Ntrk2 (neurotrophic tyrosine kinase, receptor, type 2) - Rat Genome Database

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Gene: Ntrk2 (neurotrophic tyrosine kinase, receptor, type 2) Mus musculus
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Symbol: Ntrk2
Name: neurotrophic tyrosine kinase, receptor, type 2
RGD ID: 11023
MGI Page MGI
Description: Enables brain-derived neurotrophic factor binding activity and brain-derived neurotrophic factor receptor activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; modulation of chemical synaptic transmission; and nervous system development. Acts upstream of or within several processes, including neurogenesis; neuronal action potential propagation; and positive regulation of peptidyl-serine phosphorylation. Located in several cellular components, including early endosome; postsynaptic density; and terminal bouton. Is expressed in several structures, including alimentary system; cardiovascular system; future brain; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; autistic disorder; developmental and epileptic encephalopathy 58; major depressive disorder; and morbid obesity. Orthologous to human NTRK2 (neurotrophic receptor tyrosine kinase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI848316; BDNF/NT-3 growth factors receptor; C030027L06Rik; GP145-TrkB/GP95-TrkB; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine receptor kinase type 2; Tkr; Tkrb; trk; trk-B; trkB; trkB tyrosine kinase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,954,363 - 59,281,782 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,954,383 - 59,281,784 (+)EnsemblGRCm39 Ensembl
GRCm381358,806,472 - 59,133,970 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,806,569 - 59,133,970 (+)EnsemblGRCm38mm10GRCm38
MGSCv371358,907,957 - 59,231,337 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361358,816,219 - 59,139,599 (+)NCBIMGSCv36mm8
Celera1359,869,829 - 60,184,466 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1331.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-syringaresinol beta-D-glucoside  (EXP)
(20S)-ginsenoside Rg3  (EXP,ISO)
(S)-amphetamine  (EXP)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (EXP)
1-fluoro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-nitropropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Solamarine  (EXP)
amitrole  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
androgen antagonist  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (ISO)
arsanilic acid  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
buprenorphine  (ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
Butylparaben  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
CGS-21680  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
citalopram  (EXP)
Citreoviridin  (EXP)
clomipramine  (EXP)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
cyproconazole  (EXP)
DDD  (ISO)
DDE  (ISO)
DDT  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
dioxygen  (ISO)
disodium selenite  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
echinacoside  (ISO)
endrin  (ISO)
entinostat  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
fenvalerate  (EXP,ISO)
fipronil  (ISO)
flavonoids  (ISO)
fluoxetine  (EXP,ISO)
folic acid  (EXP)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (EXP)
graphite  (ISO)
heroin  (ISO)
hydrogen peroxide  (EXP,ISO)
imipramine  (EXP)
indometacin  (ISO)
inulin  (EXP)
isotretinoin  (ISO)
kainic acid  (ISO)
ketamine  (EXP,ISO)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP)
lycopene  (ISO)
malathion  (ISO)
maneb  (EXP)
manganese(II) chloride  (EXP)
melatonin  (EXP)
metformin  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methylglyoxal  (ISO)
methyllycaconitine  (ISO)
methylmercury chloride  (EXP)
methylphenidate  (ISO)
mifepristone  (ISO)
morin  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (EXP)
N-ethyl-N-nitrosourea  (ISO)
naphthalene  (EXP)
naphthalenes  (ISO)
nickel atom  (ISO)
nicotine  (EXP,ISO)
nicotinic acid  (ISO)
Nonylphenol  (EXP,ISO)
oleuropein  (EXP)
papaverine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
permethrin  (ISO)
Phenelzine  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
physostigmine  (EXP)
pirinixic acid  (EXP)
ponatinib  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
Ptaquiloside  (EXP)
quartz  (EXP)
reboxetine  (EXP)
reserpine  (EXP)
rolipram  (EXP,ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
SB 431542  (ISO)
scopolamine  (EXP,ISO)
sevoflurane  (EXP)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
Soman  (ISO)
sterigmatocystin  (ISO)
streptozocin  (EXP,ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
T-2 toxin  (ISO)
tacrine  (EXP)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
Tetrachlorobisphenol A  (ISO)
titanium dioxide  (EXP)
toluene  (EXP)
tranylcypromine  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
undecane  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
WIN 55212-2  (EXP)
zalcitabine  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
brain-derived neurotrophic factor receptor signaling pathway  (IDA,ISO)
calcium-mediated signaling using intracellular calcium source  (IMP)
cell differentiation  (IEA)
cell surface receptor protein tyrosine kinase signaling pathway  (IEA)
cellular response to amino acid stimulus  (IDA)
cellular response to brain-derived neurotrophic factor stimulus  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to tumor necrosis factor  (ISO)
central nervous system neuron development  (IMP)
cerebral cortex development  (IMP)
circadian rhythm  (IEP)
feeding behavior  (IMP)
glutamate secretion  (IPI)
learning  (IMP)
long-term memory  (ISO)
long-term synaptic potentiation  (IMP)
mechanoreceptor differentiation  (IMP)
myelination in peripheral nervous system  (IGI)
negative regulation of amyloid-beta formation  (ISO)
negative regulation of anoikis  (IDA)
negative regulation of neuron apoptotic process  (ISO)
nervous system development  (IEA)
neuromuscular junction development  (IMP)
neuron differentiation  (IMP)
neuron migration  (IMP)
neuronal action potential propagation  (IGI)
oligodendrocyte differentiation  (IMP)
peripheral nervous system neuron development  (IMP)
positive regulation of axonogenesis  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of gene expression  (IMP)
