Abcc1 (ATP-binding cassette, sub-family C member 1) - Rat Genome Database

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Gene: Abcc1 (ATP-binding cassette, sub-family C member 1) Mus musculus
Analyze
Symbol: Abcc1
Name: ATP-binding cassette, sub-family C member 1
RGD ID: 10919
MGI Page MGI
Description: Enables several functions, including ABC-type transporter activity; glutathione transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in several processes, including cellular response to amyloid-beta; cobalamin transport; and leukotriene transport. Located in plasma membrane. Is active in basal plasma membrane. Is expressed in several structures, including embryo mesenchyme; genitourinary system; hemolymphoid system; nervous system; and nose. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 77 and chronic obstructive pulmonary disease. Orthologous to human ABCC1 (ATP binding cassette subfamily C member 1 (ABCC1 blood group)).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Abcc; Abcc1a; Abcc1b; ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; glutathione-S-conjugate-translocating ATPase ABCC1; leukotriene C(4) transporter; LTC4 transporter; M; Md; Mdrap; Mr; MRP; Mrp1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391614,179,317 - 14,292,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1614,179,422 - 14,293,601 (+)EnsemblGRCm39 Ensembl
GRCm381614,361,453 - 14,474,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1614,361,558 - 14,475,737 (+)EnsemblGRCm38mm10GRCm38
MGSCv371614,361,653 - 14,474,968 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361614,275,138 - 14,388,453 (+)NCBIMGSCv36mm8
Celera1614,966,079 - 15,077,783 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-viniferin  (ISO)
(+)-pilocarpine  (ISO)
(+)-taxifolin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(-)-matairesinol  (ISO)
(-)-trans-epsilon-viniferin  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-adrenaline  (ISO)
(S)-colchicine  (ISO)
(S)-naringenin  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (EXP)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
15alpha-hydroxytestosterone  (EXP)
16alpha-hydroxytestosterone  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 17-glucosiduronic acid  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-naphthol  (EXP)
2-tert-butylhydroquinone  (EXP,ISO)
26-hydroxycholesterol  (ISO)
3',4',7-trihydroxyisoflavone  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4',5,7-trihydroxy-3'-methoxyflavone  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-nitrophenol  (EXP)
4-nitroquinoline N-oxide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxypsoralen  (ISO)
6-carboxyfluorescein  (ISO)
6beta-hydroxytestosterone  (EXP)
8-Br-cAMP  (ISO)
[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol  (ISO)
abamectin  (EXP,ISO)
acetamide  (ISO)
acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester  (ISO)
acetochlor  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
ADP  (ISO)
aflatoxin B1  (ISO)
afrormosin  (ISO)
aldehydo-D-glucose  (EXP)
allyl alcohol  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
antimony(0)  (ISO)
apigenin  (ISO)
arotinoid acid  (ISO)
arsane  (ISO)
arsenic acid  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
ATP  (EXP,ISO)
baicalein  (ISO)
beclomethasone  (ISO)
benzbromarone  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bilirubin IXalpha  (ISO)
biochanin A  (ISO)
biopterin  (EXP)
bisdemethoxycurcumin  (ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcein  (EXP,ISO)
calcein am  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
Cannabinol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carboplatin  (ISO)
celecoxib  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chlorambucil  (ISO)
chlorogenic acid  (EXP)
chloroprene  (EXP)
chloroquine  (ISO)
chlorpropham  (EXP)
chlorpyrifos  (ISO)
cholic acid  (ISO)
choline  (EXP,ISO)
chromium(6+)  (EXP)
chrysin  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (EXP)
dabrafenib  (ISO)
daidzein  (ISO)
daunorubicin  (EXP,ISO)
delta-tocotrienol  (EXP)
demethoxycurcumin  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenzo[a,l]pyrene  (EXP)
dichlorine  (ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
diosmetin  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disulfiram  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
emamectin  (EXP,ISO)
enasidenib  (ISO)
