P4hb (prolyl 4-hydroxylase, beta polypeptide) - Rat Genome Database

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Advanced Search (OLGA)
Gene: P4hb (prolyl 4-hydroxylase, beta polypeptide) Mus musculus
Analyze
Symbol: P4hb
Name: prolyl 4-hydroxylase, beta polypeptide
RGD ID: 11046
MGI Page MGI
Description: Enables integrin binding activity and protein-disulfide reductase activity. Involved in insulin processing. Acts upstream of with a positive effect on endoplasmic reticulum to Golgi vesicle-mediated transport. Acts upstream of or within cellular response to interleukin-7. Located in endoplasmic reticulum and external side of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is active in endoplasmic reticulum lumen. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to human P4HB (prolyl 4-hydroxylase subunit beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cellular thyroid hormone-binding protein; endoplasmic reticulum resident protein 59; ER protein 59; ERp; ERp59; P; p55; Pd; PDI; Pdia1; prolyl 4-hydroxylase subunit beta; protein disulfide isomerase; protein disulfide-isomerase; Thb; Thbp
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,451,124 - 120,464,079 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,451,124 - 120,464,079 (-)EnsemblGRCm39 Ensembl
GRCm3811120,560,298 - 120,573,253 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,560,298 - 120,573,253 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,421,618 - 120,434,250 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,376,394 - 120,389,026 (-)NCBIMGSCv36mm8
Celera11132,295,664 - 132,308,296 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dichlorophenol  (ISO)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (ISO)
3,3',5'-triiodo-L-thyronine  (ISO)
3,3',5'-triiodothyronine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allopurinol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (ISO)
bromobenzene  (ISO)
bucladesine  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcidiol  (ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
ethanol  (EXP)
fenofibrate  (ISO)
fenthion  (EXP)
fluoxetine  (ISO)
folic acid  (EXP)
folpet  (EXP)
furan  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glucose  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
indinavir  (ISO)
indometacin  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
L-serine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
medroxyprogesterone acetate  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methotrexate  (ISO)
motexafin gadolinium  (ISO)
N-nitrosomorpholine  (ISO)
N-Phenylmaleimide  (ISO)
nafenopin  (ISO)
naphthalene  (EXP)
nicotine  (ISO)
obeticholic acid  (ISO)
oxidopamine  (ISO)
ozone  (EXP)
paracetamol  (EXP)
pentachlorophenol  (ISO)
perfluorododecanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylarsonous acid  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procymidone  (ISO)
Propiverine  (ISO)
quercetin  (ISO)
rifampicin  (ISO)
S-nitrosoglutathione  (ISO)
sarin  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
Soman  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
testosterone  (EXP)
Tetrachlorobisphenol A  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
triadimefon  (ISO)
troglitazone  (ISO)
tunicamycin  (EXP,ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vinclozolin  (ISO)
zearalenone  (EXP)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Proteins of the PDI family: unpredicted non-ER locations and functions. Turano C, etal., J Cell Physiol 2002 Nov;193(2):154-63.
