(+)-isolariciresinol decreases expression ISO RGD:735594 6480464 isolariciresinol results in decreased expression of LDLR protein CTD PMID:35755389 (-)-epigallocatechin 3-gallate increases expression ISO RGD:735594 6480464 epigallocatechin gallate results in increased expression of LDLR mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:735594 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LDLR mRNA CTD PMID:22079256 (-)-trans-epsilon-viniferin increases expression ISO RGD:735594 6480464 epsilon-viniferin results in increased expression of LDLR mRNA CTD PMID:22153697 (1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LDLR mRNA CTD PMID:36331819 (25R)-cholest-5-ene-3beta,26-diol decreases activity ISO RGD:735594 6480464 27-hydroxycholesterol results in decreased activity of LDLR protein CTD PMID:8820113 (25R)-cholest-5-ene-3beta,26-diol decreases expression ISO RGD:2998 6480464 27-hydroxycholesterol results in decreased expression of LDLR mRNA, 27-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:28167099 (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid multiple interactions EXP 6480464 argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol], argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides] CTD PMID:22841818 (S)-nicotine increases expression ISO RGD:735594 6480464 Nicotine results in increased expression of LDLR mRNA CTD PMID:23416264 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression ISO RGD:735594 6480464 o, p'-DDT results in decreased expression of LDLR mRNA CTD PMID:18204070 1,2-dimethylhydrazine affects expression EXP 6480464 1, 2-Dimethylhydrazine affects the expression of LDLR mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LDLR mRNA CTD PMID:22206623 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression ISO RGD:2998 6480464 chlorcyclizine results in increased expression of LDLR mRNA CTD PMID:21058326 1-naphthyl isothiocyanate increases expression ISO RGD:2998 6480464 1-Naphthylisothiocyanate results in increased expression of LDLR mRNA CTD PMID:30723492 11-dehydro-thromboxane B2 multiple interactions ISO RGD:735594 6480464 Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] more ... CTD PMID:20530721 17alpha-ethynylestradiol multiple interactions ISO RGD:735594 6480464 [Desogestrel co-treated with Ethinyl Estradiol] results in increased expression of LDLR protein, [Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein CTD PMID:17900441 17alpha-ethynylestradiol increases expression ISO RGD:2998 6480464 Ethinyl Estradiol results in increased expression of LDLR mRNA, Ethinyl Estradiol results in increased expression of LDLR protein CTD PMID:12475377 more ... 17alpha-ethynylestradiol affects expression ISO RGD:2998 6480464 Ethinyl Estradiol affects the expression of LDLR mRNA CTD PMID:17351261 17alpha-ethynylestradiol increases expression ISO RGD:735594 6480464 Ethinyl Estradiol results in increased expression of LDLR protein CTD PMID:17900441 17beta-estradiol increases expression ISO RGD:735594 6480464 Estradiol results in increased expression of LDLR mRNA CTD PMID:19167446 , PMID:32387340 17beta-estradiol increases expression ISO RGD:2998 6480464 Estradiol results in increased expression of LDLR mRNA CTD PMID:32145629 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one affects localization ISO RGD:735594 6480464 Metribolone affects the localization of LDLR protein CTD PMID:17440980 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:735594 6480464 Dihydrotestosterone results in increased expression of LDLR mRNA CTD PMID:29581250 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:735594 6480464 2 more ... CTD PMID:31173147 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2998 6480464 Tetrachlorodibenzodioxin results in decreased expression of LDLR mRNA CTD PMID:21215274 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2998 6480464 Tetrachlorodibenzodioxin results in increased expression of LDLR mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:2998 6480464 Tetrachlorodibenzodioxin affects the expression of LDLR mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin affects the methylation of LDLR intron] which results in decreased expression of LDLR mRNA, [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LDLR mRNA CTD PMID:25975270 , PMID:33017471 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of LDLR mRNA CTD PMID:22539624 , PMID:22977169 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of LDLR mRNA CTD PMID:21570461 more ... 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:2998 6480464 2 more ... CTD PMID:32109520 2-bromohexadecanoic acid increases expression ISO RGD:735594 6480464 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 2-butoxyethanol increases expression EXP 6480464 n-butoxyethanol results in increased expression of LDLR mRNA CTD PMID:19812364 2-methylcholine affects expression ISO RGD:735594 6480464 beta-methylcholine affects the expression of LDLR mRNA CTD PMID:21179406 22-Hydroxycholesterol decreases expression ISO RGD:735594 6480464 22-hydroxycholesterol results in decreased expression of LDLR mRNA CTD PMID:16142410 25-hydroxycholesterol multiple interactions ISO RGD:735594 6480464 25-hydroxycholesterol inhibits the reaction [[Resveratrol results in increased activity of and results in increased cleavage of SREBF2 protein] which results in increased expression of LDLR mRNA] more ... CTD PMID:12477733 , PMID:22153697 25-hydroxycholesterol decreases expression ISO RGD:735594 6480464 25-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:27447558 25-hydroxycholesterol decreases expression EXP 6480464 25-hydroxycholesterol results in decreased expression of LDLR mRNA, 25-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:19260826 26-hydroxycholesterol decreases activity ISO RGD:735594 6480464 27-hydroxycholesterol results in decreased activity of LDLR protein CTD PMID:8820113 26-hydroxycholesterol decreases expression ISO RGD:2998 6480464 27-hydroxycholesterol results in decreased expression of LDLR mRNA, 27-hydroxycholesterol results in decreased expression of LDLR protein CTD PMID:28167099 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:2998 6480464 3 more ... CTD PMID:23196670 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:735594 6480464 3 more ... CTD PMID:35618242 3,3',4,4',5-pentachlorobiphenyl increases response to substance EXP 6480464 LDLR gene mutant form results in increased susceptibility to 3 more ... CTD PMID:29216392 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:735594 6480464 Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA], desethylamiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] CTD PMID:9712728 3,3',5-triiodo-L-thyronine increases expression ISO RGD:2998 6480464 Triiodothyronine results in increased expression of LDLR mRNA CTD PMID:9071962 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:2998 6480464 Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein] CTD PMID:9071962 3,3',5-triiodo-L-thyronine increases expression ISO RGD:735594 6480464 Triiodothyronine results in increased expression of LDLR mRNA CTD PMID:9712728 3-chloropropane-1,2-diol decreases expression ISO RGD:2998 6480464 alpha-Chlorohydrin results in decreased expression of LDLR mRNA CTD PMID:28522335 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of LDLR mRNA CTD PMID:35487396 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of LDLR mRNA CTD PMID:33297965 4-hydroxy-TEMPO multiple interactions ISO RGD:735594 6480464 tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] CTD PMID:20530721 4-hydroxyphenyl retinamide decreases expression ISO RGD:735594 6480464 Fenretinide results in decreased expression of LDLR mRNA CTD PMID:15958647 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of LDLR mRNA CTD PMID:28973697 6-propyl-2-thiouracil decreases expression ISO RGD:2998 6480464 Propylthiouracil results in decreased expression of LDLR mRNA CTD PMID:24780913 , PMID:25825206 8-Br-cAMP