Rxra (retinoid X receptor alpha) - Rat Genome Database

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Gene: Rxra (retinoid X receptor alpha) Mus musculus
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Symbol: Rxra
Name: retinoid X receptor alpha
RGD ID: 11250
MGI Page MGI
Description: Enables DNA binding activity; DNA-binding transcription factor activity; and transcription coactivator binding activity. Contributes to nuclear receptor activity and transcription cis-regulatory region binding activity. Involved in mRNA transcription by RNA polymerase II; positive regulation of thyroid hormone receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cardiac muscle tissue development; regulation of branching involved in prostate gland morphogenesis; and regulation of gene expression. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and sensory organ. Used to study congenital heart disease; dilated cardiomyopathy; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9530071D11Rik; Nr2b1; nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; RXR; RXR alpha 1; RXRalpha1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,566,457 - 27,653,331 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl227,566,452 - 27,652,969 (+)EnsemblGRCm39 Ensembl
GRCm38227,676,445 - 27,763,319 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,676,440 - 27,762,957 (+)EnsemblGRCm38mm10GRCm38
MGSCv37227,532,721 - 27,618,839 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36227,499,210 - 27,585,328 (+)NCBIMGSCv36mm8
Celera227,439,778 - 27,465,824 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-anisomycin  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
13-cis-retinal  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17beta-estradiol  (ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol  (ISO)
2-bromohexadecanoic acid  (EXP)
2-hydroxyphytanic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5,5'-tetraiodothyroacetic acid  (ISO)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nonylphenol  (EXP)
5-(2-chloroethyl)-4-methylthiazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinal  (ISO)
9-cis-retinoic acid  (EXP,ISO)
acetamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
alfacalcidol  (ISO)
all-cis-docosa-7,10,13,16-tetraenoic acid  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-acitretin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
alpha-linolenic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
aphidicolin  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arotinoid acid  (ISO)
arsenous acid  (EXP,ISO)
beauvericin  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-carotene  (ISO)
bexarotene  (ISO)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caesium atom  (ISO)
caffeine  (ISO)
calciol  (ISO)
calcitriol  (EXP,ISO)
Calphostin C  (ISO)
capsaicin  (ISO)
carnosic acid  (ISO)
cerivastatin  (ISO)
chloroacetaldehyde  (ISO)
chlorogenic acid  (ISO)
cholesterol  (ISO)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
Clofop  (ISO)
conjugated linoleic acid  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (EXP,ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dextran sulfate  (EXP)
Di-n-hexyl phthalate  (ISO)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (ISO)
dibutylstannane  (EXP,ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diheptyl phthalate  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (ISO)
Dimethyl phthalate  (ISO)
dimethyl sulfoxide  (EXP)
dimethylarsinous acid  (ISO)
diosgenin  (EXP)
dioxygen  (EXP,ISO)
dipentyl phthalate  (ISO)
dipropyl phthalate  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enniatin  (ISO)
epoxiconazole  (ISO)
equilin  (ISO)
ethanol  (EXP,ISO)
etodolac  (EXP)
etoposide  (ISO)
farnesol  (ISO)
fenofibrate  (ISO)
fentin chloride  (ISO)
fentin hydroxide  (ISO)
fenvalerate  (ISO)
fipronil  (ISO)
flurbiprofen  (ISO)
flutamide  (ISO)
fluvastatin  (ISO)
folic acid  (EXP)
fructose  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geranylgeraniol  (ISO)
glutathione  (EXP)
glycidol  (ISO)
griseofulvin  (EXP)
GW 1929  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
inulin  (EXP)
isotretinoin  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
leptomycin B  (ISO)
levofloxacin  (ISO)
linoleic acid  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (EXP,ISO)
menadione  (ISO)
menaquinone  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methoprene  (EXP,ISO)
methoxychlor  (ISO)
methyltestosterone  (ISO)
mevalonic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-dimethylformamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nitrofen  (ISO)
obeticholic acid  (ISO)
okadaic acid  (ISO)
oleic acid  (ISO)
orotic acid  (ISO)
Osajin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
