Il1a (interleukin 1 alpha) - Rat Genome Database

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Gene: Il1a (interleukin 1 alpha) Mus musculus
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Symbol: Il1a
Name: interleukin 1 alpha
RGD ID: 10789
MGI Page MGI
Description: Enables cytokine activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production. Acts upstream of or within several processes, including connective tissue replacement involved in inflammatory response wound healing; ectopic germ cell programmed cell death; and extrinsic apoptotic signaling pathway in absence of ligand. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Il; IL-1 alpha; Il-1a; interleukin-1 alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,141,530 - 129,151,892 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,141,530 - 129,151,892 (-)EnsemblGRCm39 Ensembl
GRCm382129,299,609 - 129,310,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,299,610 - 129,309,972 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,125,346 - 129,135,708 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,991,051 - 129,001,413 (-)NCBIMGSCv36mm8
Celera2130,527,298 - 130,537,642 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (IMP)
acute myeloid leukemia  (ISO)
allergic bronchopulmonary aspergillosis  (IEP)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
amnestic disorder  (ISO)
Anorexia  (ISO)
anthracosis  (ISO)
Arsenic Poisoning  (ISO)
aspiration pneumonia  (ISO)
asthma  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
beta thalassemia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Burns  (ISO)
cardiomyopathy  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemical Burns  (ISO)
cholestasis  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
chorioamnionitis  (ISO)
chronic progressive external ophthalmoplegia  (ISO)
common cold  (ISO)
corneal edema  (ISO)
Craniocerebral Trauma  (ISO)
Creutzfeldt-Jakob disease  (IEP)
cystic fibrosis  (ISO)
dermatomyositis  (ISO)
diabetic retinopathy  (ISO)
diarrhea  (ISO)
Disease Progression  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
Drug-induced Neutropenia  (ISO)
end stage renal disease  (ISO)
endometritis  (ISO)
Endotoxemia  (IEP,ISO)
Enterocolitis  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Leukemia  (IDA)
Experimental Melanoma  (IDA)
extrinsic allergic alveolitis  (IEP)
Fabry disease  (ISO)
Femoral Fractures  (ISO)
Fetal Growth Retardation  (ISO)
Fever  (ISO)
glomerulonephritis  (IEP)
graft-versus-host disease  (ISO)
Graves ophthalmopathy  (ISO)
head and neck squamous cell carcinoma  (ISO)
Heat Stroke  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhage  (ISO)
Hemorrhagic Shock  (ISO)
HIV Wasting Syndrome  (ISO)
Human Influenza  (IEP)
Hyperalgesia  (ISO)
hyperglycemia  (ISO)
Hypotension  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (IEP,ISO)
interstitial lung disease  (ISO)
Invasive Pulmonary Aspergillosis  (ISO)
iridocyclitis  (ISO)
juvenile rheumatoid arthritis  (ISO)
Kearns-Sayre syndrome  (ISO)
keratoconus  (ISO)
Knee Osteoarthritis  (IEP,ISO)
Leber hereditary optic neuropathy  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (IEP,ISO)
lung non-small cell carcinoma  (ISO)
malignant mesothelioma  (ISO)
MELAS syndrome  (ISO)
MERRF Syndrome  (ISO)
mesenchymal chondrosarcoma  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Middle East respiratory syndrome  (HEP)
mitochondrial myopathy  (ISO)
multiple myeloma  (IMP,ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
Oral Lichen Planus  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
otitis media  (ISO)
pancreatic cancer  (ISO)
Perennial Allergic Rhinitis  (ISO)
periodontitis  (ISO)
pneumonia  (ISO)
Poisoning  (IDA,ISO)
polymyositis  (ISO)
pulmonary fibrosis  (ISO)
pulmonary tuberculosis  (IEP)
Radiation Injuries  (ISO)
Radiation Pneumonitis  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (IMP)
Retina Reperfusion Injury  (ISO)
rheumatoid arthritis  (ISO)
Schnitzler syndrome  (ISO)
Sclerosis  (ISO)
severe acute respiratory syndrome  (HEP)
skin disease  (IMP,ISO)
Skin Neoplasms  (ISO)
tick infestation  (IEP)
type 1 diabetes mellitus  (IEP,ISO)
urinary tract infection  (IEP,ISO)
uveitis  (ISO)
varicocele  (ISO)
Venous Thrombosis  (ISO)
vitiligo  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(E)-cinnamyl alcohol  (ISO)
(R)-lipoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (ISO)
(S)-duloxetine hydrochloride  (ISO)
(S)-nicotine  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,3-benzothiazole-2-thiol  (EXP,ISO)
1,3-dinitrobenzene  (ISO)
1,4-dithiothreitol  (ISO)
1,4-phenylenediamine  (EXP)
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-nitropyrene  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-bipyridine  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxyethyl methacrylate  (EXP)
2-hydroxypropanoic acid  (EXP,ISO)
2-methoxy-17beta-estradiol  (ISO)
2-palmitoylglycerol  (ISO)
