Th Mouse (+)-catechin multiple interactions ISO Th (Rattus norvegicus) 6480464 Catechin inhibits the reaction [Rotenone results in decreased activity of TH protein] CTD PMID:35337893 Th Mouse (+)-sesamin multiple interactions ISO Th (Rattus norvegicus) 6480464 sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:19794909 Th Mouse (+)-taxifolin multiple interactions ISO Th (Rattus norvegicus) 6480464 taxifolin inhibits the reaction [Rotenone results in decreased activity of TH protein] CTD PMID:35187747 Th Mouse (-)-epigallocatechin 3-gallate decreases expression ISO Th (Rattus norvegicus) 6480464 epigallocatechin gallate results in decreased expression of TH protein CTD PMID:27659729 Th Mouse (-)-selegiline multiple interactions ISO Th (Rattus norvegicus) 6480464 Selegiline inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:16490285 Th Mouse (-)-selegiline decreases expression ISO Th (Rattus norvegicus) 6480464 Selegiline results in decreased expression of TH mRNA CTD PMID:11862330 Th Mouse (R)-adrenaline increases chemical synthesis EXP 6480464 TH protein results in increased chemical synthesis of Epinephrine CTD PMID:9822156 Th Mouse (R)-adrenaline multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in increased expression of TH protein] which results in increased abundance of Epinephrine CTD PMID:19067675 Th Mouse (R)-noradrenaline multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which more ... CTD PMID:19067675 Th Mouse (R)-noradrenaline increases chemical synthesis EXP 6480464 TH protein results in increased chemical synthesis of Norepinephrine CTD PMID:9822156 Th Mouse (R,R,R)-alpha-tocopherol multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; more ... CTD PMID:15790535|PMID:25891525 Th Mouse (S)-AMPA decreases expression ISO Th (Rattus norvegicus) 6480464 alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein CTD PMID:36775207 Th Mouse (S)-AMPA multiple interactions ISO Th (Rattus norvegicus) 6480464 1-naphthylacetylspermine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein]; aminophenyl fluorescein more ... CTD PMID:36775207 Th Mouse (S)-amphetamine increases expression EXP 6480464 Dextroamphetamine results in increased expression of TH mRNA CTD PMID:18681898 Th Mouse (S)-naringenin multiple interactions ISO Th (Rattus norvegicus) 6480464 naringenin inhibits the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:34655599 Th Mouse (S)-naringenin decreases expression ISO Th (Rattus norvegicus) 6480464 naringenin results in decreased expression of TH protein CTD PMID:34655599 Th Mouse (S)-nicotine multiple interactions ISO Th (Rattus norvegicus) 6480464 [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the more ... CTD PMID:29246838 Th Mouse (S)-nicotine increases expression ISO Th (Rattus norvegicus) 6480464 Nicotine results in increased expression of TH mRNA; Nicotine results in increased expression of TH more ... CTD PMID:29246838 Th Mouse (S)-nicotine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of TH mRNA; [Nicotine co-treated with polylactic more ... CTD PMID:19594327|PMID:20230807|PMID:23933227|PMID:28082123 Th Mouse (S)-nicotine multiple interactions ISO TH (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine more ... CTD PMID:17498763 Th Mouse (S)-nicotine increases expression ISO TH (Homo sapiens) 6480464 Nicotine results in increased expression of TH mRNA; Nicotine results in increased expression of TH more ... CTD PMID:17498763 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]; 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the more ... CTD PMID:16402076|PMID:16725203|PMID:18573265|PMID:19199078|PMID:19594327|PMID:19653878|PMID:19948168|PMID:20230807|PMID:23747572|PMID:23754278|PMID:23933227|PMID:23943375|PMID:25406165|PMID:25968939|PMID:27044752|PMID:28082123|PMID:28092019|PMID:28185818|PMID:31119595|PMID:32968928|PMID:34808223|PMID:36435477|PMID:37741537|PMID:38016618 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TH protein CTD PMID:30195017|PMID:38016618 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO TH (Homo sapiens) 6480464 PRKN protein inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH]; TXN protein inhibits more ... CTD PMID:24140863|PMID:25447324 Th Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression EXP 6480464 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA; more ... CTD PMID:15329391|PMID:16725203|PMID:17555550|PMID:18535749|PMID:18573265|PMID:19199078|PMID:19594327|PMID:20230807|PMID:21605582|PMID:21856379|PMID:23201480|PMID:23643664|PMID:23665943|PMID:23747572|PMID:23754278|PMID:23933227|PMID:23943375|PMID:24140863|PMID:25447324|PMID:25968939|PMID:27044752|PMID:27182044|PMID:27957685|PMID:28082123|PMID:28092019|PMID:28185818|PMID:28377118|PMID:30236862|PMID:31119595|PMID:32968928|PMID:34808223|PMID:36435477|PMID:37741537|PMID:38629493 Th Mouse 1-Naphthylacetylspermine multiple interactions ISO Th (Rattus norvegicus) 6480464 1-naphthylacetylspermine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in decreased expression of TH protein] CTD PMID:36775207 Th Mouse 15-deoxy-Delta(12,14)-prostaglandin J2 increases expression ISO Th (Rattus norvegicus) 6480464 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TH protein CTD PMID:15212945 Th Mouse 17beta-estradiol affects expression ISO Th (Rattus norvegicus) 6480464 Estradiol affects the expression of TH protein CTD PMID:16427766 Th Mouse 17beta-estradiol multiple interactions EXP 6480464 Estradiol inhibits the reaction [manganese chloride results in decreased expression of TH mRNA]; Estradiol inhibits more ... CTD PMID:29183790 Th Mouse 17beta-estradiol increases expression ISO TH (Homo sapiens) 6480464 Estradiol results in increased expression of TH mRNA CTD PMID:27271280|PMID:31614463 Th Mouse 17beta-estradiol multiple interactions ISO TH (Homo sapiens) 6480464 Estradiol promotes the reaction [ESR2 protein affects the expression of TH mRNA]; Estradiol results in more ... CTD PMID:20404318|PMID:27271280 Th Mouse 17beta-estradiol affects expression ISO TH (Homo sapiens) 6480464 Estradiol affects the expression of TH mRNA CTD PMID:14699072 Th Mouse 2',5'-Dideoxyadenosine multiple interactions ISO Th (Rattus norvegicus) 6480464 2',5'-dideoxyadenosine inhibits the reaction [epibatidine results in increased expression of TH mRNA] CTD PMID:15588622 Th Mouse 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO Th (Rattus norvegicus) 6480464 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of TH mRNA CTD PMID:29233657 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of more ... CTD PMID:19481886|PMID:19500377|PMID:21212295 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Th (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of TH mRNA CTD PMID:22808131 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TH protein CTD PMID:19481886 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TH mRNA; Tetrachlorodibenzodioxin results in increased expression of TH more ... CTD PMID:19500377|PMID:23296914|PMID:28029781 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine increases activity EXP 6480464 Tetrachlorodibenzodioxin results in increased activity of TH protein CTD PMID:19500377 Th Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases methylation EXP 6480464 Tetrachlorodibenzodioxin results in decreased methylation of TH gene CTD PMID:21212295 Th Mouse 2,4-D increases expression ISO Th (Rattus norvegicus) 6480464 2,4-Dichlorophenoxyacetic Acid results in increased expression of TH protein CTD PMID:16931444 Th Mouse 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO Th (Rattus norvegicus) 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the expression more ... CTD PMID:33571554 Th Mouse 3,4-dihydroxyphenylacetaldehyde affects binding ISO Th (Rattus norvegicus) 6480464 3,4-dihydroxyphenylacetaldehyde binds to TH protein CTD PMID:21238438 Th Mouse 3,4-dihydroxyphenylacetaldehyde decreases activity ISO Th (Rattus norvegicus) 6480464 3,4-dihydroxyphenylacetaldehyde results in decreased activity of TH protein CTD PMID:21514317 Th Mouse 3,4-dihydroxyphenylacetaldehyde multiple interactions ISO Th (Rattus norvegicus) 6480464 [3,4-dihydroxyphenylacetaldehyde results in decreased activity of TH protein] which results in decreased chemical synthesis of more ... CTD PMID:21514317 Th Mouse 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide multiple interactions EXP 6480464 Raclopride inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:16088948 Th Mouse 3,7-dihydropurine-6-thione multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:27435855 Th Mouse 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Th (Rattus norvegicus) 6480464 bisindolylmaleimide I inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TH mRNA]; bisindolylmaleimide I more ... CTD PMID:18992715 Th Mouse 3-Amino-1-methyl-5H-pyrido[4,3-b]indole decreases activity ISO Th (Rattus norvegicus) 6480464 3-amino-1-methyl-5H-pyrido(4,3-b)indole results in decreased activity of TH protein CTD PMID:2904812 Th Mouse 3-hydroxybutyric acid multiple interactions EXP 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression more ... CTD PMID:36435477 Th Mouse 3-methyladenine multiple interactions ISO Th (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [fenvalerate results in decreased expression of TH protein]; 3-methyladenine inhibits the more ... CTD PMID:28802652|PMID:31734597 Th Mouse 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:31187328 Th Mouse 4,4'-sulfonyldiphenol increases expression ISO Th (Rattus norvegicus) 6480464 bisphenol S results in increased expression of TH mRNA CTD PMID:26186136 Th Mouse 4,4'-sulfonyldiphenol affects methylation EXP 6480464 bisphenol S affects the methylation of TH exon CTD PMID:33297965 Th Mouse 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of TH mRNA CTD PMID:30951980 Th Mouse 4-phenylbutyric acid increases expression EXP 6480464 4-phenylbutyric acid results in increased expression of TH protein CTD PMID:21372141 Th Mouse 5-(2-chloroethyl)-4-methylthiazole multiple interactions EXP 6480464 Chlormethiazole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:1381816 Th Mouse 5-aza-2'-deoxycytidine increases expression ISO TH (Homo sapiens) 6480464 Decitabine results in increased expression of TH mRNA CTD PMID:23441691 Th Mouse 5-fluorouracil affects expression EXP 6480464 Fluorouracil affects the expression of TH protein CTD PMID:21296659 Th Mouse 6-propyl-2-thiouracil increases expression ISO Th (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of TH mRNA CTD PMID:25825206 Th Mouse 6-propyl-2-thiouracil decreases expression ISO Th (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of TH mRNA CTD PMID:33150595 Th Mouse 6-propyl-2-thiouracil increases methylation ISO Th (Rattus norvegicus) 6480464 Propylthiouracil results in increased methylation of TH promoter CTD PMID:33150595 Th Mouse 7-nitroindazole multiple interactions EXP 6480464 7-nitroindazole affects the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:8931477 Th Mouse 8-bromo-3',5'-cyclic GMP multiple interactions ISO Th (Rattus norvegicus) 6480464 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of more ... CTD PMID:16023617 Th Mouse 9-cis-retinoic