Th Mouse (+)-catechin multiple interactions ISO Th (Rattus norvegicus) 6480464 Catechin inhibits the reaction [Rotenone results in decreased activity of TH protein] CTD PMID:35337893 Th Mouse (+)-sesamin multiple interactions ISO Th (Rattus norvegicus) 6480464 sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:19794909 Th Mouse (+)-taxifolin multiple interactions ISO Th (Rattus norvegicus) 6480464 taxifolin inhibits the reaction [Rotenone results in decreased activity of TH protein] CTD PMID:35187747 Th Mouse (-)-epigallocatechin 3-gallate decreases expression ISO Th (Rattus norvegicus) 6480464 epigallocatechin gallate results in decreased expression of TH protein CTD PMID:27659729 Th Mouse (-)-selegiline multiple interactions ISO Th (Rattus norvegicus) 6480464 Selegiline inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:16490285 Th Mouse (-)-selegiline decreases expression ISO Th (Rattus norvegicus) 6480464 Selegiline results in decreased expression of TH mRNA CTD PMID:11862330 Th Mouse (R)-adrenaline increases chemical synthesis EXP 6480464 TH protein results in increased chemical synthesis of Epinephrine CTD PMID:9822156 Th Mouse (R)-adrenaline multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in increased expression of TH protein] which results in increased abundance of Epinephrine CTD PMID:19067675 Th Mouse (R)-noradrenaline multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Norepinephrine and [Clonidine results in increased expression of TH protein] which results in increased abundance of Norepinephrine CTD PMID:19067675 Th Mouse (R)-noradrenaline increases chemical synthesis EXP 6480464 TH protein results in increased chemical synthesis of Norepinephrine CTD PMID:9822156 Th Mouse (R,R,R)-alpha-tocopherol multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein and alpha-Tocopherol inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:15790535 and PMID:25891525 Th Mouse (S)-AMPA decreases expression ISO Th (Rattus norvegicus) 6480464 alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein CTD PMID:36775207 Th Mouse (S)-AMPA multiple interactions ISO Th (Rattus norvegicus) 6480464 1-naphthylacetylspermine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein] and aminophenyl fluorescein inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein] CTD PMID:36775207 Th Mouse (S)-amphetamine increases expression EXP 6480464 Dextroamphetamine results in increased expression of TH mRNA CTD PMID:18681898 Th Mouse (S)-naringenin multiple interactions ISO Th (Rattus norvegicus) 6480464 naringenin inhibits the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:34655599 Th Mouse (S)-naringenin decreases expression ISO Th (Rattus norvegicus) 6480464 naringenin results in decreased expression of TH protein CTD PMID:34655599 Th Mouse (S)-nicotine multiple interactions ISO Th (Rattus norvegicus) 6480464 [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]] more ... CTD PMID:29246838 Th Mouse (S)-nicotine increases expression ISO Th (Rattus norvegicus) 6480464 Nicotine results in increased expression of TH mRNA and Nicotine results in increased expression of TH protein CTD PMID:29246838 Th Mouse (S)-nicotine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:19594327 more ... Th Mouse (S)-nicotine multiple interactions ISO TH (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased expression of TH mRNA] CTD PMID:17498763 Th Mouse (S)-nicotine increases expression ISO TH (Homo sapiens) 6480464 Nicotine results in increased expression of TH mRNA and Nicotine results in increased expression of TH protein CTD PMID:17498763 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 (3R)-((2 more ... CTD PMID:16402076 more ... Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:30195017 and PMID:38016618 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO TH (Homo sapiens) 6480464 PRKN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 and PMID:25447324 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:15329391 more ... Th Mouse 1-Naphthylacetylspermine multiple interactions ISO Th (Rattus norvegicus) 6480464 1-naphthylacetylspermine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein] CTD PMID:36775207 Th Mouse 15-deoxy-Delta(12,14)-prostaglandin J2 increases expression ISO Th (Rattus norvegicus) 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 results in increased expression of TH protein CTD PMID:15212945 Th Mouse 17beta-estradiol affects expression ISO Th (Rattus norvegicus) 6480464 Estradiol affects the expression of TH protein CTD PMID:16427766 Th Mouse 17beta-estradiol multiple interactions EXP 6480464 Estradiol inhibits the reaction [manganese chloride results in decreased expression of TH mRNA] and Estradiol inhibits the reaction [manganese chloride results in decreased expression of TH protein] CTD PMID:29183790 Th Mouse 17beta-estradiol increases expression ISO TH (Homo sapiens) 6480464 Estradiol results in increased expression of TH mRNA CTD PMID:27271280 and PMID:31614463 Th Mouse 17beta-estradiol multiple interactions ISO TH (Homo sapiens) 6480464 Estradiol promotes the reaction [ESR2 protein affects the expression of TH mRNA] and Estradiol results in increased expression of and results in increased secretion of TH protein CTD PMID:20404318 and PMID:27271280 Th Mouse 17beta-estradiol affects expression ISO TH (Homo sapiens) 6480464 Estradiol affects the expression of TH mRNA CTD PMID:14699072 Th Mouse 2',5'-Dideoxyadenosine multiple interactions ISO Th (Rattus norvegicus) 6480464 2' and 5'-dideoxyadenosine inhibits the reaction [epibatidine results in increased expression of TH mRNA] CTD PMID:15588622 Th Mouse 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO Th (Rattus norvegicus) 6480464 2 more ... CTD PMID:29233657 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TH protein] more ... CTD PMID:19481886 more ... Th Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Th (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of TH mRNA CTD PMID:22808131 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TH protein CTD PMID:19481886 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TH mRNA and Tetrachlorodibenzodioxin results in increased expression of TH protein CTD PMID:19500377 more ... Th Mouse 2,3,7,8-tetrachlorodibenzodioxine increases activity EXP 6480464 Tetrachlorodibenzodioxin results in increased activity of TH protein CTD PMID:19500377 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases methylation EXP 6480464 Tetrachlorodibenzodioxin results in decreased methylation of TH gene CTD PMID:21212295 Th Mouse 2,4-D increases expression ISO Th (Rattus norvegicus) 6480464 2 and 4-Dichlorophenoxyacetic Acid results in increased expression of TH protein CTD PMID:16931444 Th Mouse 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO Th (Rattus norvegicus) 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the expression of TH protein] CTD PMID:33571554 Th Mouse 3,4-dihydroxyphenylacetaldehyde affects binding ISO Th (Rattus norvegicus) 6480464 3 and 4-dihydroxyphenylacetaldehyde binds to TH protein CTD PMID:21238438 Th Mouse 3,4-dihydroxyphenylacetaldehyde decreases activity ISO Th (Rattus norvegicus) 6480464 3 and 4-dihydroxyphenylacetaldehyde results in decreased activity of TH protein CTD PMID:21514317 Th Mouse 3,4-dihydroxyphenylacetaldehyde multiple interactions ISO Th (Rattus norvegicus) 6480464 [3 and 4-dihydroxyphenylacetaldehyde results in decreased activity of TH protein] which results in decreased chemical synthesis of Levodopa CTD PMID:21514317 Th Mouse 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide multiple interactions EXP 6480464 Raclopride inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:16088948 Th Mouse 3,7-dihydropurine-6-thione multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] and Mercaptopurine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:27435855 Th Mouse 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Th (Rattus norvegicus) 6480464 bisindolylmaleimide I inhibits the reaction [3-(2-hydroxy-4-(1 more ... CTD PMID:18992715 Th Mouse 3-Amino-1-methyl-5H-pyrido[4,3-b]indole decreases activity ISO Th (Rattus norvegicus) 6480464 3-amino-1-methyl-5H-pyrido(4 and 3-b)indole results in decreased activity of TH protein CTD PMID:2904812 Th Mouse 3-hydroxybutyric acid multiple interactions EXP 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]] more ... CTD PMID:36435477 Th Mouse 3-methyladenine multiple interactions ISO Th (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [fenvalerate results in decreased expression of TH protein] and 3-methyladenine inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:28802652 and PMID:31734597 Th Mouse 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:31187328 Th Mouse 4,4'-sulfonyldiphenol increases expression ISO Th (Rattus norvegicus) 6480464 bisphenol S results in increased expression of TH mRNA CTD PMID:26186136 Th Mouse 4,4'-sulfonyldiphenol affects methylation EXP 6480464 bisphenol S affects the methylation of TH exon CTD PMID:33297965 Th Mouse 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of TH mRNA CTD PMID:30951980 Th Mouse 4-phenylbutyric acid increases expression EXP 6480464 4-phenylbutyric acid results in increased expression of TH protein CTD PMID:21372141 Th Mouse 5-(2-chloroethyl)-4-methylthiazole multiple interactions EXP 6480464 Chlormethiazole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:1381816 Th Mouse 5-aza-2'-deoxycytidine increases expression ISO TH (Homo sapiens) 6480464 Decitabine results in increased expression of TH mRNA CTD PMID:23441691 Th Mouse 5-fluorouracil affects expression EXP 6480464 Fluorouracil affects the expression of TH protein CTD PMID:21296659 Th Mouse 6-propyl-2-thiouracil increases expression ISO Th (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of TH mRNA CTD PMID:25825206 Th Mouse 6-propyl-2-thiouracil decreases expression ISO Th (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of TH mRNA CTD PMID:33150595 Th Mouse 6-propyl-2-thiouracil increases methylation ISO Th (Rattus norvegicus) 6480464 Propylthiouracil results in increased methylation of TH promoter CTD PMID:33150595 Th Mouse 7-NITROINDAZOLE multiple interactions EXP 6480464 7-nitroindazole affects the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:8931477 Th Mouse 8-bromo-3',5'-cyclic GMP multiple interactions ISO Th (Rattus norvegicus) 6480464 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] and 8-bromocyclic GMP inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 