Additional References at PubMed
PMID:1694844   PMID:1794055   PMID:2295602   PMID:2830592   PMID:7527040   PMID:7557995   PMID:7753822   PMID:7789972   PMID:8070621   PMID:8282096   PMID:8449498   PMID:8563764  
PMID:8661048   PMID:8683100   PMID:8717055   PMID:8938438   PMID:9177778   PMID:9344654   PMID:9367786   PMID:9457688   PMID:9493907   PMID:9507200   PMID:9806833   PMID:9806850  
PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12475965   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14561754  
PMID:14622145   PMID:14681479   PMID:14693722   PMID:15110751   PMID:15146195   PMID:15747579   PMID:15767459   PMID:15767678   PMID:15782199   PMID:15840001   PMID:16141072   PMID:16141073  
PMID:16416089   PMID:16902998   PMID:17090218   PMID:18094359   PMID:18554416   PMID:19147124   PMID:19822367   PMID:19966784   PMID:20484573   PMID:20668226   PMID:21267068   PMID:21512159  
PMID:21670307   PMID:21677750   PMID:21873635   PMID:22653978   PMID:23118353   PMID:23152784   PMID:23460613   PMID:23477350   PMID:23788140   PMID:24194600   PMID:26147683   PMID:26218911  
PMID:26370502   PMID:26383973   PMID:26529254   PMID:26816051   PMID:27626380   PMID:28053051   PMID:28106071   PMID:28202523   PMID:28378742   PMID:29581031   PMID:29709484   PMID:29924999  
PMID:30121012   PMID:30257707   PMID:30550785   PMID:30586735   PMID:30635284   PMID:30713523   PMID:31162944   PMID:31184304   PMID:31487503   PMID:32038174   PMID:32325033   PMID:33227407  
PMID:33863978   PMID:34487921   PMID:35385753   PMID:35984546   PMID:36048019   PMID:36114006   PMID:36293380   PMID:36417873   PMID:36427672   PMID:36463755   PMID:37142655   PMID:38042368  
PMID:38103869   PMID:38211723   PMID:38355793   PMID:38400621  


Genomics

Comparative Map Data
P4hb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,451,124 - 120,464,079 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,451,124 - 120,464,079 (-)EnsemblGRCm39 Ensembl
GRCm3811120,560,298 - 120,573,253 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,560,298 - 120,573,253 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,421,618 - 120,434,250 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,376,394 - 120,389,026 (-)NCBIMGSCv36mm8
Celera11132,295,664 - 132,308,296 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.27NCBI
P4HB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,843,166 - 81,860,535 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,843,159 - 81,860,856 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,801,042 - 79,818,411 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,394,323 - 77,411,833 (-)NCBINCBI36Build 36hg18NCBI36
Celera1776,404,498 - 76,422,010 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,202,821 - 75,220,332 (-)NCBIHuRef
CHM1_11779,887,239 - 79,904,780 (-)NCBICHM1_1
T2T-CHM13v2.01782,710,331 - 82,727,700 (-)NCBIT2T-CHM13v2.0
P4hb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,335,300 - 106,346,911 (-)NCBIGRCr8
mRatBN7.210105,836,972 - 105,848,583 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,836,982 - 105,848,500 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,941,098 - 110,952,604 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,404,126 - 110,415,632 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,757,420 - 105,769,031 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,736,459 - 109,748,070 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,736,458 - 109,747,987 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,329,596 - 109,341,091 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,950,221 - 109,961,716 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110109,964,724 - 109,976,220 (-)NCBI
Celera10104,380,384 - 104,391,995 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
P4hb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,307,932 - 1,324,027 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,307,932 - 1,322,011 (+)NCBIChiLan1.0ChiLan1.0
P4HB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,378,767 - 98,396,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,279,545 - 103,297,401 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,248,252 - 76,266,152 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11781,950,826 - 81,968,329 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1781,950,422 - 81,968,109 (-)Ensemblpanpan1.1panPan2
