Ighm (immunoglobulin heavy constant mu) - Rat Genome Database

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Gene: Ighm (immunoglobulin heavy constant mu) Mus musculus
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Symbol: Ighm
Name: immunoglobulin heavy constant mu
RGD ID: 11303086
MGI Page MGI
Description: Enables several functions, including antigen binding activity; identical protein binding activity; and immunoglobulin receptor binding activity. Involved in pre-B cell allelic exclusion. Acts upstream of or within several processes, including early endosome to late endosome transport; immunoglobulin mediated immune response; and positive regulation of B cell proliferation. Located in external side of plasma membrane; extracellular space; and perinuclear region of cytoplasm. Part of B cell receptor complex and immunoglobulin complex, circulating. Is active in cytoplasm. Is expressed in several structures, including brain; hemolymphoid system; intestine; and liver. Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in agammaglobulinemia 1. Orthologous to human IGHM (immunoglobulin heavy constant mu).
Type: gene (Ensembl: IG_C_gene)
RefSeq Status: VALIDATED
Previously known as: AI326478; Ig; Igh-; Igh-6; Igh-M; Igh6; Igm; muH
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912113,382,446 - 113,386,350 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12113,382,178 - 113,386,350 (-)EnsemblGRCm39 Ensembl
GRCm3812113,418,826 - 113,422,730 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12113,418,558 - 113,422,730 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712114,657,037 - 114,660,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera12114,602,986 - 114,613,710 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1262.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal antigen presentation  (IAGP)
abnormal B cell activation  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal B cell proliferation  (IAGP)
abnormal B lymphocyte antigen presentation  (IAGP)
abnormal B-1a B cell morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal complement pathway  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal follicular dendritic cell antigen presentation  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal immature B cell morphology  (IAGP)
abnormal immune serum protein physiology  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal lymphatic vessel morphology  (IAGP)
abnormal mature B cell morphology  (IAGP)
abnormal metallophilic macrophage morphology  (IAGP)
abnormal pancreatic islet morphology  (IAGP)
abnormal plasma cell differentiation  (IAGP)
abnormal PR interval  (IAGP)
abnormal respiratory system physiology  (IAGP)
abnormal response to infection  (IAGP)
abnormal skin condition  (IAGP)
abnormal spleen B cell follicle morphology  (IAGP)
abnormal spleen germinal center morphology  (IAGP)
abnormal spleen marginal sinus morphology  (IAGP)
abnormal spleen marginal zone macrophage morphology  (IAGP)
abnormal spleen marginal zone morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal spleen periarteriolar lymphoid sheath morphology  (IAGP)
abnormal spleen white pulp morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal T cell number  (IAGP)
abnormal T cell proliferation  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal tumor susceptibility  (IAGP)
absent B cells  (IAGP)
absent follicular dendritic cells  (IAGP)
absent immature B cells  (IAGP)
absent mature B cells  (IAGP)
arrested B cell differentiation  (IAGP)
cachexia  (IAGP)
cardiac fibrosis  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased B-1 B cell number  (IAGP)
decreased bone mineral density  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased compact bone thickness  (IAGP)
