Ptprc (protein tyrosine phosphatase, receptor type, C) - Rat Genome Database

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Gene: Ptprc (protein tyrosine phosphatase, receptor type, C) Mus musculus
Analyze
Symbol: Ptprc
Name: protein tyrosine phosphatase, receptor type, C
RGD ID: 11196
MGI Page MGI
Description: Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of immune response; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including T cell activation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; cardiovascular system; hemolymphoid system; placenta; and skin. Used to study Alzheimer's disease and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in multiple sclerosis; primary immunodeficiency disease; and severe combined immunodeficiency. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B220; Cd45; CD45R; L-CA; leukocyte common antigen; loc; Ly-; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-; Lyt-4; receptor-type tyrosine-protein phosphatase C; T200
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391137,990,597 - 138,103,491 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1137,990,599 - 138,103,446 (-)EnsemblGRCm39 Ensembl
GRCm381138,062,859 - 138,175,756 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1138,062,861 - 138,175,708 (-)EnsemblGRCm38mm10GRCm38
MGSCv371139,959,438 - 140,071,882 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361139,879,826 - 139,991,677 (-)NCBIMGSCv36mm8
Celera1140,702,480 - 140,816,534 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map160.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-acetamidofluorene  (ISO)
2-butoxyethanol  (EXP)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allyl methyl disulfide  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
beauvericin  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
Calcimycin  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroprene  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
Cuprizon  (ISO)
cyclophosphamide  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (EXP,ISO)
diclofenac  (EXP)
diethylstilbestrol  (EXP)
dimethylarsinic acid  (EXP)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
enniatin  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
folpet  (EXP)
formaldehyde  (ISO)
furan  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glycidol  (ISO)
histamine  (ISO)
isotretinoin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (EXP)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nitrofen  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
pirinixic acid  (EXP,ISO)
silicon dioxide  (EXP,ISO)
sirolimus  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (EXP)
Soman  (ISO)
succimer  (EXP)
T-2 toxin  (ISO)
tamibarotene  (ISO)
tebuconazole  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
Tributyltin oxide  (EXP)
triprolidine  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
tungsten  (EXP)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alpha-beta T cell proliferation  (IMP)
B cell differentiation  (IMP)
B cell proliferation  (IMP)
B cell receptor signaling pathway  (IMP)
bone marrow development  (ISO)
calcium-mediated signaling using intracellular calcium source  (IGI)
cell cycle phase transition  (ISO)
cellular response to extracellular stimulus  (IGI)
defense response to virus  (IDA,IMP)
dephosphorylation  (IDA)
extrinsic apoptotic signaling pathway  (IMP)
gamma-delta T cell differentiation  (IMP)
hematopoietic progenitor cell differentiation  (ISO)
heterotypic cell-cell adhesion  (IMP)
leukocyte cell-cell adhesion  (IMP)
MAPK cascade  (IMP)
natural killer cell differentiation  (IMP)
negative regulation of cell adhesion involved in substrate-bound cell migration  (ISO)
negative regulation of cytokine-mediated signaling pathway  (IDA)
negative regulation of ERK1 and ERK2 cascade  (IGI)
negative regulation of interleukin-2 production  (IGI)
negative regulation of peptidyl-tyrosine phosphorylation  (IMP)
negative regulation of protein autophosphorylation  (IMP)
negative regulation of protein kinase activity  (IBA,IDA,ISO)
negative regulation of protein tyrosine kinase activity  (IGI)
negative regulation of T cell mediated cytotoxicity  (IMP)
negative thymic T cell selection  (IMP)
peptidyl-tyrosine phosphorylation  (IMP)
plasma membrane raft distribution  (IGI)
positive regulation of alpha-beta T cell proliferation  (IMP)
positive regulation of antigen receptor-mediated signaling pathway  (IMP)
positive regulation of B cell proliferation  (IMP,ISO)
positive regulation of ERK1 and ERK2 cascade  (IGI)
positive regulation of extrinsic apoptotic signaling pathway  (IMP)
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis  (IGI)
