Pnmt (phenylethanolamine-N-methyltransferase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Pnmt (phenylethanolamine-N-methyltransferase) Mus musculus
Analyze
Symbol: Pnmt
Name: phenylethanolamine-N-methyltransferase
RGD ID: 11126
MGI Page MGI
Description: Enables phenylethanolamine N-methyltransferase activity. Predicted to be involved in epinephrine biosynthetic process and norepinephrine metabolic process. Predicted to be located in axon; dendrite; and perikaryon. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; brain; gonad; and metanephros. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: noradrenaline N-methyltransferase; Pe; Pent; phenylethanolamine N-methyltransferase; PNMTase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,277,449 - 98,279,006 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1198,277,276 - 98,279,007 (+)EnsemblGRCm39 Ensembl
GRCm381198,386,623 - 98,388,180 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,386,450 - 98,388,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv371198,247,946 - 98,249,411 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361198,202,722 - 98,204,187 (+)NCBIMGSCv36mm8
Celera11108,040,856 - 108,042,321 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Regulation of the adrenomedullary catecholaminergic system after mild, acute stress. Betito K, etal., Am J Physiol. 1994 Jul;267(1 Pt 2):R212-20.
2. Activation of Different Neuronal Phenotypes in the Rat Brain Induced by Liver Ischemia-Reperfusion Injury: Dual Fos/Neuropeptide Immunohistochemistry. Bundzikova J, etal., Cell Mol Neurobiol. 2010 Nov 9.
3. Association of polymorphisms in the promoter region of the PNMT gene with essential hypertension in African Americans but not in whites. Cui J, etal., Am J Hypertens. 2003 Oct;16(10):859-63.
4. Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal system and hypothalamo-pituitary-adrenal axis. Inouye KE, etal., Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E422-9. Epub 2004 Oct 19.
5. Effects of insulin treatment without and with recurrent hypoglycemia on hypoglycemic counterregulation and adrenal catecholamine-synthesizing enzymes in diabetic rats. Inouye KE, etal., Endocrinology. 2006 Apr;147(4):1860-70. Epub 2006 Jan 5.
6. Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat. Jirout ML, etal., Hum Mol Genet. 2010 Jul 1;19(13):2567-80. Epub 2010 Apr 8.
7. Resequencing PNMT in European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1. Kepp K, etal., BMC Med Genet. 2007 Jul 23;8:47.
8. Catecholaminergic systems in stress: structural and molecular genetic approaches. Kvetnansky R, etal., Physiol Rev. 2009 Apr;89(2):535-606.
9. Phenylethanolamine N-methyltransferase (PNMT) gene and early-onset Alzheimer disease. Mann MB, etal., Am J Med Genet. 2001 May 8;105(4):312-6.
10. Association between the phenylethanolamine N-methyltransferase gene and multiple sclerosis. Mann MB, etal., J Neuroimmunol 2002 Mar;124(1-2):101-5.
11. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
12. MGDs mouse GO annotations MGD data from the GO Consortium
13. MGD IEA MGD IEA
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Expression levels of mRNAs for catecholamine biosynthetic enzymes as markers of acute response to contusion stress during the early postmortem period. Takahashi S Tohoku J Exp Med. 2008 Nov;216(3):239-48.
Additional References at PubMed
PMID:1320721   PMID:1348741   PMID:1542654   PMID:7628695   PMID:7931317   PMID:8000434   PMID:8221886   PMID:10349636   PMID:10357937   PMID:10552930   PMID:11042159   PMID:11076861  
PMID:11089558   PMID:11217851   PMID:11784869   PMID:12096893   PMID:12361965   PMID:12438096   PMID:12438097   PMID:12466851   PMID:12477932   PMID:12591599   PMID:12933902   PMID:14681479  
PMID:15517585   PMID:15824970   PMID:16141072   PMID:16141073   PMID:16176945   PMID:16467531   PMID:16602821   PMID:16691441   PMID:17196587   PMID:17478475   PMID:17698731   PMID:17853069  
PMID:18094025   PMID:18272785   PMID:19120124   PMID:20118198   PMID:20351116   PMID:20619316   PMID:20875861   PMID:21267068   PMID:21818395   PMID:21873635   PMID:22580128   PMID:22706789  
PMID:22962254   PMID:23204390   PMID:23268986   PMID:23648511   PMID:24194600   PMID:24565998   PMID:24677751   PMID:25071457   PMID:25093893   PMID:25661788   PMID:25989220   PMID:26909542  
PMID:27576662   PMID:27626380   PMID:28084430   PMID:28228269   PMID:28700664   PMID:29043563   PMID:29879378   PMID:30319349   PMID:30850723   PMID:31677273   PMID:33052459   PMID:33192300  
PMID:33500353   PMID:35263575   PMID:35665220   PMID:36774552   PMID:38164795   PMID:38355793  


