Il1a (interleukin 1 alpha) - Rat Genome Database

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Gene: Il1a (interleukin 1 alpha) Mus musculus
Symbol: Il1a
Name: interleukin 1 alpha
RGD ID: 10789
Description: Enables cytokine activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production. Acts upstream of or within several processes, including connective tissue replacement involved in inflammatory response wound healing; ectopic germ cell programmed cell death; and extrinsic apoptotic signaling pathway in absence of ligand. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Il; IL-1 alpha; Il-1a; interleukin-1 alpha
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392129,141,530 - 129,151,892 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,141,530 - 129,151,892 (-)EnsemblGRCm39 Ensembl
GRCm382129,299,609 - 129,310,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,299,610 - 129,309,972 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,125,346 - 129,135,708 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,991,051 - 129,001,413 (-)NCBIMGSCv36mm8
Celera2130,527,298 - 130,537,642 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (IMP)
acute myeloid leukemia  (ISO)
allergic bronchopulmonary aspergillosis  (IEP)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
amnestic disorder  (ISO)
Anorexia  (ISO)
anthracosis  (ISO)
Arsenic Poisoning  (ISO)
aspiration pneumonia  (ISO)
asthma  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
beta thalassemia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Burns  (ISO)
cardiomyopathy  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemical Burns  (ISO)
cholestasis  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
chorioamnionitis  (ISO)
chronic progressive external ophthalmoplegia  (ISO)
common cold  (ISO)
corneal edema  (ISO)
Craniocerebral Trauma  (ISO)
Creutzfeldt-Jakob disease  (IEP)
cystic fibrosis  (ISO)
dermatomyositis  (ISO)
diabetic retinopathy  (ISO)
diarrhea  (ISO)
Disease Progression  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
Drug-induced Neutropenia  (ISO)
end stage renal disease  (ISO)
endometritis  (ISO)
Endotoxemia  (IEP,ISO)
Enterocolitis  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Leukemia  (IDA)
Experimental Melanoma  (IDA)
extrinsic allergic alveolitis  (IEP)
Fabry disease  (ISO)
Femoral Fractures  (ISO)
Fetal Growth Retardation  (ISO)
Fever  (ISO)
genetic disease  (ISO)
glomerulonephritis  (IEP)
graft-versus-host disease  (ISO)
Graves ophthalmopathy  (ISO)
head and neck squamous cell carcinoma  (ISO)
Heat Stroke  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhage  (ISO)
Hemorrhagic Shock  (ISO)
HIV Wasting Syndrome  (ISO)
Human Influenza  (IEP)
Hyperalgesia  (ISO)
hyperglycemia  (ISO)
Hypotension  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (IEP,ISO)
interstitial lung disease  (ISO)
Invasive Pulmonary Aspergillosis  (ISO)
iridocyclitis  (ISO)
juvenile rheumatoid arthritis  (ISO)
Kearns-Sayre syndrome  (ISO)
keratoconus  (ISO)
Knee Osteoarthritis  (IEP,ISO)
Leber hereditary optic neuropathy  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (IEP,ISO)
lung non-small cell carcinoma  (ISO)
malignant mesothelioma  (ISO)
MELAS syndrome  (ISO)
MERRF Syndrome  (ISO)
mesenchymal chondrosarcoma  (ISO)
Middle East respiratory syndrome  (HEP)
mitochondrial myopathy  (ISO)
multiple myeloma  (IMP,ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
non-alcoholic fatty liver disease  (ISO)
Oral Lichen Planus  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
otitis media  (ISO)
pancreatic cancer  (ISO)
Perennial Allergic Rhinitis  (ISO)
periodontitis  (ISO)
pneumonia  (ISO)
Poisoning  (IDA,ISO)
polymyositis  (ISO)
pulmonary fibrosis  (ISO)
pulmonary tuberculosis  (IEP)
Radiation Injuries  (ISO)
Radiation Pneumonitis  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (IMP)
Retina Reperfusion Injury  (ISO)
rheumatoid arthritis  (ISO)
Schnitzler syndrome  (ISO)
Sclerosis  (ISO)
severe acute respiratory syndrome  (HEP)
skin disease  (IMP,ISO)
Skin Neoplasms  (ISO)
tick infestation  (IEP)
type 1 diabetes mellitus  (IEP,ISO)
urinary tract infection  (IEP,ISO)
uveitis  (ISO)
varicocele  (ISO)
Venous Thrombosis  (ISO)
vitiligo  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(E)-cinnamyl alcohol  (ISO)
