TERF1 (telomeric repeat binding factor 1) - Rat Genome Database

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Gene: TERF1 (telomeric repeat binding factor 1) Pan paniscus
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Symbol: TERF1
Name: telomeric repeat binding factor 1
RGD ID: 11690361
Description: ENCODES a protein that exhibits identical protein binding (ortholog); telomerase activity (ortholog); INVOLVED IN meiotic telomere clustering (ortholog); negative regulation of establishment of protein localization to telomere (ortholog); negative regulation of establishment of RNA localization to telomere (ortholog); ASSOCIATED WITH breast cancer (ortholog); squamous cell carcinoma (ortholog); stomach cancer (ortholog); FOUND IN fibrillar center (ortholog); nuclear body (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: telomeric repeat-binding factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2788,753,525 - 88,792,513 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1864,383,202 - 64,422,226 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0869,545,115 - 69,583,997 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1871,192,716 - 71,231,648 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TERF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2788,753,525 - 88,792,513 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1864,383,202 - 64,422,226 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0869,545,115 - 69,583,997 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1871,192,716 - 71,231,648 (+)NCBIpanpan1.1PanPan1.1panPan2
TERF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38873,008,864 - 73,048,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl873,008,856 - 73,048,123 (+)EnsemblGRCh38hg38GRCh38
GRCh37873,921,099 - 73,960,358 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36874,083,661 - 74,122,281 (+)NCBINCBI36Build 36hg18NCBI36
Build 34874,083,662 - 74,122,281NCBI
Celera869,918,262 - 69,957,163 (+)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef869,411,980 - 69,450,876 (+)NCBIHuRef
CHM1_1873,973,943 - 74,012,842 (+)NCBICHM1_1
T2T-CHM13v2.0873,437,901 - 73,477,172 (+)NCBIT2T-CHM13v2.0
Terf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,875,634 - 15,914,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,875,870 - 15,914,276 (+)EnsemblGRCm39 Ensembl
GRCm38115,805,546 - 15,844,052 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,805,646 - 15,844,052 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,795,739 - 15,833,510 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,790,872 - 15,828,643 (+)NCBIMGSCv36mm8
Celera115,750,793 - 15,788,563 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.88NCBI
Terf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr858,226,345 - 8,255,614 (-)NCBIGRCr8
mRatBN7.253,443,103 - 3,472,377 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl53,443,106 - 3,472,340 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx55,560,595 - 5,589,792 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.057,199,479 - 7,228,676 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.056,896,804 - 6,926,212 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,853,455 - 2,882,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl52,853,459 - 2,882,668 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.052,843,150 - 2,872,418 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.452,556,918 - 2,586,086 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.152,556,917 - 2,586,086 (-)NCBI
Celera53,039,138 - 3,068,345 (-)NCBICelera
Cytogenetic Map5q11NCBI
Terf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554447,103,552 - 7,150,323 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554447,103,282 - 7,149,450 (-)NCBIChiLan1.0ChiLan1.0
TERF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,664,378 - 21,701,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,664,186 - 21,700,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,929,296 - 21,966,341 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02921,773,860 - 21,811,415 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2921,773,883 - 21,811,414 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12921,832,463 - 21,869,553 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02921,868,610 - 21,906,117 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02922,149,876 - 22,187,001 (+)NCBIUU_Cfam_GSD_1.0
Terf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530357,612,694 - 57,639,199 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366481,809,395 - 1,835,890 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TERF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl462,797,000 - 62,831,454 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1462,797,244 - 62,831,459 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2468,341,702 - 68,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TERF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1868,608,830 - 68,647,220 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl868,608,844 - 68,648,171 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603972,734,995 - 72,774,562 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Terf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474418,121,687 - 18,156,989 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474418,120,677 - 18,156,920 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_008956694   ⟹   XP_008954942
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2788,753,527 - 88,792,513 (+)NCBI
NHGRI_mPanPan1864,383,204 - 64,422,226 (+)NCBI
Mhudiblu_PPA_v0869,545,115 - 69,583,997 (+)NCBI
PanPan1.1871,192,716 - 71,231,538 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014345953   ⟹   XP_014201439
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2788,753,525 - 88,792,513 (+)NCBI
NHGRI_mPanPan1864,383,202 - 64,422,226 (+)NCBI
Mhudiblu_PPA_v0869,545,115 - 69,583,997 (+)NCBI
PanPan1.1871,192,716 - 71,231,529 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008954942 (Get FASTA)   NCBI Sequence Viewer  
  XP_014201439 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027633.1
  ENSPPAP00000027636.1
RefSeq Acc Id: XP_008954942   ⟸   XM_008956694
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BDB3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014201439   ⟸   XM_014345953
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BH77 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
HTH myb-type   Myb-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036878 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050475.1 UniProtKB/TrEMBL
  ENSPPAT00000050478.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
  Telomere repeat-binding factor, dimerisation domain UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Myb_dom UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  Telomere_rpt-bd_fac_dimer_dom UniProtKB/TrEMBL
  Telomere_rpt-bd_fac_dimer_sf UniProtKB/TrEMBL
  TERF1/2 UniProtKB/TrEMBL
  TRBD-Containing_Protein UniProtKB/TrEMBL
NCBI Gene TERF1 ENTREZGENE
PANTHER TELOMERIC REPEAT-BINDING FACTOR 1 UniProtKB/TrEMBL
  TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 UniProtKB/TrEMBL
Pfam Myb_DNA-binding UniProtKB/TrEMBL
  TRF UniProtKB/TrEMBL
PIRSF Telomere_bd-1_Pin2 UniProtKB/TrEMBL
PROSITE HTH_MYB UniProtKB/TrEMBL
  MYB_LIKE UniProtKB/TrEMBL
SMART SANT UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain-like UniProtKB/TrEMBL
  Telomeric repeat binding factor (TRF) dimerisation domain UniProtKB/TrEMBL
UniProt A0A2R9BDB3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BH77 ENTREZGENE, UniProtKB/TrEMBL