penconazole  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
phthalic acid  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
pitavastatin  (ISO)
pitavastatin(1-)  (ISO)
PK-11195  (ISO)
poly(propylene imine) macromolecule  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (ISO)
prostaglandin J2  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (EXP)
rifampicin  (EXP,ISO)
Ro 41-5253  (ISO)
Rosavin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
selenium atom  (ISO)
senecionine  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sincalide  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
Sorbitan monooleate  (ISO)
sucrose  (ISO)
Sudan III  (ISO)
sulindac  (ISO)
tamibarotene  (ISO)
teniposide  (ISO)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thyroxine  (ISO)
tiratricol  (ISO)
titanium dioxide  (EXP)
tomelukast  (EXP)
tributylstannane  (EXP,ISO)
trichloroethene  (EXP)
triphenyl phosphate  (EXP,ISO)
triphenylphosphane oxide  (ISO)
triphenylstannane  (ISO)
troglitazone  (EXP,ISO)
uranium atom  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin D  (ISO)
zinc acetate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis involved in coronary vascular morphogenesis  (TAS)
axon regeneration  (ISO)
camera-type eye development  (IGI)
cardiac muscle cell differentiation  (TAS)
cardiac muscle cell proliferation  (IGI,IMP,TAS)
cell differentiation  (IBA)
cellular response to insulin stimulus  (ISO)
embryo implantation  (IGI)
female pregnancy  (ISO)
gene expression  (IMP)
heart development  (IMP,TAS)
heart morphogenesis  (TAS)
hormone-mediated signaling pathway  (ISO)
in utero embryonic development  (IGI)
liver development  (ISO)
maternal placenta development  (IGI)
mesenchyme development  (TAS)
midgut development  (ISO)
mRNA transcription by RNA polymerase II  (IDA,ISO,NAS)
negative regulation of cell population proliferation  (ISO)
negative regulation of gene expression  (TAS)
negative regulation of transcription by RNA polymerase II  (IBA,IGI,ISO)
peroxisome proliferator activated receptor signaling pathway  (ISO)
placenta development  (IMP,ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of bone mineralization  (NAS)
positive regulation of DNA-templated transcription  (IGI,ISO,TAS)
positive regulation of thyroid hormone receptor signaling pathway  (IDA,ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IGI,IMP,ISO,NAS)
positive regulation of translational initiation by iron  (IGI)
positive regulation of vitamin D receptor signaling pathway  (ISO)
regulation of branching involved in prostate gland morphogenesis  (IMP)
regulation of DNA-templated transcription  (IDA,ISO)
regulation of myelination  (ISO)
regulation of transcription by RNA polymerase II  (IGI)
response to ethanol  (ISO)
response to glucocorticoid  (ISO)
response to nutrient  (ISO)
response to organic cyclic compound  (ISO)
response to retinoic acid  (IBA,ISO)
response to selenium ion  (ISO)
response to vitamin A  (ISO)
response to vitamin D  (ISO)
retinoic acid receptor signaling pathway  (IBA,IDA,IMP,ISO)
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development  (IMP)
ventricular cardiac muscle cell differentiation  (IGI,IMP)
ventricular cardiac muscle tissue morphogenesis  (IMP)
visceral serous pericardium development  (TAS)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior eye segment morphology  (IAGP)
abnormal atrioventricular cushion morphology  (IAGP)
abnormal atrioventricular valve morphology  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cone electrophysiology  (IAGP)
abnormal conotruncal ridge morphology  (IAGP)
abnormal conotruncus septation  (IAGP)
abnormal cornea stroma morphology  (IAGP)
abnormal cricoid cartilage morphology  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal epidermis stratum corneum morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal eyelid morphology  (IAGP)
abnormal hair cycle anagen phase  (IAGP)
abnormal hair cycle telogen phase  (IAGP)
abnormal hair follicle melanin granule distribution  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair growth  (IAGP)
abnormal heart development  (IAGP)
abnormal heart left atrium morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal heart ventricle shape  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal Langerhans cell morphology  (IAGP)
abnormal macrophage activation involved in immune response  (IAGP)
abnormal melanosome morphology  (IAGP)
abnormal mitral valve morphology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal nephron morphology  (IAGP)
abnormal ocular fundus morphology  (IAGP)
abnormal optic disk morphology  (IAGP)
abnormal otic vesicle development  (IAGP)
abnormal pericardial cavity morphology  (IAGP)
