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Gene: ATP6V1G2 (ATPase H+ transporting V1 subunit G2) Pan paniscus

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Symbol:

ATP6V1G2

Name:

ATPase H+ transporting V1 subunit G2

RGD ID:

11733645

Description:

ENCODES a protein that exhibits ATP hydrolysis activity (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN proton transmembrane transport (inferred); synaptic vesicle lumen acidification (inferred); ASSOCIATED WITH megacolon (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN extrinsic component of synaptic vesicle membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

V-type proton ATPase subunit G 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,021,404 - 46,024,447 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	41,982,960 - 41,985,281 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,205,541 - 31,207,930 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,093,006 - 32,097,835 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,095,462 - 32,097,835 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

megacolon (ISO)

proteasome-associated autoinflammatory syndrome 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proton transmembrane transport (IEA)

synaptic vesicle lumen acidification (IEA)

Cellular Component

endomembrane system (IEA)

extrinsic component of synaptic vesicle membrane (ISO)

synaptic vesicle membrane (IEA)

vacuolar proton-transporting V-type ATPase complex (IEA)

vacuolar proton-transporting V-type ATPase, V1 domain (IEA)

Molecular Function

ATP hydrolysis activity (IEA)

protein binding (ISO)

proton-transporting ATPase activity, rotational mechanism (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ATP6V1G2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,021,404 - 46,024,447 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	41,982,960 - 41,985,281 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,205,541 - 31,207,930 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,093,006 - 32,097,835 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,095,462 - 32,097,835 (-)	Ensembl	panpan1.1		panPan2

ATP6V1G2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,544,444 - 31,546,742 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,544,444 - 31,548,427 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,512,221 - 31,514,519 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,620,218 - 31,622,606 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	31,620,217 - 31,622,606	NCBI
Celera	6	33,110,473 - 33,112,857 (-)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,298,970 - 31,301,363 (-)	NCBI		HuRef
CHM1_1	6	31,514,366 - 31,516,759 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,397,536 - 31,399,830 (-)	NCBI		T2T-CHM13v2.0

Atp6v1g2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	35,453,910 - 35,457,743 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	35,452,636 - 35,457,743 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	35,234,931 - 35,238,767 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,233,660 - 35,238,767 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	35,373,541 - 35,375,712 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,844,651 - 34,866,655 (+)	NCBI		MGSCv36	mm8
Celera	17	38,338,746 - 38,340,913 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.6	NCBI

Atp6v1g2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,592,374 - 3,595,986 (-)	NCBI		GRCr8
mRatBN7.2	20	3,587,681 - 3,591,309 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,587,686 - 3,590,481 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,287,681 - 4,289,888 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,649,744 - 3,651,951 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,187,231 - 4,189,452 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	4,821,265 - 4,824,829 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	4,821,285 - 4,823,494 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	6,901,681 - 6,903,894 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	3,626,301 - 3,628,514 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	3,626,543 - 3,628,798 (-)	NCBI
Celera	20	4,435,534 - 4,437,747 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Atp6v1g2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	86,053 - 88,355 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	86,053 - 88,355 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATP6V1G2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,046,109 - 1,049,839 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	1,046,732 - 1,050,103 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,183,323 - 1,184,562 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,191,344 - 1,195,074 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,191,351 - 1,195,091 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,050,915 - 1,052,154 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,118,821 - 1,120,060 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,185,570 - 1,186,809 (-)	NCBI		UU_Cfam_GSD_1.0

Atp6v1g2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,595,220 - 35,597,734 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,963,421 - 1,966,218 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,963,605 - 1,965,727 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP6V1G2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,670,972 - 23,673,837 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,670,970 - 23,673,860 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	27,579,013 - 27,580,146 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP6V1G2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,440,321 - 40,442,701 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	40,440,605 - 40,445,669 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	31,445,699 - 31,448,067 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp6v1g2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	24,651,780 - 24,654,860 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	24,652,156 - 24,654,753 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003831599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008956951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000042107 ⟹ ENSPPAP00000019348

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	6	32,095,462 - 32,097,835 (-)	Ensembl

RefSeq Acc Id:

XM_003831599 ⟹ XP_003831647

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	5	46,021,404 - 46,024,447 (-)	NCBI
NHGRI_mPanPan1	6	41,982,960 - 41,985,142 (-)	NCBI
Mhudiblu_PPA_v0	6	31,205,541 - 31,207,930 (-)	NCBI
PanPan1.1	6	32,095,455 - 32,097,835 (-)	NCBI

