Vdr (vitamin D (1,25-dihydroxyvitamin D3) receptor) - Rat Genome Database

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Gene: Vdr (vitamin D (1,25-dihydroxyvitamin D3) receptor) Mus musculus
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Symbol: Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
RGD ID: 11484
MGI Page MGI
Description: Enables DNA binding activity and nuclear receptor activity. Involved in regulation of calcidiol 1-monooxygenase activity. Acts upstream of or within several processes, including intestinal absorption; mammary gland development; and positive regulation of apoptotic process involved in mammary gland involution. Predicted to be located in several cellular components, including T-tubule; nuclear lumen; and perinuclear region of cytoplasm. Predicted to be part of RNA polymerase II transcription regulator complex; chromatin; and receptor complex. Predicted to be active in nucleus. Predicted to colocalize with caveola. Is expressed in several structures, including alimentary system; metanephros; nervous system; sensory organ; and skeleton. Used to study osteoporosis and rickets. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); lipid storage disease (multiple); melanoma (multiple); and tuberculosis (multiple). Orthologous to human VDR (vitamin D receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1,25-dihydroxyvitamin D3 receptor; Nr; Nr1i1; nuclear receptor subfamily 1 group I member 1; vitamin D receptor; vitamin D3 receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,752,308 - 97,806,177 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,752,306 - 97,808,511 (-)EnsemblGRCm39 Ensembl
GRCm381597,854,427 - 97,908,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,854,425 - 97,910,630 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,684,858 - 97,738,727 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,682,461 - 97,736,330 (-)NCBIMGSCv36mm8
Celera1599,981,938 - 100,035,599 (-)NCBICelera
Cytogenetic Map15F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acquired immunodeficiency syndrome  (ISO)
Acute Hepatitis  (IEP)
Addison's disease  (ISO)
alopecia  (IMP,ISO)
amyotrophic lateral sclerosis  (ISO)
aortic valve stenosis  (ISO)
asthma  (ISO)
atherosclerosis  (IMP)
atopic dermatitis  (ISO)
autism spectrum disorder  (ISO)
autoimmune hepatitis  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2B  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
Barrett's esophagus  (ISO)
basal cell carcinoma  (ISO)
Behcet's disease  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
bronchopulmonary dysplasia  (ISO)
cholangitis  (ISO)
Chronic Hepatitis C  (ISO)
Chronic Periodontitis  (ISO)
coronary artery disease  (ISO)
Crohn's disease  (ISO)
diabetes mellitus  (ISO)
diabetic retinopathy  (ISO)
disease of cellular proliferation  (ISO)
Dwarfism  (ISO)
erythema nodosum  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Autoimmune Encephalomyelitis  (IDA,IMP)
Experimental Mammary Neoplasms  (IMP)
Fabry disease  (ISO)
familial adenomatous polyposis 2  (ISO)
Familial Hypophosphatemic Rickets  (ISO)
fatty liver disease  (IMP,ISO)
Fetal Growth Retardation  (ISO)
genetic disease  (ISO)
Graves' disease  (ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hypercalciuria  (ISO)
hypertension  (ISO)
Hypophosphatemic Rickets  (ISO)
Inflammation  (ISO)
Insulin Resistance  (IMP)
Intervertebral Disc Displacement  (ISO)
Knee Osteoarthritis  (ISO)
Lead Poisoning  (ISO)
leishmaniasis  (IMP)
lepromatous leprosy  (ISO)
liver cirrhosis  (IMP,ISO)
male breast cancer  (ISO)
melanoma  (ISO)
multiple sclerosis  (ISO)
Myocardial Reperfusion Injury  (IEP)
myopia  (ISO)
Neoplasm Metastasis  (ISO)
non-alcoholic fatty liver disease  (IEP,IMP,ISO)
obesity  (ISO)
osteoporosis  (IAGP,ISO)
otosclerosis  (ISO)
Parathyroid Neoplasms  (ISO)
Parkinson's disease  (ISO)
peptic esophagitis  (ISO)
periodontitis  (ISO)
pneumonia  (IMP,ISO)
polycystic ovary syndrome  (ISO)
Postmenopausal Osteoporosis  (ISO)
primary biliary cholangitis  (ISO)
primary hyperparathyroidism  (ISO)
primary sclerosing cholangitis  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
