Myh11 (myosin, heavy polypeptide 11, smooth muscle) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Myh11 (myosin, heavy polypeptide 11, smooth muscle) Mus musculus
Analyze
Symbol: Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
RGD ID: 10947
MGI Page MGI
Description: Enables cytoskeletal motor activity. Acts upstream of or within smooth muscle contraction. Located in brush border; smooth muscle contractile fiber; and stress fiber. Part of muscle myosin complex. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and vascular system. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome; patent ductus arteriosus; and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AV071570; myosin heavy chain 11, smooth muscle; myosin heavy chain, smooth muscle isoform; myosin-11; SM; SM1; SM2; smMH; smMHC
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391614,012,392 - 14,109,227 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1614,012,399 - 14,109,236 (-)EnsemblGRCm39 Ensembl
GRCm381614,194,527 - 14,292,188 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1614,194,535 - 14,291,372 (-)EnsemblGRCm38mm10GRCm38
MGSCv371614,194,620 - 14,291,501 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361614,108,478 - 14,204,941 (-)NCBIMGSCv36mm8
Celera1614,801,022 - 14,896,521 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-noradrenaline  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (ISO)
Brodifacoum  (ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
cisplatin  (ISO)
corticosterone  (ISO)
cyclosporin A  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (ISO)
doramapimod  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
ethylparaben  (ISO)
graphite  (ISO)
L-ascorbic acid  (ISO)
lipopolysaccharide  (ISO)
losartan  (ISO)
methapyrilene  (ISO)
nickel atom  (ISO)
nifedipine  (ISO)
nitrofen  (ISO)
ozone  (EXP)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (ISO)
pioglitazone  (EXP)
potassium dichromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
Theaflavin 3,3'-digallate  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
undecane  (ISO)
urethane  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Utilization of Whole Exome Sequencing to Identify Causative Mutations in Familial Congenital Heart Disease. LaHaye S, etal., Circ Cardiovasc Genet. 2016 Aug;9(4):320-9. doi: 10.1161/CIRCGENETICS.115.001324. Epub 2016 Jul 14.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Proteomic analysis of aortic smooth muscle cell secretions reveals an association of myosin heavy chain 11 with abdominal aortic aneurysm. Yokoyama U, etal., Am J Physiol Heart Circ Physiol. 2018 Jul 13. doi: 10.1152/ajpheart.00329.2018.
13. Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. Zhu L, etal., Nat Genet. 2006 Mar;38(3):343-9. Epub 2006 Jan 29.
Additional References at PubMed
PMID:7684189   PMID:7842732   PMID:7923625   PMID:8276405   PMID:8593698   PMID:8620598   PMID:8635248   PMID:8636144   PMID:8929537   PMID:8970733   PMID:9125171   PMID:9435283  
PMID:9438424   PMID:9671592   PMID:9876177   PMID:10349636   PMID:10415359   PMID:10615124   PMID:10854329   PMID:10906778   PMID:11042159   PMID:11076861   PMID:11121372   PMID:11208532  
PMID:11715025   PMID:11934868   PMID:12372799   PMID:12477932   PMID:12496475   PMID:12562924   PMID:12668734   PMID:12781691   PMID:12959948   PMID:15044690   PMID:15135218   PMID:15136151  
PMID:15140746   PMID:15331365   PMID:15368895   PMID:15817462   PMID:16141072   PMID:16141073   PMID:16316347   PMID:16413472   PMID:16537907   PMID:16618389   PMID:16887829   PMID:16973711  
PMID:17079275   PMID:17172448   PMID:17183527   PMID:17392380   PMID:17452023   PMID:17490411   PMID:17940206   PMID:18287559   PMID:18462699   PMID:18612081   PMID:18776146   PMID:19000842  
PMID:19011095   PMID:19052105   PMID:19179305   PMID:19217425   PMID:19369400   PMID:19619540   PMID:19835856   PMID:19897741   PMID:19937203   PMID:20007544   PMID:20013655   PMID:20019329  
PMID:20059958   PMID:20110314   PMID:20439457   PMID:20881014   PMID:21041690   PMID:21068062   PMID:21282332   PMID:21371421   PMID:21512159   PMID:21693521   PMID:21778429   PMID:21873635  