positive regulation of gamma-delta T cell differentiation  (IMP)
positive regulation of hematopoietic stem cell migration  (ISO)
positive regulation of humoral immune response mediated by circulating immunoglobulin  (IMP)
positive regulation of immunoglobulin production  (ISO)
positive regulation of interleukin-2 production  (IGI)
positive regulation of isotype switching to IgG isotypes  (IMP)
positive regulation of MAP kinase activity  (IMP)
positive regulation of MAPK cascade  (IGI,IMP)
positive regulation of peptidyl-tyrosine phosphorylation  (IBA,IGI)
positive regulation of protein tyrosine phosphatase activity  (IGI)
positive regulation of stem cell proliferation  (ISO)
positive regulation of T cell differentiation  (IMP)
positive regulation of T cell mediated cytotoxicity  (IMP)
positive regulation of T cell mediated immunity  (IMP)
positive regulation of T cell proliferation  (IMP)
positive regulation of tumor necrosis factor production  (IGI)
positive thymic T cell selection  (IMP)
protein autophosphorylation  (IMP)
protein dephosphorylation  (IBA,IDA)
regulation of cell cycle  (IDA)
regulation of extrinsic apoptotic signaling pathway  (IMP)
regulation of gene expression  (IGI,ISO)
regulation of humoral immune response mediated by circulating immunoglobulin  (IMP)
regulation of interleukin-8 production  (ISO)
regulation of phagocytosis  (ISO)
regulation of protein tyrosine kinase activity  (ISO)
regulation of receptor signaling pathway via JAK-STAT  (ISO)
release of sequestered calcium ion into cytosol  (IDA)
response to gamma radiation  (ISO)
stem cell development  (ISO)
T cell differentiation  (IMP)
T cell proliferation  (IMP)
T cell receptor signaling pathway  (IGI,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell activation  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal B cell number  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal CD4-positive T cell differentiation  (IAGP)
abnormal CD4-positive, alpha-beta intraepithelial T cell morphology  (IAGP)
abnormal CD8-positive, alpha beta T cell morphology  (IEA)
abnormal CD8-positive, alpha-beta T cell differentiation  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal digestion  (IAGP)
abnormal double-positive T cell morphology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal follicular B cell morphology  (IAGP)
abnormal follicular B cell physiology  (IAGP)
abnormal granulocyte differentiation  (IAGP)
abnormal humoral immune response  (IEA)
abnormal immune system cell morphology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal interferon level  (IAGP)
abnormal intraepithelial T cell morphology  (IAGP)
abnormal intraepithelial T cell number  (IAGP)
abnormal leukocyte cell number  (IAGP)
abnormal leukocyte morphology  (IEA)
abnormal long bone metaphysis morphology  (IAGP)
abnormal lymphocyte cell number  (IAGP)
abnormal lymphocyte morphology  (IEA)
abnormal lymphopoiesis  (IAGP)
abnormal memory T cell number  (IEA)
abnormal myelination  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal NK cell physiology  (IAGP)
abnormal oligodendrocyte morphology  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal osteoclast physiology  (IAGP)
abnormal positive T cell selection  (IAGP)
abnormal response to infection  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal susceptibility to infection induced morbidity/mortality  (IAGP)
abnormal T cell activation  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell morphology  (IEA)
abnormal T cell physiology  (IAGP)
abnormal T cell selection  (IEA)
abnormal T cell subpopulation ratio  (IAGP)
abnormal thymocyte activation  (IAGP)
abnormal transitional stage B cell morphology  (IAGP)
absent T cells  (IEA)
anemia  (IAGP)
arrested T cell differentiation  (IAGP)
CNS inflammation  (IAGP)
decreased alpha-beta T cell number  (IEA)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased B-1a cell number  (IEA)
decreased B-1b cell number  (IEA)
decreased B-2 B cell number  (IEA)
decreased body weight  (IAGP)
decreased CD4-positive, alpha-beta memory T cell number  (IEA)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta memory T cell number  (IEA)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, naive alpha-beta T cell number  (IEA)
decreased central memory CD8 positive, alpha-beta T cell number  (IEA)
decreased cytotoxic T cell cytolysis  (IAGP)
decreased DN4 thymocyte number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased effector memory CD4-positive, alpha-beta T cell number  (IEA)
decreased follicular B cell number  (IAGP)
decreased gamma-delta intraepithelial T cell number  (IAGP)
decreased IgE level  (IEA)