increases expression ISO RGD:735594 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LDLR mRNA CTD PMID:22079614 acetamide decreases expression ISO RGD:2998 6480464 acetamide results in decreased expression of LDLR mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions ISO RGD:735594 6480464 Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] more ... CTD PMID:10395027 , PMID:20530721 acetylsalicylic acid multiple interactions EXP 6480464 Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] CTD PMID:20530721 acrolein multiple interactions ISO RGD:735594 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of LDLR mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of LDLR mRNA CTD PMID:32699268 acrylamide multiple interactions EXP 6480464 Acrylamide inhibits the reaction [Streptozocin results in decreased expression of LDLR mRNA] CTD PMID:34896238 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of LDLR mRNA CTD PMID:34896238 actinomycin D decreases expression ISO RGD:735594 6480464 Dactinomycin results in decreased expression of LDLR mRNA CTD PMID:32913121 actinomycin D multiple interactions ISO RGD:735594 6480464 Ascorbic Acid inhibits the reaction [Dactinomycin results in decreased expression of LDLR mRNA] CTD PMID:32913121 aflatoxin B1 affects expression ISO RGD:735594 6480464 Aflatoxin B1 affects the expression of LDLR protein CTD PMID:20106945 albuterol affects response to substance ISO RGD:735594 6480464 LDLR gene SNP affects the susceptibility to Albuterol CTD PMID:15453913 aldehydo-D-glucose multiple interactions EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 all-trans-retinoic acid increases expression ISO RGD:735594 6480464 Tretinoin results in increased expression of LDLR mRNA CTD PMID:15894607 alpha-pinene multiple interactions ISO RGD:735594 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of LDLR mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of LDLR mRNA CTD PMID:32699268 amiodarone multiple interactions ISO RGD:735594 6480464 Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] CTD PMID:9712728 amiodarone decreases expression ISO RGD:2998 6480464 Amiodarone results in decreased expression of LDLR mRNA, Amiodarone results in decreased expression of LDLR protein CTD PMID:12538616 more ... amiodarone decreases expression ISO RGD:735594 6480464 Amiodarone results in decreased expression of LDLR mRNA CTD PMID:9712728 amiodarone multiple interactions ISO RGD:2998 6480464 Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein] CTD PMID:9071962 ammonium chloride affects expression ISO RGD:2998 6480464 Ammonium Chloride affects the expression of LDLR mRNA CTD PMID:16483693 amphotericin B multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 ampicillin multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:735594 6480464 pyrazolanthrone inhibits the reaction [Quercetin results in increased expression of LDLR mRNA], pyrazolanthrone inhibits the reaction [Quercetin results in increased expression of LDLR protein] CTD PMID:22388943 arachidonic acid multiple interactions ISO RGD:735594 6480464 Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] more ... CTD PMID:20530721 arachidonic acid decreases response to substance EXP 6480464 LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid CTD PMID:20530721 arachidonic acid multiple interactions EXP 6480464 Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] more ... CTD PMID:20530721 Archazolid B increases expression ISO RGD:735594 6480464 archazolid B results in increased expression of LDLR mRNA CTD PMID:25218289 argatroban multiple interactions EXP 6480464 argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol], argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides] CTD PMID:22841818 arsane affects methylation ISO RGD:735594 6480464 Arsenic affects the methylation of LDLR gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:735594 6480464 Arsenic affects the methylation of LDLR gene CTD PMID:25304211 atazanavir sulfate multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of LDLR mRNA CTD PMID:33819548 atorvastatin calcium increases activity ISO RGD:735594 6480464 Atorvastatin results in increased activity of LDLR protein CTD PMID:11728391 , PMID:12612140 atorvastatin calcium multiple interactions ISO RGD:2998 6480464 Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA], Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of LDLR mRNA] CTD PMID:30273964 , PMID:32048413 atorvastatin calcium increases expression ISO RGD:2998 6480464 Atorvastatin results in increased expression of LDLR mRNA CTD PMID:24502637 atorvastatin calcium increases expression ISO RGD:735594 6480464 Atorvastatin results in increased expression of LDLR mRNA CTD PMID:10357840 , PMID:11728391 atrazine affects response to substance ISO RGD:735594 6480464 LDLR gene SNP affects the susceptibility to Atrazine CTD PMID:22919386 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of LDLR mRNA CTD PMID:26518232 aucubin multiple interactions EXP 6480464 aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA] more ... CTD PMID:36108984 avobenzone increases expression ISO RGD:735594 6480464 avobenzone results in increased expression of LDLR mRNA CTD PMID:31016361 Azaspiracid increases expression ISO RGD:735594 6480464 azaspiracid results in increased expression of LDLR mRNA CTD PMID:28939011 azoxystrobin affects expression ISO RGD:735594 6480464 azoxystrobin affects the expression of LDLR mRNA CTD PMID:33512557 bathocuproine disulfonic acid multiple interactions ISO RGD:735594 6480464 bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of LDLR mRNA] CTD PMID:24170205 benzalkonium chloride increases expression EXP 6480464 Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 benzo[a]pyrene decreases expression ISO RGD:735594 6480464 Benzo(a)pyrene results in decreased expression of LDLR mRNA CTD PMID:20064835 , PMID:32234424 benzo[a]pyrene affects expression EXP 6480464 Benzo(a)pyrene affects the expression of LDLR protein CTD PMID:30664314 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:735594 6480464 7 more ... CTD PMID:19150397 berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of LDLR mRNA], Berberine inhibits the reaction [Risperidone results in increased expression of LDLR mRNA] CTD PMID:20564506 berberine increases expression ISO RGD:2998 6480464 Berberine results in increased expression of LDLR mRNA CTD PMID:18640378 berberine multiple interactions ISO RGD:2998 6480464 Berberine promotes the reaction [Simvastatin results in increased expression of LDLR mRNA], Simvastatin promotes the reaction [Berberine results in increased expression of LDLR mRNA] CTD PMID:18640378 bicalutamide affects localization ISO RGD:735594 6480464 bicalutamide affects the localization of LDLR protein CTD PMID:17440980 bifenthrin decreases expression EXP 6480464 bifenthrin results in decreased expression of LDLR mRNA CTD PMID:24449165 , PMID:32408700 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:2998 6480464 Diethylhexyl Phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 , PMID:33983380 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of LDLR mRNA CTD PMID:27405655 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:2998 6480464 [Clofibrate co-treated with Diethylhexyl Phthalate] results in increased expression of LDLR mRNA CTD PMID:9207284 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of LDLR protein CTD PMID:25270622 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LDLR mRNA CTD PMID:23704952 , PMID:25270620 bisphenol A multiple interactions EXP 6480464 [LDLR protein affects the susceptibility to bisphenol A] which affects the expression of APOA1 mRNA CTD PMID:31842455 bisphenol A affects response to substance EXP 6480464 LDLR protein affects the susceptibility to bisphenol A CTD PMID:31842455 bisphenol A decreases expression ISO RGD:735594 6480464 bisphenol A analog results in decreased expression of LDLR mRNA CTD PMID:32387340 bisphenol A affects