abnormal pericardium morphology  (IAGP)
abnormal peritoneal macrophage morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal photoreceptor outer segment morphology  (IAGP)
abnormal piliary canal morphology  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal podocyte foot process morphology  (IAGP)
abnormal postnatal growth/weight/body size  (IAGP)
abnormal prostate gland branching morphogenesis  (IAGP)
abnormal prostate gland physiology  (IAGP)
abnormal regulatory T cell physiology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retina outer nuclear layer morphology  (IAGP)
abnormal retina pigment epithelium morphology  (IAGP)
abnormal retina pigmentation  (IAGP)
abnormal rod electrophysiology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin morphology  (IAGP)
abnormal T-helper 2 cell morphology  (IAGP)
abnormal tricuspid valve morphology  (IAGP)
abnormal truncus arteriosus septation  (IAGP)
abnormal vasculogenesis  (IAGP)
abnormal ventricle papillary muscle morphology  (IAGP)
absent Harderian gland  (IAGP)
absent sclera  (IAGP)
absent sublingual duct  (IAGP)
absent third pharyngeal arch artery  (IAGP)
albuminuria  (IAGP)
alopecia  (IAGP)
aortopulmonary window  (IAGP)
atrioventricular block  (IAGP)
complete atrioventricular septal defect  (IAGP)
congestive heart failure  (IAGP)
cornea opacity  (IAGP)
decreased cardiac output  (IAGP)
decreased cholesterol level  (IAGP)
decreased fetal size  (IAGP)
decreased heart left ventricle muscle contractility  (IAGP)
decreased heart left ventricle wall thickness  (IAGP)
decreased heart rate  (IAGP)
decreased heart right ventricle wall thickness  (IAGP)
decreased hepatocyte proliferation  (IAGP)
decreased retina photoreceptor cell number  (IAGP)
decreased ventral retina size  (IAGP)
delayed dark adaptation  (IAGP)
delayed hair appearance  (IAGP)
delayed hepatic development  (IAGP)
dermal cyst  (IAGP)
dermal hyperplasia  (IAGP)
dermatitis  (IAGP)
dilated heart right atrium  (IAGP)
dilated heart right ventricle  (IAGP)
dilated piliary canal  (IAGP)
diluted coat color  (IAGP)
disorganized outer root sheath cells  (IAGP)
disorganized photoreceptor outer segment  (IAGP)
distorted hair follicle pattern  (IAGP)
double outlet right ventricle  (IAGP)
dry skin  (IAGP)
ear inflammation  (IAGP)
edema  (IAGP)
embryonic growth retardation  (IAGP)
enlarged cervical lymph nodes  (IAGP)
enlarged kidney  (IAGP)
enlarged liver  (IAGP)
enlarged spleen  (IAGP)
epidermal hyperplasia  (IAGP)
expanded mesangial matrix  (IAGP)
failure of atrioventricular cushion closure  (IAGP)
fused podocyte foot processes  (IAGP)
glomerulonephritis  (IAGP)
hair follicle degeneration  (IAGP)
heart block  (IAGP)
hyperkeratosis  (IAGP)
impaired macrophage phagocytosis  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased anti-single stranded DNA antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased circulating creatine level  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased immunoglobulin level  (IAGP)
increased keratinocyte proliferation  (IAGP)
increased kidney weight  (IAGP)
increased leukocyte cell number  (IAGP)
increased mesangial cell number  (IAGP)
increased prostate intraepithelial neoplasia incidence  (IAGP)
increased renal glomerulus apoptosis  (IAGP)
increased renal glomerulus basement membrane thickness  (IAGP)
increased rhombomere 5 size  (IAGP)
increased urine protein level  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lymph node hyperplasia  (IAGP)
mitral valve atresia  (IAGP)
mitral valve stenosis  (IAGP)
mixed cellular infiltration to dermis  (IAGP)
muscular ventricular septal defect  (IAGP)
no abnormal phenotype detected  (IAGP)
optic disk coloboma  (IAGP)
pallor  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistent hyperplastic primary vitreous  (IAGP)
persistent truncus arteriosus  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality  (IAGP)
prostate gland epithelial hyperplasia  (IAGP)
pulmonary artery stenosis  (IAGP)
renal glomerulus hypertrophy  (IAGP)
retina pigment epithelium atrophy  (IAGP)
scaly skin  (IAGP)
shiny skin  (IAGP)
short photoreceptor outer segment  (IAGP)
skin edema  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
small liver  (IAGP)
thick dermal layer  (IAGP)
thick epidermis suprabasal layer  (IAGP)
thin hypodermis  (IAGP)
thin ventricular wall  (IAGP)
third pharyngeal arch hypoplasia  (IAGP)
trabecula carnea hypoplasia  (IAGP)
translucent skin  (IAGP)
ventral rotation of lens  (IAGP)
ventricular hypoplasia  (IAGP)
ventricular myocardium compact layer hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Expression of retinoid X receptor alpha is decreased in 3'-methyl-4-dimethylaminoazobenzene-induced hepatocellular carcinoma in rats. Ando N, etal., Oncol Rep. 2007 Oct;18(4):879-84.