Sequence:

show sequence

CTAACCTGTTGTAAGCCCGCAGCTTTGGGCCTAGTCTCTGCTGCTCCCAGGCGGCCCCTTTGGG
TACTGCCTGAGCAAGAAGTGCTGGAGAGGAGGACCAGTCATCAATAGGAGGATGAGATTGGGAG
AGACACTCGGTGCAGGAGGCTGAGTGAGAAGGGGAGCACTAAGACCCAGGGGTAGTGGAGGACT
GCAGCAACGAGCTGGAGGAGGAGAAGTAAGCGGTGGGGGGTGGGAGCCATCTGGTACTTTGACA
GCATTCAAAACAGCATCGGCCATAACAACAGAAATGGCTAGTCAGTCCCAGGGTATCCAGCAGC
TTCTGCAAGCTGAGAAGCGGGCAGCTGAGAAGGTGGCAGATGCCAGAAAGAGGAAGGCCCGGCG
ACTGAAGCAGGCAAAGGAGGAGGCACAGATGGAGGTGGAGCAATACCGCAGAGAGCGAGAGCAC
GAATTCCAGAGCAAGCAGCAGGCGGCCATGGGCTCCCAGGGGAACCTGTCTGCTGAGGTGGAGC
AGGCTACAAGGCGCCAGGTGCAGGGCATGCAGAGCTCCCAGCAAAGAAACCGAGAGCGTGTCCT
GGCCCAGCTTCTTGGCATGGTCTGCGACGTCAGGCCCCAGGTCCACCCCAACTACCGGATTTCT
GCCTAGGGCCACCGTAGGGCCTGACTCCTTCTGCCAGTTCCCTCCCTCAAAGAAATCCTCCAAT
TAAAATCACCTCCCACCATAATCCCTGTCTTCTTTCCATCCCCTAGAAATCCTGGGAGGCAGGA
TCCAATAATTTTCCTGTGACACTTATAAATATCCTGCTCACATCTGAATCTCCTTGTTGTTCTT
TAACCCTCACTGGGACTTTGTAAACTTCCAAGTCATTCTCACCTAAACCCTCTGTGAAATTTGT
AATATGGGGAAGTAGGAATGTGGAAAACATCCTGACTTCAGTGTCTGGCAGATGTGGGTCCCTC
TCTTGACCCTGTCACTTGCTGGCTGTGAAACCAGGACAAGCTACTTAACTTGGTAGCCTCGATG
TCCTCCTCTGTGAAACTGGGATGATAATAATGCCTACCTTGTGAGGGTTGCTTCAATGATTAGG
AATCATTCTGTAAAGTCTAGCACAGTTCCTTGCATGTTGTAGCAGTGATTCAGTAAGTAGCAAC
CCTGTGATACTATTACCACCACCTGCTCACTGGTCAAAACCTACACAGCTGTTTCCTCACGTCC
ATCACTGGCTCTCTAATTCCACTTGTTCATTCTGTGACCCTAGTTATTTTCTGAATAATTGGTT
CTTCTCTTTTCCCAGAGACCTTCTGATCTCCAAAAAGAGGAGATGACTACATTTAGCCCCTCTC
TTATAATTCCAGGTAGATAACTGCGTTTTGTAGCCTCTCTTTGTTTTTCTTTTGCTGATCTTTG
TCTTTATTAGATTTTCCTCCTTTCCTATTTCCCCAAAGACTTATCAGATGCTCATTGCTTTCTA
AGATCTAAAATGATACTGTGTTCCCTCATATGCATGCCCTTCCTTTCTATATCCTTGACACCTT
ACTTTCCCATTGTAACAATAAAAAAAGTATCAATAAAATAATTATCGGCAAATAAA

hide sequence

RefSeq Acc Id:

XM_008956951 ⟹ XP_008955199

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	5	46,021,404 - 46,023,604 (-)	NCBI
NHGRI_mPanPan1	6	41,983,325 - 41,985,281 (-)	NCBI
Mhudiblu_PPA_v0	6	31,205,541 - 31,207,856 (-)	NCBI
PanPan1.1	6	32,095,455 - 32,097,835 (-)	NCBI