Th Mouse 9-cis-retinoic acid decreases expression ISO TH (Homo sapiens) 6480464 Alitretinoin results in decreased expression of TH protein CTD PMID:36805303 Th Mouse acetic acid decreases expression EXP 6480464 Acetic Acid results in decreased expression of TH protein CTD PMID:21296659 Th Mouse acetylcholine increases expression ISO Th (Rattus norvegicus) 6480464 Acetylcholine results in increased expression of TH mRNA CTD PMID:29246838 Th Mouse acetylcholine multiple interactions ISO Th (Rattus norvegicus) 6480464 conotoxin AuIB inhibits the reaction [Acetylcholine results in increased expression of TH mRNA] more ... CTD PMID:29246838 Th Mouse acrylamide increases expression ISO Th (Rattus norvegicus) 6480464 Acrylamide results in increased expression of TH mRNA and Acrylamide results in increased expression of TH protein CTD PMID:25943760 Th Mouse acrylonitrile multiple interactions ISO Th (Rattus norvegicus) 6480464 Acrylonitrile inhibits the reaction [3 and 3'-iminodipropionitrile results in increased expression of TH protein] CTD PMID:19244277 Th Mouse aflatoxin B1 increases methylation ISO TH (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of TH intron CTD PMID:30157460 Th Mouse Aflatoxin B2 alpha decreases methylation ISO TH (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of TH polyA tail CTD PMID:30157460 Th Mouse agmatine multiple interactions ISO Th (Rattus norvegicus) 6480464 Agmatine inhibits the reaction [Morphine results in increased expression of TH protein] CTD PMID:15541421 Th Mouse albiflorin affects expression ISO Th (Rattus norvegicus) 6480464 albiflorin affects the expression of TH CTD PMID:26475043 Th Mouse all-trans-retinoic acid multiple interactions ISO TH (Homo sapiens) 6480464 [Tretinoin co-treated with CNTF protein] results in increased expression of TH more ... CTD PMID:17017122 more ... Th Mouse all-trans-retinoic acid decreases expression ISO TH (Homo sapiens) 6480464 Tretinoin results in decreased expression of TH protein CTD PMID:36805303 Th Mouse all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of TH mRNA CTD PMID:34627992 Th Mouse all-trans-retinoic acid multiple interactions EXP 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of TH mRNA and [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TH mRNA CTD PMID:30951980 and PMID:36189433 Th Mouse all-trans-retinoic acid increases expression ISO TH (Homo sapiens) 6480464 Tretinoin results in increased expression of TH mRNA and Tretinoin results in increased expression of TH protein CTD PMID:15464216 more ... Th Mouse AM-251 multiple interactions ISO Th (Rattus norvegicus) 6480464 AM 251 affects the reaction [(3R)-((2 more ... CTD PMID:29113897 Th Mouse amentoflavone multiple interactions EXP 6480464 amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:28185818 Th Mouse aminoguanidine multiple interactions EXP 6480464 pimagedine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein] CTD PMID:20455021 Th Mouse amitraz increases expression ISO Th (Rattus norvegicus) 6480464 amitraz results in increased expression of TH mRNA and amitraz results in increased expression of TH protein CTD PMID:28463726 Th Mouse amitraz multiple interactions ISO Th (Rattus norvegicus) 6480464 Tamoxifen inhibits the reaction [amitraz results in increased expression of TH mRNA] and Tamoxifen inhibits the reaction [amitraz results in increased expression of TH protein] CTD PMID:28463726 Th Mouse amitrole multiple interactions ISO Th (Rattus norvegicus) 6480464 Amitrole promotes the reaction [Sodium Chloride and Dietary results in increased expression of TH protein] CTD PMID:25891026 Th Mouse ammonium chloride affects expression ISO Th (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of TH mRNA CTD PMID:16483693 Th Mouse ammonium chloride decreases expression ISO Th (Rattus norvegicus) 6480464 Ammonium Chloride results in decreased expression of TH protein CTD PMID:16483693 Th Mouse amphetamine increases expression ISO Th (Rattus norvegicus) 6480464 Amphetamine results in increased expression of TH mRNA CTD PMID:16126238 Th Mouse amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of TH mRNA and Amphetamine results in increased expression of TH protein CTD PMID:16916582 and PMID:19059431 Th Mouse amphetamine decreases expression ISO Th (Rattus norvegicus) 6480464 Amphetamine results in decreased expression of TH protein CTD PMID:12468030 more ... Th Mouse amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of TH protein CTD PMID:20620199 Th Mouse amphetamine multiple interactions EXP 6480464 PTN protein inhibits the reaction [Amphetamine results in decreased expression of TH protein] CTD PMID:20620199 Th Mouse apigenin multiple interactions ISO Th (Rattus norvegicus) 6480464 Apigenin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:28389404 Th Mouse apocynin decreases expression ISO Th (Rattus norvegicus) 6480464 acetovanillone results in decreased expression of TH mRNA CTD PMID:25217652 Th Mouse apocynin multiple interactions ISO Th (Rattus norvegicus) 6480464 acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein] CTD PMID:29859868 Th Mouse aprepitant multiple interactions ISO Th (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Aprepitant inhibits the reaction [Rotenone results in decreased expression of TH protein]] and Aprepitant inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:37224993 Th Mouse Aroclor 1254 multiple interactions ISO Th (Rattus norvegicus) 6480464 [aroclor 1242 co-treated with aroclor 1248 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] results in decreased expression of TH protein and [Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1242 co-treated with aroclor 1248] results in decreased expression of TH mRNA CTD PMID:17324953 and PMID:29879404 Th Mouse Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of TH protein CTD PMID:22094459 Th Mouse arsane multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein] CTD PMID:22704994 Th Mouse arsane increases expression EXP 6480464 Arsenic results in increased expression of TH protein CTD PMID:27413109 Th Mouse arsane decreases expression ISO Th (Rattus norvegicus) 6480464 Arsenic results in decreased expression of TH protein CTD PMID:22704994 Th Mouse arsenic atom decreases expression ISO Th (Rattus norvegicus) 6480464 Arsenic results in decreased expression of TH protein CTD PMID:22704994 Th Mouse arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of TH protein CTD PMID:27413109 Th Mouse arsenic atom multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein] CTD PMID:22704994 Th Mouse arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of TH mRNA CTD PMID:33053406 Th Mouse arsenite(3-) decreases expression ISO Th (Rattus norvegicus) 6480464 arsenite results in decreased expression of TH protein CTD PMID:29982692 Th Mouse arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of TH mRNA and arsenite results in decreased expression of TH protein CTD PMID:29982692 and PMID:33053406 Th Mouse arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of TH mRNA CTD PMID:23392890 and PMID:23518225 Th Mouse arsenous acid decreases expression ISO TH (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of TH protein CTD PMID:11027660 Th Mouse arsenous acid multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of TH mRNA] CTD PMID:23392890 Th Mouse Asiaticoside multiple interactions ISO Th (Rattus norvegicus) 6480464 [asiaticoside co-treated with Rotenone] results in decreased expression of TH protein CTD PMID:28238857 Th Mouse atrazine decreases expression ISO Th (Rattus norvegicus) 6480464 Atrazine results in decreased expression of TH mRNA and Atrazine results in decreased expression of TH protein CTD PMID:14550852 more ... Th Mouse atrazine decreases expression ISO TH (Homo sapiens) 6480464 Atrazine results in decreased expression of TH mRNA CTD PMID:34146662 Th Mouse baicalein multiple interactions EXP 6480464 baicalein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:27425033 Th Mouse baicalin multiple interactions EXP 6480464 baicalin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:38016618 Th Mouse Bardoxolone methyl multiple interactions EXP 6480464 bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of TH protein] CTD PMID:25637688 Th Mouse benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to TH promoter] CTD PMID:19654925 Th Mouse benzo[a]pyrene increases expression ISO TH (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of TH mRNA CTD PMID:35870112 Th Mouse benzo[a]pyrene affects methylation ISO TH (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TH promoter CTD PMID:27901495 Th Mouse benzo[a]pyrene decreases expression ISO Th (Rattus norvegicus) 6480464 Benzo(a)pyrene results in decreased expression of TH protein CTD PMID:28049045 Th Mouse beta-lapachone increases expression ISO TH (Homo sapiens) 6480464 beta-lapachone results in increased expression of TH mRNA CTD PMID:38218311 Th Mouse bicuculline multiple interactions ISO Th (Rattus norvegicus) 6480464 Bicuculline promotes the reaction [Reserpine affects the activity of TH protein] and Bicuculline promotes the reaction [Reserpine results in increased expression of TH mRNA] CTD PMID:1981253 Th Mouse bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of TH mRNA CTD PMID:15674843 Th Mouse bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of TH protein CTD PMID:19481886 Th Mouse bis(2-ethylhexyl) phthalate increases expression ISO Th (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of TH mRNA CTD PMID:29982774 Th Mouse bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TH protein] more ... CTD PMID:19481886 Th Mouse bisphenol A affects expression ISO Th (Rattus norvegicus) 6480464 bisphenol A affects the expression of TH protein CTD PMID:16427766 Th Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TH mRNA CTD PMID:30951980 Th Mouse bisphenol A multiple interactions ISO TH (Homo sapiens) 6480464 IGF1 protein inhibits the reaction [bisphenol A results in decreased expression of TH mRNA] and IGF1 protein inhibits the reaction [bisphenol A results in decreased expression of TH protein] CTD PMID:27271280 Th Mouse bisphenol A decreases expression ISO TH (Homo sapiens) 6480464 bisphenol A results in decreased expression of TH mRNA and bisphenol A results in decreased expression of TH protein CTD PMID:27271280 Th Mouse bisphenol A increases expression ISO Th (Rattus norvegicus) 6480464 bisphenol A results in increased expression of TH mRNA