LOC108350036 (uncharacterized LOC108350036) - Rat Genome Database

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Gene: LOC108350036 (uncharacterized LOC108350036) Rattus norvegicus
Analyze
Symbol: LOC108350036
Name: uncharacterized LOC108350036
RGD ID: 11487146
Description:
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acidic leucine-rich nuclear phosphoprotein 32-related protein-like; uncharacterized protein LOC108350036
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82162,820,527 - 162,914,130 (+)NCBIGRCr8
mRatBN7.22160,521,862 - 160,615,536 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2160,521,937 - 160,561,244 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02174,203,732 - 174,296,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2174,203,693 - 174,244,061 (+)EnsemblRnor6.0rn6Rnor6.0
Celera2154,714,291 - 154,806,803 (+)NCBICelera
Cytogenetic Map2q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in LOC108350036
996 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:21
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000073540
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)228484589169504100Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)228484589169504100Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
4 5 5 63 29 30 8 20 8 5 53 33 55 3 28 22

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_017591287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001836762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001836763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001836764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001836765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001839418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001839419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001839427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001839430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000073540   ⟹   ENSRNOP00000064553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2160,521,937 - 160,561,244 (+)Ensembl
Rnor_6.0 Ensembl2174,203,693 - 174,244,061 (+)Ensembl
RefSeq Acc Id: XM_039103720   ⟹   XP_038959648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,914,130 (+)NCBI
mRatBN7.22160,521,911 - 160,615,536 (+)NCBI
RefSeq Acc Id: XM_039103721   ⟹   XP_038959649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,527 - 162,914,130 (+)NCBI
mRatBN7.22160,521,918 - 160,615,536 (+)NCBI
RefSeq Acc Id: XM_063282900   ⟹   XP_063138970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,527 - 162,859,828 (+)NCBI
RefSeq Acc Id: XM_063282901   ⟹   XP_063138971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,871,572 (+)NCBI
RefSeq Acc Id: XM_063282902   ⟹   XP_063138972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,830,570 - 162,859,828 (+)NCBI
RefSeq Acc Id: XR_010064304
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,914,130 (+)NCBI
RefSeq Acc Id: XR_010064305
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,869,236 (+)NCBI
RefSeq Acc Id: XR_010064306
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,880,377 (+)NCBI
RefSeq Acc Id: XR_010064307
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,871,572 (+)NCBI
RefSeq Acc Id: XR_010064308
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82162,820,532 - 162,914,130 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038959648 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959649 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138970 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138971 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138972 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064553.2
Ensembl Acc Id: ENSRNOP00000064553   ⟸   ENSRNOT00000073540
RefSeq Acc Id: XP_038959648   ⟸   XM_039103720
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038959649   ⟸   XM_039103721
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063138970   ⟸   XM_063282900
- Peptide Label: isoform X1
- UniProtKB: M0R593 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138971   ⟸   XM_063282901
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063138972   ⟸   XM_063282902
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R593-F1-model_v2 AlphaFold M0R593 1-272 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-52767 BioCyc
Ensembl Genes ENSRNOG00000046421 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073540.3 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
NCBI Gene LOC108350036 ENTREZGENE
PANTHER GENE 29133-RELATED UniProtKB/TrEMBL
  LEUCINE RICH REPEAT PROTEIN UniProtKB/TrEMBL
PhenoGen LOC108350036 PhenoGen
PROSITE LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046421 RatGTEx
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt M0R593 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-02 LOC108350036  uncharacterized LOC108350036      Symbol and Name status set to provisional 70820 PROVISIONAL