acid decreases expression ISO TH (Homo sapiens) 6480464 Alitretinoin results in decreased expression of TH protein CTD PMID:36805303 Th Mouse acetic acid decreases expression EXP 6480464 Acetic Acid results in decreased expression of TH protein CTD PMID:21296659 Th Mouse acetylcholine increases expression ISO Th (Rattus norvegicus) 6480464 Acetylcholine results in increased expression of TH mRNA CTD PMID:29246838 Th Mouse acetylcholine multiple interactions ISO Th (Rattus norvegicus) 6480464 conotoxin AuIB inhibits the reaction [Acetylcholine results in increased expression of TH mRNA]; conotoxin AuIB more ... CTD PMID:29246838 Th Mouse acrylamide increases expression ISO Th (Rattus norvegicus) 6480464 Acrylamide results in increased expression of TH mRNA; Acrylamide results in increased expression of TH more ... CTD PMID:25943760 Th Mouse acrylonitrile multiple interactions ISO Th (Rattus norvegicus) 6480464 Acrylonitrile inhibits the reaction [3,3'-iminodipropionitrile results in increased expression of TH protein] CTD PMID:19244277 Th Mouse aflatoxin B1 increases methylation ISO TH (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of TH intron CTD PMID:30157460 Th Mouse Aflatoxin B2 alpha decreases methylation ISO TH (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of TH polyA tail CTD PMID:30157460 Th Mouse agmatine multiple interactions ISO Th (Rattus norvegicus) 6480464 Agmatine inhibits the reaction [Morphine results in increased expression of TH protein] CTD PMID:15541421 Th Mouse albiflorin affects expression ISO Th (Rattus norvegicus) 6480464 albiflorin affects the expression of TH CTD PMID:26475043 Th Mouse all-trans-retinoic acid multiple interactions ISO TH (Homo sapiens) 6480464 [Tretinoin co-treated with CNTF protein] results in increased expression of TH; [Tretinoin co-treated with SHH more ... CTD PMID:17017122|PMID:17085092|PMID:24101030|PMID:25614230|PMID:26210580|PMID:35594436 Th Mouse all-trans-retinoic acid decreases expression ISO TH (Homo sapiens) 6480464 Tretinoin results in decreased expression of TH protein CTD PMID:36805303 Th Mouse all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of TH mRNA CTD PMID:34627992 Th Mouse all-trans-retinoic acid multiple interactions EXP 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of TH mRNA; [mono-(2-ethylhexyl)phthalate co-treated with more ... CTD PMID:30951980|PMID:36189433 Th Mouse all-trans-retinoic acid increases expression ISO TH (Homo sapiens) 6480464 Tretinoin results in increased expression of TH mRNA; Tretinoin results in increased expression of TH more ... CTD PMID:15464216|PMID:25614230|PMID:26972010|PMID:35594436|PMID:37051183 Th Mouse AM-251 multiple interactions ISO Th (Rattus norvegicus) 6480464 AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA] CTD PMID:29113897 Th Mouse amentoflavone multiple interactions EXP 6480464 amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; amentoflavone inhibits the more ... CTD PMID:28185818 Th Mouse aminoguanidine multiple interactions EXP 6480464 pimagedine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein] CTD PMID:20455021 Th Mouse amitraz increases expression ISO Th (Rattus norvegicus) 6480464 amitraz results in increased expression of TH mRNA; amitraz results in increased expression of TH more ... CTD PMID:28463726 Th Mouse amitraz multiple interactions ISO Th (Rattus norvegicus) 6480464 Tamoxifen inhibits the reaction [amitraz results in increased expression of TH mRNA]; Tamoxifen inhibits the more ... CTD PMID:28463726 Th Mouse amitrole multiple interactions ISO Th (Rattus norvegicus) 6480464 Amitrole promotes the reaction [Sodium Chloride, Dietary results in increased expression of TH protein] CTD PMID:25891026 Th Mouse ammonium chloride affects expression ISO Th (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of TH mRNA CTD PMID:16483693 Th Mouse ammonium chloride decreases expression ISO Th (Rattus norvegicus) 6480464 Ammonium Chloride results in decreased expression of TH protein CTD PMID:16483693 Th Mouse amphetamine increases expression ISO Th (Rattus norvegicus) 6480464 Amphetamine results in increased expression of TH mRNA CTD PMID:16126238 Th Mouse amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of TH mRNA; Amphetamine results in increased expression of TH more ... CTD PMID:16916582|PMID:19059431 Th Mouse amphetamine decreases expression ISO Th (Rattus norvegicus) 6480464 Amphetamine results in decreased expression of TH protein CTD PMID:12468030|PMID:15836913|PMID:19145071 Th Mouse amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of TH protein CTD PMID:20620199 Th Mouse amphetamine multiple interactions EXP 6480464 PTN protein inhibits the reaction [Amphetamine results in decreased expression of TH protein] CTD PMID:20620199 Th Mouse apigenin multiple interactions ISO Th (Rattus norvegicus) 6480464 Apigenin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:28389404 Th Mouse apocynin decreases expression ISO Th (Rattus norvegicus) 6480464 acetovanillone results in decreased expression of TH mRNA CTD PMID:25217652 Th Mouse apocynin multiple interactions ISO Th (Rattus norvegicus) 6480464 acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein] CTD PMID:29859868 Th Mouse aprepitant multiple interactions ISO Th (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Aprepitant inhibits the reaction [Rotenone results in decreased expression of TH more ... CTD PMID:37224993 Th Mouse Aroclor 1254 multiple interactions ISO Th (Rattus norvegicus) 6480464 [aroclor 1242 co-treated with aroclor 1248 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] more ... CTD PMID:17324953|PMID:29879404 Th Mouse Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of TH protein CTD PMID:22094459 Th Mouse arsane multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH more ... CTD PMID:22704994 Th Mouse arsane increases expression EXP 6480464 Arsenic results in increased expression of TH protein CTD PMID:27413109 Th Mouse arsane decreases expression ISO Th (Rattus norvegicus) 6480464 Arsenic results in decreased expression of TH protein CTD PMID:22704994 Th Mouse arsenic atom decreases expression ISO Th (Rattus norvegicus) 6480464 Arsenic results in decreased expression of TH protein CTD PMID:22704994 Th Mouse arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of TH protein CTD PMID:27413109 Th Mouse arsenic atom multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH more ... CTD PMID:22704994 Th Mouse arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of TH mRNA CTD PMID:33053406 Th Mouse arsenite(3-) decreases expression ISO Th (Rattus norvegicus) 6480464 arsenite results in decreased expression of TH protein CTD PMID:29982692 Th Mouse arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of TH mRNA; arsenite results in decreased expression of TH more ... CTD PMID:29982692|PMID:33053406 Th Mouse arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of TH mRNA CTD PMID:23392890|PMID:23518225 Th Mouse arsenous acid decreases expression ISO TH (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of TH protein CTD PMID:11027660 Th Mouse arsenous acid multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of TH mRNA] CTD PMID:23392890 Th Mouse asiaticoside multiple interactions ISO Th (Rattus norvegicus) 6480464 [asiaticoside co-treated with Rotenone] results in decreased expression of TH protein CTD PMID:28238857 Th Mouse atrazine decreases expression ISO Th (Rattus norvegicus) 6480464 Atrazine results in decreased expression of TH mRNA; Atrazine results in decreased expression of TH more ... CTD PMID:14550852|PMID:23123945|PMID:24863964|PMID:26075868|PMID:26331294|PMID:30084861|PMID:34030342|PMID:34624533 Th Mouse atrazine decreases expression ISO TH (Homo sapiens) 6480464 Atrazine results in decreased expression of TH mRNA CTD PMID:34146662 Th Mouse baicalein multiple interactions EXP 6480464 baicalein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:27425033 Th Mouse baicalin multiple interactions EXP 6480464 baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TH protein] CTD PMID:38016618 Th Mouse Bardoxolone methyl multiple interactions EXP 6480464 bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of TH protein] CTD PMID:25637688 Th Mouse benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to TH promoter] CTD PMID:19654925 Th Mouse benzo[a]pyrene increases expression ISO TH (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of TH mRNA CTD PMID:35870112 Th Mouse benzo[a]pyrene affects methylation ISO TH (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TH promoter CTD PMID:27901495 Th Mouse benzo[a]pyrene decreases expression ISO Th (Rattus norvegicus) 6480464 Benzo(a)pyrene results in decreased expression of TH protein CTD PMID:28049045 Th Mouse beta-lapachone increases expression ISO TH (Homo sapiens) 6480464 beta-lapachone results in increased expression of TH mRNA CTD PMID:38218311 Th Mouse bicuculline multiple interactions ISO Th (Rattus norvegicus) 6480464 Bicuculline promotes the reaction [Reserpine affects the activity of TH protein]; Bicuculline promotes the reaction more ... CTD PMID:1981253 Th Mouse bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of TH mRNA CTD PMID:15674843 Th Mouse bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of TH protein CTD PMID:19481886 Th Mouse bis(2-ethylhexyl) phthalate multiple interactions ISO TH (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of TH more ... CTD PMID:33872906 Th Mouse bis(2-ethylhexyl) phthalate increases expression ISO Th (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of TH mRNA CTD PMID:29982774 Th Mouse bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of more ... CTD PMID:19481886 Th Mouse bisphenol A affects expression ISO Th (Rattus norvegicus) 6480464 bisphenol A affects the expression of TH protein CTD PMID:16427766 Th Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TH mRNA CTD PMID:30951980 Th Mouse bisphenol A multiple interactions ISO TH (Homo sapiens) 6480464 IGF1 protein inhibits the reaction [bisphenol A results in decreased expression of TH mRNA]; IGF1 more ... CTD PMID:27271280 Th Mouse bisphenol A decreases expression ISO TH (Homo sapiens) 6480464 bisphenol A results in decreased expression of TH mRNA; bisphenol A results in decreased expression more ... CTD PMID:27271280 Th Mouse bisphenol A increases expression ISO Th (Rattus norvegicus) 6480464 bisphenol A results in increased expression of TH mRNA CTD PMID:26141625 Th Mouse bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TH protein CTD PMID:19481886 Th Mouse bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of more ... CTD PMID:19481886|PMID:30951980 Th Mouse bisphenol A decreases expression ISO Th (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of TH mRNA; bisphenol A results in decreased expression more ... CTD PMID:16909604|PMID:17689037|PMID:25181051|PMID:34947998 Th Mouse bisphenol F decreases expression ISO Th (Rattus norvegicus) 6480464 4,4'-bisphenol F results in decreased expression of TH mRNA CTD PMID:26186136 Th Mouse bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of TH mRNA CTD PMID:30951980 Th Mouse BQ 123 multiple interactions ISO