positive regulation of glucocorticoid receptor signaling pathway  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of neuron projection development  (IDA)
positive regulation of peptidyl-serine phosphorylation  (IMP)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of synapse assembly  (IDA)
positive regulation of synaptic transmission, glutamatergic  (ISO)
protein autophosphorylation  (ISO)
regulation of dendrite development  (ISO)
regulation of MAPK cascade  (ISO)
regulation of metabolic process  (IMP)
regulation of neurotransmitter secretion  (ISO)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP)
response to auditory stimulus  (ISO)
response to ethanol  (ISO)
response to light stimulus  (ISO)
retina development in camera-type eye  (IMP)
retinal rod cell development  (IMP)
trans-synaptic signaling by BDNF, modulating synaptic transmission  (IDA,IMP)
trans-synaptic signaling by neuropeptide, modulating synaptic transmission  (IMP)
vasculogenesis  (IMP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue distribution  (IAGP)
abnormal amygdala morphology  (IAGP)
abnormal avoidance learning behavior  (IAGP)
abnormal axon extension  (IAGP)
abnormal axon fasciculation  (IAGP)
abnormal barrel cortex morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal circadian behavior  (IAGP)
abnormal circulating corticosterone level  (IAGP)
abnormal cochlear ganglion morphology  (IAGP)
abnormal cochlear nerve morphology  (IAGP)
abnormal cochlear OHC afferent innervation pattern  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal contextual conditioning behavior  (IAGP)
abnormal cortical plate morphology  (IAGP)
abnormal crista ampullaris neuroepithelium morphology  (IAGP)
abnormal dendrite morphology  (IAGP)
abnormal distortion product otoacoustic emission  (IAGP)
abnormal dopaminergic neuron morphology  (IAGP)
abnormal excitatory postsynaptic potential  (IAGP)
abnormal eyelid morphology  (IAGP)
abnormal GABAergic neuron physiology  (IAGP)
abnormal gait  (IAGP)
abnormal inner ear vestibule morphology  (IAGP)
abnormal innervation  (IAGP)
abnormal learning/memory/conditioning  (IAGP)
abnormal lipid level  (IAGP)
abnormal liver morphology  (IAGP)
abnormal long-term potentiation  (IAGP)
abnormal mechanoreceptor morphology  (IAGP)
abnormal myelin sheath morphology  (IAGP)
abnormal myelination  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal optic nerve morphology  (IAGP)
abnormal peripheral nervous system regeneration  (IAGP)
abnormal pupillary reflex  (IAGP)
abnormal Purkinje cell dendrite morphology  (IAGP)
abnormal response to novel object  (IAGP)
abnormal retina development  (IAGP)
abnormal retina ganglion cell morphology  (IAGP)
abnormal retina rod cell outer segment morphology  (IAGP)
abnormal rib morphology  (IEA)
abnormal rod electrophysiology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal somatic nervous system morphology  (IAGP)
abnormal somatic sensory system morphology  (IAGP)
abnormal somatosensory cortex morphology  (IAGP)
abnormal spatial learning  (IAGP)
abnormal spatial working memory  (IAGP)
abnormal survival  (IAGP)
abnormal synapse morphology  (IAGP)
abnormal type I vestibular cell  (IAGP)
abnormal utricular macula morphology  (IAGP)
abnormal vestibular ganglion morphology  (IAGP)
abnormal vestibular labyrinth morphology  (IAGP)
abnormal vestibular nerve morphology  (IAGP)
abnormal vestibulocochlear nerve morphology  (IAGP)
abnormal vibrissae reflex  (IAGP)
abnormal vision  (IAGP)
abnormal visual cortex morphology  (IAGP)
absent hair-down neurons  (IAGP)
absent suckling reflex  (IAGP)
adrenal cortical hyperplasia  (IAGP)
astrocytosis  (IAGP)
decreased amacrine cell number  (IAGP)
decreased birth body size  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased circulating adrenocorticotropin level  (IAGP)
decreased circulating corticosterone level  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased dopaminergic neuron number  (IAGP)
decreased granulosa cell proliferation  (IAGP)
decreased kindling response  (IAGP)
decreased locomotor activity  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased motor neuron number  (IAGP)
decreased neuron number  (IAGP)
decreased prepulse inhibition  (IEA)
decreased retina ganglion cell number  (IAGP)
decreased secondary ovarian follicle number  (IAGP)
decreased sensory neuron number  (IAGP)
decreased width of hypertrophic chondrocyte zone  (IAGP)
demyelination  (IAGP)
enhanced behavioral response to cocaine  (IAGP)
gliosis  (IAGP)
head bobbing  (IAGP)
hepatic steatosis  (IAGP)
hyperactivity  (IAGP)
impaired glucose tolerance  (IAGP)
impaired granulosa cell differentiation  (IAGP)
impaired ovarian folliculogenesis  (IAGP)
impaired righting response  (IAGP)
impaired synaptic plasticity  (IAGP)
increased abdominal fat pad weight  (IAGP)
increased adrenal gland zona fasciculata size  (IAGP)
increased aggression towards male mice  (IAGP)
increased body weight  (IAGP)
increased circulating adrenocorticotropin level  (IAGP)
increased circulating HDL cholesterol level  (IEA)
increased circulating insulin level  (IAGP)
increased circulating leptin level  (IAGP)
increased gonadal fat pad weight  (IAGP)
increased lean body mass  (IEA)
increased liver weight  (IAGP)
increased locomotor activity  (IAGP)
increased susceptibility to age related obesity  (IAGP)
increased susceptibility to dopaminergic neuron neurotoxicity  (IAGP)
increased susceptibility to weight gain  (IAGP)
increased thigmotaxis  (IAGP)
increased total body fat amount  (IAGP)
induced hyperactivity  (IAGP)
kyphosis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
neurodegeneration  (IAGP)
no abnormal phenotype detected  (IAGP)
no swallowing reflex  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
reduced long-term potentiation  (IAGP)
small cochlear ganglion  (IAGP)
small dorsal root ganglion  (IAGP)
small facial motor nucleus  (IAGP)
small geniculate ganglion  (IAGP)
small L4 dorsal root ganglion  (IAGP)
small nodose ganglion  (IAGP)
small petrosal ganglion  (IAGP)
small trigeminal ganglion  (IAGP)
small vestibular ganglion  (IAGP)
spinning  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis. Avcuoglu S, etal., Am J Respir Cell Mol Biol. 2011 Oct;45(4):768-80. Epub 2011 Feb 17.