P4HB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19427,827 - 436,880 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9427,830 - 436,064 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha91,029,990 - 1,039,034 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.091,021,195 - 1,030,242 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl91,021,122 - 1,030,242 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.191,046,356 - 1,055,402 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,172,930 - 1,181,988 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,251,854 - 1,260,908 (+)NCBIUU_Cfam_GSD_1.0
P4hb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056021,032,744 - 1,043,760 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,367,816 - 5,379,252 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,368,199 - 5,379,215 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P4HB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,121,824 - 1,131,289 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,121,816 - 1,131,291 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
P4HB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,718,743 - 73,733,488 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,718,656 - 73,733,892 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,170,359 - 45,185,570 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
P4hb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,699,161 - 10,712,896 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,700,301 - 10,712,889 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in P4hb
514 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:579
Count of miRNA genes:374
Interacting mature miRNAs:406
Transcripts:ENSMUST00000026122, ENSMUST00000166620, ENSMUST00000168360
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse

Markers in Region
Pdia3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11D-EUniSTS
Cytogenetic Map2E5UniSTS
cM Map269.0UniSTS
UniSTS:236789  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,566,377 - 120,566,555UniSTSGRCm38
MGSCv3711120,427,691 - 120,427,869UniSTSGRCm37
Celera11132,301,737 - 132,301,915UniSTS
Cytogenetic Map11D-EUniSTS
P4hb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,560,373 - 120,560,533UniSTSGRCm38
MGSCv3711120,421,687 - 120,421,847UniSTSGRCm37
Celera11132,295,733 - 132,295,893UniSTS
Cytogenetic Map11D-EUniSTS
cM Map1180.0UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK141304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP766087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA317831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000026122   ⟹   ENSMUSP00000026122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11120,451,124 - 120,464,079 (-)Ensembl
GRCm38.p6 Ensembl11120,560,298 - 120,573,253 (-)Ensembl
Ensembl Acc Id: ENSMUST00000166620
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11120,451,131 - 120,452,062 (-)Ensembl
GRCm38.p6 Ensembl11120,560,305 - 120,561,236 (-)Ensembl
Ensembl Acc Id: ENSMUST00000168360   ⟹   ENSMUSP00000128796
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11120,451,771 - 120,463,667 (-)Ensembl
GRCm38.p6 Ensembl11120,560,945 - 120,572,841 (-)Ensembl
RefSeq Acc Id: NM_011032   ⟹   NP_035162
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911120,451,124 - 120,464,079 (-)NCBI
GRCm3811120,560,298 - 120,573,253 (-)NCBI
MGSCv3711120,421,618 - 120,434,250 (-)RGD
Celera11132,295,664 - 132,308,296 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_035162 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA39906 (Get FASTA)   NCBI Sequence Viewer  
  AAH08549 (Get FASTA)   NCBI Sequence Viewer  
  AAH93512 (Get FASTA)   NCBI Sequence Viewer  
  BAE24642 (Get FASTA)   NCBI Sequence Viewer  
  BAE27247 (Get FASTA)   NCBI Sequence Viewer  
  BAE28987 (Get FASTA)   NCBI Sequence Viewer  
  BAE29199 (Get FASTA)   NCBI Sequence Viewer  
  BAE29230 (Get FASTA)   NCBI Sequence Viewer  