2. Retinoid X receptor alpha participation in dexamethasone-induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver. Chen BC, etal., Shock. 2009 Aug;32(2):164-71.
3. Hydrodynamic-based in vivo transfection of retinoic X receptor-alpha gene can enhance vitamin A-induced attenuation of liver fibrosis in mice. Chen C, etal., Liver Int. 2004 Dec;24(6):679-86.
4. Role of retinoid-X receptor-alpha in the suppression of rat bile acid coenzyme A-amino acid N-acyltransferase in liver during sepsis. Chen YH, etal., Shock. 2007 Jul;28(1):65-70.
5. Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition. Dong YW, etal., World J Gastroenterol. 2009 Jan 28;15(4):441-8.
6. International Union of Pharmacology. LXIII. Retinoid X receptors. Germain P, etal., Pharmacol Rev. 2006 Dec;58(4):760-72.
7. Peroxisome proliferator-activated receptor-gamma and retinoid X receptor-alpha expression in pancreatic ductal adenocarcinoma: association with clinicopathological parameters, tumor proliferative capacity, and patients' survival. Giaginis C, etal., Med Sci Monit. 2009 May;15(5):BR148-56.
8. Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers. Grubbs CJ, etal., Carcinogenesis. 2006 Jun;27(6):1232-9. Epub 2005 Dec 12.
9. [Peroxisome proliferator-activated receptor alpha and retinoid X receptor alpha expressions and intervention in alcoholic cardiomyopathy rats] Jing L, etal., Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Apr;37(4):324-9.
10. Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. McGrane MM J Nutr Biochem. 2007 Aug;18(8):497-508. Epub 2007 Feb 22.
11. Functional role of RXRs and PPARgamma in mature adipocytes. Metzger D, etal., Prostaglandins Leukot Essent Fatty Acids. 2005 Jul;73(1):51-8.
12. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
13. MGDs mouse GO annotations MGD data from the GO Consortium
14. MGD IEA MGD IEA
15. Disturbance of retinol transportation causes nitrofen-induced hypoplastic lung. Nakazawa N, etal., J Pediatr Surg. 2007 Feb;42(2):345-9.
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium. Schlicht M, etal., BMC Genomics. 2004 Aug 20;5(1):58.
20. Regulation of retinoic acid receptors alpha, beta and retinoid X receptor alpha after sciatic nerve injury. Zhelyaznik N and Mey J, Neuroscience. 2006 Sep 15;141(4):1761-74. Epub 2006 Jun 19.