2. Up-regulation of high-affinity neurotrophin receptor, trk B-like protein on western blots of rat cortex after chronic ethanol treatment. Baek JK, etal., Brain Res Mol Brain Res. 1996 Aug;40(1):161-4. doi: 10.1016/0169-328x(96)00109-x.
3. An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma. Bai Y, etal., Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4722-31. Epub 2010 Mar 31.
4. Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor. Cao XH, etal., J Neurochem. 2010 Sep 1;114(5):1460-75. Epub 2010 Jun 24.
5. Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism. Correia CT, etal., Genes Brain Behav. 2010 Oct;9(7):841-8. doi: 10.1111/j.1601-183X.2010.00627.x. Epub 2010 Aug 19.
6. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. Cortese GP, etal., J Neurosci. 2011 Mar 16;31(11):4274-9.
7. SNPs in neurotrophin system genes and Alzheimer's disease in an Italian population. Cozza A, etal., J Alzheimers Dis. 2008 Sep;15(1):61-70.
8. [Effects of chaihu shugan powder on the behavior and expressions of BDNF and TrkB in the hippocampus, amygdala, and the frontal lobe in rat model of depression]. Deng Y, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Oct;31(10):1373-8.
9. 7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, Reverses Memory Deficits and BACE1 Elevation in a Mouse Model of Alzheimer's Disease. Devi L and Ohno M, Neuropsychopharmacology. 2012 Jan;37(2):434-44. doi: 10.1038/npp.2011.191. Epub 2011 Sep 7.
10. Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans. Dong C, etal., Mol Psychiatry. 2009 Dec;14(12):1105-18. Epub 2009 Oct 20.
11. Prenatal stress leads to chromatin and synaptic remodeling and excessive alcohol intake comorbid with anxiety-like behaviors in adult offspring. Dong E, etal., Neuropharmacology. 2018 Sep 15;140:76-85. doi: 10.1016/j.neuropharm.2018.07.010. Epub 2018 Aug 4.
12. A TrkB antibody agonist promotes plasticity following cervical spinal cord injury in adult rats. Fouad K, etal., J Neurotrauma. 2010 Jul 2.
13. Intermittent noxious stimulation following spinal cord contusion injury impairs locomotor recovery and reduces spinal brain-derived neurotrophic factor-tropomyosin-receptor kinase signaling in adult rats. Garraway SM, etal., Neuroscience. 2011 Dec 29;199:86-102. Epub 2011 Oct 18.
14. Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity. Gray J, etal., Int J Obes (Lond). 2007 Feb;31(2):359-64. Epub 2006 May 16.
15. TrkB receptor signalling: implications in neurodegenerative, psychiatric and proliferative disorders. Gupta VK, etal., Int J Mol Sci. 2013 May 13;14(5):10122-42. doi: 10.3390/ijms140510122.
16. Preservation of tropomyosin-related kinase B (TrkB) signaling by sodium orthovanadate attenuates early brain injury after subarachnoid hemorrhage in rats. Hasegawa Y, etal., Stroke. 2011 Feb;42(2):477-83. Epub 2010 Dec 30.
17. Disruption of TrkB-mediated phospholipase Cgamma signaling inhibits limbic epileptogenesis. He XP, etal., J Neurosci. 2010 May 5;30(18):6188-96.
18. Treadmill exercise improves spatial learning ability by enhancing brain-derived neurotrophic factor expression in the attention-deficit/hyperactivity disorder rats. Jeong HI, etal., J Exerc Rehabil. 2014 Jun 30;10(3):162-7. doi: 10.12965/jer.140111. eCollection 2014 Jun.
19. Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Kohli MA, etal., Arch Gen Psychiatry. 2010 Apr;67(4):348-59. Epub 2010 Feb 1.
20. Dynamic changes of TrkB gene expression in Streptococcus pneumoniae meningitis after treatment with antibiotics and dexamethasone. Li L, etal., World J Pediatr. 2011 Aug;7(3):250-6. Epub 2011 May 20.
21. Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study. Lin YT, etal., J Neuroinflammation. 2011 Sep 30;8:126. doi: 10.1186/1742-2094-8-126.
22. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
23. MGDs mouse GO annotations MGD data from the GO Consortium
24. MGD IEA MGD IEA
25. Differential regulation of the expression of neurotrophin receptors in rat extraocular motoneurons after lesion. Morcuende S, etal., J Comp Neurol. 2011 Aug 15;519(12):2335-52. doi: 10.1002/cne.22630.
26. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
27. Effector immediate-early gene arc in the amygdala plays a critical role in alcoholism. Pandey SC, etal., J Neurosci. 2008 Mar 5;28(10):2589-600. doi: 10.1523/JNEUROSCI.4752-07.2008.
28. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Pease ME, etal., Invest Ophthalmol Vis Sci. 2000 Mar;41(3):764-74.
29. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
30. Colitis elicits differential changes in the expression levels of receptor tyrosine kinase TrkA and TrkB in colonic afferent neurons: a possible involvement of axonal transport. Qiao LY and Grider JR, Pain. 2010 Oct;151(1):117-27. Epub 2010 Jul 16.
31. Mouse MP Annotation Import Pipeline RGD automated import pipeline
32. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
33. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
34. TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice. Sahenk Z, etal., Exp Neurol. 2010 Aug;224(2):495-506. Epub 2010 May 27.
35. Treadmill exercise alleviates impairment of spatial learning ability through enhancing cell proliferation in the streptozotocin-induced Alzheimer's disease rats. Sim YJ J Exerc Rehabil. 2014 Apr 30;10(2):81-8. doi: 10.12965/jer.140102. eCollection 2014 Apr.
36. Tyrosine kinase B protein expression is reduced in the cerebellum of patients with bipolar disorder. Soontornniyomkij B, etal., J Affect Disord. 2011 Oct;133(3):646-54. Epub 2011 May 25.
37. Enhanced hippocampal BDNF/TrkB signaling in response to fear conditioning in an animal model of posttraumatic stress disorder. Takei S, etal., J Psychiatr Res. 2011 Apr;45(4):460-8. Epub 2010 Sep 21.
38. Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. Tauber SC, etal., J Neuropathol Exp Neurol. 2005 Sep;64(9):806-15.
39. Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders. Thompson Ray M, etal., J Psychiatry Neurosci. 2011 May;36(3):195-203.
40. Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities. Wyneken U, etal., Neuroscience. 2001;102(1):65-74.
41. Effects of corticotrophin on pain behavior and BDNF, CRF levels in frontal cortex of rats suffering from chronic pain. Xu HW, etal., Acta Pharmacol Sin. 2000 Jul;21(7):600-4.
42. Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Xu X, etal., Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19126-31. Epub 2010 Oct 18.
43. Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice. Yajima Y, etal., Brain Res. 2002 Dec 27;958(2):338-46.
44. A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Yeo GS, etal., Nat Neurosci. 2004 Nov;7(11):1187-9. Epub 2004 Oct 24.
45. Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. Zocher M, etal., J Neurovirol. 2000 Dec;6(6):462-77.
Additional References at PubMed
PMID:1327010   PMID:1645620   PMID:1751544   PMID:2160854   PMID:2171894   PMID:2555172   PMID:7582115   PMID:7588071   PMID:7746324   PMID:7991545   PMID:8114702   PMID:8187631  
PMID:8221886   PMID:8223273   PMID:8306895   PMID:8402890   PMID:8530078   PMID:8575307   PMID:8662221   PMID:8815902   PMID:8889548   PMID:8898237   PMID:8918886   PMID:8938453  
PMID:8955272   PMID:8978665   PMID:8994044   PMID:9133385   PMID:9141083   PMID:9148911   PMID:9184113   PMID:9232598   PMID:9263033   PMID:9331334   PMID:9364058   PMID:9398452  
PMID:9421165   PMID:9472042   PMID:9640332   PMID:9712667   PMID:9728914   PMID:9728915   PMID:9731539   PMID:9736648   PMID:9736654   PMID:9881298   PMID:9973328   PMID:10207144  
PMID:10349636   PMID:10357931   PMID:10383116   PMID:10395916   PMID:10398684   PMID:10407040   PMID:10491653   PMID:10516311   PMID:10571233   PMID:10588868   PMID:10595510   PMID:10651992  
PMID:10674466   PMID:10699438   PMID:10700561   PMID:10725924   PMID:10767319   PMID:10798407   PMID:10822268   PMID:10842362   PMID:10869838   PMID:10995833   PMID:11023857   PMID:11042159  
PMID:11076861   PMID:11083466   PMID:11090132   PMID:11114734   PMID:11152640   PMID:11217851   PMID:11295244   PMID:11319859   PMID:11356021   PMID:11487640   PMID:11493560   PMID:11498051  
PMID:11516565   PMID:11581159   PMID:11591653   PMID:11681842   PMID:11684666   PMID:11745667   PMID:11754334   PMID:11775072   PMID:11836532   PMID:11850459   PMID:11877382   PMID:11918285  
PMID:12006576   PMID:12070090   PMID:12077195   PMID:12093746   PMID:12122447   PMID:12151767   PMID:12161017   PMID:12196573   PMID:12202482   PMID:12367511   PMID:12388556   PMID:12466851  
PMID:12477932   PMID:12532410   PMID:12552255   PMID:12601381   PMID:12646573   PMID:12654337   PMID:12676531   PMID:12703550   PMID:12774239   PMID:12796784   PMID:12798291   PMID:12810600  
PMID:12900419   PMID:12925599   PMID:12930808   PMID:14507777   PMID:14581459   PMID:14602830   PMID:14603320   PMID:14610273   PMID:14622193   PMID:14625139   PMID:14681479   PMID:14706643  
PMID:14988041   PMID:15013804   PMID:15121188   PMID:15233915   PMID:15297267   PMID:15322547   PMID:15329723   PMID:15329828   PMID:15372074   PMID:15372954   PMID:15376326   PMID:15489334  
PMID:15497153   PMID:15519679   PMID:15530548   PMID:15530873   PMID:15561438   PMID:15598981   PMID:15601948   PMID:15639186   PMID:15647480   PMID:15726425   PMID:15747579   PMID:15765148  