CTD PMID:26141625 Th Mouse bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TH protein CTD PMID:19481886 Th Mouse bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TH protein] more ... CTD PMID:19481886 and PMID:30951980 Th Mouse bisphenol A decreases expression ISO Th (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of TH mRNA and bisphenol A results in decreased expression of TH protein CTD PMID:16909604 more ... Th Mouse bisphenol F decreases expression ISO Th (Rattus norvegicus) 6480464 4 and 4'-bisphenol F results in decreased expression of TH mRNA CTD PMID:26186136 Th Mouse bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of TH mRNA CTD PMID:30951980 Th Mouse BQ 123 multiple interactions ISO Th (Rattus norvegicus) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [EDN1 protein results in increased activity of TH protein] and cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [EDN1 protein results in increased expression of TH mRNA] CTD PMID:11911850 Th Mouse bromochloroacetic acid affects expression EXP 6480464 bromochloroacetic acid affects the expression of TH protein CTD PMID:21296659 Th Mouse bucladesine increases expression ISO Th (Rattus norvegicus) 6480464 Bucladesine results in increased expression of TH mRNA CTD PMID:19912776 Th Mouse butanal increases expression ISO TH (Homo sapiens) 6480464 butyraldehyde results in increased expression of TH mRNA CTD PMID:26079696 Th Mouse Butylparaben multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 Th Mouse cadmium atom increases expression ISO TH (Homo sapiens) 6480464 Cadmium results in increased expression of TH mRNA CTD PMID:21694771 Th Mouse cadmium dichloride decreases methylation ISO Th (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased methylation of TH promoter CTD PMID:22457795 Th Mouse caffeine multiple interactions EXP 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 and PMID:7996441 Th Mouse calcitriol multiple interactions ISO TH (Homo sapiens) 6480464 [Calcitriol co-treated with VDR protein] results in increased expression of TH mRNA and [Calcitriol co-treated with VDR protein] results in increased expression of TH protein CTD PMID:26210580 Th Mouse calcitriol decreases expression ISO Th (Rattus norvegicus) 6480464 Calcitriol results in decreased expression of TH protein CTD PMID:32147540 Th Mouse cannabidiol multiple interactions EXP 6480464 [Cannabidiol co-treated with Naltrexone] results in decreased expression of TH mRNA more ... CTD PMID:29624642 and PMID:29859012 Th Mouse carmustine increases activity ISO Th (Rattus norvegicus) 6480464 Carmustine results in increased activity of TH protein CTD PMID:14670008 Th Mouse carmustine increases expression ISO Th (Rattus norvegicus) 6480464 Carmustine results in increased expression of TH mRNA and Carmustine results in increased expression of TH protein CTD PMID:14670008 Th Mouse carnosic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:25446857 Th Mouse Carnosol multiple interactions EXP 6480464 5-iodo-3-((3 more ... CTD PMID:17047462 Th Mouse Carnosol increases expression EXP 6480464 carnosol results in increased expression of TH protein CTD PMID:17047462 Th Mouse carvedilol multiple interactions ISO Th (Rattus norvegicus) 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of TH protein] CTD PMID:22413959 Th Mouse carvedilol decreases expression ISO Th (Rattus norvegicus) 6480464 carvedilol results in decreased expression of TH mRNA and carvedilol results in decreased expression of TH protein CTD PMID:20359859 Th Mouse chelerythrine multiple interactions ISO Th (Rattus norvegicus) 6480464 chelerythrine inhibits the reaction [3-(2-hydroxy-4-(1 more ... CTD PMID:18992715 Th Mouse chitosan multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein] CTD PMID:22704994 Th Mouse Chloralose multiple interactions ISO Th (Rattus norvegicus) 6480464 [Nitroprusside co-treated with Urethane co-treated with Chloralose] results in increased expression of TH protein CTD PMID:12088752 Th Mouse chlorisondamine multiple interactions ISO Th (Rattus norvegicus) 6480464 Chlorisondamine inhibits the reaction [Reserpine results in increased expression of TH mRNA] and Chlorisondamine promotes the reaction [Reserpine results in increased expression of TH mRNA] CTD PMID:1714554 Th Mouse chlorisondamine increases expression ISO Th (Rattus norvegicus) 6480464 Chlorisondamine results in increased expression of TH mRNA CTD PMID:1714554 Th Mouse chlorpyrifos increases expression ISO Th (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of TH mRNA CTD PMID:18812211 Th Mouse chlorpyrifos increases expression ISO TH (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of TH mRNA and Chlorpyrifos results in increased expression of TH protein CTD PMID:34259569 Th Mouse chlorpyrifos multiple interactions ISO TH (Homo sapiens) 6480464 CDH8 protein affects the reaction [Chlorpyrifos results in increased expression of TH protein] CTD PMID:34259569 Th Mouse chlorpyrifos decreases expression ISO TH (Homo sapiens) 6480464 Chlorpyrifos results in decreased expression of TH protein CTD PMID:24793810 Th Mouse chlorpyrifos decreases expression ISO Th (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of TH protein CTD PMID:22714038 and PMID:29859868 Th Mouse chlorpyrifos multiple interactions ISO Th (Rattus norvegicus) 6480464 acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein] and Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein] CTD PMID:22714038 and PMID:29859868 Th Mouse cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of TH mRNA CTD PMID:15464296 and PMID:15471895 Th Mouse clonidine multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Dopamine more ... CTD PMID:19067675 Th Mouse clonidine (amino form) multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Dopamine more ... CTD PMID:19067675 Th Mouse clonidine (imino form) multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Dopamine more ... CTD PMID:19067675 Th Mouse clozapine decreases activity ISO Th (Rattus norvegicus) 6480464 Clozapine results in decreased activity of TH protein CTD PMID:15983997 Th Mouse clozapine multiple interactions ISO Th (Rattus norvegicus) 6480464 Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein] CTD PMID:15983997 Th Mouse clozapine increases expression ISO Th (Rattus norvegicus) 6480464 Clozapine results in increased expression of TH protein CTD PMID:17028028 Th Mouse clozapine decreases expression ISO Th (Rattus norvegicus) 6480464 Clozapine results in decreased expression of TH mRNA and Clozapine results in decreased expression of TH protein CTD PMID:12645084 and PMID:15983997 Th Mouse clozapine increases activity EXP 6480464 Clozapine results in increased activity of TH protein CTD PMID:16415089 Th Mouse clozapine multiple interactions EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:16402076 and PMID:16415089 Th Mouse cobalt dichloride multiple interactions EXP 6480464 [cobaltous chloride co-treated with Y 27632] results in increased expression of TH protein CTD PMID:16772336 Th Mouse cobalt dichloride increases expression ISO Th (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of TH mRNA CTD PMID:9458725 Th Mouse cocaine affects expression ISO Th (Rattus norvegicus) 6480464 Cocaine affects the expression of TH protein CTD PMID:12787079 Th Mouse cocaine decreases phosphorylation EXP 6480464 Cocaine results in decreased phosphorylation of TH protein CTD PMID:23499958 Th Mouse cocaine multiple interactions EXP 6480464 resveratrol promotes the reaction [Cocaine results in decreased phosphorylation of TH protein] CTD PMID:23499958 Th Mouse cocaine increases expression ISO Th (Rattus norvegicus) 6480464 Cocaine results in increased expression of TH protein CTD PMID:18992788 Th Mouse cocaine multiple interactions ISO Th (Rattus norvegicus) 6480464 Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine] and Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]] CTD PMID:20729865 Th Mouse cocaine decreases expression ISO Th (Rattus norvegicus) 6480464 Cocaine results in decreased expression of TH protein CTD PMID:11391778 Th Mouse colforsin daropate hydrochloride multiple interactions ISO Th (Rattus norvegicus) 6480464 3-(2-hydroxy-4-(1 more ... CTD PMID:18992715 Th Mouse colforsin daropate hydrochloride increases expression ISO TH (Homo sapiens) 6480464 Colforsin results in increased expression of TH protein CTD PMID:34897981 Th Mouse colforsin daropate hydrochloride increases activity ISO Th (Rattus norvegicus) 6480464 Colforsin results in increased activity of TH protein CTD PMID:9288946 Th Mouse colforsin daropate hydrochloride increases expression ISO Th (Rattus norvegicus) 6480464 Colforsin results in increased expression of TH mRNA and Colforsin results in increased expression of TH protein CTD PMID:14550852 and PMID:18992715 Th Mouse copper atom multiple interactions EXP 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased expression of TH protein CTD PMID:36775208 Th Mouse copper(0) multiple interactions EXP 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased expression of TH protein CTD PMID:36775208 Th Mouse copper(II) sulfate multiple interactions EXP 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased expression of TH protein and Copper Sulfate inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased activity of TH protein] CTD PMID:20184101 and PMID:36775208 Th Mouse copper(II) sulfate decreases expression ISO Th (Rattus norvegicus) 6480464 Copper Sulfate results in decreased expression of TH mRNA CTD PMID:18369385 Th Mouse corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of TH protein CTD PMID:28186389 Th Mouse Cuprizon decreases expression ISO Th (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of TH mRNA CTD PMID:27523638 Th Mouse curcumin multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein] and Curcumin inhibits the reaction [sodium arsenite results in decreased expression of TH protein] CTD PMID:19631675 more ... Th Mouse curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:31187328 Th Mouse curcumin multiple interactions ISO TH (Homo sapiens) 6480464 Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:30463061 Th Mouse cyanazine increases expression ISO Th (Rattus norvegicus) 6480464 cyanazine results in increased expression of TH protein CTD PMID:14550852 Th Mouse cyanocob(III)alamin multiple interactions ISO Th (Rattus norvegicus) 6480464 Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein] CTD PMID:38049026 Th Mouse cyclosporin