Th (Rattus norvegicus) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [EDN1 protein results in increased activity of TH protein]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits more ... CTD PMID:11911850 Th Mouse bromochloroacetic acid affects expression EXP 6480464 bromochloroacetic acid affects the expression of TH protein CTD PMID:21296659 Th Mouse bucladesine increases expression ISO Th (Rattus norvegicus) 6480464 Bucladesine results in increased expression of TH mRNA CTD PMID:19912776 Th Mouse butanal increases expression ISO TH (Homo sapiens) 6480464 butyraldehyde results in increased expression of TH mRNA CTD PMID:26079696 Th Mouse Butylparaben multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated more ... CTD PMID:34383603 Th Mouse cadmium atom increases expression ISO TH (Homo sapiens) 6480464 Cadmium results in increased expression of TH mRNA CTD PMID:21694771 Th Mouse cadmium dichloride decreases methylation ISO Th (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased methylation of TH promoter CTD PMID:22457795 Th Mouse cadmium dichloride increases expression ISO TH (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of TH mRNA CTD PMID:38174414 Th Mouse caffeine multiple interactions EXP 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of TH mRNA; Caffeine inhibits the reaction more ... CTD PMID:20230807|PMID:7996441 Th Mouse calcitriol multiple interactions ISO TH (Homo sapiens) 6480464 [Calcitriol co-treated with VDR protein] results in increased expression of TH mRNA; [Calcitriol co-treated with more ... CTD PMID:26210580 Th Mouse calcitriol decreases expression ISO Th (Rattus norvegicus) 6480464 Calcitriol results in decreased expression of TH protein CTD PMID:32147540 Th Mouse cannabidiol multiple interactions EXP 6480464 [Cannabidiol co-treated with Naltrexone] results in decreased expression of TH mRNA; Cannabidiol inhibits the reaction more ... CTD PMID:29624642|PMID:29859012 Th Mouse carmustine increases activity ISO Th (Rattus norvegicus) 6480464 Carmustine results in increased activity of TH protein CTD PMID:14670008 Th Mouse carmustine increases expression ISO Th (Rattus norvegicus) 6480464 Carmustine results in increased expression of TH mRNA; Carmustine results in increased expression of TH more ... CTD PMID:14670008 Th Mouse carnosic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:25446857 Th Mouse Carnosol multiple interactions EXP 6480464 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone inhibits the reaction [carnosol results in increased expression of TH protein]; carnosol inhibits the more ... CTD PMID:17047462 Th Mouse Carnosol increases expression EXP 6480464 carnosol results in increased expression of TH protein CTD PMID:17047462 Th Mouse carvedilol multiple interactions ISO Th (Rattus norvegicus) 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of TH protein] CTD PMID:22413959 Th Mouse carvedilol decreases expression ISO Th (Rattus norvegicus) 6480464 carvedilol results in decreased expression of TH mRNA; carvedilol results in decreased expression of TH more ... CTD PMID:20359859 Th Mouse chelerythrine multiple interactions ISO Th (Rattus norvegicus) 6480464 chelerythrine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TH mRNA]; chelerythrine inhibits the more ... CTD PMID:18992715 Th Mouse chitosan multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH more ... CTD PMID:22704994 Th Mouse Chloralose multiple interactions ISO Th (Rattus norvegicus) 6480464 [Nitroprusside co-treated with Urethane co-treated with Chloralose] results in increased expression of TH protein CTD PMID:12088752 Th Mouse chlorisondamine multiple interactions ISO Th (Rattus norvegicus) 6480464 Chlorisondamine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine promotes the more ... CTD PMID:1714554 Th Mouse chlorisondamine increases expression ISO Th (Rattus norvegicus) 6480464 Chlorisondamine results in increased expression of TH mRNA CTD PMID:1714554 Th Mouse chlorpyrifos increases expression ISO Th (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of TH mRNA CTD PMID:18812211 Th Mouse chlorpyrifos increases expression ISO TH (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of TH mRNA; Chlorpyrifos results in increased expression of TH more ... CTD PMID:34259569 Th Mouse chlorpyrifos multiple interactions ISO TH (Homo sapiens) 6480464 CDH8 protein affects the reaction [Chlorpyrifos results in increased expression of TH protein] CTD PMID:34259569 Th Mouse chlorpyrifos decreases expression ISO TH (Homo sapiens) 6480464 Chlorpyrifos results in decreased expression of TH protein CTD PMID:24793810 Th Mouse chlorpyrifos decreases expression ISO Th (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of TH protein CTD PMID:22714038|PMID:29859868 Th Mouse chlorpyrifos multiple interactions ISO Th (Rattus norvegicus) 6480464 acetovanillone analog inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein]; Acetylcysteine inhibits more ... CTD PMID:22714038|PMID:29859868 Th Mouse cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of TH mRNA CTD PMID:15464296|PMID:15471895 Th Mouse clonidine multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which more ... CTD PMID:19067675 Th Mouse clonidine (amino form) multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which more ... CTD PMID:19067675 Th Mouse clonidine (imino form) multiple interactions ISO Th (Rattus norvegicus) 6480464 [Clonidine results in decreased activity of and results in decreased expression of TH protein] which more ... CTD PMID:19067675 Th Mouse clozapine decreases activity ISO Th (Rattus norvegicus) 6480464 Clozapine results in decreased activity of TH protein CTD PMID:15983997 Th Mouse clozapine multiple interactions ISO Th (Rattus norvegicus) 6480464 Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein] CTD PMID:15983997 Th Mouse clozapine increases expression ISO Th (Rattus norvegicus) 6480464 Clozapine results in increased expression of TH protein CTD PMID:17028028 Th Mouse clozapine decreases expression ISO Th (Rattus norvegicus) 6480464 Clozapine results in decreased expression of TH mRNA; Clozapine results in decreased expression of TH more ... CTD PMID:12645084|PMID:15983997 Th Mouse clozapine increases activity EXP 6480464 Clozapine results in increased activity of TH protein CTD PMID:16415089 Th Mouse clozapine multiple interactions EXP 6480464 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine promotes the reaction [[Clozapine results in increased activity of TH protein] which results in more ... CTD PMID:16402076|PMID:16415089 Th Mouse cobalt dichloride multiple interactions EXP 6480464 [cobaltous chloride co-treated with Y 27632] results in increased expression of TH protein CTD PMID:16772336 Th Mouse cobalt dichloride increases expression ISO Th (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of TH mRNA CTD PMID:9458725 Th Mouse cocaine affects expression ISO Th (Rattus norvegicus) 6480464 Cocaine affects the expression of TH protein CTD PMID:12787079 Th Mouse cocaine decreases phosphorylation EXP 6480464 Cocaine results in decreased phosphorylation of TH protein CTD PMID:23499958 Th Mouse cocaine multiple interactions EXP 6480464 resveratrol promotes the reaction [Cocaine results in decreased phosphorylation of TH protein] CTD PMID:23499958 Th Mouse cocaine increases expression ISO Th (Rattus norvegicus) 6480464 Cocaine results in increased expression of TH protein CTD PMID:18992788 Th Mouse cocaine multiple interactions ISO Th (Rattus norvegicus) 6480464 Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results more ... CTD PMID:20729865 Th Mouse cocaine decreases expression ISO Th (Rattus norvegicus) 6480464 Cocaine results in decreased expression of TH protein CTD PMID:11391778 Th Mouse colforsin daropate hydrochloride multiple interactions ISO Th (Rattus norvegicus) 6480464 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased expression of TH mRNA]; bisindolylmaleimide I inhibits more ... CTD PMID:18992715 Th Mouse colforsin daropate hydrochloride increases expression ISO TH (Homo sapiens) 6480464 Colforsin results in increased expression of TH protein CTD PMID:34897981 Th Mouse colforsin daropate hydrochloride increases activity ISO Th (Rattus norvegicus) 6480464 Colforsin results in increased activity of TH protein CTD PMID:9288946 Th Mouse colforsin daropate hydrochloride increases expression ISO Th (Rattus norvegicus) 6480464 Colforsin results in increased expression of TH mRNA; Colforsin results in increased expression of TH more ... CTD PMID:14550852|PMID:18992715 Th Mouse copper atom multiple interactions EXP 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased expression of TH more ... CTD PMID:36775208 Th Mouse copper atom decreases expression EXP 6480464 Copper results in decreased expression of TH protein CTD PMID:37717680 Th Mouse copper(0) multiple interactions EXP 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased expression of TH more ... CTD PMID:36775208 Th Mouse copper(0) decreases expression EXP 6480464 Copper results in decreased expression of TH protein CTD PMID:37717680 Th Mouse copper(II) sulfate multiple interactions EXP 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased expression of TH more ... CTD PMID:20184101|PMID:36775208 Th Mouse copper(II) sulfate decreases expression ISO Th (Rattus norvegicus) 6480464 Copper Sulfate results in decreased expression of TH mRNA CTD PMID:18369385 Th Mouse corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of TH protein CTD PMID:28186389 Th Mouse Cuprizon decreases expression ISO Th (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of TH mRNA CTD PMID:27523638 Th Mouse curcumin multiple interactions ISO Th (Rattus norvegicus) 6480464 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH more ... CTD PMID:19631675|PMID:22704994|PMID:27966075 Th Mouse curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:31187328 Th Mouse curcumin multiple interactions ISO TH (Homo sapiens) 6480464 Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:30463061 Th Mouse cyanazine increases expression ISO Th (Rattus norvegicus) 6480464 cyanazine results in increased expression of TH protein CTD PMID:14550852 Th Mouse cyanocob(III)alamin multiple interactions ISO Th (Rattus norvegicus) 6480464 Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein] CTD PMID:38049026 Th Mouse cyclosporin A decreases methylation ISO TH (Homo sapiens) 6480464 Cyclosporine results in decreased methylation of TH promoter CTD PMID:27989131 Th Mouse cyhalothrin decreases expression ISO Th (Rattus norvegicus) 6480464 cyhalothrin results in decreased expression of TH mRNA; cyhalothrin results in decreased expression of TH more ... CTD PMID:22366556|PMID:28495607|PMID:36126889 Th Mouse cypermethrin decreases expression ISO Th (Rattus norvegicus) 6480464 cypermethrin results in decreased expression of TH mRNA; cypermethrin results in decreased expression of TH more ... CTD PMID:26115703 Th Mouse cytarabine decreases expression ISO TH (Homo sapiens) 6480464 Cytarabine results in decreased expression of TH protein CTD PMID:21198554 Th Mouse dabigatran multiple interactions ISO Th (Rattus norvegicus) 6480464 