expression ISO RGD:2998 6480464 bisphenol A affects the expression of LDLR mRNA CTD PMID:30903817 bisphenol A affects expression ISO RGD:735594 6480464 bisphenol A affects the expression of LDLR mRNA CTD PMID:30903817 bisphenol A decreases expression ISO RGD:2998 6480464 bisphenol A results in decreased expression of LDLR mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:2998 6480464 bisphenol A results in increased expression of LDLR mRNA CTD PMID:25181051 , PMID:32145629 bisphenol A increases expression ISO RGD:735594 6480464 bisphenol A results in increased expression of LDLR mRNA CTD PMID:25047013 more ... bromobenzene decreases expression ISO RGD:2998 6480464 bromobenzene results in decreased expression of LDLR mRNA CTD PMID:32479839 butan-1-ol multiple interactions ISO RGD:735594 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LDLR mRNA CTD PMID:29432896 Butylbenzyl phthalate decreases expression ISO RGD:2998 6480464 butylbenzyl phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 cadmium atom decreases expression ISO RGD:735594 6480464 Cadmium results in decreased expression of LDLR mRNA CTD PMID:12080015 cadmium dichloride increases expression ISO RGD:2998 6480464 Cadmium Chloride results in increased expression of LDLR mRNA CTD PMID:33453195 caffeine multiple interactions ISO RGD:2998 6480464 [Caffeine co-treated with Dietary Fats] results in decreased expression of LDLR mRNA, Caffeine promotes the reaction [Dietary Fats results in decreased expression of LDLR mRNA] CTD PMID:29800656 caffeine decreases phosphorylation ISO RGD:735594 6480464 Caffeine results in decreased phosphorylation of LDLR protein CTD PMID:35688186 calciol multiple interactions ISO RGD:2998 6480464 [Cholecalciferol co-treated with Dietary Fats co-treated with Particulate Matter] results in increased expression of LDLR mRNA CTD PMID:36603807 calcitriol increases expression ISO RGD:735594 6480464 Calcitriol results in increased expression of LDLR mRNA CTD PMID:26485663 captan increases expression EXP 6480464 Captan results in increased expression of LDLR mRNA CTD PMID:31558096 carbamazepine decreases expression ISO RGD:735594 6480464 Carbamazepine results in decreased expression of LDLR mRNA CTD PMID:21123845 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of LDLR mRNA CTD PMID:22634333 carbofuran affects response to substance ISO RGD:735594 6480464 LDLR gene SNP affects the susceptibility to Carbofuran CTD PMID:22919386 carbon nanotube increases expression ISO RGD:735594 6480464 Nanotubes, Carbon results in increased expression of LDLR mRNA CTD PMID:24389112 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of LDLR mRNA CTD PMID:25554681 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25448806 , PMID:25620056 carmustine affects uptake ISO RGD:735594 6480464 LDLR protein affects the uptake of Carmustine analog CTD PMID:12107554 celastrol increases expression ISO RGD:735594 6480464 celastrol results in increased expression of LDLR mRNA CTD PMID:17010675 chenodeoxycholic acid multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 chlordecone increases expression EXP 6480464 Chlordecone results in increased expression of LDLR mRNA CTD PMID:29980752 chloroquine multiple interactions EXP 6480464 Chloroquine affects the reaction [SORT1 protein affects the reaction [LDLR protein affects the abundance of Cholesterol]] CTD PMID:30950489 chlorpromazine increases expression ISO RGD:735594 6480464 Chlorpromazine results in increased expression of LDLR mRNA CTD PMID:17052361 cholesterol increases uptake ISO RGD:735594 6480464 LDLR protein results in increased uptake of Cholesterol CTD PMID:16477808 cholesterol affects abundance EXP 6480464 LDLR protein affects the abundance of Cholesterol CTD PMID:30950489 cholesterol increases response to substance EXP 6480464 LDLR gene mutant form results in increased susceptibility to Cholesterol CTD PMID:25263595 cholesterol multiple interactions EXP 6480464 (+)-JQ1 compound inhibits the reaction [LDLR gene mutant form results in increased susceptibility to Cholesterol] more ... CTD PMID:22659316 more ... cholesterol decreases expression ISO RGD:2998 6480464 Cholesterol results in decreased expression of LDLR mRNA CTD PMID:16271152 more ... cholesterol multiple interactions ISO RGD:2998 6480464 [Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA more ... CTD PMID:16937255 more ... cholesterol multiple interactions ISO RGD:735594 6480464 [CYP27A1 protein results in increased chemical synthesis of Bile Acids and Salts] promotes the reaction [LDLR protein results in increased uptake of Cholesterol] more ... CTD PMID:12477733 , PMID:16477808 cholesterol decreases activity ISO RGD:2998 6480464 Cholesterol results in decreased activity of LDLR protein CTD PMID:16271152 more ... cholic acid multiple interactions ISO RGD:2998 6480464 [Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA more ... CTD PMID:30273964 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of LDLR mRNA CTD PMID:20938992 chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of LDLR mRNA CTD PMID:28472532 chromium(6+) decreases expression ISO RGD:735594 6480464 chromium hexavalent ion results in decreased expression of LDLR mRNA CTD PMID:30690063 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of LDLR mRNA CTD PMID:18353800 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of LDLR mRNA CTD PMID:21151649 cisplatin decreases expression ISO RGD:735594 6480464 Cisplatin results in decreased expression of LDLR mRNA CTD PMID:27594783 cisplatin multiple interactions ISO RGD:735594 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of LDLR mRNA, Cisplatin inhibits the reaction [Piroxicam results in decreased expression of LDLR mRNA] CTD PMID:21858171 , PMID:27392435 clofibrate decreases expression ISO RGD:2998 6480464 Clofibrate results in decreased expression of LDLR mRNA CTD PMID:17126302 clofibrate multiple interactions ISO RGD:2998 6480464 [Clofibrate co-treated with Diethylhexyl Phthalate] results in increased expression of LDLR mRNA CTD PMID:9207284 clozapine increases expression EXP 6480464 Clozapine results in increased expression of LDLR mRNA CTD PMID:20564506 clozapine increases expression ISO RGD:735594 6480464 Clozapine results in increased expression of LDLR mRNA CTD PMID:17052361 clozapine multiple interactions EXP 6480464 Berberine inhibits the reaction [Clozapine results in increased expression of LDLR mRNA] CTD PMID:20564506 cobalt dichloride decreases expression ISO RGD:735594 6480464 cobaltous chloride results in decreased expression of LDLR mRNA CTD PMID:19320972 cobalt dichloride increases expression ISO RGD:735594 6480464 cobaltous chloride results in increased expression of LDLR mRNA CTD PMID:19376846 colesevelam hydrochloride increases expression EXP 6480464 Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 copper atom decreases expression ISO RGD:735594 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper atom decreases expression ISO RGD:2998 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:30556269 copper atom decreases expression EXP 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper(0) decreases expression ISO RGD:735594 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper(0) decreases expression ISO RGD:2998 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:30556269 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of LDLR mRNA CTD PMID:17205981 copper(II) sulfate increases expression ISO RGD:735594 6480464 Copper Sulfate results in increased expression of LDLR mRNA CTD PMID:12860252 , PMID:19549813 cortisol multiple interactions ISO RGD:735594 6480464 Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of LDLR mRNA] CTD PMID:31075344 cortisol decreases expression ISO RGD:735594 6480464 Hydrocortisone results in decreased expression of LDLR mRNA CTD PMID:31075344 coumestrol multiple interactions ISO RGD:735594 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LDLR mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO RGD:735594 6480464 Asbestos, Crocidolite results in increased expression of LDLR mRNA CTD PMID:25351596 crocin-1 multiple interactions ISO RGD:2998 6480464 crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 curcumin multiple interactions ISO RGD:735594 6480464 Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA], Curcumin results in increased expression of and results in increased activity of LDLR protein CTD PMID:18704882 curcumin affects expression EXP 6480464 Curcumin affects the expression of LDLR mRNA CTD PMID:27208389 curcumin increases expression ISO RGD:735594 6480464 Curcumin results in increased expression of LDLR mRNA, Curcumin results in increased expression of LDLR protein CTD PMID:16713233 more ... cycloheximide multiple interactions ISO RGD:735594 6480464 Cycloheximide inhibits the reaction [Quercetin results in increased expression of LDLR protein] CTD PMID:22388943 cycloheximide decreases expression ISO RGD:735594 6480464 Cycloheximide results in decreased expression of LDLR protein CTD PMID:22388943 cyclosporin A multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in increased expression of LDLR mRNA more ... CTD PMID:10395027 , PMID:33819548 cyclosporin A increases expression ISO RGD:735594 6480464 Cyclosporine results in increased expression of LDLR mRNA CTD PMID:20106945 more ... cyproconazole affects expression EXP 6480464 cyproconazole affects the expression of LDLR mRNA CTD PMID:22045034 D-glucose multiple interactions EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 DDE decreases expression ISO RGD:2998 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of LDLR mRNA CTD PMID:15885261 deoxycholic acid multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 desmosterol decreases expression EXP 6480464 Desmosterol results in decreased expression of LDLR protein CTD PMID:19260826 desogestrel multiple interactions ISO RGD:735594 6480464 [Desogestrel co-treated with Ethinyl Estradiol] results in increased expression of LDLR protein CTD PMID:17900441 desogestrel increases expression ISO RGD:735594 6480464 Desogestrel results in increased expression of LDLR protein CTD PMID:17900441 dexamethasone increases expression ISO RGD:735594 6480464 Dexamethasone results in increased expression of LDLR mRNA CTD PMID:25047013 dexamethasone decreases expression ISO RGD:735594 6480464 Dexamethasone results in decreased expression of LDLR mRNA, Dexamethasone results in decreased expression of LDLR protein CTD PMID:32234517 dexamethasone decreases expression ISO RGD:2998 6480464 Dexamethasone results in decreased expression of LDLR mRNA, Dexamethasone results in decreased expression of LDLR protein CTD PMID:32234517 dexamethasone multiple interactions ISO RGD:735594 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of LDLR mRNA] more ... CTD PMID:32234517 Di-n-hexyl phthalate decreases expression ISO RGD:2998 6480464 di-n-hexyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 diazinon multiple interactions ISO RGD:2998 6480464 crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 diazinon decreases expression ISO RGD:2998 6480464 Diazinon results in decreased expression of LDLR mRNA CTD PMID:24132704 dibenzo[a,l]pyrene decreases expression ISO RGD:735594 6480464 dibenzo(a, l)pyrene results in decreased expression of LDLR mRNA CTD PMID:16269432 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of LDLR mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO RGD:2998 6480464 Dibutyl Phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 more ... dicrotophos increases expression ISO RGD:735594 6480464 dicrotophos results in increased expression of LDLR mRNA CTD PMID:28302478 Dicyclohexyl phthalate decreases expression ISO RGD:2998 6480464 dicyclohexyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 dieldrin increases expression ISO RGD:735594 6480464 Dieldrin results in increased expression of LDLR mRNA CTD PMID:31068361 diethyl maleate decreases expression ISO RGD:2998 6480464 diethyl maleate results in decreased expression of LDLR mRNA CTD PMID:21161181 diisobutyl phthalate decreases expression ISO RGD:2998 6480464 diisobutyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 diisononyl phthalate decreases expression ISO RGD:2998 6480464 diisononyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 dimethylarsinic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 dinophysistoxin 1 increases expression ISO RGD:735594 6480464 dinophysistoxin 1 results in increased expression of LDLR mRNA CTD PMID:28939011 dioxygen multiple interactions ISO RGD:2998 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of LDLR mRNA CTD PMID:33729688 dipentyl phthalate decreases expression ISO RGD:2998 6480464 di-n-pentyl phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 , PMID:33983380 disodium selenite multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] CTD PMID:36464106 diuron decreases expression ISO RGD:735594 6480464 Diuron results in decreased expression of LDLR mRNA CTD PMID:35967413 dorsomorphin multiple interactions ISO RGD:735594 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LDLR mRNA CTD PMID:27188386 doxorubicin decreases expression ISO RGD:735594 6480464 Doxorubicin results in decreased expression of LDLR mRNA CTD PMID:29803840 elemental selenium multiple interactions ISO RGD:2998 6480464 Selenium inhibits the reaction [Cholesterol results in decreased activity of LDLR protein], Selenium inhibits the reaction [Cholesterol results in decreased expression of LDLR mRNA] CTD PMID:16937255 elemental selenium multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] CTD PMID:36464106 elemental selenium increases expression ISO RGD:2998 6480464 Selenium results in increased expression of LDLR mRNA CTD PMID:16271152 elemental selenium increases activity ISO RGD:2998 6480464 Selenium results in increased activity of LDLR protein CTD PMID:16271152 elemental selenium decreases activity ISO RGD:2998 6480464 Selenium deficiency results in decreased activity of LDLR protein CTD PMID:16317514 elemental selenium decreases expression ISO RGD:2998 6480464 Selenium deficiency results in decreased expression of LDLR mRNA CTD PMID:16317514 endosulfan affects expression ISO RGD:2998 6480464 Endosulfan affects the expression of LDLR mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO RGD:735594 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LDLR mRNA CTD PMID:19167446 epoxiconazole increases expression ISO RGD:2998 6480464 epoxiconazole results in increased expression of LDLR mRNA CTD PMID:28454766 epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of LDLR mRNA CTD PMID:35436446 ethanol increases expression ISO RGD:2998 6480464 Ethanol results in increased expression of LDLR mRNA CTD PMID:15353170 ethanol affects expression EXP 6480464 Ethanol affects the expression of LDLR mRNA CTD PMID:30319688 ethanol increases expression EXP 6480464 Ethanol results in increased expression of LDLR mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:735594 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LDLR mRNA more ... CTD PMID:29432896 , PMID:31226463 ethanol decreases expression ISO RGD:735594 6480464 Ethanol results in decreased expression of LDLR mRNA, Ethanol results in decreased expression of LDLR protein CTD PMID:31226463 ethanol decreases expression ISO RGD:2998 6480464 Ethanol results in decreased expression of LDLR mRNA, Ethanol results in decreased expression of LDLR protein CTD PMID:31075344 , PMID:31226463 ethyl methanesulfonate decreases expression ISO RGD:735594 6480464 Ethyl Methanesulfonate results in decreased expression of LDLR mRNA CTD PMID:23649840 ezetimibe multiple interactions ISO RGD:735594 6480464 [Simvastatin co-treated with Ezetimibe] results in increased expression of LDLR mRNA CTD PMID:17980884 fenthion increases expression EXP 6480464 Fenthion results in increased expression of LDLR mRNA CTD PMID:34813904 flufenamic acid multiple interactions ISO RGD:735594 