(R)-lipoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,3-benzothiazole-2-thiol  (EXP,ISO)
1,3-dinitrobenzene  (ISO)
1,4-dithiothreitol  (ISO)
1,4-phenylenediamine  (EXP)
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-nitropyrene  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2'-bipyridine  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (EXP,ISO)
2-methoxy-17beta-estradiol  (ISO)
2-tert-butylhydroquinone  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-acetyldeoxynivalenol  (EXP)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nitrobenzyl bromide  (ISO)
4-phenylbutyric acid  (EXP)
4-tert-butylphenol  (ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
8-Br-cAMP  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
acyclovir  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
albendazole  (ISO)
albuterol  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-hexylcinnamaldehyde  (EXP)
aluminium oxide  (ISO)
amikacin  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amodiaquine  (ISO)
amphibole asbestos  (ISO)
aniline  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthracene-1,8,9-triol  (EXP)
arachidonic acid  (EXP)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
azathioprine  (ISO)
benzalkonium chloride  (EXP,ISO)
benzatropine  (ISO)
benzbromarone  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (EXP)
benzocaine  (EXP)
benzoic acid  (ISO)
Benzoyl peroxide  (EXP,ISO)
benzyl alcohol  (ISO)
benzylpenicillin  (EXP)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
biperiden  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP,ISO)
bromfenac  (ISO)
bromoacetate  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium selenide  (ISO)
cadmium sulfate  (ISO)
Calcimycin  (EXP)
calcitriol  (EXP)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carazolol  (ISO)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carrageenan  (EXP)
ceric oxide  (ISO)
cetylpyridinium  (ISO)
CGP 52608  (ISO)
chlorobenzene  (EXP)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP,ISO)
chlorothalonil  (ISO)
chlorpromazine  (ISO)
choline  (EXP)
cinnamyl alcohol  (ISO)
ciprofloxacin  (ISO)
cisplatin  (EXP)
citral  (EXP)
clarithromycin  (ISO)
clavulanic acid  (ISO)
clobetasol  (EXP)
clofibrate  (EXP)
clomipramine  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
cortisol  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
daidzein  (EXP)
delta-tocotrienol  (EXP)
demeclocycline  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
Didecyldimethylammonium  (ISO)
diethyl maleate  (ISO)
diethylamine  (EXP)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
dodecane  (ISO)
doxorubicin  (EXP,ISO)
edaravone  (EXP)
enalapril  (ISO)
endosulfan  (ISO)
enilconazole  (EXP)
entacapone  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (ISO)
erythromycin A  (EXP)
esmolol  (ISO)
estriol  (ISO)
estrone 3-sulfate  (ISO)
ethambutol  (ISO)
ethanol  (EXP,ISO)
ethidium  (EXP)
ethionamide  (ISO)
ethylene glycol dimethacrylate  (EXP)
etodolac  (ISO)
eugenol  (ISO)
farnesol  (ISO)
ferroheme b  (EXP)
ferulic acid  (EXP)
Fexofenadine hydrochloride  (EXP,ISO)
flucloxacillin  (ISO)
fludrocortisone  (ISO)
flufenamic acid  (ISO)
fluocinolone acetonide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
fumonisin B1  (EXP)
furan  (EXP)
gadodiamide hydrate  (ISO)
gadolinium trichloride  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gemcitabine  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
geranial  (EXP)
geraniol  (ISO)
glyoxal  (ISO)
Goe 6976  (ISO)
gold atom  (EXP,ISO)
gold(0)  (EXP,ISO)
griseofulvin  (ISO)
heme b  (EXP)
hesperetin  (ISO)
hexadecane  (ISO)
hexadecanoic acid  (ISO)
Hexadimethrine bromide  (ISO)
hexane  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (EXP,ISO)
ibuprofen  (ISO)
imidurea  (EXP)
imiquimod  (EXP)
indometacin  (EXP,ISO)
ionomycin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
iron(III) citrate  (ISO)
isoeugenol  (EXP)
isoniazide  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
ketoconazole  (ISO)
kojic acid  (ISO)
L-1,4-dithiothreitol  (ISO)
lead nitrate  (EXP)
lenalidomide  (EXP)
leupeptin  (ISO)
levofloxacin  (ISO)
Licochalcone B  (ISO)
limonene  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
LY294002  (ISO)
m-xylene  (ISO)