Sequence:

show sequence

CTAACCTGTTGTAAGCCCGCAGCTTTGGGCCTAGTCTCTGCTGCTCCCAGGCGGCCCCTTTGGG
TACTGCCTGAGCAAGAAGTGCTGGAGAGGAGGACCAGTCATCAATAGGAGGATGAGATTGGGAG
AGACACTCGGTGCAGGAGGCTGAGTGAGAAGGGGAGCACTAAGACCCAGGGGTAGTGGAGGACT
GCAGCAACGAGCTGGAGGAGGAGAAGGAAGGCCCGGCGACTGAAGCAGGCAAAGGAGGAGGCAC
AGATGGAGGTGGAGCAATACCGCAGAGAGCGAGAGCACGAATTCCAGAGCAAGCAGCAGGCGGC
CATGGGCTCCCAGGGGAACCTGTCTGCTGAGGTGGAGCAGGCTACAAGGCGCCAGGTGCAGGGC
ATGCAGAGCTCCCAGCAAAGAAACCGAGAGCGTGTCCTGGCCCAGCTTCTTGGCATGGTCTGCG
ACGTCAGGCCCCAGGTCCACCCCAACTACCGGATTTCTGCCTAGGGCCACCGTAGGGCCTGACT
CCTTCTGCCAGTTCCCTCCCTCAAAGAAATCCTCCAATTAAAATCACCTCCCACCATAATCCCT
GTCTTCTTTCCATCCCCTAGAAATCCTGGGAGGCAGGATCCAATAATTTTCCTGTGACACTTAT
AAATATCCTGCTCACATCTGAATCTCCTTGTTGTTCTTTAACCCTCACTGGGACTTTGTAAACT
TCCAAGTCATTCTCACCTAAACCCTCTGTGAAATTTGTAATATGGGGAAGTAGGAATGTGGAAA
ACATCCTGACTTCAGTGTCTGGCAGATGTGGGTCCCTCTCTTGACCCTGTCACTTGCTGGCTGT
GAAACCAGGACAAGCTACTTAACTTGGTAGCCTCGATGTCCTCCTCTGTGAAACTGGGATGATA
ATAATGCCTACCTTGTGAGGGTTGCTTCAATGATTAGGAATCATTCTGTAAAGTCTAGCACAGT
TCCTTGCATGTTGTAGCAGTGATTCAGTAAGTAGCAACCCTGTGATACTATTACCACCACCTGC
TCACTGGTCAAAACCTACACAGCTGTTTCCTCACGTCCATCACTGGCTCTCTAATTCCACTTGT
TCATTCTGTGACCCTAGTTATTTTCTGAATAATTGGTTCTTCTCTTTTCCCAGAGACCTTCTGA
TCTCCAAAAAGAGGAGATGACTACATTTAGCCCCTCTCTTATAATTCCAGGTAGATAACTGCGT
TTTGTAGCCTCTCTTTGTTTTTCTTTTGCTGATCTTTGTCTTTATTAGATTTTCCTCCTTTCCT
ATTTCCCCAAAGACTTATCAGATGCTCATTGCTTTCTAAGATCTAAAATGATACTGTGTTCCCT
CATATGCATGCCCTTCCTTTCTATATCCTTGACACCTTACTTTCCCATTGTAACAATAAAAAAA
GTATCAATAAAATAATTATCGGCAAATAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003831647	(Get FASTA)	NCBI Sequence Viewer
	XP_008955199	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000019348
	ENSPPAP00000019348.1

RefSeq Acc Id:	XP_008955199 ⟸ XM_008956951
- Peptide Label:	isoform X2
- Sequence:	show sequence MEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCD VRPQVHPNYRISA hide sequence

RefSeq Acc Id:	XP_003831647 ⟸ XM_003831599
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AQA4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMG SQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA hide sequence

Ensembl Acc Id:

ENSPPAP00000019348 ⟸ ENSPPAT00000042107

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000032852	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000042107.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.2950	UniProtKB/TrEMBL
InterPro	V-ATPase_G	UniProtKB/TrEMBL
KEGG Report	pps:100980405	UniProtKB/TrEMBL
NCBI Gene	ATP6V1G2	ENTREZGENE
PANTHER	PTHR12713	UniProtKB/TrEMBL
	V-TYPE PROTON ATPASE SUBUNIT G 2	UniProtKB/TrEMBL
Pfam	V-ATPase_G	UniProtKB/TrEMBL
UniProt	A0A2R9AQA4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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