PMID:15781149   PMID:15820690   PMID:15829629   PMID:15829735   PMID:15836427   PMID:16009525   PMID:16037097   PMID:16115204   PMID:16141072   PMID:16141073   PMID:16142215   PMID:16183241  
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PMID:16815329   PMID:16819522   PMID:16837849   PMID:16971523   PMID:17013912   PMID:17038521   PMID:17040478   PMID:17101216   PMID:17101229   PMID:17116228   PMID:17116257   PMID:17183451  
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PMID:17553693   PMID:17584746   PMID:17594599   PMID:17611278   PMID:17616679   PMID:17880937   PMID:17940030   PMID:17940915   PMID:18045880   PMID:18063676   PMID:18086710   PMID:18187310  
PMID:18248898   PMID:18287532   PMID:18287559   PMID:18304484   PMID:18311133   PMID:18322085   PMID:18371392   PMID:18374609   PMID:18385258   PMID:18398849   PMID:18498732   PMID:18498735  
PMID:18511296   PMID:18588860   PMID:18601981   PMID:18620014   PMID:18671735   PMID:18701066   PMID:18752272   PMID:18760367   PMID:18779873   PMID:18832146   PMID:18839409   PMID:18848646  
PMID:18990365   PMID:19020035   PMID:19029029   PMID:19030180   PMID:19036963   PMID:19074010   PMID:19158294   PMID:19179431   PMID:19217934   PMID:19291307   PMID:19322198   PMID:19339612  
PMID:19357131   PMID:19361496   PMID:19403818   PMID:19429046   PMID:19521500   PMID:19523540   PMID:19603519   PMID:19631204   PMID:19675247   PMID:19707543   PMID:19735291   PMID:19741136  
PMID:19755105   PMID:19801649   PMID:19804761   PMID:19805360   PMID:19936227   PMID:20034568   PMID:20064391   PMID:20064392   PMID:20064930   PMID:20091777   PMID:20096094   PMID:20101235  
PMID:20101602   PMID:20133677   PMID:20133810   PMID:20200945   PMID:20213756   PMID:20333308   PMID:20368433   PMID:20407211   PMID:20427667   PMID:20434997   PMID:20442398   PMID:20457670  
PMID:20460112   PMID:20534675   PMID:20600640   PMID:20605779   PMID:20610380   PMID:20610389   PMID:20626560   PMID:20685990   PMID:20739478   PMID:20811452   PMID:20844136   PMID:20932311  
PMID:20947769   PMID:20955473   PMID:21038447   PMID:21047554   PMID:21102451   PMID:21117150   PMID:21192928   PMID:21195749   PMID:21205893   PMID:21220014   PMID:21246648   PMID:21267068  
PMID:21272243   PMID:21300867   PMID:21304518   PMID:21339379   PMID:21364532   PMID:21414899   PMID:21444756   PMID:21505263   PMID:21510873   PMID:21543603   PMID:21543608   PMID:21555574  
PMID:21562748   PMID:21574998   PMID:21666748   PMID:21677750   PMID:21681751   PMID:21715628   PMID:21734270   PMID:21737823   PMID:21816949   PMID:21826472   PMID:21849472   PMID:21865582  
PMID:21873635   PMID:21945863   PMID:21949401   PMID:22028026   PMID:22028443   PMID:22048155   PMID:22083603   PMID:22087873   PMID:22098391   PMID:22103411   PMID:22196735   PMID:22219288  
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PMID:22396798   PMID:22442142   PMID:22492034   PMID:22514301   PMID:22535263   PMID:22573669   PMID:22586092   PMID:22586713   PMID:22734669   PMID:22761934   PMID:22776425   PMID:22840395  
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PMID:23884949   PMID:23912236   PMID:23928917   PMID:23959707   PMID:23977241   PMID:24027274   PMID:24035762   PMID:24043773   PMID:24069373   PMID:24070857   PMID:24086766   PMID:24154525  
PMID:24194600   PMID:24198358   PMID:24221086   PMID:24236179   PMID:24312242   PMID:24327964   PMID:24355921   PMID:24357327   PMID:24360544   PMID:24369067   PMID:24386206   PMID:24403258  
PMID:24453327   PMID:24478370   PMID:24498100   PMID:24516396   PMID:24523535   PMID:24569481   PMID:24583017   PMID:24613359   PMID:24619096   PMID:24685135   PMID:24714156   PMID:24853771  
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Genomics

Comparative Map Data
Ntrk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,954,363 - 59,281,782 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,954,383 - 59,281,784 (+)EnsemblGRCm39 Ensembl
GRCm381358,806,472 - 59,133,970 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,806,569 - 59,133,970 (+)EnsemblGRCm38mm10GRCm38
MGSCv371358,907,957 - 59,231,337 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361358,816,219 - 59,139,599 (+)NCBIMGSCv36mm8
Celera1359,869,829 - 60,184,466 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1331.2NCBI
NTRK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38984,668,522 - 85,027,054 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl984,668,375 - 85,095,751 (+)EnsemblGRCh38hg38GRCh38
GRCh37987,283,437 - 87,641,969 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36986,473,286 - 86,828,325 (+)NCBINCBI36Build 36hg18NCBI36
Build 34984,514,246 - 84,866,963NCBI
Celera957,854,390 - 58,209,019 (+)NCBICelera
Cytogenetic Map9q21.33NCBI
HuRef957,108,647 - 57,463,914 (+)NCBIHuRef
CHM1_1987,429,973 - 87,785,074 (+)NCBICHM1_1
T2T-CHM13v2.0996,818,888 - 97,177,857 (+)NCBIT2T-CHM13v2.0
Ntrk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2175,558,992 - 5,870,299 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl175,559,043 - 5,869,136 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx175,584,315 - 5,894,662 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0177,120,448 - 7,429,363 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0175,580,732 - 5,891,094 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0175,934,651 - 6,245,778 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl175,933,729 - 6,244,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0178,156,432 - 8,464,522 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41711,494,463 - 11,811,654 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11711,494,462 - 11,811,645 (-)NCBI