decreased compact bone volume  (IAGP)
decreased dendritic cell number  (IAGP)
decreased follicular B cell number  (IAGP)
decreased IgA level  (IAGP)
decreased IgE level  (IAGP)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG2a level  (IAGP)
decreased IgG2b level  (IAGP)
decreased IgG3 level  (IAGP)
decreased IgM level  (IAGP)
decreased immature B cell number  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased Peyer's patch number  (IAGP)
decreased plasma cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased retina photoreceptor cell number  (IAGP)
decreased spleen B cell follicle number  (IAGP)
decreased spleen weight  (IAGP)
decreased susceptibility to autoimmune diabetes  (IAGP)
decreased susceptibility to injury  (IAGP)
decreased susceptibility to systemic lupus erythematosus  (IAGP)
decreased susceptibility to type IV hypersensitivity reaction  (IAGP)
decreased T cell proliferation  (IAGP)
decreased trabecular bone thickness  (IAGP)
decreased transitional stage B cell number  (IAGP)
enlarged heart  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
heart inflammation  (IAGP)
impaired complement classical pathway  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell derived lymphoma incidence  (IAGP)
increased B cell number  (IAGP)
increased B cell proliferation  (IAGP)
increased B-1 B cell number  (IAGP)
increased cell proliferation  (IAGP)
increased circulating glucose level  (IAGP)
increased IgA level  (IAGP)
increased IgG2a level  (IAGP)
increased IgG3 level  (IAGP)
increased IgM level  (IAGP)
increased inflammatory response  (IAGP)
increased lymphoma incidence  (IAGP)
increased marginal zone B cell number  (IAGP)
increased osteoclast cell number  (IAGP)
increased plasma cell number  (IAGP)
increased pro-B cell number  (IAGP)
increased spleen germinal center number  (IAGP)
increased spleen white pulp amount  (IAGP)
increased susceptibility to autoimmune diabetes  (IAGP)
increased susceptibility to induced arthritis  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to Riboviria infection  (IAGP)
increased T cell number  (IAGP)
increased urine protein level  (IAGP)
insulitis  (IAGP)
kidney inflammation  (IAGP)
myocarditis  (IAGP)
no abnormal phenotype detected  (IAGP)
premature death  (IAGP)
retina photoreceptor degeneration  (IAGP)
small intestinal inflammation  (IAGP)
small lymph nodes  (IAGP)
small Peyer's patches  (IAGP)
thrombocytopenia  (IAGP)
thymus hypoplasia  (IAGP)
tubular nephritis  (IAGP)
References
Additional References at PubMed
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PMID:27688803   PMID:27701733   PMID:27729620   PMID:27763657   PMID:27806296   PMID:27859053   PMID:27899441   PMID:27903567   PMID:27918564   PMID:27920091   PMID:27924814   PMID:27940658  
PMID:27995616   PMID:28067900   PMID:28135254   PMID:28137874   PMID:28192375   PMID:28250159   PMID:28255084   PMID:28264908   PMID:28351982   PMID:28378742   PMID:28461496   PMID:28468798  
PMID:28607116   PMID:28615655   PMID:28652397   PMID:28698287   PMID:28746783   PMID:28747342   PMID:28768709   PMID:28827539   PMID:28848066   PMID:28923960   PMID:28931462   PMID:28948612  
PMID:28972091   PMID:28978474   PMID:29069606   PMID:29093061   PMID:29101311   PMID:29144460   PMID:29186687   PMID:29212910   PMID:29246441   PMID:29281837   PMID:29282308   PMID:29288200  
PMID:29288206   PMID:29312329   PMID:29335647   PMID:29337666   PMID:29364878   PMID:29367208   PMID:29389016   PMID:29396161   PMID:29449556   PMID:29467472   PMID:29476183   PMID:29507409  
PMID:29521626   PMID:29531165   PMID:29545260   PMID:29555915   PMID:29560109   PMID:29562201   PMID:29599140   PMID:29661828   PMID:29674392   PMID:29691398   PMID:29708507   PMID:29777029  
