LOC100994669 (cytochrome c oxidase assembly factor 8) - Rat Genome Database

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Gene: LOC100994669 (cytochrome c oxidase assembly factor 8) Pan paniscus
Analyze
Symbol: LOC100994669 (Ensembl: COA8)
Name: cytochrome c oxidase assembly factor 8
RGD ID: 11746329
Description: INVOLVED IN intrinsic apoptotic signaling pathway (ortholog); negative regulation of reactive oxygen species biosynthetic process (ortholog); positive regulation of cytochrome-c oxidase activity (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease axonal type 2O (ortholog); cytochrome-c oxidase deficiency disease (ortholog); genetic disease (ortholog); FOUND IN matrix side of mitochondrial inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: APOPT1; apoptogenic 1, mitochondrial; apoptogenic protein 1, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215104,722,238 - 104,750,615 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114103,938,718 - 103,985,710 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01484,189,323 - 84,217,230 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114104,000,696 - 104,027,230 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14104,000,692 - 104,027,230 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100994669
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215104,722,238 - 104,750,615 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114103,938,718 - 103,985,710 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01484,189,323 - 84,217,230 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114104,000,696 - 104,027,230 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14104,000,692 - 104,027,230 (+)Ensemblpanpan1.1panPan2
COA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814103,562,960 - 103,590,899 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14103,562,960 - 103,607,523 (+)EnsemblGRCh38hg38GRCh38
GRCh3714104,029,297 - 104,057,236 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614103,099,084 - 103,128,277 (+)NCBINCBI36Build 36hg18NCBI36
Build 3414103,099,083 - 103,128,261NCBI
Celera1484,083,545 - 84,111,477 (+)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1484,207,680 - 84,235,763 (+)NCBIHuRef
CHM1_114103,967,493 - 103,995,428 (+)NCBICHM1_1
T2T-CHM13v2.01497,799,005 - 97,826,938 (+)NCBIT2T-CHM13v2.0
Coa8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,679,394 - 111,721,491 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,679,695 - 111,721,487 (+)EnsemblGRCm39 Ensembl
GRCm3812111,713,268 - 111,755,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,713,261 - 111,755,053 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712112,951,480 - 112,993,266 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612112,161,079 - 112,181,999 (+)NCBIMGSCv36mm8
Celera12112,907,511 - 112,957,133 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.11NCBI
Coa8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,593,399 - 136,618,237 (+)NCBIGRCr8
mRatBN7.26130,772,218 - 130,797,081 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,771,199 - 130,797,081 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6130,939,429 - 130,964,335 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06131,236,399 - 131,261,305 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06130,602,427 - 130,627,198 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06136,185,772 - 136,210,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.06136,279,476 - 136,304,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,279,496 - 136,304,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,185,487 - 136,210,940 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,205,803 - 144,230,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,495,214 - 136,520,116 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16136,501,406 - 136,526,300 (+)NCBI
Celera6128,327,965 - 128,352,225 (+)NCBICelera
Cytogenetic Map6q32NCBI
Apopt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555382,415,604 - 2,434,658 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555382,415,781 - 2,432,742 (+)NCBIChiLan1.0ChiLan1.0
COA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,324,271 - 71,357,468 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl871,318,244 - 71,357,466 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,836,065 - 70,868,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0871,600,822 - 71,633,185 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl871,600,828 - 71,632,967 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1871,289,897 - 71,322,193 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0871,329,474 - 71,362,251 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,728,858 - 71,761,268 (+)NCBIUU_Cfam_GSD_1.0
APOPT1
(Sus scrofa - pig)
No map positions available.
LOC103229762
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12481,503,069 - 81,533,578 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2481,503,134 - 81,535,430 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605368,807,395 - 68,837,872 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Apopt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247341,293,851 - 1,315,454 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247341,295,053 - 1,315,620 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000023430   ⟹   ENSPPAP00000005130
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14104,000,692 - 104,027,230 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000023433   ⟹   ENSPPAP00000005132
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14104,000,728 - 104,023,854 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000023434   ⟹   ENSPPAP00000005133
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14104,023,823 - 104,027,002 (+)Ensembl
RefSeq Acc Id: XM_003807063   ⟹   XP_003807111
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215104,722,238 - 104,750,615 (+)NCBI
NHGRI_mPanPan114103,938,718 - 103,985,710 (+)NCBI
Mhudiblu_PPA_v01484,189,327 - 84,217,230 (+)NCBI
PanPan1.114104,000,696 - 104,027,230 (+)NCBI
Sequence:
RefSeq Acc Id: XR_008620993
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215104,722,238 - 104,747,053 (+)NCBI
NHGRI_mPanPan114103,938,718 - 103,963,553 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003807111 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005130.1
  ENSPPAP00000005132.1
  ENSPPAP00000005133.1
RefSeq Acc Id: XP_003807111   ⟸   XM_003807063
- UniProtKB: A0A2R8ZMG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000005133   ⟸   ENSPPAT00000023434
Ensembl Acc Id: ENSPPAP00000005132   ⟸   ENSPPAT00000023433
Ensembl Acc Id: ENSPPAP00000005130   ⟸   ENSPPAT00000023430


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000021372 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000023430.1 UniProtKB/TrEMBL
  ENSPPAT00000023433.1 UniProtKB/TrEMBL
  ENSPPAT00000023434.1 UniProtKB/TrEMBL
InterPro COA8 UniProtKB/TrEMBL
NCBI Gene APOPT1 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE ASSEMBLY FACTOR 8 UniProtKB/TrEMBL
  PTHR31107 UniProtKB/TrEMBL
Pfam DUF2315 UniProtKB/TrEMBL
UniProt A0A2R8ZJH4_PANPA UniProtKB/TrEMBL
  A0A2R8ZJJ6_PANPA UniProtKB/TrEMBL
  A0A2R8ZMG2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 LOC100994669  cytochrome c oxidase assembly factor 8  APOPT1  apoptogenic 1, mitochondrial  Symbol and/or name change 5135510 APPROVED