psoriasis  (ISO)
pulmonary tuberculosis  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (ISO)
rickets  (IAGP,ISO)
secondary hyperparathyroidism  (ISO)
skin melanoma  (ISO)
Spinal Fractures  (ISO)
squamous cell carcinoma  (ISO)
Sunburn  (ISO)
Systemic Inflammatory Response Syndrome  (ISO)
temporal lobe epilepsy  (ISO)
transitional cell carcinoma  (ISO)
tuberculoid leprosy  (ISO)
tuberculosis  (ISO)
Turner syndrome  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
uremia  (ISO)
Urinary Calculi  (ISO)
Viral Bronchiolitis  (ISO)
Vitamin D Deficiency  (ISO)
vitamin D-dependent rickets  (ISO)
vitamin D-dependent rickets type 2A  (IMP,ISO)
vitiligo  (ISO)
Weight Gain  (IMP,ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(R)-noradrenaline  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
24,25-Dihydroxyvitamin D  (EXP,ISO)
3,7-dihydropurine-6-thione  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methoxytyramine  (ISO)
3-oxo-5beta-cholanic acid  (ISO)
3-phenoxybenzoic acid  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acetylsalicylic acid  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
alendronic acid  (ISO)
alfacalcidol  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-linolenic acid  (ISO)
alpha-naphthoflavone  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
bafilomycin A1  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
bezafibrate  (ISO)
biphenyl-2-ol  (ISO)
bisdemethoxycurcumin  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcidiol  (EXP,ISO)
calciol  (EXP,ISO)
calcipotriol  (ISO)
calcitriol  (EXP,ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
captopril  (EXP)
carbon nanotube  (EXP)
carnosic acid  (ISO)
cefalotin  (EXP)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chloroacetaldehyde  (ISO)
cholanic acid  (EXP,ISO)
cholesterol  (ISO)
cholic acid  (ISO)
chromium(6+)  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
estriol  (ISO)
etoposide  (ISO)
eugenol  (ISO)
Falecalcitriol  (ISO)
fenvalerate  (ISO)
flucythrinate  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
gamma-tocopherol  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
glycitein  (ISO)
Goe 6976  (EXP,ISO)
guggulsterone  (EXP)
GW 501516  (ISO)
hexachlorobenzene  (EXP)
homovanillic acid  (ISO)
idarubicin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isopentenyl diphosphate  (ISO)
kaempferol  (ISO)
ketoconazole  (ISO)
lacidipine  (ISO)
lactacystin  (ISO)
lamivudine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP,ISO)
LY294002  (ISO)
manidipine  (ISO)
Maxacalcitol  (ISO)
medroxyprogesterone acetate  (ISO)
mercaptopurine  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methoxsalen  (ISO)
methyl beta-cyclodextrin  (ISO)
methylseleninic acid  (ISO)
N-nitrosodiethylamine  (EXP)
neomycin  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
paricalcitol  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenothrin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
prednisone  (ISO)
promegestone  (ISO)
propanal  (ISO)
purine-6-thiol  (ISO)
pyridaben  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
saracatinib  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium atom  (EXP)
sotorasib  (ISO)
staurosporine  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
superoxide  (EXP)
suramin  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
tocopherol  (ISO)
trametinib  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (EXP)
uranium atom  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin D  (EXP,ISO)
warfarin  (ISO)
zidovudine  (EXP)
zinc atom  (ISO)
zinc protoporphyrin  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (IMP)
apoptotic process involved in mammary gland involution  (IMP)
apoptotic signaling pathway  (ISO)
bile acid signaling pathway  (ISO)
calcium ion transport  (IMP)
cell differentiation  (IBA)
cell morphogenesis  (ISO)
cellular response to amyloid-beta  (ISO)
cellular response to vitamin D  (ISO)
decidualization  (ISO)
heart development  (ISO)
intestinal absorption  (IMP)
intracellular calcium ion homeostasis  (IMP)
lactation  (IMP)
mammary gland branching involved in pregnancy  (IMP)