decreased immature B cell number  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased mast cell degranulation  (IAGP)
decreased mature B cell number  (IAGP)
decreased memory B cell number  (IEA)
decreased memory T cell number  (IEA)
decreased NK cell number  (IEA)
decreased NK T cell number  (IEA)
decreased oligodendrocyte number  (IAGP)
decreased single-positive T cell number  (IEA)
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality  (IAGP)
decreased susceptibility to type I hypersensitivity reaction  (IAGP)
decreased systemic arterial systolic blood pressure  (IEA)
decreased T cell number  (IAGP)
decreased T cell proliferation  (IAGP)
decreased thymocyte number  (IAGP)
diarrhea  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
glomerulonephritis  (IAGP)
glomerulosclerosis  (IAGP)
impaired macrophage phagocytosis  (IAGP)
increased alpha-beta T cell number  (IEA)
increased anti-double stranded DNA antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell number  (IAGP)
increased B-1 B cell number  (IEA)
increased B-1b cell number  (IEA)
increased CD8-positive, alpha-beta T cell number  (IEA)
increased central memory CD4-positive, alpha-beta T cell number  (IEA)
increased central memory CD8 positive, alpha-beta T cell number  (IEA)
increased dendritic cell number  (IEA)
increased DN3 thymocyte number  (IAGP)
increased double-negative T cell number  (IAGP)
increased effector memory CD4-positive, alpha-beta T cell number  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased IgA level  (IAGP)
increased IgG2a level  (IAGP)
increased memory T cell number  (IAGP)
increased neutrophil cell number  (IEA)
increased NK cell number  (IAGP)
increased plasma cell number  (IAGP)
increased plasmacytoid dendritic cell number  (IAGP)
increased single-positive T cell number  (IEA)
increased spleen red pulp amount  (IAGP)
increased spleen white pulp amount  (IAGP)
increased susceptibility to autoimmune disorder  (IAGP)
increased susceptibility to Herpesvirales infection  (IAGP)
increased susceptibility to Herpesvirales infection induced morbidity/mortality  (IAGP)
increased T cell apoptosis  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased T cell number  (IAGP)
increased transitional stage B cell number  (IAGP)
increased urine protein level  (IAGP)
kidney failure  (IAGP)
lethality at weaning, incomplete penetrance  (IAGP)
liver inflammation  (IAGP)
lung inflammation  (IAGP)
lymph node hyperplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
oliguria  (IAGP)
pale kidney  (IAGP)
premature death  (IAGP)
spleen hyperplasia  (IAGP)
thymus hyperplasia  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A point mutation in PTPRC is associated with the development of multiple sclerosis. Jacobsen M, etal., Nat Genet 2000 Dec;26(4):495-9.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. A deletion in the gene encoding the CD45 antigen in a patient with SCID. Tchilian EZ, etal., J Immunol. 2001 Jan 15;166(2):1308-13.
11. Administration of recombinant P-selectin glycoprotein ligand Fc fusion protein suppresses inflammation and neointimal formation in Zucker diabetic rat model. Zhou Z, etal., Arterioscler Thromb Vasc Biol 2002 Oct 1;22(10):1598-603.
Additional References at PubMed
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PMID:8046327   PMID:8101401   PMID:8175795   PMID:8182339   PMID:8288230   PMID:8334701   PMID:8452817   PMID:8551241   PMID:8552190   PMID:8566025   PMID:8566034   PMID:8570203  
PMID:8632004   PMID:8661716   PMID:8666928   PMID:8692271   PMID:8747926   PMID:8747928   PMID:8759740   PMID:8788039   PMID:8875997   PMID:8903730   PMID:8954783   PMID:9015183  
PMID:9064344   PMID:9107685   PMID:9120275   PMID:9148925   PMID:9190928   PMID:9197241   PMID:9208839   PMID:9254656   PMID:9285409   PMID:9324357   PMID:9376320   PMID:9581568  
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PMID:10358768   PMID:10397738   PMID:10403645   PMID:10429672   PMID:10458749   PMID:10508267   PMID:10556550   PMID:10575213   PMID:10631184   PMID:10648121   PMID:10749569   PMID:10770800  
PMID:10829061   PMID:10848813   PMID:10906147   PMID:10926756   PMID:10943840   PMID:10943842   PMID:10970857   PMID:11042159   PMID:11076861   PMID:11093154   PMID:11163182   PMID:11201744  
PMID:11217851   PMID:11260323   PMID:11342624   PMID:11466198   PMID:11476574   PMID:11544199   PMID:11698303   PMID:11716526   PMID:11884039   PMID:11994430   PMID:12004082   PMID:12022705  
PMID:12049718   PMID:12055218   PMID:12068292   PMID:12091326   PMID:12115612   PMID:12207342   PMID:12209639   PMID:12244310   PMID:12244311   PMID:12376545   PMID:12391219   PMID:12391333  
PMID:12393487   PMID:12414501   PMID:12466851   PMID:12477932   PMID:12496963   PMID:12499376   PMID:12612075   PMID:12648490   PMID:12714519   PMID:12731066   PMID:12805065   PMID:12900455  