Dabigatran inhibits the reaction [Rotenone results in decreased expression of TH mRNA] CTD PMID:28585189 Th Mouse DDE multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated more ... CTD PMID:34383603 Th Mouse desferrioxamine B increases expression ISO Th (Rattus norvegicus) 6480464 Deferoxamine results in increased expression of TH mRNA CTD PMID:9458725 Th Mouse desipramine multiple interactions ISO Th (Rattus norvegicus) 6480464 Desipramine inhibits the reaction [Reserpine results in increased expression of TH mRNA] CTD PMID:1717808 Th Mouse dexamethasone increases expression ISO Th (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of TH protein CTD PMID:14550852 Th Mouse dexamethasone decreases expression ISO Th (Rattus norvegicus) 6480464 Dexamethasone results in decreased expression of TH mRNA CTD PMID:11072875 Th Mouse diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of TH mRNA CTD PMID:23392890|PMID:23518225 Th Mouse diarsenic trioxide multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of TH mRNA] CTD PMID:23392890 Th Mouse diarsenic trioxide decreases expression ISO TH (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of TH protein CTD PMID:11027660 Th Mouse diazinon increases expression ISO Th (Rattus norvegicus) 6480464 Diazinon results in increased expression of TH mRNA CTD PMID:17452286|PMID:18812211 Th Mouse dichlorvos increases activity ISO Th (Rattus norvegicus) 6480464 Dichlorvos results in increased activity of TH protein CTD PMID:12186780 Th Mouse dichlorvos multiple interactions ISO Th (Rattus norvegicus) 6480464 Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein] CTD PMID:12186780 Th Mouse dieldrin increases expression ISO Th (Rattus norvegicus) 6480464 Dieldrin results in increased expression of TH mRNA CTD PMID:18812211 Th Mouse diethyldithiocarbamic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 Ditiocarb results in decreased expression of and results in increased phosphorylation of TH protein CTD PMID:22874009 Th Mouse dioxygen increases expression ISO Th (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of TH mRNA CTD PMID:10486562|PMID:11577072|PMID:15225644 Th Mouse dipyridamole decreases expression ISO Th (Rattus norvegicus) 6480464 Dipyridamole results in decreased expression of TH protein CTD PMID:17568153 Th Mouse dopamine increases chemical synthesis ISO TH (Homo sapiens) 6480464 TH protein results in increased chemical synthesis of Dopamine CTD PMID:19815691 Th Mouse dopamine affects abundance EXP 6480464 TH protein affects the abundance of Dopamine CTD PMID:10984662|PMID:8707341 Th Mouse dopamine increases chemical synthesis ISO Th (Rattus norvegicus) 6480464 TH protein results in increased chemical synthesis of Dopamine CTD PMID:10661506 Th Mouse dopamine affects abundance ISO Th (Rattus norvegicus) 6480464 TH affects the abundance of Dopamine CTD PMID:20615977 Th Mouse dopamine decreases activity ISO Th (Rattus norvegicus) 6480464 Dopamine results in decreased activity of TH protein CTD PMID:2884129 Th Mouse dopamine multiple interactions ISO Th (Rattus norvegicus) 6480464 1-phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene analog promotes the reaction [TH protein results in increased chemical synthesis of Dopamine]; [1-phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene more ... CTD PMID:10661506|PMID:11113527|PMID:19067675|PMID:20729865|PMID:24743698|PMID:2884129 Th Mouse dopamine affects chemical synthesis EXP 6480464 TH protein affects the chemical synthesis of Dopamine CTD PMID:9822156 Th Mouse dopamine multiple interactions EXP 6480464 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine promotes the reaction [[Clozapine results in increased activity of TH protein] which results in more ... CTD PMID:10984662|PMID:16402076|PMID:16415089|PMID:9822156 Th Mouse dopaminechrome (enol form) decreases expression ISO Th (Rattus norvegicus) 6480464 aminochrome 1 results in decreased expression of TH protein CTD PMID:29588162 Th Mouse edaravone multiple interactions ISO Th (Rattus norvegicus) 6480464 Edaravone inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:27108097 Th Mouse elemental selenium increases activity ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased activity of TH protein CTD PMID:11113527 Th Mouse elemental selenium increases expression ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased expression of TH mRNA CTD PMID:11113527 Th Mouse elemental selenium multiple interactions ISO Th (Rattus norvegicus) 6480464 [Selenium deficiency results in increased activity of TH protein] which results in increased chemical synthesis more ... CTD PMID:11113527 Th Mouse enzacamene multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated more ... CTD PMID:34383603 Th Mouse epibatidine multiple interactions ISO Th (Rattus norvegicus) 6480464 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [epibatidine results in increased expression of TH more ... CTD PMID:15588622 Th Mouse epibatidine increases expression ISO Th (Rattus norvegicus) 6480464 epibatidine results in increased expression of TH mRNA CTD PMID:15588622 Th Mouse ethanol multiple interactions ISO Th (Rattus norvegicus) 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of TH protein] CTD PMID:22413959 Th Mouse ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of TH protein CTD PMID:26747301|PMID:34808223 Th Mouse ethanol multiple interactions EXP 6480464 Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in more ... CTD PMID:26747301|PMID:34590183 Th Mouse ethanol increases expression ISO Th (Rattus norvegicus) 6480464 Ethanol results in increased expression of TH protein CTD PMID:22413959 Th Mouse fasudil multiple interactions ISO Th (Rattus norvegicus) 6480464 [[propionic acid co-treated with fasudil] affects the susceptibility to Rotenone] which results in increased expression more ... CTD PMID:32481507 Th Mouse fenvalerate multiple interactions ISO Th (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [fenvalerate results in decreased expression of TH protein]; SB 203580 inhibits more ... CTD PMID:31734597 Th Mouse fenvalerate decreases expression ISO Th (Rattus norvegicus) 6480464 fenvalerate results in decreased expression of TH protein CTD PMID:31734597 Th Mouse ferrostatin-1 multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]; ferrostatin-1 inhibits the more ... CTD PMID:36435477 Th Mouse fipronil decreases expression ISO TH (Homo sapiens) 6480464 fipronil results in decreased expression of TH protein CTD PMID:21296133 Th Mouse flavonoids increases expression ISO Th (Rattus norvegicus) 6480464 Flavonoids results in increased expression of TH mRNA CTD PMID:18035473 Th Mouse fluoxetine decreases expression EXP 6480464 Fluoxetine results in decreased expression of TH mRNA CTD PMID:20857517 Th Mouse fluoxetine affects expression ISO Th (Rattus norvegicus) 6480464 Fluoxetine affects the expression of TH CTD PMID:26475043 Th Mouse fluoxetine increases expression ISO Th (Rattus norvegicus) 6480464 Fluoxetine results in increased expression of TH mRNA CTD PMID:1351783|PMID:20626387 Th Mouse fluoxetine decreases expression ISO Th (Rattus norvegicus) 6480464 Fluoxetine results in decreased expression of TH mRNA CTD PMID:15936043 Th Mouse fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of TH mRNA CTD PMID:20374287 Th Mouse formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of TH protein CTD PMID:15064152 Th Mouse fructose increases expression EXP 6480464 Fructose results in increased expression of TH mRNA CTD PMID:16843071 Th Mouse ganglioside GM1 increases activity ISO Th (Rattus norvegicus) 6480464 G(M1) Ganglioside results in increased activity of TH protein CTD PMID:14552908 Th Mouse genistein affects expression ISO Th (Rattus norvegicus) 6480464 Genistein affects the expression of TH protein CTD PMID:16427766 Th Mouse genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein] CTD PMID:20455021 Th Mouse geraniol multiple interactions EXP 6480464 geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:23943375 Th Mouse ginkgetin multiple interactions EXP 6480464 ginkgetin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:25968939 Th Mouse ginsenoside Re multiple interactions EXP 6480464 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene more ... CTD PMID:29467000 Th Mouse ginsenoside Re multiple interactions ISO TH (Homo sapiens) 6480464 ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased more ... CTD PMID:25523949 Th Mouse glyburide multiple interactions EXP 6480464 Glyburide promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:16725203 Th Mouse glycidol decreases expression ISO Th (Rattus norvegicus) 6480464 glycidol results in decreased expression of TH mRNA CTD PMID:33150645 Th Mouse glycidol increases methylation ISO Th (Rattus norvegicus) 6480464 glycidol results in increased methylation of TH promoter CTD PMID:33150595 Th Mouse guanethidine decreases expression ISO Th (Rattus norvegicus) 6480464 Guanethidine results in decreased expression of TH protein CTD PMID:9460767 Th Mouse GW 1929 multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:27435855 Th Mouse haloperidol increases expression ISO Th (Rattus norvegicus) 6480464 Haloperidol results in increased expression of TH protein CTD PMID:17028028 Th Mouse heptachlor increases expression EXP 6480464 Heptachlor results in increased expression of TH protein CTD PMID:16112329 Th Mouse herbicide decreases expression ISO Th (Rattus norvegicus) 6480464 Herbicides results in decreased expression of TH mRNA CTD PMID:23123945 Th Mouse hydrogen peroxide multiple interactions ISO TH (Homo sapiens) 6480464 TH protein inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein] CTD PMID:19815691 Th Mouse hydrogen peroxide affects expression ISO Th (Rattus norvegicus) 6480464 Hydrogen Peroxide affects the expression of TH mRNA CTD PMID:9458725 Th Mouse hydrogen peroxide affects abundance ISO Th (Rattus norvegicus) 6480464 TH protein affects the abundance of Hydrogen Peroxide CTD PMID:9458725 Th Mouse hydrogen peroxide affects response to substance ISO TH (Homo sapiens) 6480464 TH protein affects the susceptibility to Hydrogen Peroxide CTD PMID:19815691 Th Mouse icariin multiple interactions ISO Th (Rattus norvegicus) 6480464 icariin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:31251943 Th Mouse idazoxan increases expression ISO Th (Rattus norvegicus) 6480464 Idazoxan results in increased expression of TH mRNA CTD PMID:1351783 Th Mouse imidacloprid multiple interactions ISO Th (Rattus norvegicus) 6480464 [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the more ... CTD PMID:29246838 Th Mouse imidacloprid increases expression ISO Th (Rattus norvegicus) 6480464 imidacloprid results in increased expression of TH mRNA; imidacloprid results in increased expression of TH more ... CTD PMID:29246838 Th Mouse juglone multiple interactions EXP 6480464 juglone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:23754278 Th Mouse ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [Maneb results in decreased expression of TH protein]; Ketoconazole inhibits the more ... CTD PMID:19594327|PMID:22334051 Th Mouse KT 5720 decreases expression ISO Th (Rattus norvegicus) 