mRNA transcription by RNA polymerase II  (ISO)
negative regulation of bone trabecula formation  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of keratinocyte proliferation  (ISO)
negative regulation of ossification  (ISO)
negative regulation of transcription by RNA polymerase II  (IBA,ISO)
phosphate ion transmembrane transport  (ISO)
positive regulation of apoptotic process involved in mammary gland involution  (IMP)
positive regulation of bone mineralization  (NAS)
positive regulation of gene expression  (ISO)
positive regulation of keratinocyte differentiation  (ISO)
positive regulation of parathyroid hormone secretion  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,ISO)
positive regulation of vitamin D 24-hydroxylase activity  (ISO)
positive regulation of vitamin D receptor signaling pathway  (ISO)
regulation of calcidiol 1-monooxygenase activity  (IMP)
regulation of calcium ion transport  (ISO)
regulation of DNA-templated transcription  (IDA)
response to bile acid  (ISO)
response to calcium ion  (ISO)
response to estradiol  (ISO)
skeletal system development  (IMP)
vitamin D receptor signaling pathway  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood homeostasis  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal chondrocyte morphology  (IAGP)
abnormal coat/ hair morphology  (IAGP)
abnormal colon morphology  (IAGP)
abnormal cytokine level  (IAGP)
abnormal dendritic cell differentiation  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal epidermis stratum granulosum morphology  (IAGP)
abnormal epiphyseal plate morphology  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal fat-soluble vitamin level  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal femur morphology  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal fibula morphology  (IAGP)
abnormal gametogenesis  (IAGP)
abnormal glucose tolerance  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal interleukin level  (IAGP)
abnormal interleukin-1 secretion  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal intestinal mucosa morphology  (IAGP)
abnormal large intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal long bone hypertrophic chondrocyte zone  (IAGP)
abnormal long bone metaphysis morphology  (IAGP)
abnormal lymph node cell ratio  (IAGP)
abnormal macrophage chemotaxis  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal mineral homeostasis  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal nitric oxide homeostasis  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal renin activity  (IAGP)
abnormal response to new environment  (IAGP)
abnormal response to vitamins  (IAGP)
abnormal skeleton physiology  (IAGP)
abnormal skin development  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal startle reflex  (IAGP)
abnormal T cell number  (IAGP)
abnormal thymus corticomedullary boundary morphology  (IAGP)
abnormal thymus involution  (IAGP)
abnormal tibia morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal tumor necrosis factor level  (IAGP)
abnormal urine homeostasis  (IAGP)
abnormal vitamin D level  (IAGP)
absent mature ovarian follicles  (IAGP)
absent spleen white pulp  (IAGP)
alopecia  (IAGP)
anemia  (IAGP)
asthenozoospermia  (IAGP)
cardiac fibrosis  (IAGP)
cardiac hypertrophy  (IAGP)
colitis  (IAGP)
decreased angiogenesis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone mineral density of femur  (IAGP)
decreased bone resorption  (IAGP)
decreased circulating calcium level  (IAGP)
decreased circulating phosphate level  (IAGP)
decreased compact bone thickness  (IAGP)
decreased hair follicle cell proliferation  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased intestinal calcium absorption  (IAGP)
decreased locomotor activity  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased mean systemic arterial blood pressure  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased prepulse inhibition  (IAGP)
decreased regulatory T cell number  (IAGP)
decreased splenocyte proliferation  (IAGP)
decreased susceptibility to autoimmune diabetes  (IAGP)
decreased susceptibility to parasitic infection  (IAGP)