PMID:29805094   PMID:29847991   PMID:29866771   PMID:29866844   PMID:29904094   PMID:29907525   PMID:29969845   PMID:29975708   PMID:29996101   PMID:29999501   PMID:30009261   PMID:30022165  
PMID:30076099   PMID:30082831   PMID:30093657   PMID:30095974   PMID:30097565   PMID:30111869   PMID:30144035   PMID:30274972   PMID:30284926   PMID:30291028   PMID:30305329   PMID:30333825  
PMID:30335684   PMID:30336975   PMID:30374346   PMID:30429364   PMID:30538335   PMID:30567732   PMID:30635390   PMID:30643147   PMID:30643287   PMID:30700910   PMID:30728330   PMID:30772497  
PMID:30819965   PMID:30944247   PMID:30944260   PMID:31076359   PMID:31112525   PMID:31116977   PMID:31167928   PMID:31249364   PMID:31408003   PMID:31409776   PMID:31433298   PMID:31484732  
PMID:31552025   PMID:31554802   PMID:31575547   PMID:31579886   PMID:31586207   PMID:31591231   PMID:31636237   PMID:31641151   PMID:31665632   PMID:31775034   PMID:31792184   PMID:31819031  
PMID:31827095   PMID:31875850   PMID:31915378   PMID:31945014   PMID:31980486   PMID:31985756   PMID:32023467   PMID:32026472   PMID:32076265   PMID:32101465   PMID:32130409   PMID:32152506  
PMID:32193439   PMID:32205880   PMID:32213346   PMID:32213563   PMID:32253245   PMID:32325033   PMID:32503977   PMID:32572241   PMID:32619424   PMID:32655552   PMID:32737150   PMID:32773769  
PMID:32796905   PMID:32849530   PMID:32868930   PMID:32907369   PMID:32907933   PMID:32940605   PMID:32973802   PMID:32978280   PMID:33149299   PMID:33193409   PMID:33207194   PMID:33239388  
PMID:33249168   PMID:33270017   PMID:33293517   PMID:33378682   PMID:33432228   PMID:33497603   PMID:33531346   PMID:33531483   PMID:33597749   PMID:33724364   PMID:33883189   PMID:33952457  
PMID:33971183   PMID:34006859   PMID:34031614   PMID:34050029   PMID:34060477   PMID:34088745   PMID:34117110   PMID:34135064   PMID:34257370   PMID:34260908   PMID:34289373   PMID:34313733  
PMID:34369876   PMID:34413082   PMID:34433030   PMID:34469734   PMID:34608861   PMID:34621263   PMID:34626548   PMID:34795669   PMID:34852228   PMID:34852236   PMID:34868004   PMID:34871323  
PMID:34882194   PMID:34956189   PMID:35021101   PMID:35046933   PMID:35081372   PMID:35149532   PMID:35168003   PMID:35236989   PMID:35294793   PMID:35296858   PMID:35355990   PMID:35371001  
PMID:35451955   PMID:35493520   PMID:35537415   PMID:35584674   PMID:35636458   PMID:35696583   PMID:35705250   PMID:35720386   PMID:35768001   PMID:35794860   PMID:35830810   PMID:35856618  
PMID:35902665   PMID:36048017   PMID:36054664   PMID:36073543   PMID:36078100   PMID:36095971   PMID:36104343   PMID:36137543   PMID:36173678   PMID:36178806   PMID:36264674   PMID:36341713  
PMID:36426970   PMID:36427805   PMID:36458995   PMID:36475902   PMID:36512034   PMID:36658240   PMID:36662229   PMID:36883955   PMID:36888692   PMID:36961449   PMID:37033932   PMID:37081893  
PMID:37115935   PMID:37219943   PMID:37301910   PMID:37352357   PMID:37369341   PMID:37572655   PMID:37636058   PMID:37682538   PMID:37721965   PMID:37767784   PMID:38182585   PMID:38203534  
PMID:38242132   PMID:38359115   PMID:38458187   PMID:38492219   PMID:38536935   PMID:38772371  


Genomics

Comparative Map Data
Ighm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912113,382,446 - 113,386,350 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12113,382,178 - 113,386,350 (-)EnsemblGRCm39 Ensembl
GRCm3812113,418,826 - 113,422,730 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12113,418,558 - 113,422,730 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712114,657,037 - 114,660,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera12114,602,986 - 114,613,710 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1262.1NCBI