6480464 KT 5720 results in decreased expression of TH mRNA CTD PMID:18992715 Th Mouse KT 5720 multiple interactions ISO Th (Rattus norvegicus) 6480464 KT 5720 inhibits the reaction [Colforsin results in increased expression of TH mRNA]; KT 5720 more ... CTD PMID:18992715 Th Mouse L-ascorbic acid increases expression ISO Th (Rattus norvegicus) 6480464 Ascorbic Acid results in increased expression of TH mRNA; Ascorbic Acid results in increased expression more ... CTD PMID:15372504|PMID:18772553 Th Mouse L-ascorbic acid decreases expression ISO Th (Rattus norvegicus) 6480464 Ascorbic Acid results in decreased expression of TH protein CTD PMID:25891525 Th Mouse L-ascorbic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; more ... CTD PMID:18772553|PMID:25891525 Th Mouse L-ascorbic acid decreases expression EXP 6480464 Ascorbic Acid results in decreased expression of TH protein CTD PMID:22285708 Th Mouse lead(0) decreases expression EXP 6480464 Lead results in decreased expression of TH protein CTD PMID:21703292 Th Mouse linalool decreases expression ISO Th (Rattus norvegicus) 6480464 linalool results in decreased expression of TH mRNA CTD PMID:20536181 Th Mouse linuron multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated more ... CTD PMID:34383603 Th Mouse lipopolysaccharide decreases methylation EXP 6480464 Lipopolysaccharides results in decreased methylation of TH gene CTD PMID:21212295 Th Mouse lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of TH protein CTD PMID:29338785 Th Mouse lipopolysaccharide multiple interactions ISO Th (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased phosphorylation of and results in increased activity of TH protein CTD PMID:23483921 Th Mouse lipopolysaccharide multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of TH gene; VCE-003 analog inhibits the more ... CTD PMID:21212295|PMID:29338785 Th Mouse lithium atom multiple interactions ISO Th (Rattus norvegicus) 6480464 Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19149911 Th Mouse lithium hydride multiple interactions ISO Th (Rattus norvegicus) 6480464 Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19149911 Th Mouse lovastatin increases expression ISO TH (Homo sapiens) 6480464 Lovastatin results in increased expression of TH protein CTD PMID:20694854 Th Mouse lovastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse lovastatin increases expression EXP 6480464 Lovastatin results in increased expression of TH protein CTD PMID:20694854 Th Mouse lovastatin multiple interactions ISO TH (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [HU 211 results in decreased expression of TH mRNA] CTD PMID:18950629 Th Mouse malathion decreases expression EXP 6480464 Malathion results in decreased expression of TH protein CTD PMID:39798862 Th Mouse maneb decreases expression EXP 6480464 Maneb results in decreased expression of TH protein CTD PMID:22334051 Th Mouse maneb multiple interactions ISO Th (Rattus norvegicus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of TH; [Paraquat co-treated with Maneb] results more ... CTD PMID:24376148|PMID:29152652 Th Mouse maneb multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein]; more ... CTD PMID:11124998|PMID:18386188|PMID:20455021|PMID:20964710|PMID:22334051|PMID:24486957 Th Mouse manganese atom decreases expression ISO Th (Rattus norvegicus) 6480464 Manganese results in decreased expression of TH mRNA; Manganese results in decreased expression of TH more ... CTD PMID:16943606|PMID:19781568|PMID:20224926|PMID:20798247 Th Mouse manganese atom multiple interactions ISO Th (Rattus norvegicus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH more ... CTD PMID:38129942 Th Mouse manganese atom multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH more ... CTD PMID:34590183 Th Mouse manganese(0) decreases expression ISO Th (Rattus norvegicus) 6480464 Manganese results in decreased expression of TH mRNA; Manganese results in decreased expression of TH more ... CTD PMID:16943606|PMID:19781568|PMID:20224926|PMID:20798247 Th Mouse manganese(0) multiple interactions ISO Th (Rattus norvegicus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH more ... CTD PMID:38129942 Th Mouse manganese(0) multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH more ... CTD PMID:34590183 Th Mouse manganese(II) chloride multiple interactions ISO Th (Rattus norvegicus) 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH more ... CTD PMID:21310168|PMID:23604964|PMID:38129942 Th Mouse manganese(II) chloride decreases expression ISO TH (Homo sapiens) 6480464 manganese chloride results in decreased expression of TH mRNA CTD PMID:27913844 Th Mouse manganese(II) chloride increases methylation ISO TH (Homo sapiens) 6480464 manganese chloride results in increased methylation of TH gene CTD PMID:27913844 Th Mouse manganese(II) chloride decreases expression ISO Th (Rattus norvegicus) 6480464 manganese chloride results in decreased expression of TH protein CTD PMID:20798247|PMID:23604964|PMID:30118795 Th Mouse manganese(II) chloride multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH more ... CTD PMID:24969583|PMID:29183790|PMID:29778792|PMID:34590183 Th Mouse manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of TH mRNA; manganese chloride results in decreased expression more ... CTD PMID:24969583|PMID:28539244|PMID:29183790|PMID:29778792 Th Mouse manganese(II) chloride increases expression ISO Th (Rattus norvegicus) 6480464 manganese chloride results in increased expression of TH mRNA; manganese chloride results in increased expression more ... CTD PMID:12106697 Th Mouse manganese(II) chloride decreases activity ISO Th (Rattus norvegicus) 6480464 manganese chloride results in decreased activity of TH protein CTD PMID:21310168 Th Mouse manganese(II) sulfate decreases expression ISO Th (Rattus norvegicus) 6480464 manganese sulfate results in decreased expression of TH mRNA CTD PMID:16943606 Th Mouse melatonin multiple interactions ISO Th (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Melatonin inhibits the more ... CTD PMID:18289173|PMID:19409439 Th Mouse melatonin multiple interactions ISO TH (Homo sapiens) 6480464 [Melatonin co-treated with ortho-topolin riboside] results in decreased expression of TH mRNA CTD PMID:38325522 Th Mouse melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]; Melatonin inhibits the more ... CTD PMID:20964710|PMID:24969583|PMID:34808223 Th Mouse mephedrone multiple interactions EXP 6480464 Ethanol promotes the reaction [mephedrone results in decreased expression of TH protein] CTD PMID:26747301 Th Mouse mephedrone decreases expression ISO Th (Rattus norvegicus) 6480464 mephedrone results in decreased expression of TH protein CTD PMID:25817894 Th Mouse mephedrone decreases expression EXP 6480464 mephedrone results in decreased expression of TH protein CTD PMID:26747301 Th Mouse mercaptopurine multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:27435855 Th Mouse metformin multiple interactions ISO Th (Rattus norvegicus) 6480464 Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TH more ... CTD PMID:35085591 Th Mouse methamphetamine decreases expression ISO TH (Homo sapiens) 6480464 Methamphetamine results in decreased expression of TH protein CTD PMID:16622715 Th Mouse methamphetamine multiple interactions ISO TH (Homo sapiens) 6480464 ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased more ... CTD PMID:25523949 Th Mouse methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of TH mRNA; Methamphetamine results in decreased expression of TH more ... CTD PMID:12871582|PMID:16088948|PMID:18277051|PMID:20722968|PMID:21151937|PMID:21867746|PMID:22329540|PMID:22512859|PMID:24072398|PMID:26283213|PMID:28919515|PMID:29467000|PMID:31422080|PMID:32278788|PMID:32768653|PMID:33359793|PMID:8931477 Th Mouse methamphetamine decreases activity EXP 6480464 Methamphetamine results in decreased activity of TH protein CTD PMID:1381816|PMID:22512859|PMID:7996441|PMID:9655613|PMID:9765353 Th Mouse methamphetamine affects expression ISO Th (Rattus norvegicus) 6480464 Methamphetamine affects the expression of TH mRNA CTD PMID:24042092 Th Mouse methamphetamine decreases expression ISO Th (Rattus norvegicus) 6480464 Methamphetamine results in decreased expression of TH protein CTD PMID:10773198|PMID:15276877|PMID:19149911|PMID:19409439|PMID:19442829|PMID:28661099|PMID:9739098 Th Mouse methamphetamine decreases activity ISO Th (Rattus norvegicus) 6480464 Methamphetamine results in decreased activity of TH protein CTD PMID:2579200 Th Mouse methamphetamine multiple interactions ISO Th (Rattus norvegicus) 6480464 diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Lithium inhibits more ... CTD PMID:15276877|PMID:19149911|PMID:19409439|PMID:19442829 Th Mouse methamphetamine affects response to substance EXP 6480464 TH protein affects the susceptibility to Methamphetamine CTD PMID:9822156 Th Mouse methamphetamine multiple interactions EXP 6480464 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene more ... CTD PMID:10984662|PMID:1381816|PMID:16088948|PMID:21151937|PMID:22329540|PMID:22512859|PMID:28919515|PMID:29467000|PMID:29782882|PMID:31422080|PMID:32278788|PMID:34082047|PMID:7996441|PMID:8931477|PMID:9655613|PMID:9822156 Th Mouse methoxychlor increases methylation ISO Th (Rattus norvegicus) 6480464 Methoxychlor results in increased methylation of TH gene CTD PMID:23303685 Th Mouse methyllycaconitine multiple interactions ISO TH (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine more ... CTD PMID:17498763 Th Mouse methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of TH mRNA CTD PMID:21385734 Th Mouse methylmercury chloride multiple interactions EXP 6480464 3,9-bis((ethylthio)methyl)-K-252a inhibits the reaction [methylmercuric chloride results in decreased expression of TH mRNA] CTD PMID:21385734 Th Mouse methylphenidate decreases expression EXP 6480464 Methylphenidate results in decreased expression of TH mRNA CTD PMID:22470460 Th Mouse mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse mevalonic acid multiple interactions ISO TH (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] CTD PMID:20694854 Th Mouse mifepristone decreases expression ISO TH (Homo sapiens) 6480464 Mifepristone results in decreased expression of TH mRNA CTD PMID:17584828 Th Mouse mifepristone multiple interactions ISO Th (Rattus norvegicus) 6480464 Mifepristone inhibits the reaction [Monocrotophos results in increased activity of TH protein] CTD PMID:22305719 Th Mouse minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:38189626 Th Mouse misonidazole increases activity EXP 6480464 Misonidazole results in increased activity of TH protein CTD PMID:2875048 Th Mouse misonidazole increases expression EXP 6480464 Misonidazole results in increased expression of TH protein CTD PMID:2875048 Th Mouse mono(2-ethylhexyl) phthalate decreases expression ISO Th (Rattus norvegicus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of TH mRNA CTD PMID:21145954 Th Mouse mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TH mRNA CTD PMID:36189433 Th Mouse mono(2-ethylhexyl) phthalate multiple interactions ISO TH (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of