Ngf (nerve growth factor) - Rat Genome Database

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Gene: Ngf (nerve growth factor) Mus musculus
Analyze
Symbol: Ngf
Name: nerve growth factor
RGD ID: 10978
MGI Page MGI
Description: Enables transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including circadian rhythm; neurotrophin TRK receptor signaling pathway; and positive regulation of intracellular signal transduction. Acts upstream of or within several processes, including cell surface receptor signaling pathway; positive regulation of cell projection organization; and positive regulation of protein modification process. Located in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Used to study hereditary sensory and autonomic neuropathy type 5. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; end stage renal disease; hereditary sensory and autonomic neuropathy type 5; interstitial cystitis; and opiate dependence (multiple). Orthologous to human NGF (nerve growth factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-nerve growth factor; beta-NGF; nerve growth factor, beta; Ngfb
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393102,377,235 - 102,428,329 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3102,377,235 - 102,428,329 (+)EnsemblGRCm39 Ensembl
GRCm383102,469,919 - 102,521,013 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3102,469,919 - 102,521,013 (+)EnsemblGRCm38mm10GRCm38
MGSCv373102,273,851 - 102,324,936 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363102,598,989 - 102,650,066 (+)NCBIMGSCv36mm8
Celera3104,674,123 - 104,724,621 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (IMP)
alcohol dependence  (ISO)
alcohol use disorder  (IEP,ISO)
Alcohol Withdrawal Delirium  (ISO)
alcohol withdrawal syndrome  (ISO)
Alcohol-Related Disorders  (IEP,ISO)
Alcoholic Intoxication  (IEP,ISO)
Alzheimer's disease  (ISO)
amnestic disorder  (ISO)
asthma  (IEP,ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
bacterial meningitis  (ISO)
bipolar disorder  (ISO)
bladder disease  (IMP)
bladder neck obstruction  (ISO)
borna disease  (ISO)
Bronchial Hyperreactivity  (ISO)
Burns  (ISO)
cannabis abuse  (ISO)
Charcot-Marie-Tooth disease  (ISO)
chronic asthma  (ISO)
chronic kidney disease  (ISO)
Chronic Pancreatitis  (ISO)
chronic ulcer of skin  (ISO)
cocaine dependence  (ISO)
Cocaine-Related Disorders  (ISO)
Congenital Pain Insensitivity  (ISO)
corneal ulcer  (ISO)
coronary artery disease  (ISO)
cryptorchidism  (ISO)
cystitis  (IDA,IEP,ISO)
degenerative disc disease  (ISO)
depressive disorder  (ISO)
diabetic encephalopathy  (IDA,IMP)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
end stage renal disease  (ISO)
epilepsy with generalized tonic-clonic seizures  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Diabetes Mellitus  (IMP,ISO)
genetic disease  (ISO)
glaucoma  (ISO)
glomerulonephritis  (ISO)
hereditary sensory and autonomic neuropathy type 5  (ISO)
hereditary sensory neuropathy  (ISO)
heroin dependence  (ISO)
Hyperalgesia  (IMP,ISO)
hyperhomocysteinemia  (ISO)
Hyperkinesis  (ISO)
hypertension  (ISO)
hypothyroidism  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (ISO)
interstitial cystitis  (IDA,ISO)
interstitial lung disease  (ISO)
interstitial nephritis  (ISO)
Lewy body dementia  (ISO)
Lung Injury  (IEP,ISO)
malignant mesothelioma  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (ISO)
morphine dependence  (ISO)
myocardial infarction  (ISO)
myofascial pain syndrome  (ISO)
Nerve Degeneration  (ISO)
nervous system disease  (ISO)
Neurobehavioral Manifestations  (ISO)
neurodegenerative disease  (ISO)
neurogenic bladder  (ISO)