Celera175,673,895 - 6,828,108 (-)NCBICelera
Cytogenetic Map17p14NCBI
Ntrk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554322,288,898 - 2,630,878 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554322,284,283 - 2,629,631 (-)NCBIChiLan1.0ChiLan1.0
NTRK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1983,835,183 - 84,380,018 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0939,663,986 - 40,208,770 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1984,022,677 - 84,378,307 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl984,021,837 - 84,372,678 (+)Ensemblpanpan1.1panPan2
NTRK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1174,447,927 - 74,777,910 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl174,449,060 - 74,777,032 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha175,211,260 - 75,538,451 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0174,754,263 - 75,081,259 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl174,755,372 - 75,083,341 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1174,562,918 - 74,890,457 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0174,331,860 - 74,658,907 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0175,035,216 - 75,362,564 (-)NCBIUU_Cfam_GSD_1.0
Ntrk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947121,116,646 - 121,472,444 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936680267,596 - 615,928 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936680267,850 - 621,467 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NTRK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1030,033,405 - 30,429,882 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11030,030,050 - 30,429,938 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21034,211,939 - 34,350,822 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NTRK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11295,477,612 - 95,836,734 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1295,479,447 - 95,620,364 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603883,830,767 - 84,200,895 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ntrk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248098,276,951 - 8,616,765 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248098,274,736 - 8,622,287 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ntrk2
11996 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3904
Count of miRNA genes:973
Interacting mature miRNAs:1430
Transcripts:ENSMUST00000079828, ENSMUST00000109838
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse

Markers in Region
AI848316  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381359,129,657 - 59,129,737UniSTSGRCm38
MGSCv371359,231,018 - 59,231,098UniSTSGRCm37
Celera1360,184,147 - 60,184,227UniSTS
Cytogenetic Map13B1-B2UniSTS
Whitehead/MRC_RH13605.61UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
cM Map1336.0UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
cM Map1336.0UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS
Ntrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B1-B2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001426309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB377224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB377225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02135590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG695150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP757570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY125925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY713295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01018215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01171542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ098737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX238945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC855567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF982303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M33385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X17647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y12067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000079828   ⟹   ENSMUSP00000078757
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,955,511 - 59,281,784 (+)Ensembl
GRCm38.p6 Ensembl1358,807,697 - 59,133,970 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109838   ⟹   ENSMUSP00000105464
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,956,095 - 59,084,841 (+)Ensembl
GRCm38.p6 Ensembl1358,808,281 - 58,937,027 (+)Ensembl
RefSeq Acc Id: ENSMUST00000223636   ⟹   ENSMUSP00000152907
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1359,019,549 - 59,133,963 (+)Ensembl
GRCm38.p6 Ensembl1358,871,735 - 58,986,149 (+)Ensembl
RefSeq Acc Id: ENSMUST00000224259   ⟹   ENSMUSP00000153270
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,954,453 - 59,080,934 (+)Ensembl
GRCm38.p6 Ensembl1358,806,639 - 58,933,120 (+)Ensembl
RefSeq Acc Id: ENSMUST00000224402   ⟹   ENSMUSP00000153333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,955,692 - 59,026,563 (+)Ensembl
GRCm38.p6 Ensembl1358,807,878 - 58,878,749 (+)Ensembl
RefSeq Acc Id: ENSMUST00000225119
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,954,404 - 58,954,856 (+)Ensembl