TH more ... CTD PMID:33872906 Th Mouse mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of TH mRNA CTD PMID:22401849 Th Mouse monocrotophos multiple interactions ISO Th (Rattus norvegicus) 6480464 Mifepristone inhibits the reaction [Monocrotophos results in increased activity of TH protein] CTD PMID:22305719 Th Mouse monocrotophos increases activity ISO Th (Rattus norvegicus) 6480464 Monocrotophos results in increased activity of TH protein CTD PMID:22305719 Th Mouse monosodium L-glutamate decreases expression ISO Th (Rattus norvegicus) 6480464 Sodium Glutamate results in decreased expression of TH mRNA CTD PMID:1980722 Th Mouse monosodium L-glutamate decreases activity ISO Th (Rattus norvegicus) 6480464 Sodium Glutamate results in decreased activity of TH protein CTD PMID:1980722 Th Mouse montelukast multiple interactions ISO Th (Rattus norvegicus) 6480464 montelukast inhibits the reaction [Rotenone results in increased expression of TH protein] CTD PMID:30222980 Th Mouse morphine multiple interactions ISO Th (Rattus norvegicus) 6480464 [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction more ... CTD PMID:15541421|PMID:24398105|PMID:25308750|PMID:25643298 Th Mouse morphine decreases expression ISO Th (Rattus norvegicus) 6480464 Morphine results in decreased expression of TH protein CTD PMID:26386147 Th Mouse morphine multiple interactions EXP 6480464 [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein; CRHR1 gene mutant form more ... CTD PMID:25582704 Th Mouse morphine increases phosphorylation ISO Th (Rattus norvegicus) 6480464 Morphine deficiency results in increased phosphorylation of TH protein CTD PMID:24398105 Th Mouse morphine increases expression ISO Th (Rattus norvegicus) 6480464 Morphine results in increased expression of TH protein CTD PMID:15541421 Th Mouse N(gamma)-nitro-L-arginine methyl ester decreases expression EXP 6480464 NG-Nitroarginine Methyl Ester results in decreased expression of TH protein CTD PMID:31187328 Th Mouse N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Th (Rattus norvegicus) 6480464 [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3, Clostridium botulinum] inhibits the reaction [imidacloprid results in increased expression more ... CTD PMID:18992715|PMID:29246838 Th Mouse N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases expression ISO Th (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of TH mRNA CTD PMID:18992715 Th Mouse N-acetyl-L-cysteine multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; more ... CTD PMID:22714038|PMID:25891525 Th Mouse N-acetyl-L-cysteine decreases expression ISO Th (Rattus norvegicus) 6480464 Acetylcysteine results in decreased expression of TH protein CTD PMID:25891525 Th Mouse N-ethyl-N-nitrosourea increases mutagenesis ISO Th (Rattus norvegicus) 6480464 Ethylnitrosourea results in increased mutagenesis of TH gene CTD PMID:16495775 Th Mouse N-ethylmaleimide multiple interactions ISO Th (Rattus norvegicus) 6480464 Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein] CTD PMID:15983997 Th Mouse N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression more ... CTD PMID:20184101|PMID:30165626|PMID:31187328|PMID:36435477 Th Mouse N-methyl-4-phenylpyridinium increases expression ISO TH (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of TH mRNA CTD PMID:24810058 Th Mouse N-methyl-4-phenylpyridinium decreases expression ISO TH (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA; 1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:26364587|PMID:30463061 Th Mouse N-methyl-4-phenylpyridinium multiple interactions ISO TH (Homo sapiens) 6480464 BMP2 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]; Curcumin inhibits more ... CTD PMID:20007850|PMID:26364587|PMID:30463061 Th Mouse N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA; 1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:20007850|PMID:23665943|PMID:26056851|PMID:26558463|PMID:30165626|PMID:31187328|PMID:36435477 Th Mouse N-methyl-4-phenylpyridinium decreases expression ISO Th (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA; 1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:19794909|PMID:23201480|PMID:27435855|PMID:31430510 Th Mouse N-methyl-4-phenylpyridinium multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:19794909|PMID:27435855|PMID:31430510 Th Mouse N-methyl-4-phenylpyridinium decreases activity EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased activity of TH protein CTD PMID:20184101 Th Mouse N-nitrosodiethylamine multiple interactions ISO Th (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TH mRNA CTD PMID:20360939 Th Mouse N-nitrosodiethylamine multiple interactions EXP 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TH gene CTD PMID:23968726 Th Mouse naloxone multiple interactions ISO Th (Rattus norvegicus) 6480464 [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction more ... CTD PMID:24398105|PMID:25308750 Th Mouse naloxone multiple interactions EXP 6480464 [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein; CRHR1 gene mutant form more ... CTD PMID:25582704 Th Mouse naloxone increases phosphorylation ISO Th (Rattus norvegicus) 6480464 Naloxone results in increased phosphorylation of TH protein CTD PMID:24398105 Th Mouse naltrexone multiple interactions EXP 6480464 [Cannabidiol co-treated with Naltrexone] results in decreased expression of TH mRNA CTD PMID:29859012 Th Mouse nickel atom increases expression ISO Th (Rattus norvegicus) 6480464 Nickel results in increased expression of TH mRNA CTD PMID:18812211 Th Mouse nickel dichloride multiple interactions ISO TH (Homo sapiens) 6480464 nickel chloride inhibits the reaction [Tretinoin results in increased expression of TH protein] CTD PMID:25614230 Th Mouse nicotine multiple interactions ISO Th (Rattus norvegicus) 6480464 [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the more ... CTD PMID:29246838 Th Mouse nicotine increases expression ISO Th (Rattus norvegicus) 6480464 Nicotine results in increased expression of TH mRNA; Nicotine results in increased expression of TH more ... CTD PMID:29246838 Th Mouse nicotine multiple interactions EXP 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of TH mRNA; [Nicotine co-treated with polylactic more ... CTD PMID:19594327|PMID:20230807|PMID:23933227|PMID:28082123 Th Mouse nicotine multiple interactions ISO TH (Homo sapiens) 6480464 [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine more ... CTD PMID:17498763 Th Mouse nicotine increases expression ISO TH (Homo sapiens) 6480464 Nicotine results in increased expression of TH mRNA; Nicotine results in increased expression of TH more ... CTD PMID:17498763 Th Mouse nimodipine multiple interactions ISO Th (Rattus norvegicus) 6480464 Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein] CTD PMID:12186780 Th Mouse nitroprusside multiple interactions ISO Th (Rattus norvegicus) 6480464 [Nitroprusside co-treated with Urethane co-treated with Chloralose] results in increased expression of TH protein; Nitroprusside more ... CTD PMID:12088752|PMID:16023617 Th Mouse nitroprusside increases expression ISO Th (Rattus norvegicus) 6480464 Nitroprusside results in increased expression of TH protein CTD PMID:12088752 Th Mouse Nookatone multiple interactions ISO Th (Rattus norvegicus) 6480464 nootkatone inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:35833337 Th Mouse Norbinaltorphimine multiple interactions EXP 6480464 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene more ... CTD PMID:29467000 Th Mouse olanzapine multiple interactions ISO Th (Rattus norvegicus) 6480464 olanzapine inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:15276877 Th Mouse oleuropein multiple interactions EXP 6480464 oleuropein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:36774383 Th Mouse oridonin multiple interactions ISO Th (Rattus norvegicus) 6480464 oridonin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH mRNA] CTD PMID:31430510 Th Mouse Ortho-topolin riboside multiple interactions ISO TH (Homo sapiens) 6480464 [Melatonin co-treated with ortho-topolin riboside] results in decreased expression of TH mRNA CTD PMID:38325522 Th Mouse oxidopamine decreases expression ISO Th (Rattus norvegicus) 6480464 Oxidopamine results in decreased expression of TH mRNA; Oxidopamine results in decreased expression of TH more ... CTD PMID:11730701|PMID:12585172|PMID:14696016|PMID:15703272|PMID:16480889|PMID:17222394|PMID:17933546|PMID:20232137|PMID:20623773|PMID:21088802|PMID:22842585|PMID:24486959|PMID:25129099|PMID:25446857|PMID:28802652|PMID:33571554|PMID:34302886|PMID:9460767 Th Mouse oxidopamine affects response to substance ISO TH (Homo sapiens) 6480464 TH protein affects the susceptibility to Oxidopamine CTD PMID:19815691 Th Mouse oxidopamine multiple interactions ISO TH (Homo sapiens) 6480464 TH protein inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein] CTD PMID:19815691 Th Mouse oxidopamine multiple interactions EXP 6480464 LY 344864 inhibits the reaction [Oxidopamine results in decreased expression of TH protein]; PRKN protein more ... CTD PMID:16914382|PMID:23518299|PMID:29057453 Th Mouse oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of TH mRNA; Oxidopamine results in decreased expression of TH more ... CTD PMID:15899244|PMID:16914382|PMID:17803225|PMID:23518299|PMID:29057453 Th Mouse oxidopamine multiple interactions ISO Th (Rattus norvegicus) 6480464 2-chloro-5-hydroxyphenylglycine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the expression more ... CTD PMID:12585172|PMID:15659429|PMID:16480889|PMID:22842585|PMID:25129099|PMID:25446857|PMID:28802652|PMID:33571554|PMID:34302886 Th Mouse P(1),P(4)-bis(5'-adenosyl) tetraphosphate multiple interactions ISO Th (Rattus norvegicus) 6480464 diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19442829 Th Mouse paracetamol multiple interactions ISO Th (Rattus norvegicus) 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated more ... CTD PMID:34383603 Th Mouse paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of TH protein CTD PMID:22334051|PMID:27919828|PMID:36108500|PMID:38189626 Th Mouse paraquat multiple interactions ISO TH (Homo sapiens) 6480464 MT2A protein inhibits the reaction [Paraquat results in increased expression of TH mRNA] CTD PMID:34623211 Th Mouse paraquat affects expression EXP 6480464 Paraquat affects the expression of TH protein CTD PMID:28428137 Th Mouse paraquat decreases expression ISO Th (Rattus norvegicus) 6480464 Paraquat results in decreased expression of TH mRNA; Paraquat results in decreased expression of TH more ... CTD PMID:16190885|PMID:20553223|PMID:24521700|PMID:25947082|PMID:28467894|PMID:32060784|PMID:34655599|PMID:35339517 Th Mouse paraquat increases expression ISO TH (Homo sapiens) 6480464 Paraquat results in increased expression of TH protein CTD PMID:26498265 Th Mouse paraquat increases activity ISO Th (Rattus norvegicus) 6480464 Paraquat results in increased activity of TH protein CTD PMID:24743698 Th Mouse paraquat multiple interactions ISO Th (Rattus norvegicus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of TH; [Paraquat co-treated with Maneb] results more ... CTD