IGHM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814105,851,966 - 105,856,217 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14105,851,705 - 105,856,218 (-)EnsemblGRCh38hg38GRCh38
GRCh3714106,318,298 - 106,322,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614105,389,082 - 105,393,367 (-)NCBINCBI36Build 36hg18NCBI36
Celera1486,248,585 - 86,253,097 (-)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1486,451,068 - 86,455,319 (-)NCBIHuRef
CHM1_114106,188,922 - 106,193,173 (-)NCBICHM1_1
T2T-CHM13v2.014100,123,532 - 100,127,783 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in Ighm
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:287
Count of miRNA genes:248
Interacting mature miRNAs:269
Transcripts:ENSMUST00000103426, ENSMUST00000177715
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
39128213Lwq23_mliver weight QTL 10 (mouse)1280956708113383533Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
4141297Plyid_mPolymeric IgA dominance (mouse)Not determined109183385115885122Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
15092085Igly2_mIgG glycosylation 2, GP14 (mouse)12111737297119992757Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80956708113383533Mouse
15092083Igly5_mIgG glycosylation 5, GP20 (mouse)12113373605117830647Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286396075114831653Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80956708113383533Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
1558957Igan4_mIgA nephropathy 4 (mouse)Not determined12109750025119024949Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80956708113383533Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1280989143114989143Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_005838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB067781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB067797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC073553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF045497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF052834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF052835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF318418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF318462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF321953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF546751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI326478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ294737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY172397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY172497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY172900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY182736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB226392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG070287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M77137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z22061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000103426   ⟹   ENSMUSP00000100222
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12113,384,361 - 113,386,350 (-)Ensembl
GRCm38.p6 Ensembl12113,420,741 - 113,422,730 (-)Ensembl
Ensembl Acc Id: ENSMUST00000177715   ⟹   ENSMUSP00000136807
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12113,382,178 - 113,386,350 (-)Ensembl
GRCm38.p6 Ensembl12113,418,558 - 113,422,730 (-)Ensembl
Protein Sequences
GenBank Protein AAA38422 (Get FASTA)   NCBI Sequence Viewer  
  AAA51161 (Get FASTA)   NCBI Sequence Viewer  
  AAC04525 (Get FASTA)   NCBI Sequence Viewer  
  AAC08348 (Get FASTA)   NCBI Sequence Viewer  
  AAC08349 (Get FASTA)   NCBI Sequence Viewer  
  AAK01191 (Get FASTA)   NCBI Sequence Viewer  
  AAK19271 (Get FASTA)   NCBI Sequence Viewer  
  AAL92949 (Get FASTA)   NCBI Sequence Viewer  
  AAN62969 (Get FASTA)   NCBI Sequence Viewer  