decreased systemic arterial diastolic blood pressure  (IAGP)
decreased systemic arterial systolic blood pressure  (IAGP)
decreased T cell proliferation  (IAGP)
decreased uterus weight  (IAGP)
decreased vertical activity  (IAGP)
delayed endochondral bone ossification  (IAGP)
dermal cyst  (IAGP)
dermatitis  (IAGP)
dilated hair follicle  (IAGP)
dilated seminiferous tubule  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
ear inflammation  (IAGP)
enlarged mesenteric lymph nodes  (IAGP)
enlarged myocardial fiber  (IAGP)
enlarged parathyroid gland  (IAGP)
enlarged spleen  (IAGP)
epidermal cyst  (IAGP)
female infertility  (IAGP)
flat face  (IAGP)
hypertension  (IAGP)
impaired coordination  (IAGP)
increased activity of parathyroid  (IAGP)
increased bone mass  (IAGP)
increased bone mineral density  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased circulating angiotensin II level  (IAGP)
increased circulating angiotensinogen level  (IAGP)
increased circulating atrial natriuretic factor  (IAGP)
increased circulating follicle stimulating hormone level  (IAGP)
increased circulating luteinizing hormone level  (IAGP)
increased circulating parathyroid hormone level  (IAGP)
increased circulating phosphate level  (IAGP)
increased circulating renin level  (IAGP)
increased fluid intake  (IAGP)
increased heart weight  (IAGP)
increased left ventricle weight  (IAGP)
increased long bone epiphyseal plate size  (IAGP)
increased macrophage cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased osteoblast cell number  (IAGP)
increased osteoid volume  (IAGP)
increased renin activity  (IAGP)
increased sensitivity to xenobiotic induced morbidity/mortality  (IAGP)
increased spleen red pulp amount  (IAGP)
increased susceptibility to autoimmune diabetes  (IAGP)
increased susceptibility to induced colitis  (IAGP)
increased systemic arterial diastolic blood pressure  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased T cell apoptosis  (IAGP)
increased testis weight  (IAGP)
increased thymus weight  (IAGP)
increased trabecular bone volume  (IAGP)
increased urine calcium level  (IAGP)
increased urine potassium level  (IAGP)
increased urine sodium level  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
intestinal inflammation  (IAGP)
intestinal ulcer  (IAGP)
male infertility  (IAGP)
mixed cellular infiltration to dermis  (IAGP)
oligozoospermia  (IAGP)
parathyroid gland hyperplasia  (IAGP)
polyuria  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
rectal prolapse  (IAGP)
reduced female fertility  (IAGP)
reduced male fertility  (IAGP)
rickets  (IAGP)
short femur  (IAGP)
short snout  (IAGP)
short stride length  (IAGP)
short tibia  (IAGP)
slow postnatal weight gain  (IAGP)
sparse vibrissae  (IAGP)
thick interventricular septum  (IAGP)
thick ventricular wall  (IAGP)
thymus hyperplasia  (IAGP)
thymus hypoplasia  (IAGP)
uterus hypoplasia  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk. Abbas S, etal., Breast Cancer Res. 2008;10(2):R31. doi: 10.1186/bcr1994. Epub 2008 Apr 17.
2. Vitamin D receptor gene methylation in hepatocellular carcinoma. Abdalla M, etal., Gene. 2018 May 5;653:65-71. doi: 10.1016/j.gene.2018.02.024. Epub 2018 Feb 9.
3. Vitamin D receptor (VDR) gene SNPs influence VDR expression and modulate protection from multiple sclerosis in HLA-DRB1*15-positive individuals. Agliardi C, etal., Brain Behav Immun. 2011 Jun 12.
4. MicroRNA signatures predict dysregulated vitamin D receptor and calcium pathways status in limb girdle muscle dystrophies (LGMD) 2A/2B. Aguennouz M, etal., Cell Biochem Funct. 2016 Aug;34(6):414-22. doi: 10.1002/cbf.3202.
5. Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. Ahn J, etal., Carcinogenesis. 2009 May;30(5):769-76. Epub 2009 Mar 2.
6. The Association of Vitamin D Receptor Polymorphisms with Multiple Sclerosis in a Case-Control Study from Kuwait. Al-Temaimi RA, etal., PLoS One. 2015 Nov 5;10(11):e0142265. doi: 10.1371/journal.pone.0142265. eCollection 2015.
7. 5' regulatory and 3' untranslated region polymorphisms of vitamin D receptor gene in south Indian HIV and HIV-TB patients. Alagarasu K, etal., J Clin Immunol. 2009 Mar;29(2):196-204. Epub 2008 Aug 20.