A decreases methylation ISO TH (Homo sapiens) 6480464 Cyclosporine results in decreased methylation of TH promoter CTD PMID:27989131 Th Mouse cyhalothrin decreases expression ISO Th (Rattus norvegicus) 6480464 cyhalothrin results in decreased expression of TH mRNA and cyhalothrin results in decreased expression of TH protein CTD PMID:22366556 more ... Th Mouse cypermethrin decreases expression ISO Th (Rattus norvegicus) 6480464 cypermethrin results in decreased expression of TH mRNA and cypermethrin results in decreased expression of TH protein CTD PMID:26115703 Th Mouse cytarabine decreases expression ISO TH (Homo sapiens) 6480464 Cytarabine results in decreased expression of TH protein CTD PMID:21198554 Th Mouse dabigatran multiple interactions ISO Th (Rattus norvegicus) 6480464 Dabigatran inhibits the reaction [Rotenone results in decreased expression of TH mRNA] CTD PMID:28585189 Th Mouse DDE multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 Th Mouse desferrioxamine B increases expression ISO Th (Rattus norvegicus) 6480464 Deferoxamine results in increased expression of TH mRNA CTD PMID:9458725 Th Mouse desipramine multiple interactions ISO Th (Rattus norvegicus) 6480464 Desipramine inhibits the reaction [Reserpine results in increased expression of TH mRNA] CTD PMID:1717808 Th Mouse dexamethasone increases expression ISO Th (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of TH protein CTD PMID:14550852 Th Mouse dexamethasone decreases expression ISO Th (Rattus norvegicus) 6480464 Dexamethasone results in decreased expression of TH mRNA CTD PMID:11072875 Th Mouse diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of TH mRNA CTD PMID:23392890 and PMID:23518225 Th Mouse diarsenic trioxide multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of TH mRNA] CTD PMID:23392890 Th Mouse diarsenic trioxide decreases expression ISO TH (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of TH protein CTD PMID:11027660 Th Mouse diazinon increases expression ISO Th (Rattus norvegicus) 6480464 Diazinon results in increased expression of TH mRNA CTD PMID:17452286 and PMID:18812211 Th Mouse dichlorvos increases activity ISO Th (Rattus norvegicus) 6480464 Dichlorvos results in increased activity of TH protein CTD PMID:12186780 Th Mouse dichlorvos multiple interactions ISO Th (Rattus norvegicus) 6480464 Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein] CTD PMID:12186780 Th Mouse dieldrin increases expression ISO Th (Rattus norvegicus) 6480464 Dieldrin results in increased expression of TH mRNA CTD PMID:18812211 Th Mouse diethyldithiocarbamic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 Ditiocarb results in decreased expression of and results in increased phosphorylation of TH protein CTD PMID:22874009 Th Mouse dioxygen increases expression ISO Th (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of TH mRNA CTD PMID:10486562 more ... Th Mouse dipyridamole decreases expression ISO Th (Rattus norvegicus) 6480464 Dipyridamole results in decreased expression of TH protein CTD PMID:17568153 Th Mouse dopamine increases chemical synthesis ISO TH (Homo sapiens) 6480464 TH protein results in increased chemical synthesis of Dopamine CTD PMID:19815691 Th Mouse dopamine affects abundance EXP 6480464 TH protein affects the abundance of Dopamine CTD PMID:10984662 and PMID:8707341 Th Mouse dopamine increases chemical synthesis ISO Th (Rattus norvegicus) 6480464 TH protein results in increased chemical synthesis of Dopamine CTD PMID:10661506 Th Mouse dopamine affects abundance ISO Th (Rattus norvegicus) 6480464 TH affects the abundance of Dopamine CTD PMID:20615977 Th Mouse dopamine decreases activity ISO Th (Rattus norvegicus) 6480464 Dopamine results in decreased activity of TH protein CTD PMID:2884129 Th Mouse dopamine multiple interactions ISO Th (Rattus norvegicus) 6480464 1-phenyl-3-dimethylamino-1 more ... CTD PMID:10661506 more ... Th Mouse dopamine affects chemical synthesis EXP 6480464 TH protein affects the chemical synthesis of Dopamine CTD PMID:9822156 Th Mouse dopamine multiple interactions EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:10984662 more ... Th Mouse dopaminechrome (enol form) decreases expression ISO Th (Rattus norvegicus) 6480464 aminochrome 1 results in decreased expression of TH protein CTD PMID:29588162 Th Mouse edaravone multiple interactions ISO Th (Rattus norvegicus) 6480464 Edaravone inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:27108097 Th Mouse elemental selenium increases activity ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased activity of TH protein CTD PMID:11113527 Th Mouse elemental selenium increases expression ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased expression of TH mRNA CTD PMID:11113527 Th Mouse elemental selenium multiple interactions ISO Th (Rattus norvegicus) 6480464 [Selenium deficiency results in increased activity of TH protein] which results in increased chemical synthesis of Dopamine CTD PMID:11113527 Th Mouse enzacamene multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 Th Mouse epibatidine multiple interactions ISO Th (Rattus norvegicus) 6480464 1 more ... CTD PMID:15588622 Th Mouse epibatidine increases expression ISO Th (Rattus norvegicus) 6480464 epibatidine results in increased expression of TH mRNA CTD PMID:15588622 Th Mouse ethanol multiple interactions ISO Th (Rattus norvegicus) 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of TH protein] CTD PMID:22413959 Th Mouse ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of TH protein CTD PMID:26747301 and PMID:34808223 Th Mouse ethanol multiple interactions EXP 6480464 Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein] and Ethanol promotes the reaction [mephedrone results in decreased expression of TH protein] CTD PMID:26747301 and PMID:34590183 Th Mouse ethanol increases expression ISO Th (Rattus norvegicus) 6480464 Ethanol results in increased expression of TH protein CTD PMID:22413959 Th Mouse fasudil multiple interactions ISO Th (Rattus norvegicus) 6480464 [[propionic acid co-treated with fasudil] affects the susceptibility to Rotenone] which results in increased expression of TH mRNA CTD PMID:32481507 Th Mouse fenvalerate multiple interactions ISO Th (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [fenvalerate results in decreased expression of TH protein] and SB 203580 inhibits the reaction [fenvalerate results in decreased expression of TH protein] CTD PMID:31734597 Th Mouse fenvalerate decreases expression ISO Th (Rattus norvegicus) 6480464 fenvalerate results in decreased expression of TH protein CTD PMID:31734597 Th Mouse ferrostatin-1 multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:36435477 Th Mouse fipronil decreases expression ISO TH (Homo sapiens) 6480464 fipronil results in decreased expression of TH protein CTD PMID:21296133 Th Mouse flavonoids increases expression ISO Th (Rattus norvegicus) 6480464 Flavonoids results in increased expression of TH mRNA CTD PMID:18035473 Th Mouse fluoxetine decreases expression EXP 6480464 Fluoxetine results in decreased expression of TH mRNA CTD PMID:20857517 Th Mouse fluoxetine affects expression ISO Th (Rattus norvegicus) 6480464 Fluoxetine affects the expression of TH CTD PMID:26475043 Th Mouse fluoxetine increases expression ISO Th (Rattus norvegicus) 6480464 Fluoxetine results in increased expression of TH mRNA CTD PMID:1351783 and PMID:20626387 Th Mouse fluoxetine decreases expression ISO Th (Rattus norvegicus) 6480464 Fluoxetine results in decreased expression of TH mRNA CTD PMID:15936043 Th Mouse fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of TH mRNA CTD PMID:20374287 Th Mouse formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of TH protein CTD PMID:15064152 Th Mouse fructose increases expression EXP 6480464 Fructose results in increased expression of TH mRNA CTD PMID:16843071 Th Mouse ganglioside GM1 increases activity ISO Th (Rattus norvegicus) 6480464 G(M1) Ganglioside results in increased activity of TH protein CTD PMID:14552908 Th Mouse genistein affects expression ISO Th (Rattus norvegicus) 6480464 Genistein affects the expression of TH protein CTD PMID:16427766 Th Mouse genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein] CTD PMID:20455021 Th Mouse geraniol multiple interactions EXP 6480464 geraniol inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23943375 Th Mouse ginkgetin multiple interactions EXP 6480464 ginkgetin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:25968939 Th Mouse ginsenoside Re multiple interactions EXP 6480464 3-((3 more ... CTD PMID:29467000 Th Mouse ginsenoside Re multiple interactions ISO TH (Homo sapiens) 6480464 ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] CTD PMID:25523949 Th Mouse glyburide multiple interactions EXP 6480464 Glyburide promotes the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:16725203 Th Mouse glycidol decreases expression ISO Th (Rattus norvegicus) 6480464 glycidol results in decreased expression of TH mRNA CTD PMID:33150645 Th Mouse glycidol increases methylation ISO Th (Rattus norvegicus) 6480464 glycidol results in increased methylation of TH promoter CTD PMID:33150595 Th Mouse guanethidine decreases expression ISO Th (Rattus norvegicus) 6480464 Guanethidine results in decreased expression of TH protein CTD PMID:9460767 Th Mouse GW 1929 multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] and GW 1929 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:27435855 Th Mouse haloperidol increases expression ISO Th (Rattus norvegicus) 6480464 Haloperidol results in increased expression of TH protein CTD PMID:17028028 Th Mouse heptachlor increases expression EXP 6480464 Heptachlor results in increased expression of TH protein CTD PMID:16112329 Th Mouse herbicide decreases expression ISO Th (Rattus norvegicus) 6480464 Herbicides results in decreased expression of TH mRNA CTD PMID:23123945 Th Mouse hydrogen peroxide multiple interactions ISO TH (Homo sapiens) 6480464 TH protein inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein] CTD PMID:19815691 Th Mouse hydrogen peroxide affects expression ISO Th (Rattus norvegicus) 6480464 Hydrogen Peroxide affects the expression of TH mRNA CTD PMID:9458725 Th Mouse hydrogen peroxide affects abundance ISO Th (Rattus norvegicus) 6480464 TH protein affects the abundance of Hydrogen Peroxide CTD PMID:9458725 Th Mouse hydrogen peroxide affects response to substance ISO TH (Homo sapiens) 6480464 TH protein affects the susceptibility to Hydrogen Peroxide