GALK1 (galactokinase 1) - Rat Genome Database

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Pathways
Gene: GALK1 (galactokinase 1) Pan paniscus
Analyze
Symbol: GALK1
Name: galactokinase 1
RGD ID: 11750196
Description: ENCODES a protein that exhibits ATP binding (ortholog); galactokinase activity (ortholog); galactose binding (ortholog); INVOLVED IN carbohydrate phosphorylation (ortholog); galactose metabolic process (ortholog); PARTICIPATES IN galactokinase deficiency pathway; galactose metabolic pathway; galactosemia pathway; ASSOCIATED WITH cataract (ortholog); COVID-19 (ortholog); galactokinase deficiency (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: galactokinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,802,041 - 91,809,357 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,626,754 - 96,634,067 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,708,641 - 69,715,942 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,259,522 - 75,266,578 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,259,522 - 75,269,048 (-)EnsemblpanPan2panpan1.1
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GALK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,802,041 - 91,809,357 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,626,754 - 96,634,067 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,708,641 - 69,715,942 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,259,522 - 75,266,578 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,259,522 - 75,269,048 (-)EnsemblpanPan2panpan1.1
GALK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,751,469 - 75,765,192 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,751,470 - 75,765,251 (-)Ensemblhg38GRCh38
GRCh371773,747,550 - 73,761,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,265,613 - 71,272,875 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341771,265,612 - 71,272,875NCBI
Celera1770,344,064 - 70,351,327 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,178,882 - 69,186,794 (-)NCBIHuRef
CHM1_11773,819,092 - 73,826,355 (-)NCBICHM1_1
T2T-CHM13v2.01776,644,690 - 76,658,416 (-)NCBIT2T-CHM13v2.0
Galk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,899,183 - 115,903,545 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,899,283 - 115,903,545 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3811116,008,357 - 116,012,719 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,008,457 - 116,012,719 (-)Ensemblmm10GRCm38
MGSCv3711115,869,671 - 115,874,033 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3611115,824,616 - 115,828,768 (-)NCBIMGSCv36mm8
Celera11127,770,557 - 127,774,921 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
Galk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,742,067 - 101,746,244 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl10101,735,061 - 101,746,258 (-)EnsemblGRCr8
mRatBN7.210101,243,146 - 101,247,323 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,235,994 - 101,247,337 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx10106,304,744 - 106,308,922 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,767,830 - 105,772,008 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,164,097 - 101,168,274 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,560,322 - 104,564,499 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,560,303 - 104,564,480 (-)Ensemblrn6Rnor6.0
Rnor_5.010103,720,860 - 103,725,037 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.410106,116,774 - 106,120,951 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1099,817,279 - 99,821,456 (-)NCBICelera
RGSC_v3.110106,131,278 - 106,135,455 (-)NCBI
Cytogenetic Map10q32.1NCBI
Galk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,489,800 - 6,493,354 (+)Ensembl
ChiLan1.0NW_0049555066,489,799 - 6,493,354 (+)NCBIChiLan1.0ChiLan1.0
GALK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,818,558 - 4,824,845 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,805,650 - 4,833,503 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha95,498,590 - 5,504,867 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.095,488,855 - 5,495,207 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,476,066 - 5,495,203 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,528,367 - 5,534,647 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,638,418 - 5,644,788 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,699,320 - 5,705,604 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Galk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,462,160 - 5,467,023 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594944,944 - 949,838 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936594944,936 - 950,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GALK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,642,025 - 5,651,183 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1125,642,012 - 5,651,186 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,588,391 - 5,597,565 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GALK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,919,316 - 45,926,423 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,919,402 - 45,926,304 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607716,676,036 - 16,683,632 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Galk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,646,239 - 5,650,214 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248015,646,112 - 5,649,822 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Galk1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1968,047,335 - 68,051,514 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003813271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000028859   ⟹   ENSPPAP00000006959
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1775,259,522 - 75,266,578 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000028863   ⟹   ENSPPAP00000006962
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1775,259,639 - 75,269,048 (-)Ensembl
RefSeq Acc Id: XM_003813271   ⟹   XP_003813319
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21991,802,041 - 91,809,357 (-)NCBI
NHGRI_mPanPan11796,626,754 - 96,634,067 (-)NCBI
Mhudiblu_PPA_v01769,708,641 - 69,715,942 (-)NCBI
PanPan1.11775,259,522 - 75,266,578 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003813319 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000006959.1
  ENSPPAP00000006962.1
  ENSPPAP00050029565
RefSeq Acc Id: XP_003813319   ⟸   XM_003813271
- UniProtKB: A0A2R8ZR02 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000006962   ⟸   ENSPPAT00000028863
Ensembl Acc Id: ENSPPAP00000006959   ⟸   ENSPPAT00000028859

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000025985 Ensembl, UniProtKB/TrEMBL
  ENSPPAG00050021846 ENTREZGENE
Ensembl Transcript ENSPPAT00000028859.1 UniProtKB/TrEMBL
  ENSPPAT00000028863.1 UniProtKB/TrEMBL
  ENSPPAT00050046088 ENTREZGENE
Gene3D-CATH 3.30.230.10 UniProtKB/TrEMBL
  3.30.70.890 UniProtKB/TrEMBL
InterPro Galactokinase UniProtKB/TrEMBL
  Galactokinase_CS UniProtKB/TrEMBL
  GalKase_N UniProtKB/TrEMBL
  GHMP_kinase_C_dom UniProtKB/TrEMBL
  GHMP_kinase_C_sf UniProtKB/TrEMBL
  GHMP_kinase_N_dom UniProtKB/TrEMBL
  GHMP_knse_ATP-bd_CS UniProtKB/TrEMBL
  Mevalonate/galactokinase UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/TrEMBL
KEGG Report pps:100987312 UniProtKB/TrEMBL
NCBI Gene GALK1 ENTREZGENE
PANTHER GALACTOKINASE-RELATED UniProtKB/TrEMBL
  MEVALONATE KINASE/GALACTOKINASE UniProtKB/TrEMBL
Pfam GalKase_gal_bdg UniProtKB/TrEMBL
  GHMP_kinases_C UniProtKB/TrEMBL
  GHMP_kinases_N UniProtKB/TrEMBL
PIRSF Galactokinase UniProtKB/TrEMBL
PRINTS GALCTOKINASE UniProtKB/TrEMBL
  MEVGALKINASE UniProtKB/TrEMBL
PROSITE GALACTOKINASE UniProtKB/TrEMBL
  GHMP_KINASES_ATP UniProtKB/TrEMBL
Superfamily-SCOP SSF54211 UniProtKB/TrEMBL
  SSF55060 UniProtKB/TrEMBL
UniProt A0A2R8ZR02 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZVN8_PANPA UniProtKB/TrEMBL