6480464 Flufenamic Acid inhibits the reaction [Cyclosporine inhibits the reaction [[Cholesterol more ... CTD PMID:10395027 flufenamic acid increases expression ISO RGD:735594 6480464 Flufenamic Acid results in increased expression of LDLR mRNA, Flufenamic Acid results in increased expression of LDLR protein CTD PMID:10395027 fluoranthene decreases expression EXP 6480464 fluoranthene results in decreased expression of LDLR mRNA CTD PMID:28329830 fluoranthene multiple interactions EXP 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of LDLR mRNA CTD PMID:28329830 flusilazole affects expression EXP 6480464 flusilazole affects the expression of LDLR mRNA CTD PMID:21195148 , PMID:22634333 flutamide decreases expression ISO RGD:2998 6480464 Flutamide results in decreased expression of LDLR mRNA CTD PMID:15885261 fluvastatin multiple interactions ISO RGD:735594 6480464 [APOB gene SNP co-treated with APOE gene SNP co-treated with HMGCR gene SNP co-treated with LDLR gene SNP co-treated with PCSK9 gene SNP co-treated with ABCA1 gene SNP co-treated with CETP gene SNP co-treated with LIPC gene SNP co-treated with LPL gene SNP] affects the susceptibility to fluvastatin more ... CTD PMID:10395027 , PMID:19773416 fluvastatin increases activity ISO RGD:735594 6480464 fluvastatin results in increased activity of LDLR protein CTD PMID:8593127 folic acid multiple interactions EXP 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 folic acid decreases expression ISO RGD:735594 6480464 Folic Acid results in decreased expression of LDLR mRNA CTD PMID:21867686 formaldehyde decreases expression ISO RGD:735594 6480464 Formaldehyde results in decreased expression of LDLR mRNA CTD PMID:23649840 gallic acid increases expression ISO RGD:735594 6480464 Gallic Acid results in increased expression of LDLR mRNA CTD PMID:12612140 Ganoderic acid A decreases expression ISO RGD:735594 6480464 ganoderic acid A results in decreased expression of LDLR mRNA CTD PMID:29852127 Ganoderic acid A multiple interactions EXP 6480464 [Dietary Fats co-treated with ganoderic acid A] affects the expression of LDLR mRNA CTD PMID:29852127 gedunin increases expression ISO RGD:735594 6480464 gedunin results in increased expression of LDLR mRNA CTD PMID:17010675 genistein increases expression EXP 6480464 Genistein results in increased expression of LDLR mRNA CTD PMID:32186404 geraniol increases expression EXP 6480464 geraniol results in increased expression of LDLR mRNA CTD PMID:26141755 Ginsenoside Rh4 multiple interactions EXP 6480464 ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA] CTD PMID:33359794 glucose multiple interactions EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 glycochenodeoxycholic acid multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:33819548 graphene oxide increases expression EXP 6480464 graphene oxide results in increased expression of LDLR mRNA CTD PMID:33227293 GW 3965 decreases expression ISO RGD:735594 6480464 GW 3965 results in decreased expression of LDLR protein CTD PMID:27598782 haloperidol increases expression ISO RGD:735594 6480464 Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 hexaconazole affects expression EXP 6480464 hexaconazole affects the expression of LDLR mRNA CTD PMID:21195148 hexadecanoic acid multiple interactions ISO RGD:735594 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA CTD PMID:30547786 hydrazine increases expression EXP 6480464 hydrazine results in increased expression of LDLR mRNA CTD PMID:15282401 hydrogen peroxide increases expression ISO RGD:735594 6480464 Hydrogen Peroxide results in increased expression of LDLR mRNA CTD PMID:12414654 hydrogen peroxide multiple interactions EXP 6480464 Metformin inhibits the reaction [Hydrogen Peroxide results in increased expression of LDLR protein] CTD PMID:29499335 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of LDLR protein CTD PMID:29499335 hydrogen peroxide multiple interactions ISO RGD:735594 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 ibuprofen multiple interactions ISO RGD:735594 6480464 Ibuprofen promotes the reaction [[Cholesterol more ... CTD PMID:10395027 indometacin multiple interactions EXP 6480464 Indomethacin promotes the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] CTD PMID:20530721 indometacin increases expression ISO RGD:735594 6480464 Indomethacin results in increased expression of LDLR mRNA, Indomethacin results in increased expression of LDLR protein CTD PMID:10395027 indometacin multiple interactions ISO RGD:735594 6480464 fluvastatin promotes the reaction [Indomethacin promotes the reaction [Cholesterol more ... CTD PMID:10395027 isobutanol multiple interactions ISO RGD:735594 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LDLR mRNA CTD PMID:29432896 isoflavones affects expression ISO RGD:735594 6480464 Isoflavones affects the expression of LDLR mRNA CTD PMID:16365062 isotretinoin decreases expression ISO RGD:735594 6480464 Isotretinoin results in decreased expression of LDLR mRNA CTD PMID:20436886 L-ascorbic acid multiple interactions ISO RGD:735594 6480464 Ascorbic Acid inhibits the reaction [Dactinomycin results in decreased expression of LDLR mRNA] more ... CTD PMID:32913121 L-ascorbic acid increases expression ISO RGD:735594 6480464 Ascorbic Acid results in increased expression of LDLR mRNA, Ascorbic Acid results in increased expression of LDLR protein CTD PMID:32913121 L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of LDLR mRNA, Ascorbic Acid results in increased expression of LDLR protein CTD PMID:32913121 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid affects the reaction [GULO protein affects the expression of LDLR protein] CTD PMID:32913121 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of LDLR mRNA CTD PMID:20938992 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of LDLR mRNA CTD PMID:25270620 lead diacetate decreases expression ISO RGD:2998 6480464 lead acetate results in decreased expression of LDLR mRNA, lead acetate results in decreased expression of LDLR protein CTD PMID:29908845 lead(0) affects expression ISO RGD:2998 6480464 Lead affects the expression of LDLR CTD PMID:22001170 lead(0) increases localization ISO RGD:2998 6480464 Lead results in increased localization of LDLR protein CTD PMID:20488202 lead(0) multiple interactions ISO RGD:2998 6480464 PRKCD protein promotes the reaction [Lead results in increased localization of LDLR protein] more ... CTD PMID:20488202 , PMID:22001170 leflunomide decreases expression EXP 6480464 leflunomide results in decreased expression of LDLR mRNA CTD PMID:19751817 leflunomide increases expression ISO RGD:735594 6480464 leflunomide results in increased expression of LDLR mRNA CTD PMID:28988120 levonorgestrel affects expression ISO RGD:735594 6480464 Levonorgestrel affects the expression of LDLR protein CTD PMID:17900441 levonorgestrel multiple interactions ISO RGD:735594 6480464 [Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein CTD PMID:17900441 lipopolysaccharide multiple interactions ISO RGD:2998 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in increased expression of LDLR protein], SREBF2 protein affects the reaction [Lipopolysaccharides results in increased expression of LDLR protein] CTD PMID:33677747 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of LDLR mRNA CTD PMID:12057914 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of LDLR mRNA, Lipopolysaccharides results in decreased expression of LDLR protein CTD PMID:18638454 lipopolysaccharide increases expression ISO RGD:2998 6480464 Lipopolysaccharides results in increased expression of LDLR protein CTD PMID:33677747 lipopolysaccharide increases expression ISO RGD:735594 6480464 Lipopolysaccharides results in increased expression of LDLR mRNA, Lipopolysaccharides results in increased expression of LDLR protein CTD PMID:33677747 lipopolysaccharide multiple interactions ISO RGD:735594 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of LDLR mRNA more ... CTD