CTD PMID:19815691 Th Mouse icariin multiple interactions ISO Th (Rattus norvegicus) 6480464 icariin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:31251943 Th Mouse idazoxan increases expression ISO Th (Rattus norvegicus) 6480464 Idazoxan results in increased expression of TH mRNA CTD PMID:1351783 Th Mouse imidacloprid multiple interactions ISO Th (Rattus norvegicus) 6480464 [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]] more ... CTD PMID:29246838 Th Mouse imidacloprid increases expression ISO Th (Rattus norvegicus) 6480464 imidacloprid results in increased expression of TH mRNA and imidacloprid results in increased expression of TH protein CTD PMID:29246838 Th Mouse juglone multiple interactions EXP 6480464 juglone inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23754278 Th Mouse ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [Maneb results in decreased expression of TH protein] more ... CTD PMID:19594327 and PMID:22334051 Th Mouse KT 5720 decreases expression ISO Th (Rattus norvegicus) 6480464 KT 5720 results in decreased expression of TH mRNA CTD PMID:18992715 Th Mouse KT 5720 multiple interactions ISO Th (Rattus norvegicus) 6480464 KT 5720 inhibits the reaction [Colforsin results in increased expression of TH mRNA] and KT 5720 inhibits the reaction [HU 211 results in decreased expression of TH mRNA] CTD PMID:18992715 Th Mouse L-ascorbic acid increases expression ISO Th (Rattus norvegicus) 6480464 Ascorbic Acid results in increased expression of TH mRNA and Ascorbic Acid results in increased expression of TH protein CTD PMID:15372504 and PMID:18772553 Th Mouse L-ascorbic acid decreases expression ISO Th (Rattus norvegicus) 6480464 Ascorbic Acid results in decreased expression of TH protein CTD PMID:25891525 Th Mouse L-ascorbic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein and [Ascorbic Acid co-treated with Vitamin E] results in increased expression of TH protein CTD PMID:18772553 and PMID:25891525 Th Mouse L-ascorbic acid decreases expression EXP 6480464 Ascorbic Acid results in decreased expression of TH protein CTD PMID:22285708 Th Mouse lead(0) decreases expression EXP 6480464 Lead results in decreased expression of TH protein CTD PMID:21703292 Th Mouse linalool decreases expression ISO Th (Rattus norvegicus) 6480464 linalool results in decreased expression of TH mRNA CTD PMID:20536181 Th Mouse linuron multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 Th Mouse lipopolysaccharide decreases methylation EXP 6480464 Lipopolysaccharides results in decreased methylation of TH gene CTD PMID:21212295 Th Mouse lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of TH protein CTD PMID:29338785 Th Mouse lipopolysaccharide multiple interactions ISO Th (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased phosphorylation of and results in increased activity of TH protein CTD PMID:23483921 Th Mouse lipopolysaccharide multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of TH gene and VCE-003 analog inhibits the reaction [Lipopolysaccharides results in decreased expression of TH protein] CTD PMID:21212295 and PMID:29338785 Th Mouse lithium atom multiple interactions ISO Th (Rattus norvegicus) 6480464 Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19149911 Th Mouse lithium hydride multiple interactions ISO Th (Rattus norvegicus) 6480464 Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19149911 Th Mouse lovastatin increases expression ISO TH (Homo sapiens) 6480464 Lovastatin results in increased expression of TH protein CTD PMID:20694854 Th Mouse lovastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse lovastatin increases expression EXP 6480464 Lovastatin results in increased expression of TH protein CTD PMID:20694854 Th Mouse lovastatin multiple interactions ISO TH (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [HU 211 results in decreased expression of TH mRNA] CTD PMID:18950629 Th Mouse maneb decreases expression EXP 6480464 Maneb results in decreased expression of TH protein CTD PMID:22334051 Th Mouse maneb multiple interactions ISO Th (Rattus norvegicus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of TH more ... CTD PMID:24376148 and PMID:29152652 Th Mouse maneb multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein] more ... CTD PMID:11124998 more ... Th Mouse manganese atom decreases expression ISO Th (Rattus norvegicus) 6480464 Manganese results in decreased expression of TH mRNA and Manganese results in decreased expression of TH protein CTD PMID:16943606 more ... Th Mouse manganese atom multiple interactions ISO Th (Rattus norvegicus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein CTD PMID:38129942 Th Mouse manganese atom multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein and Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein] CTD PMID:34590183 Th Mouse manganese(0) decreases expression ISO Th (Rattus norvegicus) 6480464 Manganese results in decreased expression of TH mRNA and Manganese results in decreased expression of TH protein CTD PMID:16943606 more ... Th Mouse manganese(0) multiple interactions ISO Th (Rattus norvegicus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein CTD PMID:38129942 Th Mouse manganese(0) multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein and Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein] CTD PMID:34590183 Th Mouse manganese(II) chloride multiple interactions ISO Th (Rattus norvegicus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein more ... CTD PMID:21310168 more ... Th Mouse manganese(II) chloride decreases expression ISO TH (Homo sapiens) 6480464 manganese chloride results in decreased expression of TH mRNA CTD PMID:27913844 Th Mouse manganese(II) chloride increases methylation ISO TH (Homo sapiens) 6480464 manganese chloride results in increased methylation of TH gene CTD PMID:27913844 Th Mouse manganese(II) chloride decreases expression ISO Th (Rattus norvegicus) 6480464 manganese chloride results in decreased expression of TH protein CTD PMID:20798247 more ... Th Mouse manganese(II) chloride multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein more ... CTD PMID:24969583 more ... Th Mouse manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of TH mRNA and manganese chloride results in decreased expression of TH protein CTD PMID:24969583 more ... Th Mouse manganese(II) chloride increases expression ISO Th (Rattus norvegicus) 6480464 manganese chloride results in increased expression of TH mRNA and manganese chloride results in increased expression of TH protein CTD PMID:12106697 Th Mouse manganese(II) chloride decreases activity ISO Th (Rattus norvegicus) 6480464 manganese chloride results in decreased activity of TH protein CTD PMID:21310168 Th Mouse manganese(II) sulfate decreases expression ISO Th (Rattus norvegicus) 6480464 manganese sulfate results in decreased expression of TH mRNA CTD PMID:16943606 Th Mouse melatonin multiple interactions ISO Th (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Methamphetamine results in decreased expression of TH protein] and Melatonin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:18289173 and PMID:19409439 Th Mouse melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:20964710 more ... Th Mouse mephedrone multiple interactions EXP 6480464 Ethanol promotes the reaction [mephedrone results in decreased expression of TH protein] CTD PMID:26747301 Th Mouse mephedrone decreases expression ISO Th (Rattus norvegicus) 6480464 mephedrone results in decreased expression of TH protein CTD PMID:25817894 Th Mouse mephedrone decreases expression EXP 6480464 mephedrone results in decreased expression of TH protein CTD PMID:26747301 Th Mouse mercaptopurine multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] and Mercaptopurine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:27435855 Th Mouse metformin multiple interactions ISO Th (Rattus norvegicus) 6480464 Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein] CTD PMID:35085591 Th Mouse methamphetamine decreases expression ISO TH (Homo sapiens) 6480464 Methamphetamine results in decreased expression of TH protein CTD PMID:16622715 Th Mouse methamphetamine multiple interactions ISO TH (Homo sapiens) 6480464 ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] more ... CTD PMID:25523949 Th Mouse methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of TH mRNA and Methamphetamine results in decreased expression of TH protein CTD PMID:12871582 more ... Th Mouse methamphetamine decreases activity EXP 6480464 Methamphetamine results in decreased activity of TH protein CTD PMID:1381816 more ... Th Mouse methamphetamine affects expression ISO Th (Rattus norvegicus) 6480464 Methamphetamine affects the expression of TH mRNA CTD PMID:24042092 Th Mouse methamphetamine decreases expression ISO Th (Rattus norvegicus) 6480464 Methamphetamine results in decreased expression of TH protein CTD PMID:10773198 more ... Th Mouse methamphetamine decreases activity ISO Th (Rattus norvegicus) 6480464 Methamphetamine results in decreased activity of TH protein CTD PMID:2579200 Th Mouse methamphetamine multiple interactions ISO Th (Rattus norvegicus) 6480464 diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein] more ... CTD PMID:15276877 more ... Th Mouse methamphetamine affects response to substance EXP 6480464 TH protein affects the susceptibility to Methamphetamine CTD PMID:9822156 Th Mouse methamphetamine multiple interactions EXP 6480464 3-((3 more ... CTD PMID:10984662 more ... Th Mouse methoxychlor increases methylation ISO Th (Rattus norvegicus) 6480464 Methoxychlor results in increased methylation of TH gene CTD PMID:23303685 Th Mouse methyllycaconitine multiple interactions ISO TH (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased expression of TH mRNA] CTD PMID:17498763 Th Mouse methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of TH mRNA CTD PMID:21385734 Th Mouse methylmercury chloride multiple interactions EXP 6480464 3 and 9-bis((ethylthio)methyl)-K-252a inhibits the reaction [methylmercuric chloride results in decreased expression of TH mRNA] CTD PMID:21385734 Th Mouse methylphenidate decreases expression EXP 6480464 Methylphenidate results in decreased expression of TH mRNA CTD PMID:22470460 Th Mouse mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse mevalonic acid multiple interactions ISO TH (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse mifepristone decreases expression ISO TH (Homo sapiens) 6480464 Mifepristone results in decreased