manganese(II) chloride  (ISO)
mangiferin  (EXP)
mebendazole  (ISO)
melatonin  (EXP)
menadione  (ISO)
mephedrone  (ISO)
mercaptoethanol  (ISO)
mercury dichloride  (EXP)
mesalamine  (ISO)
metam  (EXP)
metaproterenol  (ISO)
methadone  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methoxyacetic acid  (ISO)
methyl methacrylate  (EXP)
methyl salicylate  (EXP)
methylisothiazolinone  (ISO)
metoprolol  (ISO)
mevalonic acid  (ISO)
mexiletine  (ISO)
Mezerein  (EXP)
mifepristone  (ISO)
mitomycin C  (ISO)
Mofezolac (TN)  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (ISO)
morphine  (EXP)
muramyl dipeptide  (EXP)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N,N-diethyl-m-toluamide  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-ethylmaleimide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naloxone  (EXP)
naproxen  (ISO)
nebivolol  (ISO)
nefazodone  (ISO)
neocuproine  (EXP)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitric oxide  (ISO)
nitrofen  (ISO)
nitrososulfamethoxazole  (ISO)
nonane  (ISO)
nonanoic acid  (EXP)
Nonidet P-40  (ISO)
Nonylphenol  (ISO)
nortriptyline  (ISO)
notoginsenoside R1  (EXP)
NS-398  (ISO)
ochratoxin A  (ISO)
octenidine  (ISO)
oleic acid  (ISO)
orciprenaline  (ISO)
Osajin  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paliperidone palmitate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
paricalcitol  (EXP)
parthenolide  (ISO)
pemetrexed  (ISO)
penbutolol  (ISO)
pentane-2,3-dione  (ISO)
peptidoglycan  (ISO)
perfluorododecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
phenol  (ISO)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphorus atom  (EXP)
phosphorus(.)  (EXP)
phthalic anhydride  (EXP)
pimecrolimus  (EXP)
pioglitazone  (ISO)
pirinixic acid  (EXP)
polycyclic arene  (ISO)
polymyxin B2  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
potassium hydroxide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
primaquine  (ISO)
primidone  (ISO)
probenecid  (EXP)
procyclidine  (ISO)
promethazine  (ISO)
propan-2-ol  (EXP)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
prostaglandin I2  (ISO)
pterostilbene  (EXP,ISO)
puerarin  (ISO)
Pyridostigmine bromide  (EXP,ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quinacrine  (EXP)
quinine  (ISO)
rac-lactic acid  (EXP,ISO)
ranitidine  (ISO)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
Riluzole  (ISO)
rofecoxib  (ISO)
Roridin A  (EXP)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
salicylic acid  (EXP)
SB 203580  (ISO)
SB-202190  (ISO)
SCH 23390  (ISO)
scopolamine  (EXP)
serpentine asbestos  (EXP,ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium perchlorate  (ISO)
streptozocin  (EXP)
sulindac  (ISO)
sumatriptan  (ISO)
T-2 toxin  (EXP,ISO)
telithromycin  (ISO)
terameprocol  (EXP)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
tetracyclines  (EXP)
tetradecane  (ISO)
Tetramethylthiourea  (ISO)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (EXP)
thioacetamide  (EXP,ISO)
thiostrepton  (ISO)
thiram  (ISO)
tienilic acid  (ISO)
titanium dioxide  (ISO)
Tolmetin glucuronide  (ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
topotecan  (ISO)
toremifene  (EXP)
trans-isoeugenol  (EXP)
trazodone  (ISO)
tremolite asbestos  (EXP)
tributylstannane  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (EXP)
tridecane  (ISO)
Trihexyphenidyl  (ISO)
trimethyltin  (EXP)
triptonide  (EXP)
Triton X-100  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
urethane  (ISO)
usnic acid  (ISO)
vadimezan  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (ISO)
verapamil  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
wortmannin  (ISO)
Y-27632  (ISO)
Z-Val-Phe-H  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc dichloride  (EXP)
zinc oxide  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)
zomepirac  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to heat  (ISO)
cellular response to lipopolysaccharide  (IBA)
connective tissue replacement involved in inflammatory response wound healing  (IMP)
cytokine-mediated signaling pathway  (IBA,ISO)
ectopic germ cell programmed cell death  (IGI)
extrinsic apoptotic signaling pathway in absence of ligand  (IMP)
fever generation  (IEA)
heart development  (ISO)
immune response  (IEA)
inflammatory response  (IBA,IDA)