Genomics

Comparative Map Data
Pnmt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,277,449 - 98,279,006 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1198,277,276 - 98,279,007 (+)EnsemblGRCm39 Ensembl
GRCm381198,386,623 - 98,388,180 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,386,450 - 98,388,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv371198,247,946 - 98,249,411 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361198,202,722 - 98,204,187 (+)NCBIMGSCv36mm8
Celera11108,040,856 - 108,042,321 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.75NCBI
PNMT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381739,668,019 - 39,670,475 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1739,667,981 - 39,670,475 (+)EnsemblGRCh38hg38GRCh38
GRCh371737,824,272 - 37,826,728 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,078,033 - 35,080,254 (+)NCBINCBI36Build 36hg18NCBI36
Build 341735,078,032 - 35,080,254NCBI
Celera1734,484,236 - 34,486,457 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1733,618,165 - 33,620,658 (+)NCBIHuRef
CHM1_11738,060,055 - 38,062,549 (+)NCBICHM1_1
T2T-CHM13v2.01740,531,584 - 40,534,040 (+)NCBIT2T-CHM13v2.0
Pnmt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81083,881,211 - 83,882,849 (+)NCBIGRCr8
mRatBN7.21083,383,019 - 83,386,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1083,384,923 - 83,386,556 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1088,329,223 - 88,330,891 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01087,827,308 - 87,828,976 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01083,219,959 - 83,221,627 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01086,340,893 - 86,342,501 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,340,940 - 86,342,858 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01086,137,019 - 86,138,436 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1082,132,183 - 82,134,127 (+)NCBICelera
Cytogenetic Map10q31NCBI
Pnmt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545114,416,121 - 14,417,901 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545114,414,836 - 14,417,972 (+)NCBIChiLan1.0ChiLan1.0
PNMT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21925,284,931 - 25,287,216 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11727,179,738 - 27,182,015 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01717,618,399 - 17,620,691 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11717,835,277 - 17,837,180 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1717,835,277 - 17,837,180 (-)Ensemblpanpan1.1panPan2
PNMT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,808,505 - 22,810,587 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,808,601 - 22,810,551 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha922,280,958 - 22,282,522 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0923,602,151 - 23,603,715 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl923,602,151 - 23,604,794 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1922,374,797 - 22,376,361 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0922,635,796 - 22,637,358 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,760,897 - 22,762,461 (-)NCBIUU_Cfam_GSD_1.0
Pnmt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560222,213,520 - 22,217,186 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649014,858,603 - 14,865,321 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649014,858,682 - 14,861,614 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNMT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,648,398 - 22,649,999 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11222,648,396 - 22,651,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21223,110,418 - 23,111,803 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PNMT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,496,290 - 66,498,840 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1666,496,027 - 66,499,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607737,407,873 - 37,410,511 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnmt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,408,627 - 3,410,304 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,408,559 - 3,410,669 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pnmt
50 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:466
Count of miRNA genes:381
Interacting mature miRNAs:417
Transcripts:ENSMUST00000041301, ENSMUST00000124527
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1301153Estq3_mestradiol regulated response QTL 3 (mouse)Not determined119689769399327028Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118869958899081597Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse

Markers in Region
L12687  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381198,388,190 - 98,388,342UniSTSGRCm38
MGSCv371198,249,504 - 98,249,656UniSTSGRCm37
Celera11108,042,414 - 108,042,566UniSTS
Cytogenetic Map11DUniSTS
Whitehead_YAC11 UniSTS
AI503981  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381198,384,769 - 98,384,863UniSTSGRCm38
MGSCv371198,246,083 - 98,246,177UniSTSGRCm37
Celera11108,038,993 - 108,039,087UniSTS
Cytogenetic Map11DUniSTS
Whitehead/MRC_RH111308.14UniSTS
Whitehead/MRC_RH111306.72UniSTS
UniSTS:491268  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381198,386,602 - 98,388,197UniSTSGRCm38
MGSCv371198,247,916 - 98,249,511UniSTSGRCm37
Celera11108,040,826 - 108,042,421UniSTS
Cytogenetic Map11DUniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000041301   ⟹   ENSMUSP00000035549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1198,277,276 - 98,279,007 (+)Ensembl
GRCm38.p6 Ensembl1198,386,450 - 98,388,181 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124527
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1198,277,538 - 98,278,308 (+)Ensembl
GRCm38.p6 Ensembl1198,386,712 - 98,387,482 (+)Ensembl
RefSeq Acc Id: NM_008890   ⟹   NP_032916
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391198,277,449 - 98,279,006 (+)NCBI
GRCm381198,386,623 - 98,388,180 (+)NCBI
MGSCv371198,247,946 - 98,249,411 (+)RGD
Celera11108,040,856 - 108,042,321 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032916 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA68934 (Get FASTA)   NCBI Sequence Viewer  
  AAI19080 (Get FASTA)   NCBI Sequence Viewer  
  AAI20790 (Get FASTA)   NCBI Sequence Viewer  
  EDL16137 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000035549
  ENSMUSP00000035549.8
GenBank Protein P40935 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032916   ⟸   NM_008890
- UniProtKB: P40935 (UniProtKB/Swiss-Prot),   Q0VB50 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000035549   ⟸   ENSMUST00000041301

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P40935-F1-model_v2 AlphaFold P40935 1-295 view protein structure

Promoters
RGD ID:8676486
Promoter ID:EPDNEW_M16273
Type:multiple initiation site
Name:Pnmt_1
Description:Mus musculus phenylethanolamine-N-methyltransferase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381198,386,626 - 98,386,686EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97724 AgrOrtholog
Ensembl Genes ENSMUSG00000038216 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000041301 ENTREZGENE
  ENSMUST00000041301.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NNMT/PNMT/TEMT_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NNMT_TEMT_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dep_methyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18948 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97724 ENTREZGENE
NCBI Gene 18948 ENTREZGENE
PANTHER PHENYLETHANOLAMINE N-METHYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10867 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NNMT_PNMT_TEMT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PNMT RGD
PhenoGen Pnmt PhenoGen
PIRSF PNMTase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NNMT_PNMT_TEMT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_MT_NNMT_PNMT_TEMT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P40935 ENTREZGENE, UniProtKB/Swiss-Prot
  Q0VB50 ENTREZGENE, UniProtKB/TrEMBL