PMID:33677747 , PMID:35877022 lithocholic acid decreases expression EXP 6480464 Lithocholic Acid results in decreased expression of LDLR mRNA CTD PMID:20359477 lovastatin multiple interactions ISO RGD:735594 6480464 OSM protein promotes the reaction [Lovastatin results in increased expression of LDLR mRNA] CTD PMID:12524230 lovastatin multiple interactions EXP 6480464 [Dietary Fats co-treated with Lovastatin] affects the expression of LDLR mRNA CTD PMID:29852127 lovastatin multiple interactions ISO RGD:2998 6480464 [Cholesterol deficiency co-treated with Lovastatin] results in increased expression of LDLR mRNA, Cholesterol inhibits the reaction [[Cholesterol deficiency co-treated with Lovastatin] results in increased expression of LDLR mRNA] CTD PMID:20578043 lovastatin increases activity ISO RGD:735594 6480464 Lovastatin results in increased activity of LDLR protein CTD PMID:11728391 , PMID:8593127 lovastatin increases expression ISO RGD:735594 6480464 Lovastatin results in increased expression of LDLR mRNA CTD PMID:11728391 , PMID:12524230 lycopene increases expression ISO RGD:735594 6480464 lycopene results in increased expression of LDLR mRNA CTD PMID:16886892 menadione increases expression ISO RGD:735594 6480464 Vitamin K 3 results in increased expression of LDLR mRNA CTD PMID:12414654 metformin multiple interactions ISO RGD:735594 6480464 Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] CTD PMID:29499335 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [AGT protein results in increased expression of LDLR protein], Metformin inhibits the reaction [Hydrogen Peroxide results in increased expression of LDLR protein] CTD PMID:29499335 methyl methanesulfonate decreases expression ISO RGD:735594 6480464 Methyl Methanesulfonate results in decreased expression of LDLR mRNA CTD PMID:23649840 methylarsonic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 methylmercury chloride increases expression ISO RGD:735594 6480464 methylmercuric chloride results in increased expression of LDLR mRNA CTD PMID:28001369 metronidazole multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of LDLR mRNA CTD PMID:25497113 mifepristone multiple interactions ISO RGD:735594 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of LDLR mRNA] more ... CTD PMID:31075344 , PMID:32234517 mitogen increases expression EXP 6480464 Mitogens results in increased expression of LDLR protein CTD PMID:30664314 monocrotophos increases expression ISO RGD:2998 6480464 Monocrotophos results in increased expression of LDLR mRNA CTD PMID:32267039 monosodium L-glutamate multiple interactions EXP 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of LDLR mRNA CTD PMID:19001666 N-desethylamiodarone decreases expression ISO RGD:735594 6480464 desethylamiodarone results in decreased expression of LDLR mRNA CTD PMID:9712728 N-desethylamiodarone multiple interactions ISO RGD:735594 6480464 desethylamiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] CTD PMID:9712728 nefazodone multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of LDLR mRNA CTD PMID:33819548 neomycin multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 nickel atom increases expression ISO RGD:735594 6480464 Nickel results in increased expression of LDLR mRNA CTD PMID:23195993 , PMID:24768652 nickel dichloride decreases expression ISO RGD:735594 6480464 nickel chloride results in decreased expression of LDLR mRNA CTD PMID:17312168 nicotine increases expression ISO RGD:735594 6480464 Nicotine results in increased expression of LDLR mRNA CTD PMID:23416264 obeticholic acid decreases expression ISO RGD:735594 6480464 obeticholic acid results in decreased expression of LDLR mRNA CTD PMID:27939613 okadaic acid increases expression ISO RGD:735594 6480464 Okadaic Acid results in increased expression of LDLR mRNA CTD PMID:28939011 olanzapine increases expression ISO RGD:735594 6480464 olanzapine results in increased expression of LDLR mRNA CTD PMID:17052361 olanzapine multiple interactions EXP 6480464 olanzapine promotes the reaction [SREBF1 protein results in increased expression of LDLR mRNA] CTD PMID:17651982 oleic acid multiple interactions ISO RGD:735594 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA CTD PMID:30547786 ozone increases expression ISO RGD:2998 6480464 Ozone results in increased expression of LDLR mRNA CTD PMID:16330353 , PMID:29329427 ozone multiple interactions ISO RGD:735594 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of LDLR mRNA more ... CTD PMID:32699268 ozone multiple interactions ISO RGD:2998 6480464 Fish Oils inhibits the reaction [Ozone results in increased expression of LDLR mRNA] CTD PMID:29329427 paclitaxel affects response to substance ISO RGD:735594 6480464 LDLR protein affects the susceptibility to Paclitaxel CTD PMID:16217747 paracetamol multiple interactions ISO RGD:735594 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of LDLR mRNA more ... CTD PMID:10395027 , PMID:33819548 paracetamol decreases expression ISO RGD:2998 6480464 Acetaminophen results in decreased expression of LDLR mRNA CTD PMID:32479839 , PMID:33387578 paracetamol increases expression ISO RGD:735594 6480464 Acetaminophen results in increased expression of LDLR mRNA CTD PMID:21420995 paraquat increases expression ISO RGD:2998 6480464 Paraquat results in increased expression of LDLR mRNA CTD PMID:32680482 perfluorononanoic acid decreases expression ISO RGD:735594 6480464 perfluoro-n-nonanoic acid results in decreased expression of LDLR mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:735594 6480464 perfluorooctane sulfonic acid results in decreased expression of LDLR mRNA CTD PMID:32253466 , PMID:32588087 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LDLR mRNA CTD PMID:36331819 perfluorooctanoic acid increases expression ISO RGD:735594 6480464 perfluorooctanoic acid results in increased expression of LDLR protein CTD PMID:26879310 perfluorooctanoic acid decreases expression ISO RGD:735594 6480464 perfluorooctanoic acid results in decreased expression of LDLR mRNA CTD PMID:32253466 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of LDLR mRNA CTD PMID:26942110 , PMID:32822737 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of LDLR mRNA CTD PMID:17681415 , PMID:25092180 permethrin decreases expression ISO RGD:2998 6480464 Permethrin results in decreased expression of LDLR protein CTD PMID:32911180 Phenelzine decreases expression EXP 6480464 Phenelzine results in decreased expression of LDLR mRNA CTD PMID:31249575 phenobarbital affects expression ISO RGD:735594 6480464 Phenobarbital affects the expression of LDLR mRNA CTD PMID:19159669 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of LDLR mRNA CTD PMID:23091169 phenylephrine increases expression ISO RGD:2998 6480464 Phenylephrine results in increased expression of LDLR mRNA CTD PMID:18158353 phenylmercury acetate decreases expression ISO RGD:735594 6480464 Phenylmercuric Acetate results in decreased expression of LDLR mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:735594 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LDLR mRNA CTD PMID:27188386 phenylpropanolamine increases expression ISO RGD:735594 6480464 Phenylpropanolamine results in increased expression of LDLR mRNA CTD PMID:27756839 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:735594 6480464 Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] CTD PMID:29499335 phorbol 13-acetate 12-myristate increases expression ISO RGD:735594 6480464 Tetradecanoylphorbol Acetate results in increased expression of LDLR mRNA, Tetradecanoylphorbol Acetate results in increased expression of LDLR protein CTD PMID:29499335 , PMID:31068361 phosgene affects expression EXP 6480464 Phosgene affects the expression of LDLR mRNA CTD PMID:16300373 pioglitazone increases expression EXP 6480464 pioglitazone results in increased expression of LDLR protein CTD PMID:22593575 pioglitazone multiple interactions EXP 6480464 [pioglitazone co-treated with U 0126] affects the localization