Igf1r Mouse (-)-epigallocatechin 3-gallate multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Carbon Tetrachloride co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA CTD PMID:19646978 Igf1r Mouse (-)-epigallocatechin 3-gallate increases expression ISO IGF1R (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of IGF1R mRNA CTD PMID:22079256 Igf1r Mouse (-)-epigallocatechin 3-gallate multiple interactions ISO IGF1R (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA CTD PMID:22079256 Igf1r Mouse (-)-epigallocatechin 3-gallate decreases expression ISO IGF1R (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of IGF1R protein modified form CTD PMID:20346928 Igf1r Mouse (S)-naringenin multiple interactions ISO IGF1R (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of IGF1R mRNA and [naringenin metabolite co-treated with bisphenol A] results in increased expression of IGF1R mRNA CTD PMID:36235125 Igf1r Mouse (S)-nicotine decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Nicotine results in decreased expression of IGF1R mRNA and Nicotine results in decreased expression of IGF1R protein CTD PMID:20960268 and PMID:22265867 Igf1r Mouse (S)-nicotine affects expression ISO Igf1r (Rattus norvegicus) 6480464 Nicotine affects the expression of IGF1R mRNA CTD PMID:31972234 Igf1r Mouse (S)-nicotine increases expression ISO Igf1r (Rattus norvegicus) 6480464 Nicotine results in increased expression of IGF1R mRNA CTD PMID:20426880 Igf1r Mouse (Z)-ligustilide decreases phosphorylation ISO IGF1R (Homo sapiens) 6480464 ligustilide results in decreased phosphorylation of IGF1R protein CTD PMID:23973442 Igf1r Mouse 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:10965916 Igf1r Mouse 1,2-dimethylhydrazine decreases expression ISO Igf1r (Rattus norvegicus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of IGF1R mRNA CTD PMID:32387197 Igf1r Mouse 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of IGF1R mRNA] CTD PMID:22206623 Igf1r Mouse 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of IGF1R mRNA CTD PMID:22206623 Igf1r Mouse 17alpha-ethynylestradiol multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA more ... CTD PMID:23261820 Igf1r Mouse 17alpha-ethynylestradiol increases expression ISO Igf1r (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of IGF1R mRNA CTD PMID:23261820 Igf1r Mouse 17beta-estradiol multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Estradiol results in decreased expression of IGF1R mRNA] and Estradiol affects the reaction [CYP19A1 affects the expression of IGF1R mRNA] CTD PMID:11985600 and PMID:25210133 Igf1r Mouse 17beta-estradiol increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of IGF1R protein CTD PMID:16024245 and PMID:23094148 Igf1r Mouse 17beta-estradiol increases expression ISO IGF1R (Homo sapiens) 6480464 Estradiol results in increased expression of IGF1R mRNA CTD PMID:11813992 more ... Igf1r Mouse 17beta-estradiol multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of IGF1R mRNA more ... CTD PMID:22465879 and PMID:26496021 Igf1r Mouse 17beta-estradiol decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Estradiol results in decreased expression of IGF1R mRNA CTD PMID:20068009 more ... Igf1r Mouse 17beta-estradiol increases expression ISO Igf1r (Rattus norvegicus) 6480464 Estradiol results in increased expression of IGF1R mRNA CTD PMID:16522720 Igf1r Mouse 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IGF1R mRNA CTD PMID:17640349 Igf1r Mouse 17beta-estradiol multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Estradiol co-treated with bisphenol A] results in increased expression of IGF1R mRNA more ... CTD PMID:16024245 more ... Igf1r Mouse 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of IGF1R mRNA CTD PMID:14664709 and PMID:25210133 Igf1r Mouse 17beta-estradiol 17-glucosiduronic acid multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 4-(6-bromo-1 more ... CTD PMID:29090346 Igf1r Mouse 17beta-estradiol 17-glucosiduronic acid increases phosphorylation ISO Igf1r (Rattus norvegicus) 6480464 estradiol-17 beta-glucuronide results in increased phosphorylation of IGF1R protein CTD PMID:29090346 Igf1r Mouse 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO IGF1R (Homo sapiens) 6480464 Metribolone results in increased expression of IGF1R mRNA CTD PMID:18586690 and PMID:21440447 Igf1r Mouse 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO IGF1R (Homo sapiens) 6480464 Dapsone analog inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA] and resveratrol inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA] CTD PMID:18586690 and PMID:21440447 Igf1r Mouse 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO IGF1R (Homo sapiens) 6480464 Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R mRNA] and Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R protein] CTD PMID:18491370 Igf1r Mouse 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 nilutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of IGF1R protein] CTD PMID:10650946 Igf1r Mouse 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Dihydrotestosterone results in decreased expression of IGF1R protein CTD PMID:10650946 Igf1r Mouse 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO IGF1R (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of IGF1R mRNA and Dihydrotestosterone results in increased expression of IGF1R protein CTD PMID:18491370 and PMID:29581250 Igf1r Mouse 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO IGF1R (Homo sapiens) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 Igf1r Mouse 2,2',5,5'-tetrachlorobiphenyl affects expression ISO IGF1R (Homo sapiens) 6480464 2 more ... CTD PMID:21703328 Igf1r Mouse 2,3',4,4',5-Pentachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:31388691 Igf1r Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of IGF1R mRNA CTD PMID:16054899 Igf1r Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO IGF1R (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of IGF1R mRNA CTD PMID:23152189 Igf1r Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO IGF1R (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of IGF1R mRNA