Neurogenic Inflammation  (ISO)
nicotine dependence  (IEP)
obstructive sleep apnea  (ISO)
opiate dependence  (IEP,ISO)
opiate withdrawal syndrome  (ISO)
Optic Nerve Injuries  (ISO)
osteoarthritis  (ISO)
overactive bladder syndrome  (IEP,ISO)
Pain  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
Peripheral Nerve Injuries  (ISO)
peripheral nervous system disease  (ISO)
Postoperative Cognitive Dysfunction  (IEP,ISO)
Prenatal Exposure Delayed Effects  (ISO)
pulmonary fibrosis  (ISO)
pulmonary sarcoidosis  (ISO)
RASopathy  (ISO)
respiratory syncytial virus infectious disease  (ISO)
retinal vascular disease  (IMP)
retinitis pigmentosa  (ISO)
Retrograde Degeneration  (ISO)
rhinitis  (ISO)
Rib Fractures  (ISO)
Rotator Cuff Injuries  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (IDA,IEP)
sensorineural hearing loss  (ISO)
separation anxiety disorder  (ISO)
Skeletal Muscle Injuries  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
stress-related disorder  (ISO)
Stroke  (ISO)
systemic scleroderma  (ISO)
traumatic brain injury  (ISO)
withdrawal disorder  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-taxifolin  (ISO)
(R)-noradrenaline  (ISO)
(S)-amphetamine  (ISO)
(S)-nicotine  (EXP,ISO)
1-chloro-2,4,6-trinitrobenzene  (EXP)
13,14-dihydro-Delta(12)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP)
4-methylcatechol  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
agathisflavone  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
Asiaticoside  (ISO)
ATP  (ISO)
atrazine  (ISO)
azamethiphos  (ISO)
Bay-K-8644  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (ISO)
beta-D-glucosamine  (ISO)
bicuculline  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromocriptine  (EXP)
bucladesine  (ISO)
C60 fullerene  (ISO)
cabergoline  (EXP)
cadmium acetate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
Calcimycin  (ISO)
calcitriol  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
calmidazolium  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP,ISO)
carbon monoxide  (ISO)
carmustine  (ISO)
carrageenan  (ISO)
celecoxib  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (EXP)
chrysin  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
colistin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
Cuprizon  (ISO)
cyanocob(III)alamin  (ISO)
cycloheximide  (EXP)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
D-glucose  (ISO)
dapagliflozin  (ISO)
dexamethasone  (ISO)
diazinon  (EXP,ISO)
dibutyl phthalate  (ISO)
dieldrin  (EXP,ISO)
dihydrolipoic acid  (EXP)
dioxygen  (ISO)
disodium selenite  (EXP)
dopaminechrome (enol form)  (ISO)
doxorubicin  (ISO)
ebselen  (EXP)
echinacoside  (ISO)
edaravone  (ISO)
endosulfan  (ISO)
epalrestat  (ISO)
epinastine  (EXP)
epothilone B  (ISO)
etacrynic acid  (EXP)
ethanol  (EXP,ISO)
ethylparaben  (ISO)
everolimus  (ISO)
Evodiamine  (EXP)
excitatory amino acid agonist  (ISO)
fenthion  (EXP)
ferrostatin-1  (ISO)
fluphenazine  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (EXP)
formononetin  (ISO)
fructose  (ISO)
Fusarenone X  (EXP)
galanthamine  (ISO)
galanthamine Trifluoroacetic acid  (ISO)
Geniposide pentaacetate  (ISO)
genistein  (ISO)
gentamycin  (ISO)
ginsenoside Rd  (EXP)
ginsenoside Re  (EXP)
glucose  (ISO)
glutathione  (EXP,ISO)
glutathione disulfide  (EXP)
glycidol  (ISO)
Goe 6976  (ISO)
heptachlor  (ISO)
heroin  (ISO)
histamine  (ISO)
hydrogen peroxide  (ISO)
imiquimod  (EXP)
indometacin  (ISO)
inulin  (EXP)
isoprenaline  (ISO)
ketamine  (ISO)
ketotifen  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP,ISO)
lidocaine  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
LY294002  (EXP,ISO)