  BAE29545 (Get FASTA)   NCBI Sequence Viewer  
  BAE29825 (Get FASTA)   NCBI Sequence Viewer  
  BAE29868 (Get FASTA)   NCBI Sequence Viewer  
  BAE30327 (Get FASTA)   NCBI Sequence Viewer  
  BAE30492 (Get FASTA)   NCBI Sequence Viewer  
  BAE30979 (Get FASTA)   NCBI Sequence Viewer  
  BAE31045 (Get FASTA)   NCBI Sequence Viewer  
  BAE31534 (Get FASTA)   NCBI Sequence Viewer  
  BAE35225 (Get FASTA)   NCBI Sequence Viewer  
  BAE35323 (Get FASTA)   NCBI Sequence Viewer  
  BAE35520 (Get FASTA)   NCBI Sequence Viewer  
  BAE36449 (Get FASTA)   NCBI Sequence Viewer  
  BAE39791 (Get FASTA)   NCBI Sequence Viewer  
  BAE39826 (Get FASTA)   NCBI Sequence Viewer  
  BAE40268 (Get FASTA)   NCBI Sequence Viewer  
  BAE40274 (Get FASTA)   NCBI Sequence Viewer  
  BAE40478 (Get FASTA)   NCBI Sequence Viewer  
  BAE40710 (Get FASTA)   NCBI Sequence Viewer  
  BAE41026 (Get FASTA)   NCBI Sequence Viewer  
  BAE41907 (Get FASTA)   NCBI Sequence Viewer  
  CAA29759 (Get FASTA)   NCBI Sequence Viewer  
  EDL34765 (Get FASTA)   NCBI Sequence Viewer  
  EDL34766 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000026122
  ENSMUSP00000026122.5
  ENSMUSP00000128796.2
GenBank Protein P09103 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_035162   ⟸   NM_011032
- Peptide Label: precursor
- UniProtKB: Q922C8 (UniProtKB/Swiss-Prot),   P09103 (UniProtKB/Swiss-Prot),   Q3TWE3 (UniProtKB/TrEMBL),   Q3UA23 (UniProtKB/TrEMBL),   Q3UBY9 (UniProtKB/TrEMBL),   Q3UJA8 (UniProtKB/TrEMBL),   Q3URP6 (UniProtKB/TrEMBL),   Q3TF72 (UniProtKB/TrEMBL),   Q3TGS0 (UniProtKB/TrEMBL),   Q3THC3 (UniProtKB/TrEMBL),   Q3TIM0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000026122   ⟸   ENSMUST00000026122
Ensembl Acc Id: ENSMUSP00000128796   ⟸   ENSMUST00000168360
Protein Domains
Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09103-F1-model_v2 AlphaFold P09103 1-509 view protein structure

Promoters
RGD ID:6846876
Promoter ID:MM_ACW:9626
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour
Transcripts:P4HB.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,424,941 - 120,425,441 (-)MPROMDB
RGD ID:6846872
Promoter ID:MM_ACW:9627
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Liver
Transcripts:P4HB.CSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,432,561 - 120,433,061 (-)MPROMDB
RGD ID:6821495
Promoter ID:MM_KWN:10934
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000009214
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,434,101 - 120,435,367 (-)MPROMDB
RGD ID:8677692
Promoter ID:EPDNEW_M16877
Type:initiation region
Name:P4hb_1
Description:Mus musculus prolyl 4-hydroxylase, beta polypeptide , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811120,572,873 - 120,572,933EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97464 AgrOrtholog
Ensembl Genes ENSMUSG00000025130 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026122 ENTREZGENE
  ENSMUST00000026122.11 UniProtKB/Swiss-Prot
  ENSMUST00000168360.2 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Disulphide_isomerase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_disulphide_isomerase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18453 UniProtKB/Swiss-Prot
MGD MGI:97464 ENTREZGENE
NCBI Gene 18453 ENTREZGENE
PANTHER PROTEIN DISULFIDE ISOMERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN DISULFIDE-ISOMERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen P4hb PhenoGen
PRINTS THIOREDOXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ER_TARGET UniProtKB/Swiss-Prot
  THIOREDOXIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9Q8G8_MOUSE UniProtKB/TrEMBL
  P09103 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TF72 ENTREZGENE, UniProtKB/TrEMBL
  Q3TGS0 ENTREZGENE, UniProtKB/TrEMBL
  Q3THC3 ENTREZGENE, UniProtKB/TrEMBL
  Q3TIM0 ENTREZGENE, UniProtKB/TrEMBL
  Q3TIQ5_MOUSE UniProtKB/TrEMBL
  Q3TT76_MOUSE UniProtKB/TrEMBL
  Q3TWE3 ENTREZGENE, UniProtKB/TrEMBL
  Q3U738_MOUSE UniProtKB/TrEMBL
  Q3UA23 ENTREZGENE, UniProtKB/TrEMBL
  Q3UBY9 ENTREZGENE, UniProtKB/TrEMBL
  Q3UDR2_MOUSE UniProtKB/TrEMBL
  Q3UJA8 ENTREZGENE, UniProtKB/TrEMBL
  Q3URP6 ENTREZGENE, UniProtKB/TrEMBL
  Q922C8 ENTREZGENE
UniProt Secondary Q922C8 UniProtKB/Swiss-Prot