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PMID:15723811   PMID:15778367   PMID:15790953   PMID:15795238   PMID:15823427   PMID:15843532   PMID:15845452   PMID:15845899   PMID:15857912   PMID:15867094   PMID:15909309   PMID:16020514  
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PMID:18594778   PMID:18602924   PMID:18627106   PMID:18628982   PMID:18653563   PMID:18684862   PMID:18725519   PMID:18762567   PMID:18769712   PMID:18779349   PMID:18922161   PMID:18941197  
PMID:18952892   PMID:18981123   PMID:19001138   PMID:19008920   PMID:19015308   PMID:19060331   PMID:19129486   PMID:19135046   PMID:19164539   PMID:19164599   PMID:19234195   PMID:19246339  
PMID:19269962   PMID:19299707   PMID:19332117   PMID:19380791   PMID:19428458   PMID:19478957   PMID:19571816   PMID:19683682   PMID:19727123   PMID:19728314   PMID:19765855   PMID:19783990  
PMID:19838199   PMID:19841086   PMID:19861679   PMID:19875815   PMID:19901263   PMID:19920154   PMID:19934022   PMID:19995948   PMID:20043899   PMID:20130220   PMID:20208005   PMID:20346773  
PMID:20382704   PMID:20505149   PMID:20606166   PMID:20624943   PMID:20625006   PMID:20660734   PMID:20679227   PMID:20709950   PMID:20802149   PMID:20805985   PMID:20856869   PMID:20876651  
PMID:20890286   PMID:20978081   PMID:20980401   PMID:21098236   PMID:21108466   PMID:21173243   PMID:21181199   PMID:21245479   PMID:21267068   PMID:21273420   PMID:21282629   PMID:21300983  
PMID:21308776   PMID:21355089   PMID:21423172   PMID:21460847   PMID:21464233   PMID:21469133   PMID:21502490   PMID:21502514   PMID:21515254   PMID:21572048   PMID:21606356   PMID:21613258  
PMID:21633705   PMID:21636294   PMID:21705651   PMID:21788582   PMID:21816924   PMID:21825019   PMID:21873635   PMID:21883169   PMID:21911094   PMID:21990046   PMID:22018468   PMID:22033010  
PMID:22046273   PMID:22048769   PMID:22072979   PMID:22078799   PMID:22135465   PMID:22144566   PMID:22194995   PMID:22354871   PMID:22354913   PMID:22387002   PMID:22387552   PMID:22406641  
PMID:22415881   PMID:22425250   PMID:22442384   PMID:22464328   PMID:22496360   PMID:22504651   PMID:22538191   PMID:22552287   PMID:22558218   PMID:22563733   PMID:22670056   PMID:22677420  
PMID:22682244   PMID:22724066   PMID:22726954   PMID:22727490   PMID:22753134   PMID:22786774   PMID:22837485   PMID:22848581   PMID:22902503   PMID:22988576   PMID:23018460   PMID:23029475  
PMID:23092738   PMID:23151848   PMID:23233664   PMID:23248263   PMID:23281368   PMID:23315077   PMID:23315977   PMID:23319349   PMID:23334579   PMID:23362346   PMID:23396948   PMID:23454348  
PMID:23454691   PMID:23530149   PMID:23536629   PMID:23554311   PMID:23563688   PMID:23580664   PMID:23585679   PMID:23601687   PMID:23624556   PMID:23636055   PMID:23636062   PMID:23644514  
PMID:23675296   PMID:23676498   PMID:23744647   PMID:23750244   PMID:23762028   PMID:23812589   PMID:23812634   PMID:23878314   PMID:23883515   PMID:23904165   PMID:23913971   PMID:23928494  
PMID:23936270   PMID:23997015   PMID:24029230   PMID:24068938   PMID:24123684   PMID:24129162   PMID:24141946   PMID:24143212   PMID:24255917   PMID:24336287   PMID:24478402   PMID:24515435  
PMID:24551160   PMID:24569637   PMID:24620029   PMID:24639353   PMID:24670648   PMID:24681564   PMID:24745333   PMID:24757004   PMID:24805242   PMID:24821911   PMID:24852660   PMID:24912173  
PMID:24952961   PMID:24958848   PMID:24990886   PMID:25074919   PMID:25075129   PMID:25114101   PMID:25139854   PMID:25144937   PMID:25202978   PMID:25228759   PMID:25241746   PMID:25267612  
PMID:25312647   PMID:25326802   PMID:25378482   PMID:25393502   PMID:25415437   PMID:25425146   PMID:25502838   PMID:25505282   PMID:25523391   PMID:25526309   PMID:25715394   PMID:25727904  
PMID:25740827   PMID:25769918   PMID:25772358   PMID:25838284   PMID:25939026   PMID:25953241   PMID:25963626   PMID:26011640   PMID:26011644   PMID:26077719   PMID:26105028   PMID:26109379  
PMID:26204127   PMID:26370500   PMID:26373280   PMID:26417101   PMID:26426795   PMID:26458765   PMID:26488883   PMID:26561584   PMID:26642357   PMID:26655331   PMID:26657143   PMID:26671981  
PMID:26743624   PMID:26773036   PMID:26801976   PMID:26834239   PMID:26935419   PMID:26952187   PMID:26974206   PMID:27007678   PMID:27125672   PMID:27128622   PMID:27135602   PMID:27160938  
PMID:27185283   PMID:27227884   PMID:27295349   PMID:27357698   PMID:27386825   PMID:27531557   PMID:27579617   PMID:27623309   PMID:27680685   PMID:27694385   PMID:27729526   PMID:27732840  
PMID:27732841   PMID:27841348   PMID:27880917   PMID:27895423   PMID:28025077   PMID:28100745   PMID:28108297   PMID:28111199   PMID:28218908   PMID:28346423   PMID:28352167   PMID:28363897  