PMID:20553223|PMID:24376148|PMID:24743698|PMID:29152652|PMID:32060784|PMID:34655599|PMID:35339517 Th Mouse paraquat multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein]; more ... CTD PMID:11124998|PMID:16321246|PMID:18386188|PMID:20455021|PMID:20964710|PMID:22334051|PMID:24486957|PMID:27919828|PMID:28428137|PMID:38189626 Th Mouse pentanal decreases expression ISO TH (Homo sapiens) 6480464 pentanal results in decreased expression of TH mRNA CTD PMID:26079696 Th Mouse perfluorodecanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated more ... CTD PMID:34371090 Th Mouse perfluorododecanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated more ... CTD PMID:34371090 Th Mouse perfluorononanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated more ... CTD PMID:34371090 Th Mouse perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of TH mRNA CTD PMID:26686188 Th Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated more ... CTD PMID:34371090 Th Mouse perfluorooctanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated more ... CTD PMID:34371090 Th Mouse perfluoroundecanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated more ... CTD PMID:34371090 Th Mouse permethrin multiple interactions ISO Th (Rattus norvegicus) 6480464 Permethrin results in decreased expression of and results in decreased activity of TH protein CTD PMID:15461254 Th Mouse permethrin increases expression ISO Th (Rattus norvegicus) 6480464 Permethrin results in increased expression of TH mRNA CTD PMID:31175960 Th Mouse permethrin decreases expression ISO Th (Rattus norvegicus) 6480464 Permethrin results in decreased expression of TH mRNA CTD PMID:15461254 Th Mouse phencyclidine multiple interactions EXP 6480464 Phencyclidine inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:1381816 Th Mouse phencyclidine increases expression EXP 6480464 Phencyclidine results in increased expression of TH mRNA CTD PMID:12105081 Th Mouse Phenelzine increases expression ISO Th (Rattus norvegicus) 6480464 Phenelzine results in increased expression of TH mRNA CTD PMID:1351783 Th Mouse phenethyl caffeate multiple interactions ISO Th (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TH mRNA CTD PMID:20360939 Th Mouse phorbol 13-acetate 12-myristate multiple interactions ISO TH (Homo sapiens) 6480464 [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TH protein CTD PMID:24101030 Th Mouse phorbol 13-acetate 12-myristate increases expression ISO Th (Rattus norvegicus) 6480464 Tetradecanoylphorbol Acetate results in increased expression of TH mRNA CTD PMID:18992715 Th Mouse piperazine decreases expression ISO TH (Homo sapiens) 6480464 Piperazine analog results in decreased expression of TH protein CTD PMID:28874085 Th Mouse piperonyl butoxide multiple interactions EXP 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of TH gene CTD PMID:23968726 Th Mouse pirinixic acid multiple interactions ISO TH (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Th Mouse pregabalin affects expression EXP 6480464 Pregabalin affects the expression of TH mRNA CTD PMID:22017514 Th Mouse pregabalin increases expression EXP 6480464 Pregabalin results in increased expression of TH mRNA CTD PMID:22489711 Th Mouse probenecid multiple interactions EXP 6480464 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; more ... CTD PMID:19653878|PMID:25406165 Th Mouse progesterone decreases phosphorylation ISO Th (Rattus norvegicus) 6480464 Progesterone results in decreased phosphorylation of TH protein CTD PMID:18096660 Th Mouse progesterone decreases activity ISO Th (Rattus norvegicus) 6480464 Progesterone results in decreased activity of TH protein CTD PMID:18096660 Th Mouse propanal decreases expression ISO TH (Homo sapiens) 6480464 propionaldehyde results in decreased expression of TH mRNA CTD PMID:26079696 Th Mouse propionic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 [[propionic acid co-treated with fasudil] affects the susceptibility to Rotenone] which results in increased expression more ... CTD PMID:32481507 Th Mouse propionic acid increases expression ISO Th (Rattus norvegicus) 6480464 propionic acid results in increased expression of TH mRNA CTD PMID:32481507 Th Mouse propofol decreases expression EXP 6480464 Propofol results in decreased expression of TH protein CTD PMID:32612007 Th Mouse prothioconazole increases expression ISO TH (Homo sapiens) 6480464 prothioconazole results in increased expression of TH mRNA CTD PMID:35048155 Th Mouse purine-6-thiol multiple interactions ISO Th (Rattus norvegicus) 6480464 [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH more ... CTD PMID:27435855 Th Mouse pyrrolidine dithiocarbamate multiple interactions EXP 6480464 pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased more ... CTD PMID:34082047 Th Mouse pyrroloquinoline quinone multiple interactions ISO Th (Rattus norvegicus) 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:26276080|PMID:27108097 Th Mouse pyrroloquinoline quinone multiple interactions EXP 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:32860006 Th Mouse quercetin multiple interactions ISO Th (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Rotenone results in decreased activity of TH protein]; Quercetin inhibits the more ... CTD PMID:23357119|PMID:35337893 Th Mouse quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO Th (Rattus norvegicus) 6480464 isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 Th Mouse quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO Th (Rattus norvegicus) 6480464 isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 Th Mouse reserpine increases expression EXP 6480464 Reserpine results in increased expression of TH mRNA CTD PMID:8666980 Th Mouse reserpine increases activity ISO Th (Rattus norvegicus) 6480464 Reserpine results in increased activity of TH protein CTD PMID:1978789|PMID:2862954|PMID:2863328|PMID:2872048|PMID:2881815|PMID:8369965 Th Mouse reserpine increases expression ISO Th (Rattus norvegicus) 6480464 Reserpine results in increased expression of TH mRNA; Reserpine results in increased expression of TH more ... CTD PMID:11438978|PMID:1350653|PMID:1359376|PMID:1676830|PMID:1687822|PMID:1687976|PMID:1698642|PMID:1705056|PMID:1714554|PMID:1717808|PMID:1970845|PMID:1976760|PMID:1978789|PMID:1981253|PMID:2568627|PMID:2862954|PMID:2863328|PMID:2872048|PMID:2881815|PMID:2882513|PMID:2883324|PMID:2903502|PMID:7478180|PMID:7532593|PMID:7545485|PMID:7616203|PMID:7911764|PMID:8369965|PMID:9210518|PMID:9691425 Th Mouse reserpine decreases expression ISO Th (Rattus norvegicus) 6480464 Reserpine results in decreased expression of TH mRNA CTD PMID:20504635 Th Mouse reserpine affects activity ISO Th (Rattus norvegicus) 6480464 Reserpine affects the activity of TH protein CTD PMID:1981253 Th Mouse reserpine increases stability ISO Th (Rattus norvegicus) 6480464 Reserpine results in increased stability of TH mRNA CTD PMID:11161478 Th Mouse reserpine multiple interactions ISO Th (Rattus norvegicus) 6480464 Bicuculline promotes the reaction [Reserpine affects the activity of TH protein]; Bicuculline promotes the reaction more ... CTD PMID:11438978|PMID:1687822|PMID:1714554|PMID:1717808|PMID:1981253 Th Mouse resveratrol multiple interactions EXP 6480464 resveratrol promotes the reaction [Cocaine results in decreased phosphorylation of TH protein] CTD PMID:23499958 Th Mouse resveratrol multiple interactions ISO Th (Rattus norvegicus) 6480464 Resveratrol inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:34302886 Th Mouse resveratrol multiple interactions ISO TH (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of TH mRNA CTD PMID:23557933 Th Mouse rimonabant increases activity ISO Th (Rattus norvegicus) 6480464 Rimonabant results in increased activity of TH protein CTD PMID:15882845 Th Mouse rimonabant multiple interactions ISO Th (Rattus norvegicus) 6480464 Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]; Rimonabant inhibits more ... CTD PMID:10700552|PMID:15882845|PMID:9188039 Th Mouse risperidone increases expression ISO Th (Rattus norvegicus) 6480464 Risperidone results in increased expression of TH protein CTD PMID:17028028 Th Mouse rotenone multiple interactions EXP 6480464 baicalein inhibits the reaction [Rotenone results in decreased expression of TH protein]; carnosol inhibits the more ... CTD PMID:17047462|PMID:27425033|PMID:32860006|PMID:35589691|PMID:36774383 Th Mouse rotenone decreases activity ISO Th (Rattus norvegicus) 6480464 Rotenone results in decreased activity of TH protein CTD PMID:35187747|PMID:35337893 Th Mouse rotenone increases expression ISO Th (Rattus norvegicus) 6480464 Rotenone results in increased expression of TH protein CTD PMID:30222980 Th Mouse rotenone decreases expression ISO Th (Rattus norvegicus) 6480464 Rotenone results in decreased expression of TH mRNA; Rotenone results in decreased expression of TH more ... CTD PMID:12385818|PMID:15790535|PMID:16490285|PMID:18289173|PMID:18579341|PMID:23098804|PMID:23357119|PMID:25430725|PMID:25446674|PMID:26075822|PMID:26276080|PMID:26446018|PMID:27108097|PMID:28238857|PMID:28389404|PMID:28585189|PMID:31251943|PMID:32088201|PMID:32392329|PMID:33279658|PMID:33515431|PMID:34182063|PMID:35728354|PMID:35833337|PMID:37224993 Th Mouse rotenone multiple interactions ISO Th (Rattus norvegicus) 6480464 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Docosahexaenoic Acids inhibits the reaction [Rotenone results in decreased expression of more ... CTD PMID:15790535|PMID:16490285|PMID:18289173|PMID:23357119|PMID:25446674|PMID:26075822|PMID:26276080|PMID:26446018|PMID:27108097|PMID:28238857|PMID:28389404|PMID:28585189|PMID:30222980|PMID:31251943|PMID:32481507|PMID:33279658|PMID:33515431|PMID:34182063|PMID:35187747|PMID:35337893|PMID:35728354|PMID:35833337|PMID:37224993 Th Mouse rotenone increases response to substance ISO Th (Rattus norvegicus) 6480464 TH protein results in increased susceptibility to Rotenone CTD PMID:14622122 Th Mouse rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of TH protein CTD PMID:17047462|PMID:27425033|PMID:29458170|PMID:32860006|PMID:35589691|PMID:36774383 Th Mouse rottlerin multiple interactions ISO Th (Rattus norvegicus) 6480464 rottlerin inhibits the reaction [manganese chloride results in decreased activity of TH protein] CTD PMID:21310168 Th Mouse rottlerin multiple interactions EXP 6480464 [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased more ... CTD PMID:22512859 Th Mouse rutin multiple interactions ISO Th (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 Th Mouse salubrinal multiple interactions ISO Th (Rattus norvegicus) 6480464 salubrinal inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:26446018 Th Mouse saxagliptin multiple interactions ISO Th (Rattus norvegicus) 6480464 saxagliptin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:25446674 Th Mouse SB 203580 multiple interactions ISO Th (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [fenvalerate results in decreased expression of TH protein]; SB 203580 more ... CTD PMID:31734597|PMID:9288946 Th Mouse SCH 23390 multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein]; SCH 23390 more ... CTD PMID:16088948|PMID:30922767 Th Mouse selenium atom increases activity ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased activity of TH protein CTD PMID:11113527 Th Mouse selenium atom increases expression ISO Th (Rattus norvegicus) 6480464 Selenium deficiency results in increased expression of TH mRNA CTD PMID:11113527 Th Mouse selenium atom multiple interactions ISO Th (Rattus norvegicus) 6480464 [Selenium deficiency results in increased activity of TH protein] which results in increased chemical synthesis more ... CTD PMID:11113527 Th Mouse simazine decreases expression ISO Th (Rattus norvegicus) 6480464 Simazine results in decreased expression of TH protein CTD PMID:14550852 Th Mouse simazine decreases expression EXP 6480464 Simazine results in decreased expression of TH mRNA; Simazine results in decreased expression of TH more ... CTD PMID:34936186 Th Mouse simazine affects expression EXP 6480464 Simazine affects the expression of TH mRNA; Simazine affects the expression of TH protein CTD PMID:29137186 Th Mouse simazine increases expression EXP 6480464 Simazine results in increased expression of TH mRNA; Simazine results in increased expression of TH more ... CTD PMID:27513680|PMID:32822773 Th Mouse simazine multiple interactions EXP 6480464 LMX1A protein promotes the reaction [Simazine results in increased expression of TH protein] CTD PMID:32822773 Th Mouse sodium arsenite multiple interactions EXP 6480464 [sodium arsenite affects the localization of NR4A2 protein] inhibits the reaction [NR4A2 protein results in more ... CTD PMID:23283970 Th Mouse sodium arsenite increases expression ISO Th (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of TH protein CTD PMID:25179238 Th Mouse sodium arsenite decreases expression ISO Th (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of TH protein CTD PMID:19631675|PMID:27966075|PMID:30051311 Th Mouse sodium arsenite multiple interactions ISO Th (Rattus norvegicus) 6480464 Curcumin inhibits the reaction [sodium arsenite results in decreased expression of TH protein]; SB 203580 more ... CTD PMID:19631675|PMID:27966075|PMID:9288946 Th Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of TH protein CTD PMID:27413109 Th Mouse sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of TH mRNA CTD PMID:19121333|PMID:23283970|PMID:37682722 Th Mouse sodium benzoate increases expression EXP 6480464 Sodium Benzoate results in increased expression of TH mRNA; Sodium Benzoate results in increased expression more ... CTD PMID:34113786 Th Mouse sodium benzoate multiple interactions EXP 6480464 CREB1 protein promotes the reaction [Sodium Benzoate results in increased expression of TH protein]; GDNF more ... CTD PMID:31119595|PMID:34113786 Th Mouse sodium chloride increases expression ISO Th (Rattus norvegicus) 6480464 Sodium Chloride results in increased expression of TH mRNA CTD PMID:10613505 Th Mouse Sophoricoside multiple interactions EXP 6480464 sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:37741537 Th Mouse spiperone multiple interactions ISO Th (Rattus norvegicus) 6480464 Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of more ... CTD PMID:20729865 Th Mouse streptozocin multiple interactions ISO Th (Rattus norvegicus) 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein; Metformin inhibits the more ... CTD PMID:35085591|PMID:38049026 Th Mouse streptozocin decreases expression ISO Th (Rattus norvegicus) 6480464 Streptozocin results in decreased expression of TH protein CTD PMID:38049026 Th Mouse sulforaphane multiple interactions EXP 6480464 sulforaphane inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:23518299 Th Mouse sulpiride multiple interactions ISO Th (Rattus norvegicus) 6480464 Sulpiride inhibits the reaction [Dopamine results in decreased activity of TH protein]; Sulpiride inhibits the more ... CTD PMID:18289173|PMID:2884129 Th Mouse sulpiride multiple interactions EXP 6480464 Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein] CTD PMID:30922767 Th Mouse sulpiride increases activity ISO Th (Rattus norvegicus) 6480464 Sulpiride results in increased activity of TH protein CTD PMID:2884129 Th Mouse Talipexole dihydrochloride multiple interactions EXP 6480464 talipexole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:9655613 Th Mouse tamoxifen multiple interactions EXP 6480464 Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of TH mRNA]; Tamoxifen inhibits more ... CTD PMID:29183790 Th Mouse tamoxifen decreases expression ISO Th (Rattus norvegicus) 6480464 Tamoxifen results in decreased expression of TH mRNA; Tamoxifen results in decreased expression of TH more ... CTD PMID:28463726 Th Mouse tamoxifen multiple interactions ISO Th (Rattus norvegicus) 6480464 Tamoxifen inhibits the reaction [amitraz results in increased expression of TH mRNA]; Tamoxifen inhibits the more ... CTD PMID:28463726 Th Mouse taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [arsenic trioxide results in decreased expression of TH mRNA] CTD PMID:23392890 Th Mouse telmisartan multiple interactions EXP 6480464 telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; telmisartan inhibits the more ... CTD PMID:23747572 Th Mouse testosterone decreases expression ISO Th (Rattus norvegicus) 6480464 Testosterone results in decreased expression of TH protein CTD PMID:11883789 Th Mouse topiramate increases expression EXP 6480464 topiramate results in increased expression of TH mRNA CTD PMID:22489711 Th Mouse topiramate affects expression EXP 6480464 topiramate affects the expression of TH mRNA CTD PMID:22017514 Th Mouse trichloroethene decreases expression ISO Th (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of TH protein CTD PMID:33636387 Th Mouse trichloroethene increases expression ISO Th (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of TH mRNA CTD PMID:33387578 Th Mouse triprolidine multiple interactions ISO Th (Rattus norvegicus) 6480464 Triprolidine inhibits the reaction [1-phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene analog promotes the reaction [TH protein results in increased chemical more ... CTD PMID:10661506 Th Mouse tris(2-butoxyethyl) phosphate affects expression ISO TH (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate affects the expression of TH mRNA CTD PMID:29024780 Th Mouse urethane multiple interactions ISO Th (Rattus norvegicus) 6480464 [Nitroprusside co-treated with Urethane co-treated with Chloralose] results in increased expression of TH protein CTD PMID:12088752 Th Mouse valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of TH mRNA CTD PMID:17963808 Th Mouse valproic acid increases methylation ISO Th (Rattus norvegicus) 6480464 Valproic Acid results in increased methylation of TH promoter CTD PMID:33150595 Th Mouse valproic acid multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of TH mRNA]; Valproic more ... CTD PMID:29778792 Th Mouse valproic acid affects expression ISO TH (Homo sapiens) 6480464 Valproic Acid affects the expression of TH mRNA CTD PMID:25979313 Th Mouse valproic acid increases expression ISO Th (Rattus norvegicus) 6480464 Valproic Acid results in increased expression of TH mRNA; Valproic Acid results in increased expression more ... CTD PMID:18976638 Th Mouse valproic acid decreases expression ISO Th (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of TH mRNA; Valproic Acid results in decreased expression more ... CTD PMID:18976638|PMID:33150595 Th Mouse valproic acid multiple interactions ISO Th (Rattus norvegicus) 6480464 CREB1 protein affects the reaction [Valproic Acid results in increased expression of TH mRNA]; Valproic more ... CTD PMID:18976638|PMID:19149911 Th Mouse valproic acid affects expression ISO Th (Rattus norvegicus) 6480464 Valproic Acid affects the expression of TH protein CTD PMID:19460635 Th Mouse vitamin D decreases expression ISO Th (Rattus norvegicus) 6480464 Vitamin D deficiency results in decreased expression of TH mRNA; Vitamin D deficiency results in more ... CTD PMID:28365874 Th Mouse vitamin E multiple interactions ISO Th (Rattus norvegicus) 6480464 [Ascorbic Acid co-treated with Vitamin E] results in increased expression of TH protein CTD PMID:18772553 Th Mouse vorinostat decreases expression ISO TH (Homo sapiens) 6480464 vorinostat results in decreased expression of TH mRNA CTD PMID:27188386 Th Mouse WIN 55212-2 affects expression ISO Th (Rattus norvegicus) 6480464 (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH protein CTD PMID:29113897 Th Mouse WIN 55212-2 multiple interactions ISO Th (Rattus norvegicus) 6480464 AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA] CTD PMID:29113897 Th Mouse WIN 55212-2 multiple interactions EXP 6480464 (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:28092019 Th Mouse wortmannin multiple interactions EXP 6480464 wortmannin affects the reaction [HU 211 results in decreased expression of TH mRNA] CTD PMID:18950629 Th Mouse wortmannin multiple interactions ISO Th (Rattus norvegicus) 6480464 [wortmannin co-treated with manganese chloride] results in decreased expression of TH protein CTD PMID:23604964 Th Mouse Y-27632 multiple interactions EXP 6480464 [cobaltous chloride co-treated with Y 27632] results in increased expression of TH protein CTD PMID:16772336 Th Mouse zearalenone decreases expression ISO TH (Homo sapiens) 6480464 Zearalenone results in decreased expression of TH mRNA CTD PMID:24412706 Th Mouse zinc atom increases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in increased expression of TH protein CTD PMID:11165868 Th Mouse zinc atom multiple interactions ISO Th (Rattus norvegicus) 6480464 Paraquat promotes the reaction [Zinc results in decreased expression of TH protein]; Zinc promotes the more ... CTD PMID:32060784 Th Mouse zinc atom decreases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in decreased expression of TH protein CTD PMID:32060784 Th Mouse zinc sulfate multiple interactions ISO Th (Rattus norvegicus) 6480464 Paraquat promotes the reaction [Zinc Sulfate results in decreased expression of TH protein]; Zinc Sulfate more ... CTD PMID:20553223 Th Mouse zinc sulfate decreases expression ISO Th (Rattus norvegicus) 6480464 Zinc Sulfate results in decreased expression of TH protein CTD PMID:20553223 Th Mouse zinc(0) increases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in increased expression of TH protein CTD PMID:11165868 Th Mouse zinc(0) decreases expression ISO Th (Rattus norvegicus) 6480464 Zinc results in decreased expression of TH protein CTD PMID:32060784 Th Mouse zinc(0) multiple interactions ISO Th (Rattus norvegicus) 6480464 Paraquat promotes the reaction [Zinc results in decreased expression of TH protein]; Zinc promotes the more ... CTD PMID:32060784 Th Mouse zonisamide increases expression ISO TH (Homo sapiens) 6480464 zonisamide results in increased expression of TH mRNA; zonisamide results in increased expression of TH more ... CTD PMID:20196486 Th Mouse zonisamide multiple interactions EXP 6480464 [zonisamide co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] affects the activity of TH protein; zonisamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine more ... CTD PMID:19199078|PMID:19948168 Th Mouse zonisamide increases expression EXP 6480464 zonisamide results in increased expression of TH protein CTD PMID:19199078