2-tert-butylhydroquinone  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-acetyldeoxynivalenol  (EXP)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nitrobenzyl bromide  (ISO)
4-octylphenol  (ISO)
4-phenylbutyric acid  (EXP)
4-tert-butylphenol  (ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
8-Br-cAMP  (ISO)
AB-Fubinaca  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
acyclovir  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
albendazole  (ISO)
albuterol  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-hexylcinnamaldehyde  (EXP)
aluminium oxide  (ISO)
amikacin  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amodiaquine  (ISO)
amphibole asbestos  (ISO)
aniline  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthracene-1,8,9-triol  (EXP)
arachidonic acid  (EXP)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
ATP  (EXP)
azathioprine  (ISO)
BAPTA  (EXP)
benzalkonium chloride  (EXP,ISO)
benzatropine  (ISO)
benzbromarone  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (EXP)
benzocaine  (EXP)
benzoic acid  (ISO)
Benzoyl peroxide  (EXP,ISO)
benzyl alcohol  (ISO)
benzylpenicillin  (EXP)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
biperiden  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP,ISO)
bromfenac  (ISO)
bromoacetate  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
butylated hydroxyanisole  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium selenide  (ISO)
cadmium sulfate  (ISO)
Calcimycin  (EXP)
calcitriol  (EXP)
Calphostin C  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carazolol  (ISO)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carrageenan  (EXP)
carteolol  (ISO)
ceric oxide  (ISO)
cetylpyridinium  (ISO)
CGP 52608  (ISO)
chlorobenzene  (EXP)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP,ISO)
chlorothalonil  (ISO)
chlorpromazine  (ISO)
choline  (EXP)
cinnamyl alcohol  (ISO)
ciprofloxacin  (ISO)
cisplatin  (EXP)
citral  (EXP)
clarithromycin  (ISO)
clavulanic acid  (ISO)
clobetasol  (EXP)
clofibrate  (EXP)
clomipramine  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
cordycepin  (ISO)
corn oil  (ISO)
cortisol  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cytochalasin D  (EXP)
daidzein  (EXP)
delta-tocotrienol  (EXP)
demeclocycline  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
Didecyldimethylammonium  (ISO)
diethyl maleate  (ISO)
diethylamine  (EXP)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
dodecane  (ISO)
doxorubicin  (EXP,ISO)
edaravone  (EXP)
enalapril  (ISO)
endosulfan  (ISO)
enilconazole  (EXP)
entacapone  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (ISO)
erythromycin A  (EXP)
esmolol  (ISO)
estriol  (ISO)
estrone 3-sulfate  (ISO)
ethambutol  (ISO)
ethanol  (EXP,ISO)
ethidium  (EXP)
ethionamide  (ISO)
ethylene glycol dimethacrylate  (EXP)
etodolac  (ISO)
eugenol  (ISO)
farnesol  (ISO)
ferroheme b  (EXP)
ferulic acid  (EXP)
Fexofenadine hydrochloride  (EXP,ISO)
flucloxacillin  (ISO)
fludrocortisone  (ISO)
flufenamic acid  (ISO)
fluocinolone acetonide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
fumonisin B1  (EXP)
furan  (EXP)
gadodiamide hydrate  (ISO)
gadolinium trichloride  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gemcitabine  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
geranial  (EXP)
geraniol  (ISO)
glyoxal  (ISO)
Goe 6976  (ISO)
gold atom  (EXP,ISO)
gold(0)  (EXP,ISO)
griseofulvin  (ISO)
heme b  (EXP)
hesperetin  (ISO)
hexadecane  (ISO)
hexadecanoic acid  (ISO)
Hexadimethrine bromide  (ISO)
hexane  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (EXP,ISO)
ibuprofen  (ISO)
imidurea  (EXP)
imiquimod  (EXP)
indometacin  (EXP,ISO)
ionomycin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
iron(III) citrate  (ISO)
isoeugenol  (EXP)
isoniazide  (ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
ketoconazole  (ISO)
kojic acid  (ISO)
L-1,4-dithiothreitol  (ISO)
lead diacetate  (ISO)
lead nitrate  (EXP)
lenalidomide  (EXP)
leupeptin  (ISO)
levofloxacin  (ISO)
Licochalcone B  (ISO)
limonene  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
LY294002  (ISO)
m-xylene  (ISO)
malathion  (ISO)
manganese(II) chloride  (ISO)
mangiferin  (EXP)
mebendazole  (ISO)
melatonin  (EXP)
menadione  (ISO)
mephedrone  (ISO)
mercaptoethanol  (ISO)
mercury dichloride  (EXP)
mesalamine  (ISO)
metam  (EXP)
metaproterenol  (ISO)
methadone  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methoxyacetic acid  (ISO)
methyl methacrylate  (EXP)
methyl salicylate  (EXP)
methylisothiazolinone  (ISO)
metoprolol  (ISO)
mevalonic acid  (ISO)
mexiletine  (ISO)
Mezerein  (EXP)
microcystin-LR  (EXP)
mifepristone  (ISO)
mitomycin C  (ISO)
MJN110  (EXP)
Mofezolac (TN)  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (ISO)
morphine  (EXP)
muramyl dipeptide  (EXP)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N,N-diethyl-m-toluamide  (EXP,ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-ethylmaleimide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naloxone  (EXP)