malathion  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mangiferin  (ISO)
masoprocol  (ISO)
mepyramine  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP,ISO)
Methanandamide  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
microcystin-LR  (EXP)
mithramycin  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
naproxen  (ISO)
nickel atom  (EXP,ISO)
nicotine  (EXP,ISO)
nifedipine  (ISO)
nimesulide  (ISO)
nitrates  (ISO)
nitric oxide  (ISO)
nocodazole  (ISO)
Nonylphenol  (ISO)
O-acetyl-L-carnitine  (ISO)
okadaic acid  (ISO)
oxidopamine  (EXP)
ozone  (EXP,ISO)
paclitaxel  (ISO)
panaxydol  (ISO)
paracetamol  (EXP,ISO)
parathion-methyl  (ISO)
PD-166866  (ISO)
pentane-2,3-dione  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
pergolide  (EXP)
permethrin  (ISO)
peroxynitrous acid  (ISO)
phenethyl caffeate  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pirinixic acid  (EXP)
potassium atom  (ISO)
procymidone  (ISO)
progesterone  (ISO)
promethazine  (ISO)
propofol  (ISO)
propranolol  (ISO)
prostaglandin E2  (ISO)
Ptaquiloside  (EXP)
Pyridostigmine bromide  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
ranitidine  (ISO)
reactive oxygen species  (EXP,ISO)
reserpine  (ISO)
resveratrol  (ISO)
rofecoxib  (ISO)
roflumilast  (ISO)
rotenone  (ISO)
rottlerin  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
Salidroside  (ISO)
salubrinal  (EXP)
SB 203580  (ISO)
scopolamine  (EXP,ISO)
SKF 38393  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
sorbinil  (ISO)
staurosporine  (EXP,ISO)
streptozocin  (ISO)
sulforaphane  (ISO)
sumatriptan  (ISO)
tacrolimus hydrate  (ISO)
taurine  (ISO)
temozolomide  (ISO)
terbutaline  (ISO)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (EXP)
thimerosal  (ISO)
thiopental  (ISO)
thymoquinone  (ISO)
titanium dioxide  (EXP)
toluene  (EXP)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triprolidine  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
udenafil  (ISO)
valproic acid  (EXP)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vindesine  (ISO)
wortmannin  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult locomotory behavior  (ISO)
axon extension  (IMP)
cell population proliferation  (ISO)
cell proliferation in forebrain  (ISO)
cell surface receptor protein tyrosine kinase signaling pathway  (IBA)
circadian rhythm  (IEP)
extrinsic apoptotic signaling pathway in absence of ligand  (IDA)
extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
memory  (ISO)
modulation of chemical synaptic transmission  (IBA)
negative regulation of neuron apoptotic process  (IBA,IGI,ISO)
negative regulation of type B pancreatic cell apoptotic process  (ISO)
nerve development  (IBA)
nerve growth factor signaling pathway  (IBA,IDA,IGI)
neuron apoptotic process  (IGI,IMP,ISO)
neuron differentiation  (ISO)
neuron projection development  (IDA,ISO)
neuron projection morphogenesis  (IBA,ISO)
neurotrophin TRK receptor signaling pathway  (IDA)
peripheral nervous system development  (IMP)
positive regulation of axon extension  (IDA,IMP)
positive regulation of cell growth  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of collateral sprouting  (IDA)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IDA,ISO)
positive regulation of gene expression  (IGI,ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of neuron maturation  (IDA,IGI)
positive regulation of neuron projection development  (IDA,IGI)
positive regulation of neurotrophin TRK receptor signaling pathway  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IDA)
positive regulation of protein autophosphorylation  (ISO)
positive regulation of protein phosphorylation  (IDA,ISO)