GRCm38.p6 Ensembl1358,806,590 - 58,807,042 (+)Ensembl
RefSeq Acc Id: ENSMUST00000225488   ⟹   ENSMUSP00000153553
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,954,383 - 59,277,779 (+)Ensembl
GRCm38.p6 Ensembl1358,806,569 - 59,129,965 (+)Ensembl
RefSeq Acc Id: ENSMUST00000225583   ⟹   ENSMUSP00000153337
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,956,505 - 59,036,293 (+)Ensembl
GRCm38.p6 Ensembl1358,808,691 - 58,888,479 (+)Ensembl
RefSeq Acc Id: ENSMUST00000225950   ⟹   ENSMUSP00000153152
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,956,505 - 59,036,293 (+)Ensembl
GRCm38.p6 Ensembl1358,808,691 - 58,888,479 (+)Ensembl
RefSeq Acc Id: ENSMUST00000226021
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1358,983,629 - 58,987,092 (+)Ensembl
GRCm38.p6 Ensembl1358,835,815 - 58,839,278 (+)Ensembl
RefSeq Acc Id: NM_001025074   ⟹   NP_001020245
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,955,511 - 59,281,780 (+)NCBI
GRCm381358,807,697 - 59,133,970 (+)NCBI
MGSCv371358,907,957 - 59,231,337 (+)RGD
Celera1359,869,802 - 60,188,461 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001282961   ⟹   NP_001269890
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,393 - 59,281,780 (+)NCBI
GRCm381358,806,569 - 59,133,970 (+)NCBI
Celera1359,869,802 - 60,188,461 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001426304   ⟹   NP_001413233
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,393 - 59,084,841 (+)NCBI
RefSeq Acc Id: NM_001426306   ⟹   NP_001413235
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,955,511 - 59,084,841 (+)NCBI
RefSeq Acc Id: NM_001426307   ⟹   NP_001413236
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,956,083 - 59,084,841 (+)NCBI
RefSeq Acc Id: NM_001426308   ⟹   NP_001413237
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,393 - 59,143,846 (+)NCBI
RefSeq Acc Id: NM_001426309   ⟹   NP_001413238
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,955,511 - 59,143,846 (+)NCBI
RefSeq Acc Id: NM_008745   ⟹   NP_032771
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,393 - 59,084,841 (+)NCBI
GRCm381358,806,569 - 58,937,031 (+)NCBI
MGSCv371358,907,957 - 59,231,337 (+)RGD
Celera1359,869,802 - 60,188,461 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517149   ⟹   XP_006517212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,654 - 59,281,782 (+)NCBI
GRCm381358,806,844 - 59,133,968 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517151   ⟹   XP_006517214
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,955,317 - 59,035,230 (+)NCBI
GRCm381358,807,608 - 58,893,403 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247189   ⟹   XP_030103049
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,654 - 59,084,841 (+)NCBI
GRCm381358,806,885 - 58,937,027 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157911   ⟹   XP_036013804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391358,954,363 - 59,035,230 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001020245 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269890 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413233 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413235 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413236 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413237 (Get FASTA)   NCBI Sequence Viewer  
  NP_001413238 (Get FASTA)   NCBI Sequence Viewer  
  NP_032771 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517212 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517214 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103049 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013804 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40482 (Get FASTA)   NCBI Sequence Viewer  
  AAH52014 (Get FASTA)   NCBI Sequence Viewer  
  AGR50958 (Get FASTA)   NCBI Sequence Viewer  
  AHL58822 (Get FASTA)   NCBI Sequence Viewer  
  BAB31412 (Get FASTA)   NCBI Sequence Viewer  
  BAE27880 (Get FASTA)   NCBI Sequence Viewer  
  BAE27914 (Get FASTA)   NCBI Sequence Viewer  
  BAE36012 (Get FASTA)   NCBI Sequence Viewer  
  BAG69574 (Get FASTA)   NCBI Sequence Viewer  
  BAG69575 (Get FASTA)   NCBI Sequence Viewer  
  CAA35636 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000078757
  ENSMUSP00000078757.6
  ENSMUSP00000105464.3
  ENSMUSP00000152907.2
  ENSMUSP00000153152.2
  ENSMUSP00000153270
  ENSMUSP00000153270.2
  ENSMUSP00000153333
  ENSMUSP00000153333.2
  ENSMUSP00000153337.2
  ENSMUSP00000153553
  ENSMUSP00000153553.2
GenBank Protein P15209 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032771   ⟸   NM_008745
- Peptide Label: isoform b precursor
- UniProtKB: Q3UHE3 (UniProtKB/TrEMBL),   A0A286YDA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020245   ⟸   NM_001025074
- Peptide Label: isoform a precursor
- UniProtKB: Q80WU0 (UniProtKB/Swiss-Prot),   Q3TUF9 (UniProtKB/Swiss-Prot),   Q91XJ9 (UniProtKB/Swiss-Prot),   P15209 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001269890   ⟸   NM_001282961
- Peptide Label: isoform a precursor
- UniProtKB: Q80WU0 (UniProtKB/Swiss-Prot),   Q3TUF9 (UniProtKB/Swiss-Prot),   Q91XJ9 (UniProtKB/Swiss-Prot),   P15209 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517212   ⟸   XM_006517149
- Peptide Label: isoform X1
- UniProtKB: Q80WU0 (UniProtKB/Swiss-Prot),   Q3TUF9 (UniProtKB/Swiss-Prot),   Q91XJ9 (UniProtKB/Swiss-Prot),   P15209 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517214   ⟸   XM_006517151