naproxen  (ISO)
nebivolol  (ISO)
nefazodone  (ISO)
neocuproine  (EXP)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitric oxide  (ISO)
nitrofen  (ISO)
nitrososulfamethoxazole  (ISO)
nonane  (ISO)
nonanoic acid  (EXP)
Nonidet P-40  (ISO)
Nonylphenol  (ISO)
nortriptyline  (ISO)
notoginsenoside R1  (EXP)
NS-398  (ISO)
ochratoxin A  (ISO)
octenidine  (ISO)
oleic acid  (ISO)
orciprenaline  (ISO)
Osajin  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paliperidone palmitate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
paricalcitol  (EXP)
parthenolide  (ISO)
pemetrexed  (ISO)
penbutolol  (ISO)
pentane-2,3-dione  (ISO)
peptidoglycan  (ISO)
perfluorododecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
phenol  (ISO)
phloretin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphorus atom  (EXP)
phosphorus(.)  (EXP)
phthalic anhydride  (EXP)
pimecrolimus  (EXP)
pioglitazone  (ISO)
pirinixic acid  (EXP)
polycyclic arene  (ISO)
polymyxin B2  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
potassium hydroxide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
primaquine  (ISO)
primidone  (ISO)
probenecid  (EXP)
procyclidine  (ISO)
promethazine  (ISO)
propamocarb  (EXP)
propan-2-ol  (EXP)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
prostaglandin I2  (ISO)
pterostilbene  (EXP,ISO)
puerarin  (ISO)
Pyridostigmine bromide  (EXP,ISO)
quartz  (EXP)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quinacrine  (EXP)
quinine  (ISO)
rac-lactic acid  (EXP,ISO)
ranitidine  (ISO)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
Riluzole  (ISO)
rofecoxib  (ISO)
Roridin A  (EXP)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
salicylic acid  (EXP)
SB 203580  (ISO)
SB-202190  (ISO)
SCH 23390  (ISO)
scopolamine  (EXP)
serpentine asbestos  (EXP,ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sodium perchlorate  (ISO)
streptozocin  (EXP)
sulindac  (ISO)
sumatriptan  (ISO)
T-2 toxin  (EXP,ISO)
telithromycin  (ISO)
terameprocol  (EXP)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
tetracyclines  (EXP)
tetradecane  (ISO)
Tetramethylthiourea  (ISO)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (EXP)
thioacetamide  (EXP,ISO)
thiostrepton  (ISO)
thiram  (ISO)
tienilic acid  (ISO)
titanium dioxide  (ISO)
TMC-120A  (EXP)
Tolmetin glucuronide  (ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
topotecan  (ISO)
toremifene  (EXP)
trans-isoeugenol  (EXP)
trazodone  (ISO)
tremolite asbestos  (EXP)
tributylstannane  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (EXP)
tridecane  (ISO)
Trihexyphenidyl  (ISO)
trimethyltin  (EXP)
triptonide  (EXP)
Triton X-100  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
urethane  (ISO)
usnic acid  (ISO)
vadimezan  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (ISO)
verapamil  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
wortmannin  (ISO)
Y-27632  (ISO)
Z-Val-Phe-H  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc dichloride  (EXP)
zinc oxide  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)
zomepirac  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to heat  (ISO)
cellular response to lipopolysaccharide  (IBA)
connective tissue replacement involved in inflammatory response wound healing  (IMP)
cytokine-mediated signaling pathway  (IBA,ISO)
ectopic germ cell programmed cell death  (IGI)
extrinsic apoptotic signaling pathway in absence of ligand  (IMP)
fever generation  (IEA)
heart development  (ISO)
immune response  (IEA)
inflammatory response  (IBA)
intracellular sodium ion homeostasis  (IDA)
keratinization  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of establishment of Sertoli cell barrier  (ISO)
positive regulation of angiogenesis  (IMP)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of cell division  (IEA)
positive regulation of cytokine production  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (IBA,ISO)
positive regulation of immature T cell proliferation in thymus  (IBA)
positive regulation of interleukin-2 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of mitotic nuclear division  (ISO)
positive regulation of neutrophil migration  (ISO)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of protein secretion  (ISO)
positive regulation of steroid biosynthetic process  (ISO)
positive regulation of stress-activated MAPK cascade  (ISO)
positive regulation of transcription by RNA polymerase II  (IGI)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of vascular endothelial growth factor production  (IMP)
regulation of actin cytoskeleton organization  (ISO)
response to copper ion  (ISO)
response to gamma radiation  (ISO)
response to hypoxia  (ISO)
response to L-ascorbic acid  (ISO)
response to lipopolysaccharide  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to ozone  (ISO)
spermatogenesis  (ISO)

Cellular Component

Molecular Function

References

References - curated
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