positive regulation of protein ubiquitination  (IDA)
positive regulation of Ras protein signal transduction  (IDA)
positive regulation of stem cell proliferation  (ISO)
protein phosphorylation  (IDA)
regulation of neuron differentiation  (IDA)
regulation of neurotransmitter secretion  (IGI)
regulation of release of sequestered calcium ion into cytosol  (IGI)
response to electrical stimulus  (ISO)
response to glucocorticoid  (ISO)
response to lipopolysaccharide  (ISO)
response to mechanical stimulus  (ISO)
response to nicotine  (ISO)
response to ozone  (ISO)
response to peptide hormone  (ISO)
response to xenobiotic stimulus  (ISO)
sensory perception of hot stimulus  (ISO)
sensory perception of pain  (IMP)
spermatogenesis  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cholinergic neuron morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal gait  (IAGP)
abnormal hair growth  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal object recognition memory  (IAGP)
abnormal pain threshold  (IAGP)
abnormal pericyte morphology  (IAGP)
abnormal sciatic nerve morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal skin sensory neuron innervation pattern  (IAGP)
abnormal striatum morphology  (IAGP)
abnormal sympathetic ganglion morphology  (IAGP)
abnormal touch/ nociception  (IAGP)
abnormal vascular endothelial cell morphology  (IAGP)
abnormal vascular endothelial cell physiology  (IAGP)
absent superior cervical ganglion  (IAGP)
blepharoptosis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased cardiac muscle contractility  (IAGP)
delayed eyelid opening  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated heart left ventricle  (IAGP)
dilated heart right ventricle  (IAGP)
dorsal root ganglion hypoplasia  (IAGP)
edema  (IAGP)
hypoalgesia  (IAGP)
impaired spatial learning  (IAGP)
increased chemical nociceptive threshold  (IAGP)
increased thermal nociceptive threshold  (IAGP)
increased vascular permeability  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
small superior cervical ganglion  (IAGP)
thin myocardium  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Epicatechin blocks pro-nerve growth factor (proNGF)-mediated retinal neurodegeneration via inhibition of p75 neurotrophin receptor expression in a rat model of diabetes . Al-Gayyar MM, etal., Diabetologia. 2011 Mar;54(3):669-80. Epub 2010 Dec 7.
2. Compromise of cortical proNGF maturation causes selective retrograde atrophy in cholinergic nucleus basalis neurons. Allard S, etal., Neurobiol Aging. 2018 Jul;67:10-20. doi: 10.1016/j.neurobiolaging.2018.03.002. Epub 2018 Mar 9.
3. Changes in human plasma nerve growth factor level after chronic alcohol consumption and withdrawal. Aloe L, etal., Alcohol Clin Exp Res. 1996 May;20(3):462-5. doi: 10.1111/j.1530-0277.1996.tb01076.x.
4. Reduced serum concentrations of nerve growth factor, but not brain-derived neurotrophic factor, in chronic cannabis abusers. Angelucci F, etal., Eur Neuropsychopharmacol. 2008 Dec;18(12):882-7. doi: 10.1016/j.euroneuro.2008.07.008. Epub 2008 Sep 6.
5. Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. Angelucci F, etal., J Psychopharmacol. 2007 Nov;21(8):820-5. doi: 10.1177/0269881107078491. Epub 2007 Aug 22.
6. Prenatal ethanol effects on NGF level, NPY and ChAT immunoreactivity in mouse entorhinal cortex: a preliminary study. Angelucci F, etal., Neurotoxicol Teratol. 1999 Jul-Aug;21(4):415-25. doi: 10.1016/s0892-0362(99)00005-7.
7. Nerve growth factor and its monocyte receptors are affected in kidney disease. Antonucci MT, etal., Nephron Clin Pract. 2009;111(1):c21-8. doi: 10.1159/000178819. Epub 2008 Dec 9.