- Peptide Label: isoform X3
- UniProtKB: A0A286YDA3 (UniProtKB/TrEMBL),   A0A286YDA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030103049   ⟸   XM_030247189
- Peptide Label: isoform X4
- UniProtKB: Q3UHE3 (UniProtKB/TrEMBL),   A0A286YDA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000152907   ⟸   ENSMUST00000223636
RefSeq Acc Id: ENSMUSP00000078757   ⟸   ENSMUST00000079828
RefSeq Acc Id: ENSMUSP00000153152   ⟸   ENSMUST00000225950
RefSeq Acc Id: ENSMUSP00000153553   ⟸   ENSMUST00000225488
RefSeq Acc Id: ENSMUSP00000153337   ⟸   ENSMUST00000225583
RefSeq Acc Id: ENSMUSP00000153333   ⟸   ENSMUST00000224402
RefSeq Acc Id: ENSMUSP00000153270   ⟸   ENSMUST00000224259
RefSeq Acc Id: ENSMUSP00000105464   ⟸   ENSMUST00000109838
RefSeq Acc Id: XP_036013804   ⟸   XM_036157911
- Peptide Label: isoform X3
- UniProtKB: A0A286YDA3 (UniProtKB/TrEMBL),   A0A286YDA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413237   ⟸   NM_001426308
- Peptide Label: isoform c precursor
- UniProtKB: A0A286YDA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413233   ⟸   NM_001426304
- Peptide Label: isoform b precursor
- UniProtKB: A0A286YDA0 (UniProtKB/TrEMBL),   Q3UHE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413238   ⟸   NM_001426309
- Peptide Label: isoform c precursor
- UniProtKB: A0A286YDA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413235   ⟸   NM_001426306
- Peptide Label: isoform b precursor
- UniProtKB: A0A286YDA0 (UniProtKB/TrEMBL),   Q3UHE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001413236   ⟸   NM_001426307
- Peptide Label: isoform b precursor
- UniProtKB: A0A286YDA0 (UniProtKB/TrEMBL),   Q3UHE3 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Ig-like C2-type   LRRCT   LRRNT   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P15209-F1-model_v2 AlphaFold P15209 1-821 view protein structure

Promoters
RGD ID:8680542
Promoter ID:EPDNEW_M18302
Type:initiation region
Name:Ntrk2_2
Description:Mus musculus neurotrophic tyrosine kinase, receptor, type 2 ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18303  EPDNEW_M18304  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381358,806,612 - 58,806,672EPDNEW
RGD ID:8680544
Promoter ID:EPDNEW_M18303
Type:initiation region
Name:Ntrk2_1
Description:Mus musculus neurotrophic tyrosine kinase, receptor, type 2 ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18302  EPDNEW_M18304  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381358,807,871 - 58,807,931EPDNEW
RGD ID:8680546
Promoter ID:EPDNEW_M18304
Type:initiation region
Name:Ntrk2_3
Description:Mus musculus neurotrophic tyrosine kinase, receptor, type 2 ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18302  EPDNEW_M18303  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381358,808,277 - 58,808,337EPDNEW
RGD ID:6824210
Promoter ID:MM_KWN:14333
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_008745,   UC007QUI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361358,907,851 - 58,908,351 (+)MPROMDB
RGD ID:6824207
Promoter ID:MM_KWN:14334
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000078541,   ENSMUST00000079828,   ENSMUST00000109838,   ENSMUST00000109839,   ENSMUST00000109840,   UC007QUK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361358,909,051 - 58,910,052 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97384 AgrOrtholog
Ensembl Genes ENSMUSG00000055254 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000079828 ENTREZGENE
  ENSMUST00000079828.7 UniProtKB/Swiss-Prot
  ENSMUST00000109838.10 UniProtKB/Swiss-Prot
  ENSMUST00000223636.2 UniProtKB/TrEMBL
  ENSMUST00000224259 ENTREZGENE
  ENSMUST00000224259.2 UniProtKB/Swiss-Prot
  ENSMUST00000224402 ENTREZGENE
  ENSMUST00000224402.2 UniProtKB/TrEMBL
  ENSMUST00000225488 ENTREZGENE
  ENSMUST00000225488.2 UniProtKB/Swiss-Prot
  ENSMUST00000225583.2 UniProtKB/TrEMBL
  ENSMUST00000225950.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTRK_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kin_neurotrophic_rcpt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_NGF_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_rcpt_2_CS UniProtKB/Swiss-Prot
KEGG Report mmu:18212 UniProtKB/Swiss-Prot
MGD MGI:97384 ENTREZGENE
NCBI Gene 18212 ENTREZGENE
PANTHER BDNF/NT-3 GROWTH FACTORS RECEPTOR UniProtKB/Swiss-Prot
  CONTACTIN 5 UniProtKB/TrEMBL
  CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  HEMICENTIN-2-RELATED UniProtKB/TrEMBL
  IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN Y54G2A.25 UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot
  TPKR_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB NTRK2 RGD
PhenoGen Ntrk2 PhenoGen
PRINTS NTKRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTKRECEPTOR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYRKINASE UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_II UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot
UniProt A0A286YCB7_MOUSE UniProtKB/TrEMBL
  A0A286YCV8_MOUSE UniProtKB/TrEMBL
  A0A286YDA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A286YDA3 ENTREZGENE, UniProtKB/TrEMBL
  B5BQV3_MOUSE UniProtKB/TrEMBL
  B5BQV4_MOUSE UniProtKB/TrEMBL
  NTRK2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TUF9 ENTREZGENE
  Q3UHE3 ENTREZGENE, UniProtKB/TrEMBL
  Q80WU0 ENTREZGENE
  Q91XJ9 ENTREZGENE
  S5N1F5_MOUSE UniProtKB/TrEMBL
  W8R8Q6_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TUF9 UniProtKB/Swiss-Prot
  Q80WU0 UniProtKB/Swiss-Prot
  Q91XJ9 UniProtKB/Swiss-Prot