PMID:28378742   PMID:28402856   PMID:28592560   PMID:28605013   PMID:28634350   PMID:28644433   PMID:28709801   PMID:28735895   PMID:28742882   PMID:28809397   PMID:28819138   PMID:28891216  
PMID:28964716   PMID:29114040   PMID:29176738   PMID:29259102   PMID:29323295   PMID:29440507   PMID:29507409   PMID:29555821   PMID:29562201   PMID:29665133   PMID:29768210   PMID:29773646  
PMID:29798841   PMID:29853539   PMID:29946151   PMID:29980684   PMID:29996101   PMID:30068597   PMID:30143634   PMID:30185824   PMID:30187863   PMID:30196744   PMID:30356064   PMID:30514882  
PMID:30538245   PMID:30540940   PMID:30550785   PMID:30573502   PMID:30733279   PMID:30737373   PMID:30799229   PMID:30820040   PMID:30884041   PMID:30923168   PMID:30929925   PMID:30988302  
PMID:31024525   PMID:31086209   PMID:31167773   PMID:31201093   PMID:31226719   PMID:31269437   PMID:31323030   PMID:31519887   PMID:31552487   PMID:31641081   PMID:31673770   PMID:31729371  
PMID:31801072   PMID:31924792   PMID:31980640   PMID:32005855   PMID:32294445   PMID:32294451   PMID:32296175   PMID:32369449   PMID:32423405   PMID:32450207   PMID:32457985   PMID:32467237  
PMID:32553121   PMID:32553167   PMID:32554809   PMID:32561755   PMID:32610127   PMID:32878924   PMID:32978280   PMID:33037075   PMID:33042133   PMID:33086067   PMID:33130914   PMID:33331104  
PMID:33357430   PMID:33454424   PMID:33542915   PMID:33590845   PMID:33674596   PMID:33707780   PMID:33710665   PMID:33767712   PMID:33887203   PMID:33990399   PMID:34001904   PMID:34007995  
PMID:34117110   PMID:34162836   PMID:34233187   PMID:34260913   PMID:34380042   PMID:34446743   PMID:34461100   PMID:34497346   PMID:34533228   PMID:34559199   PMID:34589491   PMID:34877502  
PMID:34996942   PMID:35042581   PMID:35069539   PMID:35230871   PMID:35293576   PMID:35358427   PMID:35482005   PMID:35541897   PMID:35599984   PMID:35614226   PMID:35829816   PMID:35998585  
PMID:36277751   PMID:36414671   PMID:36441774   PMID:36450771   PMID:36473461   PMID:36638795   PMID:36656933  


Genomics

Comparative Map Data
Ptprc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391137,990,597 - 138,103,491 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1137,990,599 - 138,103,446 (-)EnsemblGRCm39 Ensembl
GRCm381138,062,859 - 138,175,756 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1138,062,861 - 138,175,708 (-)EnsemblGRCm38mm10GRCm38
MGSCv371139,959,438 - 140,071,882 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361139,879,826 - 139,991,677 (-)NCBIMGSCv36mm8
Celera1140,702,480 - 140,816,534 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map160.73NCBI
PTPRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381198,638,713 - 198,757,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1198,638,457 - 198,757,476 (+)EnsemblGRCh38hg38GRCh38
GRCh371198,608,170 - 198,726,605 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361196,874,760 - 196,993,168 (+)NCBINCBI36Build 36hg18NCBI36
Build 341195,339,881 - 195,393,989NCBI
Celera1171,730,687 - 171,849,073 (+)NCBICelera
Cytogenetic Map1q31.3-q32.1NCBI
HuRef1169,775,326 - 169,893,838 (+)NCBIHuRef
CHM1_11200,030,413 - 200,148,903 (+)NCBICHM1_1
T2T-CHM13v2.01197,898,964 - 198,017,392 (+)NCBIT2T-CHM13v2.0
Ptprc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21349,596,193 - 49,708,283 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1349,596,193 - 49,708,692 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1352,203,850 - 52,315,661 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01353,491,734 - 53,603,549 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01350,758,824 - 50,870,643 (-)NCBIRnor_WKY
Rnor_6.01355,061,561 - 55,174,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1355,061,562 - 55,173,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01360,094,038 - 60,205,773 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41351,246,163 - 51,357,995 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11351,261,097 - 51,309,893 (-)NCBI
Celera1349,881,478 - 49,993,142 (-)NCBICelera
Cytogenetic Map13q13NCBI
Ptprc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540635,005,214 - 35,129,552 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540635,005,577 - 35,127,395 (+)NCBIChiLan1.0ChiLan1.0
PTPRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11178,555,803 - 178,674,089 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1178,556,104 - 178,672,994 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01174,246,389 - 174,364,893 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PTPRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.174,155,876 - 4,282,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl74,137,728 - 4,282,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha73,841,036 - 3,967,333 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.073,809,638 - 3,848,816 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.073,851,043 - 3,967,973 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl73,809,641 - 3,967,858 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.173,787,560 - 3,913,845 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.073,889,732 - 4,015,907 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.073,921,322 - 4,047,618 (-)NCBIUU_Cfam_GSD_1.0
Ptprc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934476,032,103 - 76,143,785 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365675,267,615 - 5,378,258 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365675,266,653 - 5,378,464 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1021,560,073 - 21,601,308 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11021,482,984 - 21,601,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21026,308,772 - 26,332,086 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12530,655,014 - 30,777,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2530,653,044 - 30,777,303 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605531,544,354 - 31,666,237 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247981,699,541 - 1,814,656 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247981,700,732 - 1,814,603 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1981
Count of miRNA genes:425
Interacting mature miRNAs:502
Transcripts:ENSMUST00000027645, ENSMUST00000112036, ENSMUST00000182138, ENSMUST00000182283, ENSMUST00000182536, ENSMUST00000182755, ENSMUST00000183229, ENSMUST00000183262, ENSMUST00000183301
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131156308165139464Mouse
14746980Manh50_mmandible shape 50 (mouse)1134131564168131564Mouse
13504831Bacszq1_mbaculum size QTL 1 (mouse)1134331161148128608Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135794822169795012Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1135877901169878015Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136209950170210094Mouse

Markers in Region
Ptprc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1E4UniSTS
cM Map174.0UniSTS
D1Mit514  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381138,064,218 - 138,064,333UniSTSGRCm38
MGSCv371139,960,795 - 139,960,910UniSTSGRCm37
Celera1140,703,837 - 140,703,952UniSTS
Cytogenetic Map1E4UniSTS
cM Map1 UniSTS
AU026553  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381138,075,376 - 138,075,946UniSTSGRCm38
MGSCv371139,971,953 - 139,972,523UniSTSGRCm37
Celera1140,714,995 - 140,715,565UniSTS
Cytogenetic Map1E4UniSTS
cM Map174.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001268286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH001989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH004969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC084684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM239381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX517622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA575153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA577897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK392851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS104362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF101553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L36091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M17320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M92933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000112036
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1137,990,599 - 138,044,179 (-)Ensembl
GRCm38.p6 Ensembl1138,062,861 - 138,116,441 (-)Ensembl
RefSeq Acc Id: ENSMUST00000182138
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,051,611 - 138,103,034 (-)Ensembl
GRCm38.p6 Ensembl1138,123,873 - 138,175,296 (-)Ensembl
RefSeq Acc Id: ENSMUST00000182283   ⟹   ENSMUSP00000138800
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1137,991,145 - 138,103,044 (-)Ensembl
GRCm38.p6 Ensembl1138,063,407 - 138,175,306 (-)Ensembl
RefSeq Acc Id: ENSMUST00000182755   ⟹   ENSMUSP00000138275
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1137,991,158 - 138,103,038 (-)Ensembl
GRCm38.p6 Ensembl1138,063,420 - 138,175,300 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183229
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,053,947 - 138,103,446 (-)Ensembl
GRCm38.p6 Ensembl1138,126,209 - 138,175,708 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183262