8. Association of vitamin D receptor gene start codon (Fok1) polymorphism with high myopia. Annamaneni S, etal., Oman J Ophthalmol. 2011 May;4(2):57-62. doi: 10.4103/0974-620X.83654.
9. Association of vitamin D levels and vitamin D-related gene polymorphisms with liver fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease. Arai T, etal., Dig Liver Dis. 2019 Jan 9. pii: S1590-8658(19)30003-9. doi: 10.1016/j.dld.2018.12.022.
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PMID:19052561   PMID:19088060   PMID:19095793   PMID:19141646   PMID:19176352   PMID:19197242   PMID:19254681   PMID:19269787   PMID:19344698   PMID:19429446   PMID:19500727   PMID:19549793  
PMID:19622632   PMID:19631778   PMID:19692484   PMID:19896660   PMID:19897601   PMID:19924301   PMID:19931640   PMID:19944755   PMID:19948844   PMID:19951695   PMID:19968565   PMID:19995948  
PMID:20051486   PMID:20059953   PMID:20171278   PMID:20194632   PMID:20211142   PMID:20211253   PMID:20214989   PMID:20227497   PMID:20301229   PMID:20347977   PMID:20378820   PMID:20398752  
PMID:20412781   PMID:20458748   PMID:20566739   PMID:20664059   PMID:20813899   PMID:20932939   PMID:21190957   PMID:21191070   PMID:21267068   PMID:21270396   PMID:21298063   PMID:21300024  
PMID:21328347   PMID:21386911   PMID:21424540   PMID:21471213   PMID:21482732   PMID:21601024   PMID:21637996   PMID:21677750   PMID:21697289   PMID:21746882   PMID:21769914   PMID:21814234  
PMID:21832078   PMID:21836023   PMID:21840998   PMID:21850575   PMID:21858154   PMID:21868377   PMID:21873635   PMID:21947295   PMID:21948983   PMID:21952242   PMID:21982773   PMID:22008469  
PMID:22028889   PMID:22034957   PMID:22169009   PMID:22207345   PMID:22242171   PMID:22278022   PMID:22294750   PMID:22319626   PMID:22495177   PMID:22523068   PMID:22537547   PMID:22589201  
PMID:22592802   PMID:22638071   PMID:22647636   PMID:22647968   PMID:22648952   PMID:22670054   PMID:22791341   PMID:22854622   PMID:22896638   PMID:22932118   PMID:22948213   PMID:22962257  
PMID:22988430   PMID:23026511   PMID:23041070   PMID:23112173   PMID:23123403   PMID:23132743   PMID:23188491   PMID:23201171   PMID:23240054   PMID:23389957   PMID:23436936   PMID:23439304  
PMID:23470620   PMID:23585425   PMID:23644099   PMID:23671281   PMID:23696511   PMID:23784946   PMID:23850520   PMID:23873355   PMID:23895994   PMID:23896121   PMID:23945234   PMID:24196349  
PMID:24202304   PMID:24284821   PMID:24343899   PMID:24349534   PMID:24352045   PMID:24365583   PMID:24434184   PMID:24434283   PMID:24470103   PMID:24502291   PMID:24601885   PMID:24641763  
PMID:24722695   PMID:24797667   PMID:24891508   PMID:24949660   PMID:24952961   PMID:25015343   PMID:25043694   PMID:25053427   PMID:25061117   PMID:25080448   PMID:25139050   PMID:25147982  
PMID:25180455   PMID:25201890   PMID:25259922   PMID:25315967   PMID:25316911   PMID:25339699   PMID:25344836   PMID:25405762   PMID:25406395   PMID:25620699   PMID:25719262   PMID:25815722  
PMID:25837735   PMID:25873367   PMID:25919700   PMID:25961000   PMID:26008979   PMID:26046242   PMID:26065916   PMID:26121239   PMID:26134413   PMID:26159695   PMID:26211511   PMID:26212084  
PMID:26235988   PMID:26319498   PMID:26322890   PMID:26323657   PMID:26340892   PMID:26343449   PMID:26343450   PMID:26348637   PMID:26369613   PMID:26429395   PMID:26429397   PMID:26441239  
PMID:26462119   PMID:26488808   PMID:26504088   PMID:26606857   PMID:26675943   PMID:26690785   PMID:26750596   PMID:26877201   PMID:27174721   PMID:27180929   PMID:27184385   PMID:27283745  
PMID:27328307   PMID:27473111   PMID:27498418   PMID:27526034   PMID:27567005   PMID:27601169   PMID:27693451   PMID:27723756   PMID:27728806   PMID:27820600   PMID:27856242   PMID:27895587  
PMID:27898044   PMID:27932380   PMID:28003380   PMID:28004271   PMID:28025137   PMID:28069388   PMID:28104492   PMID:28115699   PMID:28177161   PMID:28216630   PMID:28303937   PMID:28368514  