8. Limonene, a food additive, and its active metabolite perillyl alcohol improve regeneration and attenuate neuropathic pain after peripheral nerve injury: Evidence for IL-1β, TNF-α, GAP, NGF and ERK involvement. Araújo-Filho HG, etal., Int Immunopharmacol. 2020 Sep;86:106766. doi: 10.1016/j.intimp.2020.106766. Epub 2020 Jul 8.
9. Evaluation of the brain-derived neurotrophic factor, nerve growth factor and memory in adult rats survivors of the neonatal meningitis by Streptococcus agalactiae. Barichello T, etal., Brain Res Bull. 2013 Mar;92:56-9. doi: 10.1016/j.brainresbull.2012.05.014. Epub 2012 Jun 7.
10. Endothelin ETA receptor antagonist reverses naloxone-precipitated opioid withdrawal in mice. Bhalla S, etal., Can J Physiol Pharmacol. 2015 Nov;93(11):935-44. doi: 10.1139/cjpp-2015-0022. Epub 2015 Apr 28.
11. Upregulation of nerve growth factor in central amygdala increases sensitivity to opioid reward. Bie B, etal., Neuropsychopharmacology. 2012 Dec;37(13):2780-8. doi: 10.1038/npp.2012.144. Epub 2012 Aug 8.
12. Intravesical Escherichia coli lipopolysaccharide stimulates an increase in bladder nerve growth factor. Bjorling DE, etal., BJU Int. 2001 May;87(7):697-702.
13. Functional characterization of a chronic cyclophosphamide-induced overactive bladder model in mice. Boudes M, etal., Neurourol Urodyn. 2011 Nov;30(8):1659-65. doi: 10.1002/nau.21180. Epub 2011 Jun 29.
14. Expression of nerve growth factor carried by pseudotyped lentivirus improves neuron survival and cognitive functional recovery of post-ischemia in rats. Cao JY, etal., CNS Neurosci Ther. 2018 Jun;24(6):508-518. doi: 10.1111/cns.12818. Epub 2018 Feb 6.
15. NGF and BDNF long-term variations in the thyroid, testis and adrenal glands of a mouse model of fetal alcohol spectrum disorders. Ceccanti M, etal., Ann Ist Super Sanita. 2013;49(4):383-90. doi: 10.4415/ANN_13_04_11.
16. NGF, BDNF, leptin, and mast cells in human coronary atherosclerosis and metabolic syndrome. Chaldakov GN, etal., Arch Physiol Biochem. 2001 Oct;109(4):357-60.
17. Nerve growth factor levels and mast cell distribution in human coronary atherosclerosis. Chaldakov GN, etal., Atherosclerosis. 2001 Nov;159(1):57-66.
18. Combination therapy with intranasal NGF and electroacupuncture enhanced cell proliferation and survival in rats after stroke. Cheng S, etal., Neurol Res. 2008 Dec 5.