Additional References at PubMed
PMID:1310259   PMID:1312497   PMID:1358808   PMID:7638202   PMID:7744009   PMID:7760852   PMID:7774911   PMID:7823919   PMID:7831303   PMID:7838715   PMID:7923367   PMID:7926783  
PMID:7947324   PMID:7967725   PMID:7980510   PMID:7988794   PMID:8075499   PMID:8088777   PMID:8090775   PMID:8199055   PMID:8299717   PMID:8524212   PMID:8559662   PMID:8575300  
PMID:8597642   PMID:8598193   PMID:8604312   PMID:8631847   PMID:8780715   PMID:8786137   PMID:8799145   PMID:8799160   PMID:8801169   PMID:8801176   PMID:8823298   PMID:8855277  
PMID:8901052   PMID:8910441   PMID:8954108   PMID:8961274   PMID:8978696   PMID:9000050   PMID:9022057   PMID:9053308   PMID:9075714   PMID:9153406   PMID:9241280   PMID:9348290  
PMID:9356169   PMID:9376317   PMID:9425147   PMID:9428411   PMID:9430642   PMID:9442090   PMID:9464546   PMID:9548551   PMID:9550726   PMID:9550727   PMID:9628876   PMID:9795230  
PMID:9804293   PMID:9806918   PMID:9892670   PMID:9933587   PMID:10049761   PMID:10079186   PMID:10094571   PMID:10349636   PMID:10385625   PMID:10406480   PMID:10452855   PMID:10490294  
PMID:10604193   PMID:10610030   PMID:10625552   PMID:10675365   PMID:10694476   PMID:10753524   PMID:10788465   PMID:10825207   PMID:10866995   PMID:10869350   PMID:10880050   PMID:10882070  
PMID:10919981   PMID:11034212   PMID:11042159   PMID:11053444   PMID:11076796   PMID:11076861   PMID:11134524   PMID:11171393   PMID:11208732   PMID:11217851   PMID:11259580   PMID:11287642  
PMID:11297512   PMID:11328745   PMID:11493527   PMID:11595821   PMID:11795391   PMID:11830573   PMID:11860472   PMID:11980850   PMID:12015306   PMID:12054477   PMID:12093741   PMID:12149478  
PMID:12183441   PMID:12204252   PMID:12297106   PMID:12360493   PMID:12446833   PMID:12466851   PMID:12477932   PMID:12505043   PMID:12533419   PMID:12535669   PMID:12538623   PMID:12581641  
PMID:12746291   PMID:12750559   PMID:12753917   PMID:12824162   PMID:12840167   PMID:12966085   PMID:14500356   PMID:14529153   PMID:14560013   PMID:14610273   PMID:14701856   PMID:14742273  
PMID:14967906   PMID:14978233   PMID:15096541   PMID:15103326   PMID:15150259   PMID:15282742   PMID:15319426   PMID:15322135   PMID:15340084   PMID:15528208   PMID:15542861   PMID:15572671  
PMID:15582777   PMID:15589691   PMID:15601766   PMID:15601870   PMID:15618518   PMID:15623424   PMID:15646024   PMID:15647825   PMID:15681609   PMID:15699354   PMID:15731112   PMID:15738621  
PMID:15766748   PMID:15782199   PMID:15861408   PMID:16043864   PMID:16128002   PMID:16141072   PMID:16141073   PMID:16156795   PMID:16157696   PMID:16179348   PMID:16199515   PMID:16259011  
PMID:16271724   PMID:16352730   PMID:16424021   PMID:16428452   PMID:16498401   PMID:16574820   PMID:16606617   PMID:16751185   PMID:16829625   PMID:16880407   PMID:16888087   PMID:16963076  
PMID:16971476   PMID:16973757   PMID:17008383   PMID:17018855   PMID:17074929   PMID:17107947   PMID:17124491   PMID:17195188   PMID:17270348   PMID:17301838   PMID:17433077   PMID:17521607  
PMID:17595322   PMID:17613434   PMID:17641689   PMID:17656367   PMID:17823970   PMID:17951580   PMID:17952069   PMID:18028902   PMID:18196602   PMID:18270576   PMID:18282814   PMID:18287559  
PMID:18393306   PMID:18408763   PMID:18561907   PMID:18675890   PMID:18713813   PMID:18755030   PMID:18773928   PMID:18784308   PMID:18952117   PMID:19121312   PMID:19167885   PMID:19176532  
PMID:19188585   PMID:19255444   PMID:19300518   PMID:19345331   PMID:19414603   PMID:19448158   PMID:19605690   PMID:19665987   PMID:19686701   PMID:19737349   PMID:19741146   PMID:19883617  
PMID:19897601   PMID:20035057   PMID:20059953   PMID:20171278   PMID:20211142   PMID:20230754   PMID:20299672   PMID:20375256   PMID:20412781   PMID:20498053   PMID:20557428   PMID:20629968  
PMID:20685850   PMID:20798333   PMID:20932939   PMID:20944655   PMID:21060791   PMID:21135166   PMID:21138976   PMID:21152046   PMID:21267068   PMID:21343363   PMID:21349840   PMID:21525287  
PMID:21658367   PMID:21873635   PMID:21940995   PMID:22001906   PMID:22040871   PMID:22098603   PMID:22138104   PMID:22314496   PMID:22316320   PMID:22573555   PMID:22581777   PMID:22730183  
PMID:22982455   PMID:22988430   PMID:23166811   PMID:23342106   PMID:23499423   PMID:23585425   PMID:23602807   PMID:23775127   PMID:23896434   PMID:23977068   PMID:23981290   PMID:23990020  