PMID:28368538   PMID:28443031   PMID:28472309   PMID:28600880   PMID:28602960   PMID:28635660   PMID:28666969   PMID:28751364   PMID:28765041   PMID:28798354   PMID:28803336   PMID:28808057  
PMID:28887147   PMID:28900153   PMID:28938396   PMID:29074956   PMID:29107736   PMID:29228157   PMID:29255036   PMID:29272316   PMID:29282249   PMID:29444238   PMID:29555976   PMID:29718408  
PMID:29754817   PMID:29787748   PMID:29844206   PMID:29942284   PMID:30074824   PMID:30260469   PMID:30267995   PMID:30273386   PMID:30723466   PMID:30813930   PMID:30864841   PMID:31034649  
PMID:31086057   PMID:31225722   PMID:31278070   PMID:31291246   PMID:31361973   PMID:31381163   PMID:31506976   PMID:31555149   PMID:31636184   PMID:31669589   PMID:31776512   PMID:31866999  
PMID:31875848   PMID:31880094   PMID:31940280   PMID:31945466   PMID:31958633   PMID:31968250   PMID:31981799   PMID:32051143   PMID:32082243   PMID:32213983   PMID:32289320   PMID:32355205  
PMID:32497792   PMID:32520608   PMID:32736700   PMID:32863311   PMID:32882254   PMID:32968066   PMID:32987399   PMID:33045433   PMID:33084400   PMID:33130085   PMID:33217447   PMID:33288743  
PMID:33368246   PMID:33373677   PMID:33418034   PMID:33524369   PMID:33647520   PMID:33782973   PMID:33965570   PMID:34013750   PMID:34043707   PMID:34108685   PMID:34165161   PMID:34304712  
PMID:34330705   PMID:34432556   PMID:34453978   PMID:34603779   PMID:34877816   PMID:34878523   PMID:34953963   PMID:34986435   PMID:35065959   PMID:35082348   PMID:35202799   PMID:35254654  
PMID:35288479   PMID:35338345   PMID:35714079   PMID:35833522   PMID:36280140   PMID:36341456   PMID:36402439   PMID:36434267   PMID:36462760   PMID:36579449   PMID:36583727   PMID:36791055  
PMID:36834927   PMID:36960562   PMID:37056928  


Genomics

Comparative Map Data
Vdr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,752,308 - 97,806,177 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,752,306 - 97,808,511 (-)EnsemblGRCm39 Ensembl
GRCm381597,854,427 - 97,908,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1597,854,425 - 97,910,630 (-)EnsemblGRCm38mm10GRCm38
MGSCv371597,684,858 - 97,738,727 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,682,461 - 97,736,330 (-)NCBIMGSCv36mm8
Celera1599,981,938 - 100,035,599 (-)NCBICelera
Cytogenetic Map15F1NCBI
VDR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,841,537 - 47,904,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1247,841,537 - 47,943,048 (-)EnsemblGRCh38hg38GRCh38
GRCh371248,235,320 - 48,298,777 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,521,587 - 46,585,081 (-)NCBINCBI36Build 36hg18NCBI36
Build 341246,521,588 - 46,585,036NCBI
Celera1247,032,871 - 47,096,518 (-)NCBICelera
Cytogenetic Map12q13.11NCBI
HuRef1245,266,368 - 45,330,677 (-)NCBIHuRef
CHM1_11248,201,212 - 48,264,704 (-)NCBICHM1_1
T2T-CHM13v2.01247,802,918 - 47,866,398 (-)NCBIT2T-CHM13v2.0
Vdr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27128,987,981 - 129,037,677 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7128,987,981 - 129,037,677 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7130,785,124 - 130,834,890 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07133,010,661 - 133,060,429 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07132,923,119 - 132,972,888 (-)NCBIRnor_WKY
Rnor_6.07139,344,452 - 139,394,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,342,063 - 139,394,166 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07139,536,241 - 139,585,928 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,567,614 - 136,617,280 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17136,644,050 - 136,693,717 (-)NCBI
Celera7125,479,125 - 125,528,679 (-)NCBICelera
Cytogenetic Map7q36NCBI
Vdr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,745,678 - 6,798,048 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,745,725 - 6,798,052 (-)NCBIChiLan1.0ChiLan1.0