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PMID:17417650   PMID:17488777   PMID:17553423   PMID:17594942   PMID:17653039   PMID:17724343   PMID:17881125   PMID:18006062   PMID:18052984   PMID:18087045   PMID:18162309   PMID:18230652  
PMID:18323418   PMID:18329889   PMID:18349525   PMID:18367547   PMID:18498735   PMID:18596692   PMID:18635195   PMID:18657279   PMID:18709654   PMID:18725298   PMID:18774569   PMID:19029245  
PMID:19036963   PMID:19170059   PMID:19193386   PMID:19319189   PMID:19334503   PMID:19342646   PMID:19357131   PMID:19376199   PMID:19389705   PMID:19444944   PMID:19515925   PMID:19728147  
PMID:19755105   PMID:19816194   PMID:19844589   PMID:19893045   PMID:20018664   PMID:20032263   PMID:20036257   PMID:20045424   PMID:20350782   PMID:20449688   PMID:20507613   PMID:20572009  
PMID:20680101   PMID:20696380   PMID:20736176   PMID:21048026   PMID:21085186   PMID:21145972   PMID:21151121   PMID:21165786   PMID:21267068   PMID:21339331   PMID:21385399   PMID:21529369  
PMID:21541365   PMID:21677750   PMID:21816277   PMID:21816457   PMID:21818348   PMID:21873635   PMID:22031887   PMID:22098391   PMID:22168511   PMID:22187379   PMID:22318233   PMID:22503986  
PMID:22520925   PMID:22621370   PMID:22682244   PMID:22700375   PMID:22808101   PMID:22903500   PMID:22906231   PMID:22999926   PMID:23015435   PMID:23091165   PMID:23100411   PMID:23224557  
PMID:23322532   PMID:23426701   PMID:23462468   PMID:23466052   PMID:23538417   PMID:23538529   PMID:23562608   PMID:23623989   PMID:23633509   PMID:23785138   PMID:23825664   PMID:23831350  
PMID:23934089   PMID:23989259   PMID:24006456   PMID:24040063   PMID:24139045   PMID:24154525   PMID:24173031   PMID:24265601   PMID:24270184   PMID:24338202   PMID:24438745   PMID:24574008  
PMID:24631295   PMID:24733831   PMID:24752460   PMID:24760869   PMID:24787014   PMID:24811380   PMID:24908487   PMID:24937592   PMID:24952961   PMID:25049196   PMID:25088915   PMID:25211588  
PMID:25231981   PMID:25286822   PMID:25397406   PMID:25410786   PMID:25460199   PMID:25496838   PMID:25542970   PMID:25647301   PMID:25650182   PMID:25734767   PMID:26066836   PMID:26073142  
PMID:26347141   PMID:26418744   PMID:26631553   PMID:26683342   PMID:27076121   PMID:27306411   PMID:27342083   PMID:27424144   PMID:27437725   PMID:27493098   PMID:27568565   PMID:27635406  
PMID:27655914   PMID:27825441   PMID:27997532   PMID:28079757   PMID:28232789   PMID:28416686   PMID:28453662   PMID:28542147   PMID:28706241   PMID:28919207   PMID:28973166   PMID:29166838  
PMID:29241539   PMID:29253516   PMID:29381137   PMID:29523844   PMID:29584618   PMID:29589323   PMID:29615468   PMID:29875237   PMID:29975347   PMID:30037926   PMID:30061605   PMID:30430919  
PMID:30524266   PMID:30612733   PMID:30934765   PMID:30977543   PMID:31196952   PMID:31578352   PMID:31685654   PMID:31996225   PMID:32460020   PMID:32579702   PMID:32669337   PMID:32892421  
PMID:33307981   PMID:34321664   PMID:34400627   PMID:34487017   PMID:34599818   PMID:34639085   PMID:34851661   PMID:35302859   PMID:35306300   PMID:35579787   PMID:35713404   PMID:35714603  
PMID:36008159   PMID:36685938   PMID:37080382   PMID:37494420   PMID:38003427   PMID:38012403   PMID:38117901   PMID:38118180   PMID:38165021   PMID:38195497   PMID:38639409   PMID:38646645  
PMID:39217171  


Genomics

Comparative Map Data
Ngf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393102,377,235 - 102,428,329 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3102,377,235 - 102,428,329 (+)EnsemblGRCm39 Ensembl
GRCm383102,469,919 - 102,521,013 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3102,469,919 - 102,521,013 (+)EnsemblGRCm38mm10GRCm38
MGSCv373102,273,851 - 102,324,936 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363102,598,989 - 102,650,066 (+)NCBIMGSCv36mm8
Celera3104,674,123 - 104,724,621 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.25NCBI
NGF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381115,285,917 - 115,338,249 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1115,285,904 - 115,338,770 (-)EnsemblGRCh38hg38GRCh38
GRCh371115,828,538 - 115,880,870 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361115,630,060 - 115,682,380 (-)NCBINCBI36Build 36hg18NCBI36
Build 341115,540,580 - 115,592,899NCBI
Celera1114,057,456 - 114,109,776 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1113,686,915 - 113,739,240 (-)NCBIHuRef