epoxiconazole  (EXP)
eriodictyol  (ISO)
etacrynic acid  (ISO)
etoposide  (EXP,ISO)
fenitrothion  (EXP)
ferrostatin-1  (ISO)
flavone  (ISO)
flavonoids  (ISO)
Fluo-3  (EXP)
folic acid  (EXP,ISO)
formononetin  (ISO)
fosinopril  (ISO)
furfural  (ISO)
galangin  (ISO)
gallocatechin  (ISO)
gamma-tocopherol  (ISO)
geneticin  (ISO)
genistein  (ISO)
ginsenoside Re  (ISO)
ginsenoside Rg1  (ISO)
glucose  (EXP)
glutathione  (EXP,ISO)
glutathione disulfide  (EXP,ISO)
glyburide  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
Grepafloxacin  (EXP)
haloperidol  (ISO)
heparin  (ISO)
heptachlor  (ISO)
hesperetin  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (EXP)
hypericin  (ISO)
hypochlorous acid  (EXP)
idarubicin  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
irinotecan  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
iron(III) nitrilotriacetate  (EXP)
isoflavones  (ISO)
isoniazide  (ISO)
isoorientin  (ISO)
isorhamnetin  (ISO)
ivermectin  (EXP,ISO)
kaempferol  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-erythro-biopterin  (EXP)
L-methionine  (EXP,ISO)
lead diacetate  (EXP,ISO)
leflunomide  (ISO)
leukotriene C4  (ISO)
levetiracetam  (ISO)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (EXP,ISO)
lithocholic acid sulfate  (ISO)
loratadine  (ISO)
lovastatin  (EXP)
luteolin  (ISO)
LY294002  (ISO)
mebendazole  (ISO)
mefloquine  (ISO)
melphalan  (ISO)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxsalen  (ISO)
methoxychlor  (EXP)
methylarsonic acid  (ISO)
metiram  (ISO)
mitomycin C  (ISO)
MK 571  (EXP,ISO)
montelukast  (ISO)
morin  (ISO)
myricetin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-ethylmaleimide  (ISO)
nelfinavir  (ISO)
nemorubicin  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
nimustine  (ISO)
nitric oxide  (EXP)
nobiletin  (ISO)
notoginsenoside R1  (ISO)
NS-398  (ISO)
Nutlin-3  (ISO)
oltipraz  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
Pentoxifylline  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
phenothiazines  (ISO)
phenytoin  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
proanthocyanidin  (ISO)
probenecid  (EXP,ISO)
prodigiosin  (ISO)
prostaglandins E  (ISO)
puromycin  (ISO)
quercetin  (EXP,ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
robinetin  (ISO)
robinin  (ISO)
romidepsin  (ISO)
S-(2,4-dinitrophenyl)glutathione  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
saquinavir  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
senecionine  (EXP)
silicon dioxide  (EXP)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silver(1+) nitrate  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (EXP)
sodium chloride  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sodium stibogluconate  (EXP)
sorafenib  (ISO)
soybean oil  (ISO)
streptozocin  (EXP)
sulfinpyrazone  (ISO)
sulforaphane  (EXP)
sulindac  (ISO)
superoxide  (EXP)
tamoxifen  (EXP,ISO)
tartrazine  (ISO)
taurocholic acid  (ISO)
taurodeoxycholic acid  (ISO)
tauroursodeoxycholic acid  (ISO)
taxane  (ISO)
Technetium tc 99m sestamibi  (ISO)
temozolomide  (ISO)
teniposide  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thiethylperazine  (EXP)
thioacetamide  (ISO)
Thiotepa  (ISO)
tiagabine  (ISO)
titanium dioxide  (EXP,ISO)
tocopherol  (ISO)
toluene  (ISO)
topiramate  (ISO)
triclosan  (ISO)
trimethylarsine oxide  (ISO)
triptonide  (EXP)
tunicamycin  (EXP)
ursodeoxycholic acid  (ISO)
vadimezan  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
verapamil  (EXP,ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vincristine  (EXP,ISO)
XAV939  (ISO)
zafirlukast  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zileuton  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. Buchler M, etal., J Biol Chem 1996 Jun 21;271(25):15091-8.
2. Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD. Budulac SE, etal., Respir Res. 2010 May 20;11:60.
3. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, etal., Nature 2002 Dec 5;420(6915):586-90.
4. The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress. Hirrlinger J, etal., J Neurochem 2001 Jan;76(2):627-36.
5. Evaluation of MRP1-5 gene expression in cystic fibrosis patients homozygous for the delta F508 mutation. Hurbain I, etal., Pediatr Res. 2003 Nov;54(5):627-34. Epub 2003 Aug 20.
6. Accumulation of murine amyloid-ß mimics early Alzheimer's disease. Krohn M, etal., Brain. 2015 Aug;138(Pt 8):2370-82. doi: 10.1093/brain/awv137. Epub 2015 May 18.