VDR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11246,198,173 - 46,322,812 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01240,828,413 - 40,891,700 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11241,661,688 - 41,766,192 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,702,742 - 41,766,192 (+)Ensemblpanpan1.1panPan2
VDR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,852,915 - 6,909,466 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,852,723 - 6,909,470 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2739,397,549 - 39,454,181 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0276,920,266 - 6,976,964 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl276,921,548 - 6,976,937 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,857,514 - 6,914,062 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0276,892,693 - 6,949,518 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02739,686,018 - 39,742,660 (-)NCBIUU_Cfam_GSD_1.0
Vdr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,363,831 - 67,424,087 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365125,740,748 - 5,801,109 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365125,741,836 - 5,800,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VDR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl578,205,810 - 78,266,475 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1578,205,807 - 78,266,505 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2581,279,217 - 81,338,475 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VDR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11144,062,198 - 44,126,295 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1144,065,457 - 44,166,684 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037202,254,076 - 202,319,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vdr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248164,365,961 - 4,424,514 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248164,314,146 - 4,423,946 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vdr
1725 total Variants
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir298mmu-miR-298-5pMirtarbaseexternal_infoImmunoblot//Luciferase reporter assayFunctional MTI19581388

Predicted Target Of
Summary Value
Count of predictions:2714
Count of miRNA genes:856
Interacting mature miRNAs:1161
Transcripts:ENSMUST00000023119, ENSMUST00000126568, ENSMUST00000139656, ENSMUST00000173104, ENSMUST00000173611, ENSMUST00000174633
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597697881103008427Mouse

Markers in Region
Vdr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371597,684,866 - 97,685,279UniSTSGRCm37
MGSCv371597,685,152 - 97,685,220UniSTSGRCm37
Celera1599,981,946 - 99,982,359UniSTS
Celera1599,982,232 - 99,982,300UniSTS
Cytogenetic Map15F1UniSTS
cM Map556.0UniSTS
cM Map15 UniSTS
PMC23328P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381597,884,798 - 97,884,926UniSTSGRCm38
MGSCv371597,715,229 - 97,715,357UniSTSGRCm37
Celera15100,012,329 - 100,012,457UniSTS
Cytogenetic Map15F1UniSTS
Vdr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
Vdr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
cM Map556.0UniSTS
cM Map15 UniSTS
Vdr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381597,854,435 - 97,854,848UniSTSGRCm38
MGSCv371597,684,866 - 97,685,279UniSTSGRCm37
Celera1599,981,946 - 99,982,359UniSTS
Cytogenetic Map15F1UniSTS
Vdr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381597,854,721 - 97,854,789UniSTSGRCm38
MGSCv371597,685,152 - 97,685,220UniSTSGRCm37
Celera1599,982,232 - 99,982,300UniSTS
Cytogenetic Map15F1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000023119   ⟹   ENSMUSP00000023119
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,752,306 - 97,806,191 (-)Ensembl
GRCm38.p6 Ensembl1597,854,425 - 97,908,310 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126568   ⟹   ENSMUSP00000116842
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,774,657 - 97,794,694 (-)Ensembl
GRCm38.p6 Ensembl1597,876,776 - 97,896,813 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139656
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,755,418 - 97,757,579 (-)Ensembl