expression of TH mRNA CTD PMID:17584828 Th Mouse mifepristone multiple interactions ISO Th (Rattus norvegicus) 6480464 Mifepristone inhibits the reaction [Monocrotophos results in increased activity of TH protein] CTD PMID:22305719 Th Mouse minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:38189626 Th Mouse misonidazole increases activity EXP 6480464 Misonidazole results in increased activity of TH protein CTD PMID:2875048 Th Mouse misonidazole increases expression EXP 6480464 Misonidazole results in increased expression of TH protein CTD PMID:2875048 Th Mouse mono(2-ethylhexyl) phthalate decreases expression ISO Th (Rattus norvegicus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of TH mRNA CTD PMID:21145954 Th Mouse mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TH mRNA CTD PMID:36189433 Th Mouse mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of TH mRNA CTD PMID:22401849 Th Mouse monocrotophos multiple interactions ISO Th (Rattus norvegicus) 6480464 Mifepristone inhibits the reaction [Monocrotophos results in increased activity of TH protein] CTD PMID:22305719 Th Mouse monocrotophos increases activity ISO Th (Rattus norvegicus) 6480464 Monocrotophos results in increased activity of TH protein CTD PMID:22305719 Th Mouse monosodium L-glutamate decreases expression ISO Th (Rattus norvegicus) 6480464 Sodium Glutamate results in decreased expression of TH mRNA CTD PMID:1980722 Th Mouse monosodium L-glutamate decreases activity ISO Th (Rattus norvegicus) 6480464 Sodium Glutamate results in decreased activity of TH protein CTD PMID:1980722 Th Mouse montelukast multiple interactions ISO Th (Rattus norvegicus) 6480464 montelukast inhibits the reaction [Rotenone results in increased expression of TH protein] CTD PMID:30222980 Th Mouse morphine multiple interactions ISO Th (Rattus norvegicus) 6480464 [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of TH protein] more ... CTD PMID:15541421 more ... Th Mouse morphine decreases expression ISO Th (Rattus norvegicus) 6480464 Morphine results in decreased expression of TH protein CTD PMID:26386147 Th Mouse morphine multiple interactions EXP 6480464 [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein and CRHR1 gene mutant form inhibits the reaction [[Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein] CTD PMID:25582704 Th Mouse morphine increases phosphorylation ISO Th (Rattus norvegicus) 6480464 Morphine deficiency results in increased phosphorylation of TH protein CTD PMID:24398105 Th Mouse morphine increases expression ISO Th (Rattus norvegicus) 6480464 Morphine results in increased expression of TH protein CTD PMID:15541421 Th Mouse N(gamma)-nitro-L-arginine methyl ester decreases expression EXP 6480464 NG-Nitroarginine Methyl Ester results in decreased expression of TH protein CTD PMID:31187328 Th Mouse N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Th (Rattus norvegicus) 6480464 [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3 more ... CTD PMID:18992715 and PMID:29246838 Th Mouse N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases expression ISO Th (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of TH mRNA CTD PMID:18992715 Th Mouse N-acetyl-L-cysteine multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein and Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein] CTD PMID:22714038 and PMID:25891525 Th Mouse N-acetyl-L-cysteine decreases expression ISO Th (Rattus norvegicus) 6480464 Acetylcysteine results in decreased expression of TH protein CTD PMID:25891525 Th Mouse N-ethyl-N-nitrosourea increases mutagenesis ISO Th (Rattus norvegicus) 6480464 Ethylnitrosourea results in increased mutagenesis of TH gene CTD PMID:16495775 Th Mouse N-ethylmaleimide multiple interactions ISO Th (Rattus norvegicus) 6480464 Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein] CTD PMID:15983997 Th Mouse N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]] more ... CTD PMID:20184101 more ... Th Mouse N-methyl-4-phenylpyridinium increases expression ISO TH (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of TH mRNA CTD PMID:24810058 Th Mouse N-methyl-4-phenylpyridinium decreases expression ISO TH (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of TH protein CTD PMID:26364587 and PMID:30463061 Th Mouse N-methyl-4-phenylpyridinium multiple interactions ISO TH (Homo sapiens) 6480464 BMP2 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] more ... CTD PMID:20007850 more ... Th Mouse N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of TH protein CTD PMID:20007850 more ... Th Mouse N-methyl-4-phenylpyridinium decreases expression ISO Th (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of TH protein CTD PMID:19794909 more ... Th Mouse N-methyl-4-phenylpyridinium multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] more ... CTD PMID:19794909 more ... Th Mouse N-methyl-4-phenylpyridinium decreases activity EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased activity of TH protein CTD PMID:20184101 Th Mouse N-nitrosodiethylamine multiple interactions ISO Th (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TH mRNA CTD PMID:20360939 Th Mouse N-nitrosodiethylamine multiple interactions EXP 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TH gene CTD PMID:23968726 Th Mouse naloxone multiple interactions ISO Th (Rattus norvegicus) 6480464 [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone results in increased phosphorylation of TH protein] and [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein CTD PMID:24398105 and PMID:25308750 Th Mouse naloxone multiple interactions EXP 6480464 [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein and CRHR1 gene mutant form inhibits the reaction [[Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein] CTD PMID:25582704 Th Mouse naloxone increases phosphorylation ISO Th (Rattus norvegicus) 6480464 Naloxone results in increased phosphorylation of TH protein CTD PMID:24398105 Th Mouse naltrexone multiple interactions EXP 6480464 [Cannabidiol co-treated with Naltrexone] results in decreased expression of TH mRNA CTD PMID:29859012 Th Mouse nickel atom increases expression ISO Th (Rattus norvegicus) 6480464 Nickel results in increased expression of TH mRNA CTD PMID:18812211 Th Mouse nickel dichloride multiple interactions ISO TH (Homo sapiens) 6480464 nickel chloride inhibits the reaction [Tretinoin results in increased expression of TH protein] CTD PMID:25614230 Th Mouse nicotine multiple interactions ISO Th (Rattus norvegicus) 6480464 [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]] more ... CTD PMID:29246838 Th Mouse nicotine increases expression ISO Th (Rattus norvegicus) 6480464 Nicotine results in increased expression of TH mRNA and Nicotine results in increased expression of TH protein CTD PMID:29246838 Th Mouse nicotine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:19594327 more ... Th Mouse nicotine multiple interactions ISO TH (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased expression of TH mRNA] CTD PMID:17498763 Th Mouse nicotine increases expression ISO TH (Homo sapiens) 6480464 Nicotine results in increased expression of TH mRNA and Nicotine results in increased expression of TH protein CTD PMID:17498763 Th Mouse nimodipine multiple interactions ISO Th (Rattus norvegicus) 6480464 Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein] CTD PMID:12186780 Th Mouse nitroprusside multiple interactions ISO Th (Rattus norvegicus) 6480464 [Nitroprusside co-treated with Urethane co-treated with Chloralose] results in increased expression of TH protein more ... CTD PMID:12088752 and PMID:16023617 Th Mouse nitroprusside increases expression ISO Th (Rattus norvegicus) 6480464 Nitroprusside results in increased expression of TH protein CTD PMID:12088752 Th Mouse Nookatone multiple interactions ISO Th (Rattus norvegicus) 6480464 nootkatone inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:35833337 Th Mouse Norbinaltorphimine multiple interactions EXP 6480464 3-((3 more ... CTD PMID:29467000 Th Mouse olanzapine multiple interactions ISO Th (Rattus norvegicus) 6480464 olanzapine inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:15276877 Th Mouse oleuropein multiple interactions EXP 6480464 oleuropein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:36774383 Th Mouse oridonin multiple interactions ISO Th (Rattus norvegicus) 6480464 oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA] CTD PMID:31430510 Th Mouse oxidopamine decreases expression ISO Th (Rattus norvegicus) 6480464 Oxidopamine results in decreased expression of TH mRNA and Oxidopamine results in decreased expression of TH protein CTD PMID:11730701 more ... Th Mouse oxidopamine affects response to substance ISO TH (Homo sapiens) 6480464 TH protein affects the susceptibility to Oxidopamine CTD PMID:19815691 Th Mouse oxidopamine multiple interactions ISO TH (Homo sapiens) 6480464 TH protein inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein] CTD PMID:19815691 Th Mouse oxidopamine multiple interactions EXP 6480464 LY 344864 inhibits the reaction [Oxidopamine results in decreased expression of TH protein] more ... CTD PMID:16914382 more ... Th Mouse oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of TH mRNA and Oxidopamine results in decreased expression of TH protein CTD PMID:15899244 more ... Th Mouse oxidopamine multiple interactions ISO Th (Rattus norvegicus) 6480464 2-chloro-5-hydroxyphenylglycine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the expression of TH protein] more ... CTD PMID:12585172 more ... Th Mouse P(1),P(4)-bis(5'-adenosyl) tetraphosphate multiple interactions ISO Th (Rattus norvegicus) 6480464 diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19442829 Th Mouse paracetamol multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides and Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 Th Mouse paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of TH protein CTD PMID:22334051 more ... Th Mouse paraquat multiple interactions ISO TH (Homo sapiens) 6480464 MT2A protein inhibits the reaction [Paraquat results in increased expression of TH mRNA] CTD PMID:34623211 Th Mouse paraquat affects expression EXP 6480464 Paraquat affects the expression of TH protein CTD PMID:28428137 Th Mouse paraquat decreases expression ISO Th (Rattus norvegicus) 6480464 Paraquat results in decreased expression of TH mRNA and Paraquat results in decreased expression of TH protein CTD PMID:16190885 more ... Th Mouse paraquat increases expression