7. Circ_0048856 competes with ABCC1 for miR-193a-5p/miR-98-5p binding sites to promote the cisplatin resistance and tumorigenesis in lung cancer. Liu L, etal., J Chemother. 2022 Mar 15:1-14. doi: 10.1080/1120009X.2022.2043515.
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. MGD IEA MGD IEA
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia. Schultz MJ, etal., J Immunol. 2001 Mar 15;166(6):4059-64.
17. Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients. van der Deen M, etal., Virchows Arch. 2006 Dec;449(6):682-8. Epub 2006 Oct 27.
18. Role of multidrug resistance-associated protein 1 in the pathogenesis of allergic airway inflammation. Yoshioka M, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L30-6. Epub 2008 Oct 17.
Additional References at PubMed
PMID:7671247   PMID:7842732   PMID:8649356   PMID:8889548   PMID:8968083   PMID:8973633   PMID:9281595   PMID:9359705   PMID:9393741   PMID:9524197   PMID:9730882   PMID:9778357  
PMID:10349636   PMID:10413292   PMID:10581366   PMID:10581368   PMID:10675353   PMID:10708515   PMID:10922068   PMID:10944550   PMID:11042159   PMID:11076861   PMID:11114332   PMID:11217851  
PMID:11245453   PMID:11278867   PMID:11409873   PMID:11689020   PMID:11855834   PMID:12296850   PMID:12477932   PMID:12504668   PMID:12516967   PMID:12951053   PMID:14610273   PMID:14681479  
PMID:14742140   PMID:15240672   PMID:15328029   PMID:15747579   PMID:15749056   PMID:15802388   PMID:15886284   PMID:16123331   PMID:16141072   PMID:16141073   PMID:16361063   PMID:16403838  
PMID:16458308   PMID:16517726   PMID:17003472   PMID:17008412   PMID:17075973   PMID:17169333   PMID:17229149   PMID:17272743   PMID:17540781   PMID:17617921   PMID:17845218   PMID:17967808  
PMID:18287559   PMID:18506003   PMID:18799693   PMID:19067785   PMID:19685171   PMID:19894120   PMID:19897579   PMID:20178799   PMID:21045108   PMID:21112334   PMID:21267068   PMID:21305474  
PMID:21609321   PMID:21763326   PMID:21799180   PMID:21873635   PMID:21881209   PMID:22084240   PMID:22426312   PMID:22442691   PMID:22451472   PMID:22464990   PMID:22522787   PMID:22545122  
PMID:22563480   PMID:22914987   PMID:23168528   PMID:23596979   PMID:24219083   PMID:24952961   PMID:25403683   PMID:26200696   PMID:26416771   PMID:26454883   PMID:26507673   PMID:26822305  
PMID:26908299   PMID:26961872   PMID:27378146   PMID:27535620   PMID:27568566   PMID:28025333   PMID:29976647   PMID:30146480   PMID:30323255   PMID:30550785   PMID:31189668   PMID:32325033  
PMID:32554809   PMID:34029289   PMID:34088745   PMID:36070769   PMID:38829241   PMID:38870779   PMID:38926988   PMID:38951883  


Genomics

Comparative Map Data
Abcc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391614,179,317 - 14,292,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1614,179,422 - 14,293,601 (+)EnsemblGRCm39 Ensembl
GRCm381614,361,453 - 14,474,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1614,361,558 - 14,475,737 (+)EnsemblGRCm38mm10GRCm38
MGSCv371614,361,653 - 14,474,968 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361614,275,138 - 14,388,453 (+)NCBIMGSCv36mm8
Celera1614,966,079 - 15,077,783 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.75NCBI
ABCC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381615,949,143 - 16,143,053 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1615,949,138 - 16,143,257 (+)EnsemblGRCh38hg38GRCh38
GRCh371616,043,473 - 16,236,910 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361615,950,935 - 16,144,432 (+)NCBINCBI36Build 36hg18NCBI36
Build 341615,950,934 - 16,143,774NCBI
Celera1615,781,784 - 15,917,085 (+)NCBICelera
Cytogenetic Map16p13.11NCBI
HuRef1615,436,705 - 15,630,893 (+)NCBIHuRef
CHM1_11616,185,916 - 16,321,192 (+)NCBICHM1_1
T2T-CHM13v2.01615,954,068 - 16,147,908 (+)NCBIT2T-CHM13v2.0
Abcc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,022,041 - 1,162,431 (-)NCBIGRCr8
mRatBN7.210528,961 - 655,179 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10531,812 - 655,114 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx105,228,580 - 5,351,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01035,213,968 - 35,337,275 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010543,174 - 666,513 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010549,537 - 672,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10549,883 - 672,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01011,232,233 - 11,354,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410452,239 - 575,705 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110452,238 - 575,705 (-)NCBI
Celera1011,130,945 - 11,246,232 (-)NCBICelera
Cytogenetic Map10q11NCBI
Abcc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955442729,316 - 860,290 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955442729,322 - 858,826 (+)NCBIChiLan1.0ChiLan1.0