PMID:21932312   PMID:21979435   PMID:22114352   PMID:22160378   PMID:22331032   PMID:22342504   PMID:22485132   PMID:22511748   PMID:22687751   PMID:22723298   PMID:22772757   PMID:22794259  
PMID:22833126   PMID:22926762   PMID:22975322   PMID:23135699   PMID:23178125   PMID:23314172   PMID:23319608   PMID:23371862   PMID:23671695   PMID:23760954   PMID:23946491   PMID:23946498  
PMID:24068960   PMID:24335256   PMID:24401276   PMID:24457600   PMID:24727670   PMID:24894773   PMID:25127126   PMID:25139858   PMID:25145936   PMID:25150979   PMID:25535917   PMID:25631042  
PMID:25670798   PMID:26020233   PMID:26057579   PMID:26113728   PMID:26453897   PMID:26479710   PMID:26481065   PMID:26542011   PMID:26552887   PMID:26821812   PMID:26854927   PMID:26858344  
PMID:26984772   PMID:27253890   PMID:27378146   PMID:27456656   PMID:28036337   PMID:28049658   PMID:28292896   PMID:28334964   PMID:28378742   PMID:28527294   PMID:28634551   PMID:28655168  
PMID:28779009   PMID:28797033   PMID:28924218   PMID:28943241   PMID:28973166   PMID:29018080   PMID:29196262   PMID:29199018   PMID:29251627   PMID:29428562   PMID:29494672   PMID:29518331  
PMID:29530978   PMID:29891665   PMID:29932067   PMID:29961567   PMID:30153454   PMID:30409884   PMID:30478225   PMID:30916783   PMID:31024075   PMID:31112136   PMID:31201155   PMID:31365875  
PMID:31513549   PMID:31624376   PMID:31634485   PMID:31870435   PMID:32011766   PMID:32220188   PMID:32325033   PMID:32483447   PMID:32520726   PMID:32578852   PMID:32618127   PMID:32909945  
PMID:32929473   PMID:33315499   PMID:33356387   PMID:33424621   PMID:33846639   PMID:34569705   PMID:34653670   PMID:34732321   PMID:34818545   PMID:34851738   PMID:35037469   PMID:35103284  
PMID:35108221   PMID:35126469   PMID:35450884   PMID:35614093   PMID:35831318   PMID:35905011   PMID:36094016   PMID:36293380   PMID:36354355   PMID:37142655   PMID:37289544   PMID:37647896  
PMID:37873566   PMID:37953328   PMID:38644513   PMID:39217171  


Genomics

Comparative Map Data
Myh11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391614,012,392 - 14,109,227 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1614,012,399 - 14,109,236 (-)EnsemblGRCm39 Ensembl
GRCm381614,194,527 - 14,292,188 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1614,194,535 - 14,291,372 (-)EnsemblGRCm38mm10GRCm38
MGSCv371614,194,620 - 14,291,501 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361614,108,478 - 14,204,941 (-)NCBIMGSCv36mm8
Celera1614,801,022 - 14,896,521 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.71NCBI
MYH11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381615,703,135 - 15,857,028 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1615,703,135 - 15,858,438 (-)EnsemblGRCh38hg38GRCh38
GRCh371615,796,992 - 15,950,885 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361615,704,493 - 15,858,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 341615,704,494 - 15,858,369NCBI
Celera1615,477,469 - 15,631,373 (-)NCBICelera
Cytogenetic Map16p13.11NCBI
HuRef1615,190,414 - 15,344,394 (-)NCBIHuRef
CHM1_11615,881,372 - 16,035,249 (-)NCBICHM1_1
T2T-CHM13v2.01615,708,067 - 15,861,962 (-)NCBIT2T-CHM13v2.0
Myh11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,250,554 - 1,345,681 (+)NCBIGRCr8
mRatBN7.210743,364 - 838,459 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10743,685 - 838,459 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx105,440,444 - 5,535,220 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01035,030,622 - 35,125,399 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010754,866 - 851,396 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010764,421 - 859,184 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10764,421 - 859,184 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01011,444,263 - 11,538,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410666,709 - 776,540 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110767,179 - 776,535 (+)NCBI
Celera1011,333,535 - 11,428,078 (+)NCBICelera
Cytogenetic Map10q11NCBI
Myh11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955442528,880 - 644,264 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955442528,317 - 644,252 (-)NCBIChiLan1.0ChiLan1.0