ISO TH (Homo sapiens) 6480464 Paraquat results in increased expression of TH protein CTD PMID:26498265 Th Mouse paraquat increases activity ISO Th (Rattus norvegicus) 6480464 Paraquat results in increased activity of TH protein CTD PMID:24743698 Th Mouse paraquat multiple interactions ISO Th (Rattus norvegicus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of TH more ... CTD PMID:20553223 more ... Th Mouse paraquat multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein] more ... CTD PMID:11124998 more ... Th Mouse pentanal decreases expression ISO TH (Homo sapiens) 6480464 pentanal results in decreased expression of TH mRNA CTD PMID:26079696 Th Mouse perfluorodecanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 Th Mouse perfluorododecanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 Th Mouse perfluorononanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 Th Mouse perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of TH mRNA CTD PMID:26686188 Th Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 Th Mouse perfluorooctanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 Th Mouse perfluoroundecanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 Th Mouse permethrin multiple interactions ISO Th (Rattus norvegicus) 6480464 Permethrin results in decreased expression of and results in decreased activity of TH protein CTD PMID:15461254 Th Mouse permethrin increases expression ISO Th (Rattus norvegicus) 6480464 Permethrin results in increased expression of TH mRNA CTD PMID:31175960 Th Mouse permethrin decreases expression ISO Th (Rattus norvegicus) 6480464 Permethrin results in decreased expression of TH mRNA CTD PMID:15461254 Th Mouse phencyclidine multiple interactions EXP 6480464 Phencyclidine inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:1381816 Th Mouse phencyclidine increases expression EXP 6480464 Phencyclidine results in increased expression of TH mRNA CTD PMID:12105081 Th Mouse Phenelzine increases expression ISO Th (Rattus norvegicus) 6480464 Phenelzine results in increased expression of TH mRNA CTD PMID:1351783 Th Mouse phenethyl caffeate multiple interactions ISO Th (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TH mRNA CTD PMID:20360939 Th Mouse phorbol 13-acetate 12-myristate multiple interactions ISO TH (Homo sapiens) 6480464 [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TH protein CTD PMID:24101030 Th Mouse phorbol 13-acetate 12-myristate increases expression ISO Th (Rattus norvegicus) 6480464 Tetradecanoylphorbol Acetate results in increased expression of TH mRNA CTD PMID:18992715 Th Mouse piperazine decreases expression ISO TH (Homo sapiens) 6480464 Piperazine analog results in decreased expression of TH protein CTD PMID:28874085 Th Mouse piperonyl butoxide multiple interactions EXP 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TH gene CTD PMID:23968726 Th Mouse pirinixic acid multiple interactions ISO TH (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TH mRNA CTD PMID:19710929 Th Mouse pregabalin affects expression EXP 6480464 Pregabalin affects the expression of TH mRNA CTD PMID:22017514 Th Mouse pregabalin increases expression EXP 6480464 Pregabalin results in increased expression of TH mRNA CTD PMID:22489711 Th Mouse probenecid multiple interactions EXP 6480464 1 more ... CTD PMID:19653878 and PMID:25406165 Th Mouse progesterone decreases phosphorylation ISO Th (Rattus norvegicus) 6480464 Progesterone results in decreased phosphorylation of TH protein CTD PMID:18096660 Th Mouse progesterone decreases activity ISO Th (Rattus norvegicus) 6480464 Progesterone results in decreased activity of TH protein CTD PMID:18096660 Th Mouse propanal decreases expression ISO TH (Homo sapiens) 6480464 propionaldehyde results in decreased expression of TH mRNA CTD PMID:26079696 Th Mouse propionic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 [[propionic acid co-treated with fasudil] affects the susceptibility to Rotenone] which results in increased expression of TH mRNA CTD PMID:32481507 Th Mouse propionic acid increases expression ISO Th (Rattus norvegicus) 6480464 propionic acid results in increased expression of TH mRNA CTD PMID:32481507 Th Mouse propofol decreases expression EXP 6480464 Propofol results in decreased expression of TH protein CTD PMID:32612007 Th Mouse prothioconazole increases expression ISO TH (Homo sapiens) 6480464 prothioconazole results in increased expression of TH mRNA CTD PMID:35048155 Th Mouse purine-6-thiol multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] and Mercaptopurine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:27435855 Th Mouse pyrrolidine dithiocarbamate multiple interactions EXP 6480464 pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] and pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] CTD PMID:34082047 Th Mouse pyrroloquinoline quinone multiple interactions ISO Th (Rattus norvegicus) 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:26276080 and PMID:27108097 Th Mouse pyrroloquinoline quinone multiple interactions EXP 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:32860006 Th Mouse quercetin multiple interactions ISO Th (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Rotenone results in decreased activity of TH protein] and Quercetin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:23357119 and PMID:35337893 Th Mouse quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO Th (Rattus norvegicus) 6480464 isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 Th Mouse quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO Th (Rattus norvegicus) 6480464 isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 Th Mouse reserpine increases expression EXP 6480464 Reserpine results in increased expression of TH mRNA CTD PMID:8666980 Th Mouse reserpine increases activity ISO Th (Rattus norvegicus) 6480464 Reserpine results in increased activity of TH protein CTD PMID:1978789 more ... Th Mouse reserpine increases expression ISO Th (Rattus norvegicus) 6480464 Reserpine results in increased expression of TH mRNA and Reserpine results in increased expression of TH protein CTD PMID:11438978 more ... Th Mouse reserpine decreases expression ISO Th (Rattus norvegicus) 6480464 Reserpine results in decreased expression of TH mRNA CTD PMID:20504635 Th Mouse reserpine affects activity ISO Th (Rattus norvegicus) 6480464 Reserpine affects the activity of TH protein CTD PMID:1981253 Th Mouse reserpine increases stability ISO Th (Rattus norvegicus) 6480464 Reserpine results in increased stability of TH mRNA CTD PMID:11161478 Th Mouse reserpine multiple interactions ISO Th (Rattus norvegicus) 6480464 Bicuculline promotes the reaction [Reserpine affects the activity of TH protein] more ... CTD PMID:11438978 more ... Th Mouse resveratrol multiple interactions EXP 6480464 resveratrol promotes the reaction [Cocaine results in decreased phosphorylation of TH protein] CTD PMID:23499958 Th Mouse resveratrol multiple interactions ISO Th (Rattus norvegicus) 6480464 Resveratrol inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:34302886 Th Mouse resveratrol multiple interactions ISO TH (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of TH mRNA CTD PMID:23557933 Th Mouse rimonabant increases activity ISO Th (Rattus norvegicus) 6480464 Rimonabant results in increased activity of TH protein CTD PMID:15882845 Th Mouse rimonabant multiple interactions ISO Th (Rattus norvegicus) 6480464 Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein] and Rimonabant inhibits the reaction [Dronabinol results in increased activity of TH protein] CTD PMID:10700552 more ... Th Mouse risperidone increases expression ISO Th (Rattus norvegicus) 6480464 Risperidone results in increased expression of TH protein CTD PMID:17028028 Th Mouse rotenone multiple interactions EXP 6480464 baicalein inhibits the reaction [Rotenone results in decreased expression of TH protein] more ... CTD PMID:17047462 more ... Th Mouse rotenone decreases activity ISO Th (Rattus norvegicus) 6480464 Rotenone results in decreased activity of TH protein CTD PMID:35187747 and PMID:35337893 Th Mouse rotenone increases expression ISO Th (Rattus norvegicus) 6480464 Rotenone results in increased expression of TH protein CTD PMID:30222980 Th Mouse rotenone decreases expression ISO Th (Rattus norvegicus) 6480464 Rotenone results in decreased expression of TH mRNA and Rotenone results in decreased expression of TH protein CTD PMID:12385818 more ... Th Mouse rotenone multiple interactions ISO Th (Rattus norvegicus) 6480464 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Docosahexaenoic Acids inhibits the reaction [Rotenone results in decreased expression of TH protein]] more ... CTD PMID:15790535 more ... Th Mouse rotenone increases response to substance ISO Th (Rattus norvegicus) 6480464 TH protein results in increased susceptibility to Rotenone CTD PMID:14622122 Th Mouse rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of TH protein CTD PMID:17047462 more ... Th Mouse rottlerin multiple interactions ISO Th (Rattus norvegicus) 6480464 rottlerin inhibits the reaction [manganese chloride results in decreased activity of TH protein] CTD PMID:21310168 Th Mouse rottlerin multiple interactions EXP 6480464 [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased activity of TH protein] and [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:22512859 Th Mouse rutin multiple interactions ISO Th (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 Th Mouse salubrinal multiple interactions ISO Th (Rattus norvegicus) 6480464 salubrinal inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:26446018 Th Mouse saxagliptin multiple interactions ISO Th (Rattus norvegicus) 6480464 saxagliptin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:25446674 Th Mouse SB 203580 multiple interactions ISO Th (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [fenvalerate results in decreased expression of TH protein] and SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of TH protein] CTD PMID:31734597 and PMID:9288946 Th Mouse SCH 23390 multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein] and SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:16088948 and PMID:30922767 Th Mouse selenium atom increases activity ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased activity of TH protein CTD PMID:11113527 Th Mouse selenium atom increases expression ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased expression of TH mRNA CTD PMID:11113527 Th Mouse