ABCC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21816,295,604 - 16,482,561 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11619,921,573 - 20,108,728 (+)NCBINHGRI_mPanPan1
ABCC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1627,855,702 - 27,950,140 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl627,855,702 - 27,989,331 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,219,306 - 29,353,121 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0628,018,483 - 28,152,589 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl628,010,824 - 28,152,766 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1627,821,973 - 27,955,836 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0627,711,967 - 27,845,729 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,117,166 - 28,251,282 (-)NCBIUU_Cfam_GSD_1.0
Abcc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344115,297,821 - 115,369,238 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365013,401,285 - 3,470,460 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365013,400,971 - 3,467,061 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl328,360,873 - 28,473,456 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1328,360,868 - 28,472,940 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2329,082,788 - 29,172,693 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABCC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1514,972,589 - 15,164,594 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl514,972,646 - 15,164,567 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606814,816,018 - 14,953,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624782449,288 - 591,310 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624782449,217 - 590,306 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abcc1
3891 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4285
Count of miRNA genes:859
Interacting mature miRNAs:1160
Transcripts:ENSMUST00000100167, ENSMUST00000130671, ENSMUST00000133454, ENSMUST00000134776, ENSMUST00000134960, ENSMUST00000144074, ENSMUST00000144676, ENSMUST00000146032, ENSMUST00000147759, ENSMUST00000154748, ENSMUST00000156089
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1302106Rapop1_mradiation-induced apoptosis 1 (mouse)Not determined16378077915731053Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
D16Ertd780e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381614,434,352 - 14,434,551UniSTSGRCm38
MGSCv371614,434,445 - 14,434,644UniSTSGRCm37
Celera1615,037,659 - 15,037,858UniSTS
Cytogenetic Map16A1UniSTS
cM Map169.9UniSTS
Abcc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16A1UniSTS
Cytogenetic Map19C3UniSTS
cM Map169.75UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001425178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_189144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF213389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI853854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC090617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP762240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000100167   ⟹   ENSMUSP00000097743
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,424 - 14,293,601 (+)Ensembl
GRCm38.p6 Ensembl1614,361,560 - 14,475,737 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130671   ⟹   ENSMUSP00000116714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,422 - 14,291,766 (+)Ensembl
GRCm38.p6 Ensembl1614,361,558 - 14,473,902 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133454   ⟹   ENSMUSP00000122656
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,422 - 14,291,766 (+)Ensembl
GRCm38.p6 Ensembl1614,361,558 - 14,473,902 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134776   ⟹   ENSMUSP00000120933
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,445 - 14,222,925 (+)Ensembl
GRCm38.p6 Ensembl1614,361,581 - 14,405,061 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134960
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,278,872 - 14,286,100 (+)Ensembl
GRCm38.p6 Ensembl1614,461,008 - 14,468,236 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144074
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,211,817 - 14,212,191 (+)Ensembl
GRCm38.p6 Ensembl1614,393,953 - 14,394,327 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144676   ⟹   ENSMUSP00000116726
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,183,626 - 14,209,307 (+)Ensembl
GRCm38.p6 Ensembl1614,365,762 - 14,391,443 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146032
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,278,877 - 14,291,906 (+)Ensembl
GRCm38.p6 Ensembl1614,461,013 - 14,474,042 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147759   ⟹   ENSMUSP00000115627
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,422 - 14,291,766 (+)Ensembl