MYH11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21815,760,905 - 15,915,299 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11619,543,025 - 19,698,594 (-)NCBINHGRI_mPanPan1
PanPan1.11616,006,840 - 16,091,058 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1616,007,168 - 16,091,058 (-)Ensemblpanpan1.1panPan2
MYH11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,041,330 - 28,157,277 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,041,318 - 28,262,184 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,405,013 - 29,520,689 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0628,204,726 - 28,320,508 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl628,204,776 - 28,320,502 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1628,007,790 - 28,123,460 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0627,898,014 - 28,013,477 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,303,247 - 28,418,936 (+)NCBIUU_Cfam_GSD_1.0
Myh11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344115,125,200 - 115,215,681 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365013,222,300 - 3,313,610 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365013,223,057 - 3,313,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl37,002,735 - 7,143,095 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.137,002,667 - 7,143,093 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MYH11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1514,723,930 - 14,879,390 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl514,725,504 - 14,879,198 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606815,158,855 - 15,315,982 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myh11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624782270,731 - 354,838 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624782270,183 - 373,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myh11
3409 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:244
Interacting mature miRNAs:276
Transcripts:ENSMUST00000090287
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1302106Rapop1_mradiation-induced apoptosis 1 (mouse)Not determined16378077915731053Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
AV071570  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381614,194,707 - 14,194,800UniSTSGRCm38
MGSCv371614,194,800 - 14,194,893UniSTSGRCm37
Celera1614,801,202 - 14,801,295UniSTS
Cytogenetic Map16A1UniSTS
cM Map165.0UniSTS
Whitehead/MRC_RH3578.66UniSTS
D85923  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381614,194,963 - 14,195,050UniSTSGRCm38
MGSCv371614,195,056 - 14,195,143UniSTSGRCm37
Celera1614,801,458 - 14,801,545UniSTS
Cytogenetic Map16A1UniSTS
cM Map165.0UniSTS
Whitehead/MRC_RH16116.18UniSTS
Myh11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381614,239,432 - 14,239,539UniSTSGRCm38
MGSCv371614,239,525 - 14,239,632UniSTSGRCm37
Celera1614,845,626 - 14,845,733UniSTS
Cytogenetic Map16A1UniSTS
cM Map165.0UniSTS
Myh11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16A1UniSTS
cM Map165.0UniSTS
Myh11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381614,200,978 - 14,201,077UniSTSGRCm38
MGSCv371614,201,071 - 14,201,170UniSTSGRCm37
Celera1614,807,473 - 14,807,572UniSTS
Cytogenetic Map16A1UniSTS
cM Map165.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001161775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC164291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02122024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02122026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK173045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D85923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D85924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L25860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S81516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U53469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000090287   ⟹   ENSMUSP00000087756
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,012,399 - 14,109,236 (-)Ensembl
GRCm38.p6 Ensembl1614,194,535 - 14,291,372 (-)Ensembl