CHM1_11115,943,440 - 115,995,752 (-)NCBICHM1_1
T2T-CHM13v2.01115,297,082 - 115,349,408 (-)NCBIT2T-CHM13v2.0
Ngf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82192,589,580 - 192,642,971 (+)NCBIGRCr8
mRatBN7.22189,901,058 - 189,954,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2189,901,058 - 189,954,452 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2197,519,156 - 197,572,237 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02195,377,191 - 195,431,562 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02190,206,371 - 190,261,316 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02204,886,158 - 204,939,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2204,886,202 - 204,940,453 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02224,316,210 - 224,369,663 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42197,621,726 - 197,632,960 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2182,322,945 - 182,375,918 (+)NCBICelera
RH 3.4 Map21294.4RGD
Cytogenetic Map2q34NCBI
Ngf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543518,581,808 - 18,601,059 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543518,581,889 - 18,633,330 (-)NCBIChiLan1.0ChiLan1.0
NGF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21107,940,198 - 107,992,897 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11107,539,320 - 107,592,441 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0187,223,597 - 87,276,759 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11122,272,750 - 122,325,909 (+)NCBIpanpan1.1PanPan1.1panPan2
NGF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11752,900,647 - 52,901,607 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1752,900,647 - 52,901,607 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1752,550,068 - 52,550,845 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01753,781,750 - 53,834,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1753,781,750 - 53,782,527 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11752,820,833 - 52,821,610 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01752,855,816 - 52,856,593 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01753,428,944 - 53,429,721 (-)NCBIUU_Cfam_GSD_1.0
Ngf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505813,803,009 - 13,853,189 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936627635,788 - 645,364 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936627635,784 - 641,290 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NGF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4105,256,749 - 105,307,837 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14105,256,691 - 105,307,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24115,436,784 - 115,446,393 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NGF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12018,361,795 - 18,413,987 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2018,413,108 - 18,413,833 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603821,083,578 - 21,157,325 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ngf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477211,010,845 - 11,070,017 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477211,009,765 - 11,070,050 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ngf
2359 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:368
Count of miRNA genes:179
Interacting mature miRNAs:182
Transcripts:ENSMUST00000035952, ENSMUST00000106925
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
8655600Cia5b_mcollagen induced arthritis QTL 5b (mouse)Not determined3100655184103744779Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse

Markers in Region
M14805  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383102,520,899 - 102,521,013UniSTSGRCm38
MGSCv373102,324,822 - 102,324,936UniSTSGRCm37
Celera3104,724,507 - 104,724,621UniSTS
Cytogenetic Map3F2.2UniSTS
Whitehead_YAC3 UniSTS
Ngfb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383102,520,755 - 102,520,893UniSTSGRCm38
MGSCv373102,324,678 - 102,324,816UniSTSGRCm37
Celera3104,724,363 - 104,724,501UniSTS
Cytogenetic Map3F2.2UniSTS
cM Map348.5UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000035952   ⟹   ENSMUSP00000040345
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3102,377,235 - 102,428,164 (+)Ensembl