  AAO18854 (Get FASTA)   NCBI Sequence Viewer  
  AAO18856 (Get FASTA)   NCBI Sequence Viewer  
  AAO18873 (Get FASTA)   NCBI Sequence Viewer  
  AAO18882 (Get FASTA)   NCBI Sequence Viewer  
  AAO18908 (Get FASTA)   NCBI Sequence Viewer  
  AAO18917 (Get FASTA)   NCBI Sequence Viewer  
  AAO18923 (Get FASTA)   NCBI Sequence Viewer  
  AAO18965 (Get FASTA)   NCBI Sequence Viewer  
  AAO18979 (Get FASTA)   NCBI Sequence Viewer  
  AAO18982 (Get FASTA)   NCBI Sequence Viewer  
  AAO18992 (Get FASTA)   NCBI Sequence Viewer  
  AAO19002 (Get FASTA)   NCBI Sequence Viewer  
  AAO19005 (Get FASTA)   NCBI Sequence Viewer  
  AAO19006 (Get FASTA)   NCBI Sequence Viewer  
  AAO19018 (Get FASTA)   NCBI Sequence Viewer  
  AAO19029 (Get FASTA)   NCBI Sequence Viewer  
  AAO19030 (Get FASTA)   NCBI Sequence Viewer  
  AAO19032 (Get FASTA)   NCBI Sequence Viewer  
  AAO19039 (Get FASTA)   NCBI Sequence Viewer  
  AAO19051 (Get FASTA)   NCBI Sequence Viewer  
  AAO19052 (Get FASTA)   NCBI Sequence Viewer  
  AAO19076 (Get FASTA)   NCBI Sequence Viewer  
  AAO19082 (Get FASTA)   NCBI Sequence Viewer  
  AAO19087 (Get FASTA)   NCBI Sequence Viewer  
  AAO19092 (Get FASTA)   NCBI Sequence Viewer  
  AAO23224 (Get FASTA)   NCBI Sequence Viewer  
  AAO23357 (Get FASTA)   NCBI Sequence Viewer  
  AAO23425 (Get FASTA)   NCBI Sequence Viewer  
  BAB63266 (Get FASTA)   NCBI Sequence Viewer  
  BAB63270 (Get FASTA)   NCBI Sequence Viewer  
  BAB63272 (Get FASTA)   NCBI Sequence Viewer  
  BAB63274 (Get FASTA)   NCBI Sequence Viewer  
  BAB63276 (Get FASTA)   NCBI Sequence Viewer  
  BAB63277 (Get FASTA)   NCBI Sequence Viewer  
  BAB63278 (Get FASTA)   NCBI Sequence Viewer  
  BAB63279 (Get FASTA)   NCBI Sequence Viewer  
  BAB63282 (Get FASTA)   NCBI Sequence Viewer  
  BAC40490 (Get FASTA)   NCBI Sequence Viewer  
  CAA24198 (Get FASTA)   NCBI Sequence Viewer  
  CAA24199 (Get FASTA)   NCBI Sequence Viewer  
  CAA24202 (Get FASTA)   NCBI Sequence Viewer  
  CAA24203 (Get FASTA)   NCBI Sequence Viewer  
  CAA24204 (Get FASTA)   NCBI Sequence Viewer  
  CAA27326 (Get FASTA)   NCBI Sequence Viewer  
  CAA80035 (Get FASTA)   NCBI Sequence Viewer  
  CAC20701 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000100222.2
  ENSMUSP00000136807.3
GenBank Protein P01872 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSMUSP00000136807   ⟸   ENSMUST00000177715
Ensembl Acc Id: ENSMUSP00000100222   ⟸   ENSMUST00000103426
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P04219-F1-model_v2 AlphaFold P04219 1-140 view protein structure
AF-P01872-F1-model_v2 AlphaFold P01872 1-454 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96448 AgrOrtholog
Ensembl Genes ENSMUSG00000076617 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000103426.3 UniProtKB/TrEMBL
  ENSMUST00000177715.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IgHV UniProtKB/TrEMBL
  Immune_Resp_Modulators UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96448 ENTREZGENE
NCBI Gene Ighm ENTREZGENE
PANTHER IG HEAVY CHAIN V REGION 1-62-3-RELATED UniProtKB/TrEMBL
  IMMUNOGLOBULIN HEAVY CHAIN UniProtKB/TrEMBL
  IMMUNOGLOBULIN HEAVY CONSTANT MU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAPASIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Ighm PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A075B5P6_MOUSE UniProtKB/TrEMBL
  A0A075B6A0_MOUSE UniProtKB/TrEMBL
  IGHM_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q924Q3_MOUSE UniProtKB/TrEMBL
  Q924Q6_MOUSE UniProtKB/TrEMBL
  Q924Q7_MOUSE UniProtKB/TrEMBL
  Q924Q8_MOUSE UniProtKB/TrEMBL
  Q924Q9_MOUSE UniProtKB/TrEMBL
  Q924R1_MOUSE UniProtKB/TrEMBL
  Q924R3_MOUSE UniProtKB/TrEMBL
  Q924R4_MOUSE UniProtKB/TrEMBL
  Q924R8_MOUSE UniProtKB/TrEMBL
UniProt Secondary P01873 UniProtKB/Swiss-Prot