GRCm38.p6 Ensembl1597,857,537 - 97,859,698 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173104   ⟹   ENSMUSP00000134584
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,774,729 - 97,808,511 (-)Ensembl
GRCm38.p6 Ensembl1597,876,848 - 97,910,630 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173611   ⟹   ENSMUSP00000133351
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,782,770 - 97,807,443 (-)Ensembl
GRCm38.p6 Ensembl1597,884,889 - 97,909,562 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174633   ⟹   ENSMUSP00000133682
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1597,782,758 - 97,808,511 (-)Ensembl
GRCm38.p6 Ensembl1597,884,877 - 97,910,630 (-)Ensembl
RefSeq Acc Id: NM_009504   ⟹   NP_033530
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391597,752,308 - 97,806,177 (-)NCBI
GRCm381597,854,427 - 97,908,296 (-)ENTREZGENE
MGSCv371597,684,858 - 97,738,727 (-)RGD
Celera1599,981,938 - 100,035,599 (-)RGD
cM Map15 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033530   ⟸   NM_009504
- UniProtKB: Q922X0 (UniProtKB/Swiss-Prot),   P48281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000116842   ⟸   ENSMUST00000126568
RefSeq Acc Id: ENSMUSP00000133682   ⟸   ENSMUST00000174633
RefSeq Acc Id: ENSMUSP00000023119   ⟸   ENSMUST00000023119
RefSeq Acc Id: ENSMUSP00000133351   ⟸   ENSMUST00000173611
RefSeq Acc Id: ENSMUSP00000134584   ⟸   ENSMUST00000173104
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48281-F1-model_v2 AlphaFold P48281 1-422 view protein structure

Promoters
RGD ID:6826598
Promoter ID:MM_KWN:19583
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000065369
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361597,690,001 - 97,690,501 (-)MPROMDB
RGD ID:6826595
Promoter ID:MM_KWN:19584
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000065368
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361597,726,951 - 97,727,451 (-)MPROMDB
RGD ID:6826597
Promoter ID:MM_KWN:19585
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   Kidney
Transcripts:OTTMUST00000065367
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361597,738,321 - 97,738,821 (-)MPROMDB
RGD ID:8684878
Promoter ID:EPDNEW_M20470
Type:initiation region
Name:Vdr_1
Description:Mus musculus vitamin D (1,25-dihydroxyvitamin D3) receptor ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381597,908,270 - 97,908,330EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103076 AgrOrtholog
Ensembl Genes ENSMUSG00000022479 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023119 ENTREZGENE
  ENSMUSP00000023119.9 UniProtKB/Swiss-Prot
  ENSMUSP00000116842.2 UniProtKB/TrEMBL
  ENSMUSP00000133351.2 UniProtKB/TrEMBL
  ENSMUSP00000133682.2 UniProtKB/TrEMBL
  ENSMUSP00000134584.3 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023119 ENTREZGENE
  ENSMUST00000023119.15 UniProtKB/Swiss-Prot
  ENSMUST00000126568.8 UniProtKB/TrEMBL
  ENSMUST00000173104.8 UniProtKB/TrEMBL
  ENSMUST00000173611.2 UniProtKB/TrEMBL
  ENSMUST00000174633.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DBD_VDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VitD_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22337 UniProtKB/Swiss-Prot
MGD MGI:103076 ENTREZGENE
NCBI Gene 22337 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VITAMIN D3 RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB VDR RGD
PhenoGen Vdr PhenoGen
PRINTS STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VITAMINDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z3H9_MOUSE UniProtKB/TrEMBL
  G3UWM9_MOUSE UniProtKB/TrEMBL
  G3UXG5_MOUSE UniProtKB/TrEMBL
  G3UZP9_MOUSE UniProtKB/TrEMBL
  P48281 ENTREZGENE
  Q3U0J7_MOUSE UniProtKB/TrEMBL
  Q4FJV8_MOUSE UniProtKB/TrEMBL
  Q922X0 ENTREZGENE
  VDR_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q922X0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-09 Vdr  vitamin D (1,25-dihydroxyvitamin D3) receptor    vitamin D receptor  Symbol and/or name change 5135510 APPROVED