Rpl35al6 (ribosomal protein L35A like 6) - Rat Genome Database

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Gene: Rpl35al6 (ribosomal protein L35A like 6) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl35al6
Name: ribosomal protein L35A like 6
RGD ID: 11430655
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit biogenesis. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L35a pseudogene; 60S ribosomal protein L35a-like; large ribosomal subunit protein eL33-like; LOC108350427
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83112,818,253 - 112,826,585 (+)NCBIGRCr8
mRatBN7.2392,369,741 - 92,370,081 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl392,369,742 - 92,370,074 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0395,939,245 - 95,939,649 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Celera391,420,557 - 91,420,961 (+)NCBICelera
Cytogenetic Map3q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in Rpl35al6
67 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_063284946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041291   ⟹   ENSRNOP00000047759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl392,369,742 - 92,370,074 (+)Ensembl
Rnor_6.0 Ensembl395,939,260 - 95,939,592 (+)Ensembl
RefSeq Acc Id: XM_063284946   ⟹   XP_063141016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83112,818,253 - 112,826,585 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063141016 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000039099.3
  ENSRNOP00000047759
  ENSRNOP00000047759.3
Ensembl Acc Id: ENSRNOP00000047759   ⟸   ENSRNOT00000041291
RefSeq Acc Id: XP_063141016   ⟸   XM_063284946
- UniProtKB: A0A8L2QJQ6 (UniProtKB/TrEMBL),   F1M0T2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M0T2-F1-model_v2 AlphaFold F1M0T2 1-110 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:11430655 AgrOrtholog
BioCyc Gene G2FUF-48518 BioCyc
Ensembl Genes ENSRNOG00000031694 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000070978 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041291 ENTREZGENE
  ENSRNOT00000041291.4 UniProtKB/TrEMBL
  ENSRNOT00000050438.3 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.190 UniProtKB/TrEMBL
InterPro L35A_sf UniProtKB/TrEMBL
  Ribosomal_L35A UniProtKB/TrEMBL
  Ribosomal_L35Ae_CS UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
NCBI Gene LOC108350427 ENTREZGENE
PANTHER PTHR10902 UniProtKB/TrEMBL
Pfam Ribosomal_L35Ae UniProtKB/TrEMBL
PhenoGen Rpl35al6 PhenoGen
PROSITE RIBOSOMAL_L35AE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031694 RatGTEx
  ENSRNOG00000070978 RatGTEx
Superfamily-SCOP SSF50447 UniProtKB/TrEMBL
UniProt A0A8L2QJQ6 ENTREZGENE, UniProtKB/TrEMBL
  F1M0T2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Rpl35al6  ribosomal protein L35A like 6  Rpl35al2  ribosomal protein L35A like 2  Name and Symbol changed 629549 APPROVED
2023-09-19 Rpl35al2  ribosomal protein L35A like 2  LOC108350427  60S ribosomal protein L35a pseudogene  Symbol and Name Changed 1299863 APPROVED
2016-08-02 LOC108350427  60S ribosomal protein L35a pseudogene      Symbol and Name status set to provisional 70820 PROVISIONAL