Gapdhl3 (glyceraldehyde-3-phosphate dehydrogenase like 3) - Rat Genome Database

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Gene: Gapdhl3 (glyceraldehyde-3-phosphate dehydrogenase like 3) Rattus norvegicus
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Symbol: Gapdhl3
Name: glyceraldehyde-3-phosphate dehydrogenase like 3
RGD ID: 11498208
Description: Predicted to enable adenyl nucleotide binding activity; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; and transferase activity. Predicted to be involved in several processes, including glucose metabolic process; glycolytic process; and regulation of translation. Predicted to be located in cytoskeleton; cytosol; and nucleus; PARTICIPATES IN Alzheimer's disease pathway; gluconeogenesis pathway; glycolysis pathway; .
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glyceraldehyde-3-phosphate dehydrogenase-like; LOC108352954; LOC306115; RGD1560797; similar to glyceraldehyde-3-phosphate dehydrogenase; uncharacterized LOC108352954
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81583,731,940 - 83,879,072 (-)NCBIGRCr8
mRatBN7.21577,324,675 - 77,471,131 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01585,127,370 - 85,156,092 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01588,855,571 - 88,922,715 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41584,510,642 - 84,531,047 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1576,679,384 - 76,707,054 (-)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoskeleton  (IEA)
cytosol  (IEA)
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gapdhl3
770 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)155559608995018120Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157369051895018228Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)155559608991365858Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)157369065795018120Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
1581555Eae19Experimental allergic encephalomyelitis QTL 194.7nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)157630609990088744Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_039093965   ⟹   XP_038949893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81583,848,909 - 83,879,072 (-)NCBI
mRatBN7.21577,442,488 - 77,471,131 (-)NCBI
RefSeq Acc Id: XM_039093966   ⟹   XP_038949894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81583,848,909 - 83,874,009 (-)NCBI
mRatBN7.21577,442,488 - 77,465,543 (-)NCBI
RefSeq Acc Id: XR_005494202
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81583,731,940 - 83,879,063 (-)NCBI
mRatBN7.21577,324,675 - 77,471,124 (-)NCBI
RefSeq Acc Id: XR_005494203
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81583,857,618 - 83,879,050 (-)NCBI
mRatBN7.21577,449,709 - 77,471,120 (-)NCBI
RefSeq Acc Id: XR_005494204
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81583,857,305 - 83,879,052 (-)NCBI
mRatBN7.21577,445,471 - 77,471,120 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038949893 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949894 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040878.4
RefSeq Acc Id: XP_038949893   ⟸   XM_039093965
- UniProtKB: A0A8L2QM97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949894   ⟸   XM_039093966
- UniProtKB: A0A8L2QM97 (UniProtKB/TrEMBL)
Protein Domains
Glyceraldehyde 3-phosphate dehydrogenase NAD(P)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-12764 BioCyc
Ensembl Genes ENSRNOG00000018630 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050443.5 UniProtKB/TrEMBL
Gene3D-CATH Dihydrodipicolinate Reductase, domain 2 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro GlycerAld/Erythrose_P_DH UniProtKB/TrEMBL
  GlycerAld_3-P_DH_AS UniProtKB/TrEMBL
  GlycerAld_3-P_DH_cat UniProtKB/TrEMBL
  GlycerAld_3-P_DH_NAD(P)-bd UniProtKB/TrEMBL
  Glyceraldehyde-3-P_DH_1 UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene LOC108352954 ENTREZGENE
PANTHER GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE UniProtKB/TrEMBL
  GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE UniProtKB/TrEMBL
Pfam Gp_dh_C UniProtKB/TrEMBL
  Gp_dh_N UniProtKB/TrEMBL
PhenoGen Gapdhl3 PhenoGen
PIRSF GAP_DH UniProtKB/TrEMBL
PRINTS G3PDHDRGNASE UniProtKB/TrEMBL
PROSITE GAPDH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018630 RatGTEx
RNAcentral URS0000CD00CB RNACentral
SMART Gp_dh_N UniProtKB/TrEMBL
Superfamily-SCOP Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-fold domains UniProtKB/TrEMBL
UniProt A0A8L2QM97 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Gapdhl3  glyceraldehyde-3-phosphate dehydrogenase like 3  LOC108352954  uncharacterized LOC108352954  Symbol and Name Changed 1299863 APPROVED
2021-03-09 LOC108352954  uncharacterized LOC108352954  RGD1560797  similar to glyceraldehyde-3-phosphate dehydrogenase  Data merged from RGD:1560797 737654 PROVISIONAL
2016-08-02 LOC108352954  uncharacterized LOC108352954      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1560797  similar to glyceraldehyde-3-phosphate dehydrogenase   RGD1560797_predicted  similar to glyceraldehyde-3-phosphate dehydrogenase (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560797_predicted  similar to glyceraldehyde-3-phosphate dehydrogenase (predicted)  LOC306115  similar to glyceraldehyde-3-phosphate dehydrogenase  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC306115  similar to glyceraldehyde-3-phosphate dehydrogenase      Symbol and Name status set to provisional 70820 PROVISIONAL