interleukin-1-mediated signaling pathway  (IDA)
intracellular sodium ion homeostasis  (IDA)
keratinization  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of establishment of Sertoli cell barrier  (ISO)
positive regulation of angiogenesis  (IMP)
positive regulation of cell division  (IEA)
positive regulation of cytokine production  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (IBA,ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of immature T cell proliferation in thymus  (IBA)
positive regulation of interleukin-2 production  (IDA,ISO)
positive regulation of interleukin-6 production  (IDA,ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of mitotic nuclear division  (ISO)
positive regulation of monocyte chemotactic protein-1 production  (IDA)
positive regulation of neutrophil extravasation  (IDA)
positive regulation of neutrophil migration  (ISO)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of protein secretion  (ISO)
positive regulation of steroid biosynthetic process  (ISO)
positive regulation of stress-activated MAPK cascade  (ISO)
positive regulation of transcription by RNA polymerase II  (IGI)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of vascular endothelial growth factor production  (IMP)
regulation of actin cytoskeleton organization  (ISO)
regulation of nitric-oxide synthase activity  (IBA)
response to copper ion  (ISO)
response to gamma radiation  (ISO)
response to hypoxia  (ISO)
response to L-ascorbic acid  (ISO)
response to lipopolysaccharide  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to organonitrogen compound  (ISO)
response to ozone  (ISO)
spermatogenesis  (ISO)

Cellular Component

Molecular Function


References - curated
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PMID:17283139   PMID:17307724   PMID:17360358   PMID:17446350   PMID:17507369   PMID:17548042   PMID:17569781   PMID:17592750   PMID:17609389   PMID:17919942   PMID:17967442   PMID:17982084  
PMID:18086816   PMID:18195026   PMID:18204848   PMID:18234967   PMID:18311808   PMID:18434191   PMID:18490713   PMID:18516292   PMID:18596024   PMID:18615110   PMID:18691550   PMID:18778283  
PMID:18805969   PMID:18939951   PMID:19050234   PMID:19101514   PMID:19164472   PMID:19216058   PMID:19247983   PMID:19261731   PMID:19342666   PMID:19430902   PMID:19464323   PMID:19513570  
PMID:19561099   PMID:19571816   PMID:19576795   PMID:19625606   PMID:19666510   PMID:19703244   PMID:19720838   PMID:19766171   PMID:19839011   PMID:19853894   PMID:19926874   PMID:20108252  
PMID:20110570   PMID:20133797   PMID:20181656   PMID:20194588   PMID:20200351   PMID:20220089   PMID:20428172   PMID:20513002   PMID:20679512   PMID:20727790   PMID:20937871   PMID:20939024  
PMID:20956342   PMID:20974980   PMID:21093494   PMID:21107352   PMID:21148126   PMID:21191074   PMID:21219852   PMID:21653679   PMID:21677750   PMID:21722729   PMID:21777484   PMID:21828249  
PMID:21873635   PMID:21930960   PMID:21967771   PMID:22006336   PMID:22058415   PMID:22096246   PMID:22101928   PMID:22143786   PMID:22163019   PMID:22206014   PMID:22206506   PMID:22216303  
PMID:22236482   PMID:22291094   PMID:22328525   PMID:22387558   PMID:22444631   PMID:22483094   PMID:22682244   PMID:22802353   PMID:22914048   PMID:22972933   PMID:22992200   PMID:23029241  
PMID:23112187   PMID:23219391   PMID:23395675   PMID:23468973   PMID:23519030   PMID:23520553   PMID:23630357   PMID:23684408   PMID:23686480   PMID:23708968   PMID:23762309   PMID:23995233  
PMID:24194600   PMID:24336323   PMID:24395792   PMID:24395802   PMID:24416335   PMID:24431229   PMID:24434012   PMID:24458363   PMID:24582082   PMID:24644058   PMID:24651866   PMID:24790078  
PMID:24990750   PMID:25050810   PMID:25058342   PMID:25069982   PMID:25092334   PMID:25092891   PMID:25114230   PMID:25166912   PMID:25198773   PMID:25209981   PMID:25240383   PMID:25320279  
PMID:25323745   PMID:25367678   PMID:25371210   PMID:25405768   PMID:25421226   PMID:25497724   PMID:25505286   PMID:25693118   PMID:25748835   PMID:25748836   PMID:25862090   PMID:25864926  
PMID:25870999   PMID:25963822   PMID:26022690   PMID:26068648   PMID:26139463   PMID:26147228   PMID:26203636   PMID:26224856   PMID:26324502   PMID:26439902   PMID:26515418   PMID:26599867  