PMID:24034621   PMID:24051096   PMID:24120911   PMID:24146318   PMID:24265455   PMID:24610012   PMID:24788806   PMID:24810760   PMID:24952961   PMID:24972164   PMID:25189354   PMID:25218146  
PMID:25324544   PMID:25417649   PMID:25451687   PMID:25574839   PMID:25577283   PMID:25738607   PMID:26221073   PMID:26241474   PMID:26410627   PMID:26427057   PMID:26443578   PMID:27051978  
PMID:27184385   PMID:27214556   PMID:27445154   PMID:27728806   PMID:27875243   PMID:28087565   PMID:28114934   PMID:28115699   PMID:28205585   PMID:28291835   PMID:28627642   PMID:28895119  
PMID:28923935   PMID:29031500   PMID:29044125   PMID:29089448   PMID:29093497   PMID:29121869   PMID:29431742   PMID:30146317   PMID:30355624   PMID:30931933   PMID:31006513   PMID:31152145  
PMID:31914884   PMID:32202512   PMID:32246014   PMID:32325033   PMID:32433958   PMID:32555436   PMID:33335079   PMID:33361153   PMID:33422545   PMID:33647291   PMID:34134472   PMID:34292881  
PMID:34599305   PMID:36028102   PMID:36282921   PMID:36484839   PMID:36889314   PMID:37141859   PMID:37225978   PMID:37477694   PMID:38310046   PMID:38372090  


Genomics

Comparative Map Data
Rxra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,566,457 - 27,653,331 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl227,566,452 - 27,652,969 (+)EnsemblGRCm39 Ensembl
GRCm38227,676,445 - 27,763,319 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,676,440 - 27,762,957 (+)EnsemblGRCm38mm10GRCm38
MGSCv37227,532,721 - 27,618,839 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36227,499,210 - 27,585,328 (+)NCBIMGSCv36mm8
Celera227,439,778 - 27,465,824 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
RXRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389134,326,455 - 134,440,585 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9134,317,098 - 134,440,585 (+)EnsemblGRCh38hg38GRCh38
GRCh379137,218,301 - 137,332,431 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369136,358,231 - 136,472,252 (+)NCBINCBI36Build 36hg18NCBI36
Build 349134,519,421 - 134,558,376NCBI
Celera9107,734,128 - 107,848,213 (+)NCBICelera
Cytogenetic Map9q34.2NCBI
HuRef9106,757,493 - 106,796,351 (+)NCBIHuRef
CHM1_19137,442,044 - 137,480,968 (+)NCBICHM1_1
T2T-CHM13v2.09146,541,633 - 146,657,063 (+)NCBIT2T-CHM13v2.0
Rxra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8331,387,892 - 31,474,415 (+)NCBIGRCr8
mRatBN7.2310,989,832 - 11,076,366 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,989,832 - 11,073,712 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx314,057,333 - 14,141,119 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0322,642,768 - 22,726,554 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0320,896,722 - 20,980,500 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.036,272,560 - 6,295,354 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,211,789 - 6,295,908 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0311,631,209 - 11,653,959 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,605,782 - 6,689,224 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.136,606,054 - 6,690,078 (+)NCBI
Celera35,843,675 - 5,866,536 (+)NCBICelera
Cytogenetic Map3p12NCBI
Rxra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555133,335,897 - 3,386,994 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555133,313,544 - 3,386,544 (+)NCBIChiLan1.0ChiLan1.0
RXRA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2114,937,570 - 5,052,654 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan194,939,903 - 5,054,985 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09105,424,046 - 105,539,241 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19134,082,865 - 134,144,704 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9134,082,865 - 134,144,704 (+)Ensemblpanpan1.1panPan2
RXRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1950,525,195 - 50,575,720 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl950,484,567 - 50,573,119 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha949,766,609 - 49,860,130 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0951,360,100 - 51,453,773 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl951,359,634 - 51,453,363 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1950,120,766 - 50,214,385 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0950,464,001 - 50,557,538 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0950,541,613 - 50,635,257 (+)NCBIUU_Cfam_GSD_1.0