Ensembl Acc Id: ENSMUST00000230397   ⟹   ENSMUSP00000155052
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,012,764 - 14,109,227 (-)Ensembl
GRCm38.p6 Ensembl1614,194,900 - 14,291,363 (-)Ensembl
Ensembl Acc Id: ENSMUST00000230643
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,067,396 - 14,109,230 (-)Ensembl
GRCm38.p6 Ensembl1614,249,532 - 14,291,366 (-)Ensembl
Ensembl Acc Id: ENSMUST00000231567   ⟹   ENSMUSP00000156021
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,012,512 - 14,109,229 (-)Ensembl
GRCm38.p6 Ensembl1614,194,648 - 14,291,365 (-)Ensembl
RefSeq Acc Id: NM_001161775   ⟹   NP_001155247
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,012,396 - 14,109,227 (-)NCBI
GRCm381614,194,527 - 14,291,408 (-)ENTREZGENE
MGSCv371614,194,620 - 14,291,501 (-)RGD
Celera1614,801,022 - 14,896,521 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001402795   ⟹   NP_001389724
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,012,396 - 14,109,227 (-)NCBI
RefSeq Acc Id: NM_001402796   ⟹   NP_001389725
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,012,396 - 14,109,227 (-)NCBI
RefSeq Acc Id: NM_013607   ⟹   NP_038635
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,012,396 - 14,109,227 (-)NCBI
GRCm381614,194,527 - 14,291,408 (-)ENTREZGENE
MGSCv371614,194,620 - 14,291,501 (-)RGD
Celera1614,801,022 - 14,896,521 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521845   ⟹   XP_006521908
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,012,392 - 14,042,253 (-)NCBI
GRCm381614,194,528 - 14,224,389 (-)NCBI
Sequence:
RefSeq Acc Id: NP_038635   ⟸   NM_013607
- Peptide Label: isoform 1
- UniProtKB: A0A2R8VHF9 (UniProtKB/TrEMBL),   Q69ZX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001155247   ⟸   NM_001161775
- Peptide Label: isoform 2
- UniProtKB: E9QPE7 (UniProtKB/TrEMBL),   Q69ZX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521908   ⟸   XM_006521845
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSMUSP00000087756   ⟸   ENSMUST00000090287
Ensembl Acc Id: ENSMUSP00000156021   ⟸   ENSMUST00000231567
Ensembl Acc Id: ENSMUSP00000155052   ⟸   ENSMUST00000230397
RefSeq Acc Id: NP_001389724   ⟸   NM_001402795
- Peptide Label: isoform 3
- UniProtKB: A0A338P6K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001389725   ⟸   NM_001402796
- Peptide Label: isoform 4
Protein Domains
IQ   Myosin motor   Myosin N-terminal SH3-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08638-F1-model_v2 AlphaFold O08638 1-1972 view protein structure

Promoters
RGD ID:6827263
Promoter ID:MM_KWN:20205
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000115792,   NM_001161775,   NM_013607,   UC007YHF.1,   UC007YHG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361614,291,261 - 14,291,761 (-)MPROMDB
RGD ID:8685522
Promoter ID:EPDNEW_M20792
Type:multiple initiation site
Name:Myh11_1
Description:Mus musculus myosin, heavy polypeptide 11, smooth muscle , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381614,291,363 - 14,291,423EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102643 AgrOrtholog
Ensembl Genes ENSMUSG00000018830 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000090287 ENTREZGENE
  ENSMUST00000090287.5 UniProtKB/TrEMBL
  ENSMUST00000230397 ENTREZGENE
  ENSMUST00000230397.2 UniProtKB/TrEMBL
  ENSMUST00000231567 ENTREZGENE
  ENSMUST00000231567.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.1590 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin, subunit A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17880 UniProtKB/TrEMBL
MGD MGI:102643 ENTREZGENE
NCBI Gene 17880 ENTREZGENE
PANTHER MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOSIN-11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myh11 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MYSc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHF9 ENTREZGENE, UniProtKB/TrEMBL
  A0A338P6K2 ENTREZGENE, UniProtKB/TrEMBL
  E9QPE7 ENTREZGENE, UniProtKB/TrEMBL
  MYH11_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q69ZX3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O08639 UniProtKB/Swiss-Prot
  Q62462 UniProtKB/Swiss-Prot
  Q64195 UniProtKB/Swiss-Prot