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,047,211 - 138,103,037 (-)Ensembl
GRCm38.p6 Ensembl1138,119,473 - 138,175,299 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183301   ⟹   ENSMUSP00000138350
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1137,991,151 - 138,103,005 (-)Ensembl
GRCm38.p6 Ensembl1138,063,413 - 138,175,267 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185570
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,099,715 - 138,102,927 (-)Ensembl
GRCm38.p6 Ensembl1138,171,977 - 138,175,189 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186628
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,100,482 - 138,102,987 (-)Ensembl
GRCm38.p6 Ensembl1138,172,744 - 138,175,249 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187586
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,045,075 - 138,048,458 (-)Ensembl
GRCm38.p6 Ensembl1138,117,337 - 138,120,720 (-)Ensembl
RefSeq Acc Id: ENSMUST00000188596
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,039,768 - 138,043,212 (-)Ensembl
GRCm38.p6 Ensembl1138,112,030 - 138,115,474 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193650   ⟹   ENSMUSP00000141524
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,045,576 - 138,103,038 (-)Ensembl
GRCm38.p6 Ensembl1138,117,838 - 138,175,300 (-)Ensembl
RefSeq Acc Id: ENSMUST00000195533   ⟹   ENSMUSP00000142052
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1138,039,990 - 138,102,972 (-)Ensembl
GRCm38.p6 Ensembl1138,112,252 - 138,175,234 (-)Ensembl
RefSeq Acc Id: NM_001111316   ⟹   NP_001104786
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,990,597 - 138,102,864 (-)NCBI
GRCm381138,062,859 - 138,175,126 (-)NCBI
MGSCv371139,959,438 - 140,071,882 (-)RGD
Celera1140,702,478 - 140,816,534 (-)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001268286   ⟹   NP_001255215
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,990,597 - 138,103,043 (-)NCBI
GRCm381138,062,859 - 138,175,305 (-)NCBI
Celera1140,702,478 - 140,816,534 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011210   ⟹   NP_035340
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,990,597 - 138,103,043 (-)NCBI
GRCm381138,062,859 - 138,175,305 (-)NCBI
MGSCv371139,959,438 - 140,071,882 (-)RGD
Celera1140,702,478 - 140,816,534 (-)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529257   ⟹   XP_006529320
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,991,145 - 138,103,057 (-)NCBI
GRCm381138,063,407 - 138,175,320 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529258   ⟹   XP_006529321
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,991,145 - 138,103,491 (-)NCBI
GRCm381138,063,407 - 138,175,756 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529259   ⟹   XP_006529322
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,991,145 - 138,103,070 (-)NCBI
GRCm381138,063,407 - 138,175,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529260   ⟹   XP_006529323
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,991,145 - 138,103,057 (-)NCBI
GRCm381138,063,407 - 138,175,319 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529261   ⟹   XP_006529324
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,991,145 - 138,103,057 (-)NCBI
GRCm381138,063,407 - 138,175,321 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529262   ⟹   XP_006529325
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391137,991,145 - 138,103,058 (-)NCBI
GRCm381138,063,407 - 138,175,321 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001104786 (Get FASTA)   NCBI Sequence Viewer  
  NP_001255215 (Get FASTA)   NCBI Sequence Viewer  
  NP_035340 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529320 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529321 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529322 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529323 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529324 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529325 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA39418 (Get FASTA)   NCBI Sequence Viewer  
  AAA39458 (Get FASTA)   NCBI Sequence Viewer  
  AAA39459 (Get FASTA)   NCBI Sequence Viewer  
  AAA39460 (Get FASTA)   NCBI Sequence Viewer  
  AAA39461 (Get FASTA)   NCBI Sequence Viewer  
  AAA39462 (Get FASTA)   NCBI Sequence Viewer  
  AAA40161 (Get FASTA)   NCBI Sequence Viewer  
  AAA60449 (Get FASTA)   NCBI Sequence Viewer  
  AAB46374 (Get FASTA)   NCBI Sequence Viewer  
  AAH28512 (Get FASTA)   NCBI Sequence Viewer  
  AAH84684 (Get FASTA)   NCBI Sequence Viewer  
  ABK96802 (Get FASTA)   NCBI Sequence Viewer  
  BAC35638 (Get FASTA)   NCBI Sequence Viewer  
  BAE32907 (Get FASTA)   NCBI Sequence Viewer  