GRCm38.p6 Ensembl3102,469,919 - 102,520,848 (+)Ensembl
Ensembl Acc Id: ENSMUST00000106925   ⟹   ENSMUSP00000102538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3102,377,244 - 102,428,329 (+)Ensembl
GRCm38.p6 Ensembl3102,469,928 - 102,521,013 (+)Ensembl
Ensembl Acc Id: ENSMUST00000198168   ⟹   ENSMUSP00000143428
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3102,377,244 - 102,417,158 (+)Ensembl
GRCm38.p6 Ensembl3102,469,928 - 102,509,842 (+)Ensembl
Ensembl Acc Id: ENSMUST00000198644   ⟹   ENSMUSP00000142801
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3102,396,010 - 102,428,311 (+)Ensembl
GRCm38.p6 Ensembl3102,488,694 - 102,520,995 (+)Ensembl
RefSeq Acc Id: NM_001112698   ⟹   NP_001106168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393102,377,235 - 102,428,329 (+)NCBI
GRCm383102,469,919 - 102,521,013 (+)NCBI
MGSCv373102,273,851 - 102,324,936 (+)RGD
Celera3104,674,114 - 104,724,621 (+)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_013609   ⟹   NP_038637
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393102,377,235 - 102,428,329 (+)NCBI
GRCm383102,469,919 - 102,521,013 (+)NCBI
MGSCv373102,273,851 - 102,324,936 (+)RGD
Celera3104,674,114 - 104,724,621 (+)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501108   ⟹   XP_006501171
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393102,413,340 - 102,428,323 (+)NCBI
GRCm383102,508,951 - 102,521,007 (+)NCBI
Sequence:
RefSeq Acc Id: NP_038637   ⟸   NM_013609
- Peptide Label: isoform A
- UniProtKB: Q6LDU8 (UniProtKB/TrEMBL),   A0A0G2JEK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106168   ⟸   NM_001112698
- Peptide Label: isoform B precursor
- UniProtKB: Q63864 (UniProtKB/Swiss-Prot),   Q6LDB7 (UniProtKB/Swiss-Prot),   P01139 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501171   ⟸   XM_006501108
- Peptide Label: isoform X1
- UniProtKB: Q6LDU8 (UniProtKB/TrEMBL),   A0A0G2JEK0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000142801   ⟸   ENSMUST00000198644
Ensembl Acc Id: ENSMUSP00000143428   ⟸   ENSMUST00000198168
Ensembl Acc Id: ENSMUSP00000102538   ⟸   ENSMUST00000106925
Ensembl Acc Id: ENSMUSP00000040345   ⟸   ENSMUST00000035952
Protein Domains
Nerve growth factor-related

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P01139-F1-model_v2 AlphaFold P01139 1-241 view protein structure

Promoters
RGD ID:6834152
Promoter ID:MM_KWN:35571
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   Kidney,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000035952,   NM_001112698,   NM_013609
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363102,273,661 - 102,274,161 (+)MPROMDB
RGD ID:6881834
Promoter ID:EPDNEW_M4368
Type:multiple initiation site
Name:Ngf_1
Description:Mus musculus nerve growth factor , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383102,469,928 - 102,469,988EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97321 AgrOrtholog
Ensembl Genes ENSMUSG00000027859 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035952 ENTREZGENE
  ENSMUST00000035952.5 UniProtKB/Swiss-Prot
  ENSMUST00000106925 ENTREZGENE
  ENSMUST00000106925.9 UniProtKB/TrEMBL
  ENSMUST00000198168.5 UniProtKB/TrEMBL
  ENSMUST00000198644.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nerve_growth_factor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nerve_growth_factor-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nerve_growth_factor_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nerve_growth_factor_bsu_mml UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nerve_growth_factor_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18049 UniProtKB/Swiss-Prot
MGD MGI:97321 ENTREZGENE
NCBI Gene 18049 ENTREZGENE
PANTHER BETA-NERVE GROWTH FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11589 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB NGF RGD
PhenoGen Ngf PhenoGen
PIRSF NGF UniProtKB/Swiss-Prot
PRINTS MAMLNGFBETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NGFBETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART NGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JEK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JG51_MOUSE UniProtKB/TrEMBL
  NGF_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q63864 ENTREZGENE
  Q6LDB7 ENTREZGENE
  Q6LDU8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q63864 UniProtKB/Swiss-Prot
  Q6LDB7 UniProtKB/Swiss-Prot