PMID:26682985   PMID:26941015   PMID:26978520   PMID:27139491   PMID:27211851   PMID:27226621   PMID:27318131   PMID:27339979   PMID:27349859   PMID:27365293   PMID:27434011   PMID:27476761  
PMID:27632536   PMID:27708283   PMID:27775548   PMID:27892465   PMID:27998728   PMID:28002730   PMID:28060905   PMID:28087239   PMID:28099414   PMID:28108299   PMID:28337831   PMID:28375155  
PMID:28410990   PMID:28504245   PMID:28630064   PMID:28706254   PMID:28939441   PMID:28947643   PMID:28953903   PMID:29120743   PMID:29180744   PMID:29281837   PMID:29382706   PMID:29391475  
PMID:29437957   PMID:29504104   PMID:29513560   PMID:29662944   PMID:29867931   PMID:30143634   PMID:30146158   PMID:30240702   PMID:30305325   PMID:30354247   PMID:30926232   PMID:30940725  
PMID:30988157   PMID:31019287   PMID:31030836   PMID:31110285   PMID:31169521   PMID:31325186   PMID:31332247   PMID:31393855   PMID:31420376   PMID:31505254   PMID:31562139   PMID:31566815  
PMID:31630209   PMID:31932497   PMID:31975434   PMID:32161110   PMID:32341377   PMID:32350081   PMID:32421904   PMID:32484881   PMID:32579912   PMID:32587089   PMID:32703941   PMID:32719333  
PMID:32841604   PMID:33051350   PMID:33087404   PMID:33130150   PMID:33147455   PMID:33361152   PMID:33620118   PMID:33722878   PMID:33761363   PMID:33798492   PMID:34439837   PMID:34525198  
PMID:34529751   PMID:34603325   PMID:34841579   PMID:34905516   PMID:35065198   PMID:35235356   PMID:35700169   PMID:36184639   PMID:36314682   PMID:36414671   PMID:36505497   PMID:36834943  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392129,141,530 - 129,151,892 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,141,530 - 129,151,892 (-)EnsemblGRCm39 Ensembl
GRCm382129,299,609 - 129,310,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,299,610 - 129,309,972 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,125,346 - 129,135,708 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,991,051 - 129,001,413 (-)NCBIMGSCv36mm8
Celera2130,527,298 - 130,537,642 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.9NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382112,773,925 - 112,784,493 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2112,773,925 - 112,784,493 (-)EnsemblGRCh38hg38GRCh38
GRCh372113,531,502 - 113,542,070 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,247,963 - 113,259,442 (-)NCBINCBI36Build 36hg18NCBI36
Build 342113,247,723 - 113,259,202NCBI
Celera2106,917,026 - 106,928,133 (-)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2105,986,068 - 105,997,547 (-)NCBIHuRef
CHM1_12113,535,646 - 113,546,806 (-)NCBICHM1_1
T2T-CHM13v2.02113,200,569 - 113,210,953 (-)NCBIT2T-CHM13v2.0
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.23116,526,601 - 116,537,055 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,526,604 - 116,536,822 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,424,348 - 120,434,552 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03129,019,955 - 129,030,165 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03126,680,432 - 126,690,642 (-)NCBIRnor_WKY
Rnor_6.03121,824,712 - 121,836,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,825,412 - 121,836,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,180,475 - 128,190,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,913,612 - 116,924,114 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,819,184 - 116,829,687 (-)NCBI
Celera3115,352,857 - 115,362,929 (-)NCBICelera
Cytogenetic Map3q36NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049554701,527,674 - 1,538,466 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,527,710 - 1,538,418 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan12A15,343,036 - 15,352,074 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,273,482 - 89,284,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,784,854 - 113,795,801 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,784,854 - 113,795,801 (-)Ensemblpanpan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.11736,969,581 - 36,979,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1736,970,573 - 36,979,435 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,739,697 - 36,748,565 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,745,380 - 37,755,259 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,746,372 - 37,755,235 