GRCh375176,758,568 - 176,778,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365176,691,357 - 176,711,254 (-)NCBINCBI36Build 36hg18NCBI36
Build 345176,691,356 - 176,711,254NCBI
Celera5171,722,374 - 171,742,745 (+)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5171,679,241 - 171,699,552 (-)NCBIHuRef
CHM1_15176,191,595 - 176,211,934 (-)NCBICHM1_1
T2T-CHM13v2.05177,874,790 - 177,894,892 (-)NCBIT2T-CHM13v2.0
Lman2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,491,646 - 55,510,596 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1355,491,646 - 55,510,596 (-)EnsemblGRCm39 Ensembl
GRCm381355,343,833 - 55,362,783 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1355,343,833 - 55,362,783 (-)EnsemblGRCm38mm10GRCm38
MGSCv371355,445,194 - 55,464,144 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361355,353,455 - 55,372,405 (-)NCBIMGSCv36mm8
Celera1356,399,474 - 56,418,646 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1329.8NCBI
Lman2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8179,274,362 - 9,294,950 (+)NCBIGRCr8
mRatBN7.2179,269,236 - 9,286,923 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,269,022 - 9,287,265 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx179,285,747 - 9,303,376 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,815,450 - 10,833,082 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0179,282,139 - 9,299,768 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,798,136 - 9,815,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,797,907 - 9,816,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,907,481 - 11,925,373 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,313,291 - 15,331,470 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11715,313,257 - 15,331,470 (+)NCBI
Celera179,347,770 - 9,365,303 (+)NCBICelera
Cytogenetic Map17p14NCBI
Lman2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540829,581,737 - 29,597,240 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540829,581,737 - 29,597,240 (-)NCBIChiLan1.0ChiLan1.0
LMAN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,002,963 - 36,023,788 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl436,002,341 - 36,023,787 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha435,970,558 - 35,991,241 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0436,369,371 - 36,390,131 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl436,369,392 - 36,393,670 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1436,194,590 - 36,215,063 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0436,380,795 - 36,401,235 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0436,890,050 - 36,910,748 (+)NCBIUU_Cfam_GSD_1.0
Lman2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213122,594,473 - 122,613,534 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365971,616,297 - 1,638,569 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365971,619,380 - 1,638,469 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMAN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl280,595,334 - 80,609,594 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1280,595,064 - 80,636,168 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2282,232,345 - 82,273,555 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LMAN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12379,337,076 - 79,358,653 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2379,336,997 - 79,358,421 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607510,525,633 - 10,547,226 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lman2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473312,727,838 - 12,747,441 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473312,728,061 - 12,747,093 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000061651   ⟹   ENSPPAP00000038744
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5179,696,018 - 179,716,076 (-)Ensembl
RefSeq Acc Id: XM_003806854   ⟹   XP_003806902
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24172,415,800 - 172,437,425 (-)NCBI
NHGRI_mPanPan15170,555,344 - 170,576,974 (-)NCBI
Mhudiblu_PPA_v05172,633,236 - 172,653,303 (-)NCBI
PanPan1.15179,696,018 - 179,716,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024928817   ⟹   XP_024784585
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24172,415,800 - 172,437,432 (-)NCBI
NHGRI_mPanPan15170,555,344 - 170,576,980 (-)NCBI
Mhudiblu_PPA_v05172,633,236 - 172,653,212 (-)NCBI
PanPan1.15179,696,018 - 179,716,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034961063   ⟹   XP_034816954
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24172,400,702 - 172,437,431 (-)NCBI
NHGRI_mPanPan15170,541,726 - 170,576,979 (-)NCBI
Mhudiblu_PPA_v05172,619,011 - 172,653,210 (-)NCBI
RefSeq Acc Id: XM_063604312   ⟹   XP_063460382
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24172,415,800 - 172,451,594 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003806902 (Get FASTA)   NCBI Sequence Viewer  
  XP_024784585 (Get FASTA)   NCBI Sequence Viewer  
  XP_034816954 (Get FASTA)   NCBI Sequence Viewer  
  XP_063460382 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038744
  ENSPPAP00000038744.1
RefSeq Acc Id: XP_003806902   ⟸   XM_003806854
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CA64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024784585   ⟸   XM_024928817
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034816954   ⟸   XM_034961063
- Peptide Label: isoform X3
Ensembl Acc Id: ENSPPAP00000038744   ⟸   ENSPPAT00000061651
RefSeq Acc Id: XP_063460382   ⟸   XM_063604312
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CA64 (UniProtKB/TrEMBL)
Protein Domains
L-type lectin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042088 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061651.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Intracellular_Lectin-GPT UniProtKB/TrEMBL
  Lectin_leg UniProtKB/TrEMBL
  VIP36_lectin UniProtKB/TrEMBL
KEGG Report pps:100992233 UniProtKB/TrEMBL
NCBI Gene LMAN2 ENTREZGENE
PANTHER VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 UniProtKB/TrEMBL
  VESICULAR MANNOSE-BINDING LECTIN UniProtKB/TrEMBL
Pfam Lectin_leg-like UniProtKB/TrEMBL
PROSITE L_LECTIN_LIKE UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt A0A2R9CA64 ENTREZGENE, UniProtKB/TrEMBL