Rxra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947200,612,017 - 200,639,947 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366692,738,448 - 2,763,070 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366692,735,111 - 2,763,060 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RXRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1273,705,505 - 273,797,620 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11273,698,842 - 273,797,622 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RXRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1123,704,129 - 3,814,707 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl123,699,923 - 3,814,678 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660581,284,770 - 1,401,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rxra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247602,380,708 - 2,456,928 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247602,379,809 - 2,455,749 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rxra
2896 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2910
Count of miRNA genes:713
Interacting mature miRNAs:920
Transcripts:ENSMUST00000077257, ENSMUST00000100251, ENSMUST00000113934, ENSMUST00000129514, ENSMUST00000148756, ENSMUST00000166775
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323494028179150Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse

Markers in Region
Rxra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
cM Map217.0UniSTS
cM Map217.0UniSTS
D2Mit120  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38227,712,048 - 27,712,193UniSTSGRCm38
MGSCv37227,567,568 - 27,567,713UniSTSGRCm37
Cytogenetic Map2A3UniSTS
cM Map217.0UniSTS
Whitehead Genetic221.9UniSTS
Whitehead/MRC_RH2492.61UniSTS
Whitehead_YAC2 UniSTS
Rxra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
Rxra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
Rxra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
Rxra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
cM Map217.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001290481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI647710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M84817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U77683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U77684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000077257   ⟹   ENSMUSP00000076491
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,567,213 - 27,652,969 (+)Ensembl
GRCm38.p6 Ensembl227,677,201 - 27,762,957 (+)Ensembl
Ensembl Acc Id: ENSMUST00000100251   ⟹   ENSMUSP00000097822
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,599,304 - 27,650,195 (+)Ensembl
GRCm38.p6 Ensembl227,709,292 - 27,760,183 (+)Ensembl
Ensembl Acc Id: ENSMUST00000113934   ⟹   ENSMUSP00000109567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,600,595 - 27,650,195 (+)Ensembl
GRCm38.p6 Ensembl227,710,583 - 27,760,183 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129514   ⟹   ENSMUSP00000115165
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,566,452 - 27,631,910 (+)Ensembl
GRCm38.p6 Ensembl227,676,440 - 27,741,898 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148756
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,630,213 - 27,638,683 (+)Ensembl
GRCm38.p6 Ensembl227,740,201 - 27,748,671 (+)Ensembl
Ensembl Acc Id: ENSMUST00000166775   ⟹   ENSMUSP00000133044
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,567,274 - 27,651,429 (+)Ensembl
GRCm38.p6 Ensembl227,677,262 - 27,761,417 (+)Ensembl
Ensembl Acc Id: ENSMUST00000238859   ⟹   ENSMUSP00000158864
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,611,163 - 27,644,360 (+)Ensembl
GRCm38.p6 Ensembl227,721,151 - 27,754,348 (+)Ensembl
Ensembl Acc Id: ENSMUST00000238913   ⟹   ENSMUSP00000159198
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl227,615,231 - 27,649,700 (+)Ensembl
GRCm38.p6 Ensembl227,725,219 - 27,759,688 (+)Ensembl
RefSeq Acc Id: NM_001290481   ⟹   NP_001277410
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39227,599,304 - 27,653,331 (+)NCBI
GRCm38227,709,292 - 27,763,319 (+)NCBI