  CAJ01231 (Get FASTA)   NCBI Sequence Viewer  
  EDL39541 (Get FASTA)   NCBI Sequence Viewer  
  EDL39542 (Get FASTA)   NCBI Sequence Viewer  
  P06800 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_035340   ⟸   NM_011210
- Peptide Label: isoform 2 precursor
- UniProtKB: Q8C6Q7 (UniProtKB/TrEMBL),   S4R2V1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104786   ⟸   NM_001111316
- Peptide Label: isoform 1 precursor
- UniProtKB: S4R2V1 (UniProtKB/Swiss-Prot),   Q8C6Q7 (UniProtKB/TrEMBL),   S4R1S4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001255215   ⟸   NM_001268286
- Peptide Label: precursor
- UniProtKB: Q8C6Q7 (UniProtKB/TrEMBL),   S4R1M0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529321   ⟸   XM_006529258
- Peptide Label: isoform X1
- UniProtKB: S4R2V1 (UniProtKB/Swiss-Prot),   S4R1S4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529322   ⟸   XM_006529259
- Peptide Label: isoform X1
- UniProtKB: S4R2V1 (UniProtKB/Swiss-Prot),   S4R1S4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529325   ⟸   XM_006529262
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006529323   ⟸   XM_006529260
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006529324   ⟸   XM_006529261
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006529320   ⟸   XM_006529257
- Peptide Label: isoform X1
- UniProtKB: S4R2V1 (UniProtKB/Swiss-Prot),   S4R1S4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138350   ⟸   ENSMUST00000183301
RefSeq Acc Id: ENSMUSP00000138275   ⟸   ENSMUST00000182755
RefSeq Acc Id: ENSMUSP00000141524   ⟸   ENSMUST00000193650
RefSeq Acc Id: ENSMUSP00000138800   ⟸   ENSMUST00000182283
RefSeq Acc Id: ENSMUSP00000142052   ⟸   ENSMUST00000195533
Protein Domains
Fibronectin type-III   Protein tyrosine phosphatase receptor type N-   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06800-F1-model_v2 AlphaFold P06800 1-1293 view protein structure

Promoters
RGD ID:6875126
Promoter ID:EPDNEW_M1014
Type:initiation region
Name:Ptprc_1
Description:Mus musculus protein tyrosine phosphatase, receptor type, C ,transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381138,175,299 - 138,175,359EPDNEW
RGD ID:6818330
Promoter ID:MM_KWN:2276
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   Spleen
Transcripts:ENSMUST00000112035
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361139,961,146 - 139,962,217 (-)MPROMDB
RGD ID:6818332
Promoter ID:MM_KWN:2277
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:UC007CVF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361140,013,079 - 140,013,579 (-)MPROMDB
RGD ID:6818334
Promoter ID:MM_KWN:2279
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000074797,   ENSMUST00000112038,   NM_001111316,   NM_011210,   UC007CVG.1,   UC007CVI.1,   UC007CVJ.1,   UC007CVK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361140,071,534 - 140,072,034 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97810 AgrOrtholog
Ensembl Genes ENSMUSG00000026395 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000138275 ENTREZGENE
  ENSMUSP00000138275.2 UniProtKB/TrEMBL
  ENSMUSP00000138350 ENTREZGENE
  ENSMUSP00000138350.2 UniProtKB/Swiss-Prot
  ENSMUSP00000138800 ENTREZGENE
  ENSMUSP00000138800.2 UniProtKB/Swiss-Prot
  ENSMUSP00000141524.2 UniProtKB/TrEMBL
  ENSMUSP00000142052.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000182283 ENTREZGENE
  ENSMUST00000182283.8 UniProtKB/Swiss-Prot
  ENSMUST00000182755 ENTREZGENE
  ENSMUST00000182755.8 UniProtKB/TrEMBL
  ENSMUST00000183301 ENTREZGENE
  ENSMUST00000183301.8 UniProtKB/Swiss-Prot
  ENSMUST00000193650.2 UniProtKB/TrEMBL
  ENSMUST00000195533.6 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTP_recept_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ptprc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97810 ENTREZGENE
NCBI Gene 19264 ENTREZGENE
PANTHER RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S UniProtKB/TrEMBL
Pfam CD45 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PTPRC RGD
PhenoGen Ptprc PhenoGen
PIRSF Leukocyte_common_antigen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWF2_MOUSE UniProtKB/TrEMBL
  A0A0A6YXM4_MOUSE UniProtKB/TrEMBL
  A1E2H6_MOUSE UniProtKB/TrEMBL
  P06800 ENTREZGENE, UniProtKB/Swiss-Prot
  Q05C79_MOUSE UniProtKB/TrEMBL
  Q3U382_MOUSE UniProtKB/TrEMBL
  Q5XFY7_MOUSE UniProtKB/TrEMBL
  Q8C6Q7 ENTREZGENE, UniProtKB/TrEMBL
  S4R1M0 ENTREZGENE, UniProtKB/TrEMBL
  S4R1S4 ENTREZGENE
  S4R2V1 ENTREZGENE
UniProt Secondary E9QLT5 UniProtKB/Swiss-Prot
  Q61812 UniProtKB/Swiss-Prot
  Q61813 UniProtKB/Swiss-Prot
  Q61814 UniProtKB/Swiss-Prot
  Q61815 UniProtKB/Swiss-Prot
  Q78EF1 UniProtKB/Swiss-Prot
  S4R1S4 UniProtKB/Swiss-Prot
  S4R2V1 UniProtKB/Swiss-Prot