of LDLR protein CTD PMID:22593575 pirinixic acid decreases expression ISO RGD:2998 6480464 pirinixic acid results in decreased expression of LDLR mRNA CTD PMID:17126302 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of LDLR mRNA CTD PMID:23811191 pirinixic acid decreases expression ISO RGD:735594 6480464 pirinixic acid results in decreased expression of LDLR mRNA CTD PMID:23150725 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of LDLR mRNA CTD PMID:25270620 pirinixic acid increases expression ISO RGD:2998 6480464 pirinixic acid results in increased expression of LDLR mRNA CTD PMID:19162173 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of LDLR mRNA CTD PMID:18445702 piroxicam multiple interactions ISO RGD:735594 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of LDLR mRNA] CTD PMID:21858171 piroxicam decreases expression ISO RGD:735594 6480464 Piroxicam results in decreased expression of LDLR mRNA CTD PMID:21858171 potassium chromate multiple interactions ISO RGD:735594 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LDLR mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:735594 6480464 potassium chromate(VI) results in decreased expression of LDLR mRNA CTD PMID:22079256 , PMID:22714537 potassium dichromate increases expression ISO RGD:735594 6480464 Potassium Dichromate results in increased expression of LDLR protein CTD PMID:23718831 pravastatin increases activity ISO RGD:735594 6480464 Pravastatin results in increased activity of LDLR protein CTD PMID:8593127 pravastatin increases response to substance EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] which results in increased susceptibility to INS1 protein, LDLR gene mutant form results in increased susceptibility to Pravastatin CTD PMID:26875785 pravastatin multiple interactions EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] more ... CTD PMID:26875785 proanthocyanidin multiple interactions ISO RGD:2998 6480464 Proanthocyanidins inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased expression of LDLR mRNA] CTD PMID:30273964 progesterone affects expression EXP 6480464 Progesterone affects the expression of LDLR mRNA CTD PMID:17251523 progesterone increases expression ISO RGD:735594 6480464 Progesterone results in increased expression of LDLR mRNA CTD PMID:18037150 , PMID:18070364 progesterone increases expression ISO RGD:2998 6480464 Progesterone results in increased expression of LDLR mRNA CTD PMID:17170212 propamocarb multiple interactions EXP 6480464 propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of LDLR mRNA] CTD PMID:34426332 pterostilbene decreases expression ISO RGD:735594 6480464 pterostilbene results in decreased expression of LDLR mRNA CTD PMID:22153697 puerarin multiple interactions ISO RGD:2998 6480464 puerarin affects the reaction [Lead affects the expression of LDLR] CTD PMID:22001170 puromycin multiple interactions ISO RGD:735594 6480464 Puromycin inhibits the reaction [GW 707 results in increased expression of LDLR mRNA] more ... CTD PMID:12524230 , PMID:22388943 puromycin decreases expression ISO RGD:735594 6480464 Puromycin results in decreased expression of LDLR mRNA, Puromycin results in decreased expression of LDLR protein CTD PMID:22388943 quercetin multiple interactions ISO RGD:735594 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of LDLR mRNA] more ... CTD PMID:22388943 quercetin increases expression ISO RGD:735594 6480464 Quercetin results in increased expression of LDLR mRNA, Quercetin results in increased expression of LDLR protein CTD PMID:21632981 , PMID:22388943 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO RGD:735594 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO RGD:735594 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 raloxifene increases expression ISO RGD:735594 6480464 Raloxifene Hydrochloride results in increased expression of LDLR mRNA CTD PMID:16497877 rebaudioside A multiple interactions EXP 6480464 rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] more ... CTD PMID:25554529 resveratrol multiple interactions ISO RGD:735594 6480464 25-hydroxycholesterol inhibits the reaction [[resveratrol results in increased activity of and results in increased cleavage of SREBF2 protein] which results in increased expression of LDLR mRNA] more ... CTD PMID:22153697 resveratrol multiple interactions ISO RGD:2998 6480464 resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR mRNA], resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR protein] CTD PMID:23127599 resveratrol increases expression ISO RGD:735594 6480464 resveratrol results in increased expression of LDLR mRNA CTD PMID:22153697 resveratrol decreases N-linked glycosylation ISO RGD:735594 6480464 resveratrol results in decreased N-linked glycosylation of LDLR protein CTD PMID:22153697 resveratrol increases O-linked glycosylation ISO RGD:735594 6480464 resveratrol results in increased O-linked glycosylation of LDLR protein CTD PMID:22153697 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of LDLR mRNA CTD PMID:27806127 risperidone multiple interactions EXP 6480464 Berberine inhibits the reaction [Risperidone results in increased expression of LDLR mRNA] CTD PMID:20564506 risperidone increases expression EXP 6480464 Risperidone results in increased expression of LDLR mRNA CTD PMID:20564506 rotenone affects expression ISO RGD:2998 6480464 Rotenone affects the expression of LDLR mRNA CTD PMID:28374803 rottlerin multiple interactions ISO RGD:2998 6480464 rottlerin inhibits the reaction [PRKCD protein promotes the reaction [Lead results in increased localization of LDLR protein]] CTD PMID:20488202 SB 431542 multiple interactions ISO RGD:735594 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LDLR mRNA CTD PMID:27188386 selenium atom multiple interactions ISO RGD:2998 6480464 Selenium inhibits the reaction [Cholesterol results in decreased activity of LDLR protein], Selenium inhibits the reaction [Cholesterol results in decreased expression of LDLR mRNA] CTD PMID:16937255 selenium atom multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA] CTD PMID:36464106 selenium atom increases expression ISO RGD:2998 6480464 Selenium results in increased expression of LDLR mRNA CTD PMID:16271152 selenium atom increases activity ISO RGD:2998 6480464 Selenium results in increased activity of LDLR protein CTD PMID:16271152 selenium atom decreases activity ISO RGD:2998 6480464 Selenium deficiency results in decreased activity of LDLR protein CTD PMID:16317514 selenium atom decreases expression ISO RGD:2998 6480464 Selenium deficiency results in decreased expression of LDLR mRNA CTD PMID:16317514 silicon dioxide affects expression ISO RGD:735594 6480464 Silicon Dioxide analog affects the expression of LDLR mRNA CTD PMID:23806026 silicon dioxide increases expression ISO RGD:735594 6480464 Silicon Dioxide results in increased expression of LDLR mRNA CTD PMID:25351596 silver atom increases expression ISO RGD:735594 6480464 Silver results in increased expression of LDLR mRNA CTD PMID:26014281 silver(0) increases expression ISO RGD:735594 6480464 Silver results in increased expression of LDLR mRNA CTD PMID:26014281 simvastatin multiple interactions ISO RGD:735594 6480464 [LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB more ... CTD PMID:17980884 , PMID:20413733 simvastatin increases expression ISO RGD:735594 6480464 Simvastatin results in increased expression of LDLR mRNA, Simvastatin results in increased expression of LDLR protein CTD PMID:10357840 more ... simvastatin increases activity ISO RGD:735594 6480464 Simvastatin results in increased activity of LDLR protein CTD PMID:11728391 , PMID:8593127 simvastatin increases expression ISO RGD:2998 6480464 Simvastatin results in increased expression of LDLR mRNA CTD PMID:18640378 simvastatin multiple interactions ISO RGD:2998 6480464 Berberine promotes the reaction [Simvastatin results in increased expression of LDLR mRNA], Simvastatin promotes the reaction [Berberine results