ADAM30 (ADAM metallopeptidase domain 30) - Rat Genome Database

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Gene: ADAM30 (ADAM metallopeptidase domain 30) Pan paniscus
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Symbol: ADAM30
Name: ADAM metallopeptidase domain 30
RGD ID: 11682278
Description: ENCODES a protein that exhibits metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN male gonad development (inferred); proteolysis (inferred); ASSOCIATED WITH Hajdu-Cheney syndrome (ortholog); PHGDH deficiency (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: disintegrin and metalloproteinase domain-containing protein 30
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21112,535,910 - 112,542,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11112,138,361 - 112,144,504 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0182,630,734 - 82,633,448 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11117,628,391 - 117,631,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,628,573 - 117,631,026 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAM30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21112,535,910 - 112,542,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11112,138,361 - 112,144,504 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0182,630,734 - 82,633,448 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11117,628,391 - 117,631,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,628,573 - 117,631,026 (+)Ensemblpanpan1.1panPan2
ADAM30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381119,893,533 - 119,896,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1119,893,533 - 119,896,515 (-)EnsemblGRCh38hg38GRCh38
GRCh371120,436,156 - 120,439,138 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,237,679 - 120,240,636 (-)NCBINCBI36Build 36hg18NCBI36
Build 341120,148,198 - 120,151,155NCBI
Celera1118,666,878 - 118,669,835 (-)NCBICelera
Cytogenetic Map1p12ENTREZGENE
HuRef1118,294,693 - 118,297,684 (-)NCBIHuRef
CHM1_11120,551,650 - 120,554,641 (-)NCBICHM1_1
T2T-CHM13v2.01119,906,790 - 119,909,772 (-)NCBIT2T-CHM13v2.0
Adam30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39398,067,950 - 98,071,485 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl398,067,946 - 98,071,485 (+)EnsemblGRCm39 Ensembl
GRCm38398,160,634 - 98,164,169 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl398,160,630 - 98,164,169 (+)EnsemblGRCm38mm10GRCm38
MGSCv37397,964,735 - 97,967,096 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36398,246,217 - 98,248,578 (+)NCBIMGSCv36mm8
Celera399,560,033 - 99,562,394 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map342.63NCBI
Adam30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82188,440,918 - 188,444,358 (+)NCBIGRCr8
mRatBN7.22185,752,183 - 185,755,623 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2185,752,072 - 185,755,599 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2193,400,568 - 193,404,009 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02191,208,751 - 191,212,192 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02186,033,146 - 186,036,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02200,328,498 - 200,331,938 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,328,387 - 200,331,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02219,804,507 - 219,807,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,997,466 - 193,000,906 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2178,242,634 - 178,246,074 (+)NCBICelera
Cytogenetic Map2q34NCBI
LOC100682600
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11756,768,324 - 56,772,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1756,399,802 - 56,401,549 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01757,649,632 - 57,651,326 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11756,686,190 - 56,687,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01756,711,459 - 56,713,150 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01757,328,617 - 57,330,326 (-)NCBIUU_Cfam_GSD_1.0
Adam30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050582,557,503 - 2,560,461 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936872578,616 - 580,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAM30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4101,314,710 - 101,316,893 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14101,314,710 - 101,316,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24111,215,977 - 111,218,587 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAM30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12013,887,509 - 13,890,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2013,887,666 - 13,890,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603816,517,240 - 16,520,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003806308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000036156   ⟹   ENSPPAP00000013484
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1117,628,573 - 117,631,026 (+)Ensembl
RefSeq Acc Id: XM_003806308   ⟹   XP_003806356
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21112,535,910 - 112,542,053 (-)NCBI
NHGRI_mPanPan11112,138,361 - 112,144,504 (-)NCBI
Mhudiblu_PPA_v0182,630,734 - 82,633,448 (+)NCBI
PanPan1.11117,628,391 - 117,631,178 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003806356 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013484.1
RefSeq Acc Id: XP_003806356   ⟸   XM_003806308
- UniProtKB: A0A2R9A885 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000013484   ⟸   ENSPPAT00000036156
Protein Domains
Disintegrin   EGF-like   Peptidase M12B


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029925 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036156.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  Disintegrin_CS UniProtKB/TrEMBL
  Disintegrin_dom UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/TrEMBL
NCBI Gene ADAM30 ENTREZGENE
PANTHER ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN UniProtKB/TrEMBL
  DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 UniProtKB/TrEMBL
Pfam ADAM_CR UniProtKB/TrEMBL
  Disintegrin UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
PRINTS DISINTEGRIN UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  DISINTEGRIN_1 UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  DISIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF57552 UniProtKB/TrEMBL
UniProt A0A2R9A885 ENTREZGENE, UniProtKB/TrEMBL