selenium atom multiple interactions ISO Th (Rattus norvegicus) 6480464 [Selenium deficiency results in increased activity of TH protein] which results in increased chemical synthesis of Dopamine CTD PMID:11113527 Th Mouse simazine decreases expression ISO Th (Rattus norvegicus) 6480464 Simazine results in decreased expression of TH protein CTD PMID:14550852 Th Mouse simazine decreases expression EXP 6480464 Simazine results in decreased expression of TH mRNA and Simazine results in decreased expression of TH protein CTD PMID:34936186 Th Mouse simazine affects expression EXP 6480464 Simazine affects the expression of TH mRNA and Simazine affects the expression of TH protein CTD PMID:29137186 Th Mouse simazine increases expression EXP 6480464 Simazine results in increased expression of TH mRNA and Simazine results in increased expression of TH protein CTD PMID:27513680 and PMID:32822773 Th Mouse simazine multiple interactions EXP 6480464 LMX1A protein promotes the reaction [Simazine results in increased expression of TH protein] CTD PMID:32822773 Th Mouse sodium arsenite multiple interactions EXP 6480464 [sodium arsenite affects the localization of NR4A2 protein] inhibits the reaction [NR4A2 protein results in increased expression of TH mRNA] CTD PMID:23283970 Th Mouse sodium arsenite increases expression ISO Th (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of TH protein CTD PMID:25179238 Th Mouse sodium arsenite decreases expression ISO Th (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of TH protein CTD PMID:19631675 more ... Th Mouse sodium arsenite multiple interactions ISO Th (Rattus norvegicus) 6480464 Curcumin inhibits the reaction [sodium arsenite results in decreased expression of TH protein] more ... CTD PMID:19631675 more ... Th Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of TH protein CTD PMID:27413109 Th Mouse sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of TH mRNA CTD PMID:19121333 more ... Th Mouse sodium chloride increases expression ISO Th (Rattus norvegicus) 6480464 Sodium Chloride results in increased expression of TH mRNA CTD PMID:10613505 Th Mouse Sophoricoside multiple interactions EXP 6480464 sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:37741537 Th Mouse spiperone multiple interactions ISO Th (Rattus norvegicus) 6480464 Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]] CTD PMID:20729865 Th Mouse streptozocin multiple interactions ISO Th (Rattus norvegicus) 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein more ... CTD PMID:35085591 and PMID:38049026 Th Mouse streptozocin decreases expression ISO Th (Rattus norvegicus) 6480464 Streptozocin results in decreased expression of TH protein CTD PMID:38049026 Th Mouse sulforaphane multiple interactions EXP 6480464 sulforaphane inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:23518299 Th Mouse sulpiride multiple interactions ISO Th (Rattus norvegicus) 6480464 Sulpiride inhibits the reaction [Dopamine results in decreased activity of TH protein] and Sulpiride inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:18289173 and PMID:2884129 Th Mouse sulpiride multiple interactions EXP 6480464 Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein] CTD PMID:30922767 Th Mouse sulpiride increases activity ISO Th (Rattus norvegicus) 6480464 Sulpiride results in increased activity of TH protein CTD PMID:2884129 Th Mouse Talipexole dihydrochloride multiple interactions EXP 6480464 talipexole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:9655613 Th Mouse tamoxifen multiple interactions EXP 6480464 Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of TH mRNA] and Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of TH protein] CTD PMID:29183790 Th Mouse tamoxifen decreases expression ISO Th (Rattus norvegicus) 6480464 Tamoxifen results in decreased expression of TH mRNA and Tamoxifen results in decreased expression of TH protein CTD PMID:28463726 Th Mouse tamoxifen multiple interactions ISO Th (Rattus norvegicus) 6480464 Tamoxifen inhibits the reaction [amitraz results in increased expression of TH mRNA] and Tamoxifen inhibits the reaction [amitraz results in increased expression of TH protein] CTD PMID:28463726 Th Mouse taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [arsenic trioxide results in decreased expression of TH mRNA] CTD PMID:23392890 Th Mouse telmisartan multiple interactions EXP 6480464 telmisartan inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:23747572 Th Mouse testosterone decreases expression ISO Th (Rattus norvegicus) 6480464 Testosterone results in decreased expression of TH protein CTD PMID:11883789 Th Mouse topiramate increases expression EXP 6480464 topiramate results in increased expression of TH mRNA CTD PMID:22489711 Th Mouse topiramate affects expression EXP 6480464 topiramate affects the expression of TH mRNA CTD PMID:22017514 Th Mouse trichloroethene decreases expression ISO Th (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of TH protein CTD PMID:33636387 Th Mouse trichloroethene increases expression ISO Th (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of TH mRNA CTD PMID:33387578 Th Mouse triprolidine multiple interactions ISO Th (Rattus norvegicus) 6480464 Triprolidine inhibits the reaction [1-phenyl-3-dimethylamino-1 more ... CTD PMID:10661506 Th Mouse tris(2-butoxyethyl) phosphate affects expression ISO TH (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate affects the expression of TH mRNA CTD PMID:29024780 Th Mouse urethane multiple interactions ISO Th (Rattus norvegicus) 6480464 [Nitroprusside co-treated with Urethane co-treated with Chloralose] results in increased expression of TH protein CTD PMID:12088752 Th Mouse valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of TH mRNA CTD PMID:17963808 Th Mouse valproic acid increases methylation ISO Th (Rattus norvegicus) 6480464 Valproic Acid results in increased methylation of TH promoter CTD PMID:33150595 Th Mouse valproic acid multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of TH mRNA] and Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of TH protein] CTD PMID:29778792 Th Mouse valproic acid affects expression ISO TH (Homo sapiens) 6480464 Valproic Acid affects the expression of TH mRNA CTD PMID:25979313 Th Mouse valproic acid increases expression ISO Th (Rattus norvegicus) 6480464 Valproic Acid results in increased expression of TH mRNA and Valproic Acid results in increased expression of TH protein CTD PMID:18976638 Th Mouse valproic acid decreases expression ISO Th (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of TH mRNA and Valproic Acid results in decreased expression of TH protein CTD PMID:18976638 and PMID:33150595 Th Mouse valproic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 CREB1 protein affects the reaction [Valproic Acid results in increased expression of TH mRNA] and Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:18976638 and PMID:19149911 Th Mouse valproic acid affects expression ISO Th (Rattus norvegicus) 6480464 Valproic Acid affects the expression of TH protein CTD PMID:19460635 Th Mouse vitamin D decreases expression ISO Th (Rattus norvegicus) 6480464 Vitamin D deficiency results in decreased expression of TH mRNA and Vitamin D deficiency results in decreased expression of TH protein CTD PMID:28365874 Th Mouse vitamin E multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with Vitamin E] results in increased expression of TH protein CTD PMID:18772553 Th Mouse vorinostat decreases expression ISO TH (Homo sapiens) 6480464 vorinostat results in decreased expression of TH mRNA CTD PMID:27188386 Th Mouse WIN 55212-2 affects expression ISO Th (Rattus norvegicus) 6480464 (3R)-((2 more ... CTD PMID:29113897 Th Mouse WIN 55212-2 multiple interactions ISO Th (Rattus norvegicus) 6480464 AM 251 affects the reaction [(3R)-((2 more ... CTD PMID:29113897 Th Mouse WIN 55212-2 multiple interactions EXP 6480464 (3R)-((2 more ... CTD PMID:28092019 Th Mouse wortmannin multiple interactions EXP 6480464 wortmannin affects the reaction [HU 211 results in decreased expression of TH mRNA] CTD PMID:18950629 Th Mouse wortmannin multiple interactions ISO Th (Rattus norvegicus) 6480464 [wortmannin co-treated with manganese chloride] results in decreased expression of TH protein CTD PMID:23604964 Th Mouse Y-27632 multiple interactions EXP 6480464 [cobaltous chloride co-treated with Y 27632] results in increased expression of TH protein CTD PMID:16772336 Th Mouse zearalenone decreases expression ISO TH (Homo sapiens) 6480464 Zearalenone results in decreased expression of TH mRNA CTD PMID:24412706 Th Mouse zinc atom increases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in increased expression of TH protein CTD PMID:11165868 Th Mouse zinc atom multiple interactions ISO Th (Rattus norvegicus) 6480464 Paraquat promotes the reaction [Zinc results in decreased expression of TH protein] and Zinc promotes the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:32060784 Th Mouse zinc atom decreases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in decreased expression of TH protein CTD PMID:32060784 Th Mouse zinc sulfate multiple interactions ISO Th (Rattus norvegicus) 6480464 Paraquat promotes the reaction [Zinc Sulfate results in decreased expression of TH protein] and Zinc Sulfate promotes the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:20553223 Th Mouse zinc sulfate decreases expression ISO Th (Rattus norvegicus) 6480464 Zinc Sulfate results in decreased expression of TH protein CTD PMID:20553223 Th Mouse zinc(0) increases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in increased expression of TH protein CTD PMID:11165868 Th Mouse zinc(0) decreases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in decreased expression of TH protein CTD PMID:32060784 Th Mouse zinc(0) multiple interactions ISO Th (Rattus norvegicus) 6480464 Paraquat promotes the reaction [Zinc results in decreased expression of TH protein] and Zinc promotes the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:32060784 Th Mouse zonisamide increases expression ISO TH (Homo sapiens) 6480464 zonisamide results in increased expression of TH mRNA and zonisamide results in increased expression of TH protein CTD PMID:20196486 Th Mouse zonisamide multiple interactions EXP 6480464 [zonisamide co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:19199078 and PMID:19948168 Th Mouse zonisamide increases expression EXP 6480464 zonisamide results in increased expression of TH protein CTD PMID:19199078