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,881,972 - 36,890,833 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,938,236 - 36,947,096 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01737,152,126 - 37,160,990 (-)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440629282,315,498 - 82,324,623 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,210,809 - 1,218,315 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049367831,210,715 - 1,218,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl343,718,368 - 43,731,119 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1343,718,320 - 43,731,668 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,452,989 - 45,466,307 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3q12-q13NCBI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.11415,789,710 - 15,801,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,789,013 - 15,796,611 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660803,883,451 - 3,894,101 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_00462474912,795,946 - 12,805,154 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474912,795,967 - 12,805,658 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Il1a
412 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:410
Count of miRNA genes:310
Interacting mature miRNAs:352
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1558989Gnf4_mgrowth and fatness 4 (mouse)Not determined2128173704132714157Mouse

Markers in Region
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv372129,126,065 - 129,126,199UniSTSGRCm37
Celera2130,527,388 - 130,527,559UniSTS
Cytogenetic Map2FUniSTS
cM Map273.0UniSTS
Whitehead_YAC2 UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382129,300,159 - 129,300,314UniSTSGRCm38
MGSCv372129,125,895 - 129,126,050UniSTSGRCm37
Celera2130,527,847 - 130,528,002UniSTS
Cytogenetic Map2FUniSTS
cM Map273.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2FUniSTS
cM Map273.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2FUniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2FUniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382129,300,329 - 129,300,463UniSTSGRCm38
MGSCv372129,126,065 - 129,126,199UniSTSGRCm37
Celera2130,528,017 - 130,528,151UniSTS
Cytogenetic Map2FUniSTS



Reference Sequences
RefSeq Acc Id: ENSMUST00000028882   ⟹   ENSMUSP00000028882
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2129,141,530 - 129,151,892 (-)Ensembl
GRCm38.p6 Ensembl2129,299,610 - 129,309,972 (-)Ensembl
RefSeq Acc Id: NM_010554   ⟹   NP_034684
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm392129,141,530 - 129,151,892 (-)NCBI
GRCm382129,299,610 - 129,309,972 (-)NCBI
MGSCv372129,125,346 - 129,135,708 (-)RGD
Celera2130,527,298 - 130,537,642 (-)RGD
Reference Sequences
RefSeq Acc Id: NP_034684   ⟸   NM_010554
- UniProtKB: P01582 (UniProtKB/Swiss-Prot),   Q3U0Y6 (UniProtKB/TrEMBL),   A0A8C6HHN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000028882   ⟸   ENSMUST00000028882
Protein Domains
Interleukin-1 propeptide

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P01582-F1-model_v2 AlphaFold P01582 1-270 view protein structure

RGD ID:6831613
Promoter ID:MM_KWN:31691
SO ACC ID:SO:0000170
Tissues & Cell Lines:Liver
Mouse AssemblyChrPosition (strand)Source
MGSCv362129,135,576 - 129,136,076 (-)MPROMDB
RGD ID:6878710
Promoter ID:EPDNEW_M2806
Type:initiation region
Description:Mus musculus interleukin 1 alpha , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm382129,309,972 - 129,310,032EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96542 AgrOrtholog
Ensembl Genes ENSMUSG00000027399 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000028882 ENTREZGENE
  ENSMUSP00000028882.2 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028882 ENTREZGENE
  ENSMUST00000028882.2 UniProtKB/Swiss-Prot
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IL-1_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16175 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PANTHER PTHR10078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10078:SF33 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il1a PhenoGen
  INTRLEUKIN1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLEUKN1AB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Q62161_MOUSE UniProtKB/TrEMBL