Celera227,439,800 - 27,465,824 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001290482   ⟹   NP_001277411
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39227,600,595 - 27,653,331 (+)NCBI
GRCm38227,710,583 - 27,763,319 (+)NCBI
Celera227,439,800 - 27,465,824 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011305   ⟹   NP_035435
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39227,567,213 - 27,653,331 (+)NCBI
GRCm38227,677,201 - 27,763,319 (+)NCBI
MGSCv37227,532,721 - 27,618,839 (+)RGD
Celera227,439,800 - 27,465,824 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497805   ⟹   XP_006497868
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39227,566,457 - 27,652,969 (+)NCBI
GRCm38227,676,445 - 27,762,959 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248867   ⟹   XP_030104727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39227,625,166 - 27,652,969 (+)NCBI
GRCm38227,735,154 - 27,762,959 (+)NCBI
Sequence:
RefSeq Acc Id: NP_035435   ⟸   NM_011305
- Peptide Label: isoform 1
- UniProtKB: P28700 (UniProtKB/Swiss-Prot),   A2AJP1 (UniProtKB/TrEMBL),   Q3UMU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006497868   ⟸   XM_006497805
- Peptide Label: isoform X1
- UniProtKB: Q6LC96 (UniProtKB/TrEMBL),   Q3UMU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277411   ⟸   NM_001290482
- Peptide Label: isoform 2
- UniProtKB: Q6LC96 (UniProtKB/TrEMBL),   Q3UMU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277410   ⟸   NM_001290481
- Peptide Label: isoform 2
- UniProtKB: Q6LC96 (UniProtKB/TrEMBL),   Q3UMU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030104727   ⟸   XM_030248867
- Peptide Label: isoform X1
- UniProtKB: Q6LC96 (UniProtKB/TrEMBL),   Q3UMU4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000109567   ⟸   ENSMUST00000113934
Ensembl Acc Id: ENSMUSP00000133044   ⟸   ENSMUST00000166775
Ensembl Acc Id: ENSMUSP00000158864   ⟸   ENSMUST00000238859
Ensembl Acc Id: ENSMUSP00000159198   ⟸   ENSMUST00000238913
Ensembl Acc Id: ENSMUSP00000115165   ⟸   ENSMUST00000129514
Ensembl Acc Id: ENSMUSP00000097822   ⟸   ENSMUST00000100251
Ensembl Acc Id: ENSMUSP00000076491   ⟸   ENSMUST00000077257
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28700-F1-model_v2 AlphaFold P28700 1-467 view protein structure

Promoters
RGD ID:6832635
Promoter ID:MM_KWN:28368
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4
Transcripts:OTTMUST00000028668
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36227,531,214 - 27,531,714 (+)MPROMDB
RGD ID:6832634
Promoter ID:MM_KWN:28369
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_011305
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36227,531,756 - 27,533,052 (+)MPROMDB
RGD ID:6832632
Promoter ID:MM_KWN:28370
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day4,   Liver
Transcripts:ENSMUST00000100251
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36227,564,466 - 27,564,966 (+)MPROMDB
RGD ID:6832633
Promoter ID:MM_KWN:28371
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000113934
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36227,565,371 - 27,566,602 (+)MPROMDB
RGD ID:6832637
Promoter ID:MM_KWN:28372
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B6
Transcripts:OTTMUST00000028669
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36227,594,731 - 27,596,107 (+)MPROMDB
RGD ID:6876770
Promoter ID:EPDNEW_M1836
Type:initiation region
Name:Rxra_1
Description:Mus musculus retinoid X receptor alpha , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1837  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38227,677,261 - 27,677,321EPDNEW
RGD ID:6876772
Promoter ID:EPDNEW_M1837
Type:multiple initiation site
Name:Rxra_2
Description:Mus musculus retinoid X receptor alpha , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1836  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38227,728,853 - 27,728,913EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98214 AgrOrtholog
Ensembl Genes ENSMUSG00000015846 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000077257 ENTREZGENE
  ENSMUST00000077257.12 UniProtKB/Swiss-Prot
  ENSMUST00000100251 ENTREZGENE
  ENSMUST00000100251.9 UniProtKB/TrEMBL
  ENSMUST00000113934 ENTREZGENE
  ENSMUST00000113934.2 UniProtKB/TrEMBL
  ENSMUST00000129514.8 UniProtKB/TrEMBL
  ENSMUST00000238859.2 UniProtKB/TrEMBL
  ENSMUST00000238913