GRCm38.p6 Ensembl1614,361,558 - 14,473,902 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154748   ⟹   ENSMUSP00000115763
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,440 - 14,214,269 (+)Ensembl
GRCm38.p6 Ensembl1614,361,576 - 14,396,405 (+)Ensembl
Ensembl Acc Id: ENSMUST00000156089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,220,224 - 14,238,607 (+)Ensembl
GRCm38.p6 Ensembl1614,402,360 - 14,420,743 (+)Ensembl
Ensembl Acc Id: ENSMUST00000230780
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1614,179,431 - 14,182,233 (+)Ensembl
GRCm38.p6 Ensembl1614,361,567 - 14,364,369 (+)Ensembl
RefSeq Acc Id: NM_001425178   ⟹   NP_001412107
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,179,439 - 14,292,739 (+)NCBI
RefSeq Acc Id: NM_008576   ⟹   NP_032602
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,179,439 - 14,292,739 (+)NCBI
GRCm381614,361,558 - 14,474,878 (+)NCBI
MGSCv371614,361,653 - 14,474,968 (+)RGD
Celera1614,966,077 - 15,077,786 (+)ENTREZGENE
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_189144
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,179,439 - 14,292,739 (+)NCBI
RefSeq Acc Id: XM_017316888   ⟹   XP_017172377
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,179,317 - 14,276,972 (+)NCBI
GRCm381614,361,453 - 14,459,108 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159813   ⟹   XP_036015706
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391614,179,408 - 14,292,743 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032602   ⟸   NM_008576
- Peptide Label: isoform 1
- UniProtKB: O35379 (UniProtKB/Swiss-Prot),   A5D6P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172377   ⟸   XM_017316888
- Peptide Label: isoform X2
- UniProtKB: Q3UDM1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000116726   ⟸   ENSMUST00000144676
Ensembl Acc Id: ENSMUSP00000116714   ⟸   ENSMUST00000130671
Ensembl Acc Id: ENSMUSP00000122656   ⟸   ENSMUST00000133454
Ensembl Acc Id: ENSMUSP00000115627   ⟸   ENSMUST00000147759
Ensembl Acc Id: ENSMUSP00000115763   ⟸   ENSMUST00000154748
Ensembl Acc Id: ENSMUSP00000097743   ⟸   ENSMUST00000100167
Ensembl Acc Id: ENSMUSP00000120933   ⟸   ENSMUST00000134776
RefSeq Acc Id: XP_036015706   ⟸   XM_036159813
- Peptide Label: isoform X3
- UniProtKB: Q8C7V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001412107   ⟸   NM_001425178
- Peptide Label: isoform 2
Protein Domains
ABC transmembrane type-1   ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35379-F1-model_v2 AlphaFold O35379 1-1528 view protein structure

Promoters
RGD ID:6826715
Promoter ID:MM_KWN:20208
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000066858,   OTTMUST00000066860,   OTTMUST00000066861,   OTTMUST00000066865,   OTTMUST00000066867,   OTTMUST00000066868
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361614,361,291 - 14,361,967 (+)MPROMDB
RGD ID:8685526
Promoter ID:EPDNEW_M20794
Type:initiation region
Name:Abcc1_1
Description:Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381614,361,582 - 14,361,642EPDNEW
RGD ID:6826716
Promoter ID:MM_KWN:20209
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000066864
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361614,365,226 - 14,365,902 (+)MPROMDB
RGD ID:6826717
Promoter ID:MM_KWN:20212
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour
Transcripts:OTTMUST00000066862,   UC007YHK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361614,460,999 - 14,461,499 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102676 AgrOrtholog
Ensembl Genes ENSMUSG00000023088 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000100167 ENTREZGENE
  ENSMUST00000100167.10 UniProtKB/Swiss-Prot
  ENSMUST00000130671 ENTREZGENE
  ENSMUST00000130671.8 UniProtKB/TrEMBL
  ENSMUST00000133454.8 UniProtKB/TrEMBL
  ENSMUST00000134776.8 UniProtKB/TrEMBL
  ENSMUST00000144676.3 UniProtKB/TrEMBL
  ENSMUST00000147759.8 UniProtKB/TrEMBL
  ENSMUST00000154748.8 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Multidrug-R_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17250 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:102676 ENTREZGENE
NCBI Gene 17250 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ABCC1 RGD
PhenoGen Abcc1 PhenoGen
PROSITE ABC_TM1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90123 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A5D6P3 ENTREZGENE, UniProtKB/TrEMBL
  D3YYJ6_MOUSE UniProtKB/TrEMBL
  D3YZY1_MOUSE UniProtKB/TrEMBL
  D3Z407_MOUSE UniProtKB/TrEMBL
  E9Q1I5_MOUSE UniProtKB/TrEMBL
  MRP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UDM1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BRD0_MOUSE UniProtKB/TrEMBL
  Q8C7V6 ENTREZGENE, UniProtKB/TrEMBL
  Q9JL41_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Abcc1  ATP-binding cassette, sub-family C member 1  Abcc1  ATP-binding cassette, sub-family C (CFTR/MRP), member 1  Symbol and/or name change 5135510 APPROVED