in increased expression of LDLR mRNA] CTD PMID:18640378 simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of LDLR mRNA CTD PMID:22120639 simvastatin affects response to substance ISO RGD:735594 6480464 LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin, LDLR mutant form affects the susceptibility to Simvastatin CTD PMID:10208479 more ... sodium arsenate multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 sodium arsenite increases expression ISO RGD:735594 6480464 sodium arsenite results in increased expression of LDLR mRNA CTD PMID:25524072 more ... sodium arsenite multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of LDLR mRNA CTD PMID:34876320 sotorasib multiple interactions ISO RGD:735594 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLR mRNA CTD PMID:36139627 steviol multiple interactions EXP 6480464 steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACACA mRNA] more ... CTD PMID:25554529 stevioside multiple interactions EXP 6480464 stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] more ... CTD PMID:25554529 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of LDLR mRNA CTD PMID:34896238 streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA more ... CTD PMID:33359794 , PMID:34896238 sucrose multiple interactions ISO RGD:2998 6480464 [Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR mRNA more ... CTD PMID:23127599 sulindac sulfide decreases expression ISO RGD:735594 6480464 sulindac sulfide results in decreased expression of LDLR mRNA CTD PMID:16184548 sunitinib increases expression ISO RGD:735594 6480464 Sunitinib results in increased expression of LDLR mRNA CTD PMID:31533062 tamoxifen increases expression ISO RGD:735594 6480464 Tamoxifen results in increased expression of LDLR protein CTD PMID:27358406 tamoxifen multiple interactions EXP 6480464 SREBF2 protein promotes the reaction [Tamoxifen results in increased expression of LDLR mRNA], SREBF2 protein promotes the reaction [Tamoxifen results in increased expression of LDLR protein] CTD PMID:35944649 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of LDLR mRNA, Tamoxifen results in increased expression of LDLR protein CTD PMID:35944649 tert-butyl hydroperoxide increases expression ISO RGD:735594 6480464 tert-Butylhydroperoxide results in increased expression of LDLR mRNA CTD PMID:12414654 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of LDLR mRNA CTD PMID:31919559 thapsigargin decreases expression ISO RGD:735594 6480464 Thapsigargin results in decreased expression of LDLR mRNA CTD PMID:22378314 thapsigargin increases expression ISO RGD:2998 6480464 Thapsigargin results in increased expression of LDLR protein CTD PMID:35544339 thapsigargin increases expression ISO RGD:735594 6480464 Thapsigargin results in increased expression of LDLR mRNA CTD PMID:29453283 thioacetamide affects expression ISO RGD:2998 6480464 Thioacetamide affects the expression of LDLR mRNA CTD PMID:34492290 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of LDLR mRNA CTD PMID:23557971 more ... trametinib multiple interactions ISO RGD:735594 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of LDLR mRNA CTD PMID:36139627 triadimefon affects expression EXP 6480464 triadimefon affects the expression of LDLR mRNA CTD PMID:21195148 triadimefon decreases expression ISO RGD:2998 6480464 triadimefon results in decreased expression of LDLR mRNA CTD PMID:36179991 trichloroethene increases expression ISO RGD:2998 6480464 Trichloroethylene results in increased expression of LDLR mRNA CTD PMID:33387578 triphenyl phosphate increases expression ISO RGD:735594 6480464 triphenyl phosphate results in increased expression of LDLR mRNA CTD PMID:28934090 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of LDLR mRNA CTD PMID:26183808 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of LDLR mRNA CTD PMID:26049154 triphenylstannane decreases expression ISO RGD:2998 6480464 triphenyltin results in decreased expression of LDLR mRNA, triphenyltin results in decreased expression of LDLR protein CTD PMID:32504733 triptonide decreases expression EXP 6480464 triptonide results in decreased expression of LDLR mRNA CTD PMID:33045310 tris(2-chloroethyl) phosphate increases expression EXP 6480464 tris(chloroethyl)phosphate results in increased expression of LDLR mRNA CTD PMID:26049154 tris(2-chloroethyl) phosphate decreases expression EXP 6480464 tris(chloroethyl)phosphate results in decreased expression of LDLR mRNA CTD PMID:26183808 troglitazone multiple interactions ISO RGD:735594 6480464 [[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased expression of SREBF2 protein] which results in decreased expression of LDLR mRNA CTD PMID:16946405 troglitazone decreases expression ISO RGD:735594 6480464 troglitazone results in decreased expression of LDLR mRNA CTD PMID:25572481 troglitazone increases activity ISO RGD:735594 6480464 troglitazone results in increased activity of LDLR protein CTD PMID:9703316 troglitazone increases expression ISO RGD:735594 6480464 troglitazone results in increased expression of LDLR mRNA CTD PMID:9703316 trovafloxacin multiple interactions EXP 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of LDLR mRNA CTD PMID:18930950 tunicamycin decreases expression ISO RGD:735594 6480464 Tunicamycin results in decreased expression of LDLR mRNA CTD PMID:22378314 , PMID:29453283 urethane increases expression ISO RGD:735594 6480464 Urethane results in increased expression of LDLR mRNA CTD PMID:28818685 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of LDLR mRNA CTD PMID:17963808 valproic acid affects methylation ISO RGD:735594 6480464 Valproic Acid affects the methylation of LDLR gene CTD PMID:29501571 valproic acid decreases expression ISO RGD:735594 6480464 Valproic Acid results in decreased expression of LDLR mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:735594 6480464 Valproic Acid affects the expression of LDLR mRNA CTD PMID:25979313 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of LDLR mRNA CTD PMID:19136453 , PMID:22045034 vancomycin multiple interactions EXP 6480464 [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA], [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 vinclozolin decreases expression ISO RGD:2998 6480464 vinclozolin results in decreased expression of LDLR mRNA CTD PMID:23034163 vorinostat decreases expression ISO RGD:735594 6480464 vorinostat results in decreased expression of LDLR mRNA CTD PMID:27188386 Yessotoxin increases expression ISO RGD:735594 6480464 yessotoxin analog results in increased expression of LDLR mRNA CTD PMID:30679557 zearalenone increases expression ISO RGD:735594 6480464 Zearalenone results in increased expression of LDLR mRNA CTD PMID:32119988 zearalenone decreases expression ISO RGD:2998 6480464 Zearalenone results in decreased expression of LDLR mRNA, Zearalenone results in decreased expression of LDLR protein CTD PMID:32858132 zinc atom multiple interactions ISO RGD:735594 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of LDLR mRNA CTD PMID:18593933 zinc atom increases response to substance EXP 6480464 LDLR gene mutant form results in increased susceptibility to Zinc deficiency CTD PMID:16140885 zinc atom multiple interactions EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Zinc deficiency] which results in increased expression of PPARG mRNA more ... CTD PMID:16140885 zinc(0) multiple interactions ISO RGD:735594 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of LDLR mRNA CTD PMID:18593933 zinc(0) increases response to substance EXP 6480464 LDLR gene mutant form results in increased susceptibility to Zinc deficiency CTD PMID:16140885 zinc(0) multiple interactions EXP 6480464 [LDLR gene mutant form results in increased susceptibility to Zinc deficiency] which results in increased expression of PPARG mRNA more ... CTD PMID:16140885 zoledronic acid increases expression ISO RGD:735594 6480464 zoledronic acid results in increased expression of LDLR mRNA CTD PMID:20977926