CTD PMID:17555868 and PMID:22903824 Igf1r Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IGF1R mRNA CTD PMID:15034205 Igf1r Mouse 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of IGF1R protein CTD PMID:9683191 Igf1r Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of IGF1R mRNA CTD PMID:16054899 Igf1r Mouse 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Igf1r (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 Igf1r Mouse 2,4-dinitrobenzenesulfonic acid decreases expression EXP 6480464 2 and 4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA CTD PMID:30116771 Igf1r Mouse 2-deoxy-D-glucose multiple interactions ISO IGF1R (Homo sapiens) 6480464 Deoxyglucose results in increased phosphorylation of and results in increased activity of IGF1R protein CTD PMID:23041229 Igf1r Mouse 2-hydroxypropanoic acid increases expression ISO IGF1R (Homo sapiens) 6480464 Lactic Acid results in increased expression of IGF1R mRNA CTD PMID:30851411 Igf1r Mouse 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO Igf1r (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 Igf1r Mouse 3,3',4,4',5-pentachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:37080397 Igf1r Mouse 3-chloropropane-1,2-diol decreases expression ISO IGF1R (Homo sapiens) 6480464 alpha-Chlorohydrin results in decreased expression of IGF1R mRNA CTD PMID:28070108 Igf1r Mouse 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of IGF1R mRNA CTD PMID:16054899 Igf1r Mouse 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of IGF1R mRNA CTD PMID:18648102 Igf1r Mouse 4,4'-sulfonyldiphenol increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 bisphenol S results in increased phosphorylation of IGF1R protein CTD PMID:37717640 Igf1r Mouse 4-hydroxy-17beta-estradiol increases expression ISO IGF1R (Homo sapiens) 6480464 4-hydroxyestradiol results in increased expression of IGF1R protein CTD PMID:23685341 Igf1r Mouse 4-hydroxynon-2-enal decreases expression ISO IGF1R (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in decreased expression of IGF1R mRNA CTD PMID:12419474 Igf1r Mouse 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of IGF1R mRNA CTD PMID:28973697 Igf1r Mouse 4-vinylcyclohexene dioxide affects expression EXP 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of IGF1R mRNA CTD PMID:20829426 Igf1r Mouse 5,6,7,8-tetrahydrofolic acid decreases expression ISO IGF1R (Homo sapiens) 6480464 5 more ... CTD PMID:16728583 Igf1r Mouse 5-fluorouracil multiple interactions ISO IGF1R (Homo sapiens) 6480464 Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein] and Fluorouracil results in decreased phosphorylation of and results in decreased activity of IGF1R protein CTD PMID:17918158 Igf1r Mouse 6-propyl-2-thiouracil decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of IGF1R mRNA CTD PMID:30047161 Igf1r Mouse 7,9-dihydro-1H-purine-2,6,8(3H)-trione affects abundance ISO IGF1R (Homo sapiens) 6480464 IGF1R gene SNP affects the abundance of Uric Acid CTD PMID:23263486 Igf1r Mouse acetamide increases expression ISO Igf1r (Rattus norvegicus) 6480464 acetamide results in increased expression of IGF1R mRNA CTD PMID:31881176 Igf1r Mouse acetazolamide increases expression EXP 6480464 Acetazolamide results in increased expression of IGF1R mRNA CTD PMID:19274763 Igf1r Mouse afimoxifene multiple interactions ISO IGF1R (Homo sapiens) 6480464 afimoxifene inhibits the reaction [Estrogens results in increased expression of IGF1R mRNA] CTD PMID:21233418 Igf1r Mouse afimoxifene multiple interactions EXP 6480464 afimoxifene results in increased phosphorylation of and results in increased activity of IGF1R protein and ESR1 protein promotes the reaction [afimoxifene results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:10965916 Igf1r Mouse afimoxifene decreases response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R results in decreased susceptibility to afimoxifene CTD PMID:21233418 Igf1r Mouse afimoxifene increases expression EXP 6480464 afimoxifene results in increased expression of IGF1R mRNA CTD PMID:17640349 Igf1r Mouse aflatoxin B1 increases expression ISO IGF1R (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of IGF1R mRNA and Aflatoxin B1 results in increased expression of IGF1R protein CTD PMID:20036727 Igf1r Mouse aflatoxin B1 increases methylation ISO IGF1R (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of IGF1R intron CTD PMID:30157460 Igf1r Mouse aflatoxin B1 decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Aflatoxin B1 results in decreased expression of IGF1R protein modified form CTD PMID:24373827 Igf1r Mouse aflatoxin B1 multiple interactions ISO IGF1R (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of and results in increased phosphorylation of IGF1R protein CTD PMID:20036727 Igf1r Mouse aldehydo-D-glucose increases expression ISO IGF1R (Homo sapiens) 6480464 Glucose results in increased expression of IGF1R mRNA and Glucose results in increased expression of IGF1R protein CTD PMID:38069837 and PMID:7826318 Igf1r Mouse aldehydo-D-glucose multiple interactions ISO IGF1R (Homo sapiens) 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 Igf1r Mouse aldehydo-D-glucose decreases expression ISO IGF1R (Homo sapiens) 6480464 Glucose results in decreased expression of IGF1R protein CTD PMID:23954465 Igf1r Mouse all-trans-retinoic acid multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R mRNA] and Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R protein] CTD PMID:21433279 Igf1r Mouse all-trans-retinoic acid increases expression ISO IGF1R (Homo sapiens) 6480464 Tretinoin results in increased expression of IGF1R protein CTD PMID:37853848 Igf1r Mouse all-trans-retinoic acid increases expression ISO Igf1r (Rattus norvegicus) 6480464 Tretinoin results in increased expression of IGF1R protein CTD PMID:21433279 Igf1r Mouse amino acid multiple interactions EXP 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in decreased expression of IGF1R mRNA] and H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in decreased expression of IGF1R mRNA]] CTD PMID:25309793 Igf1r Mouse amitrole decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Amitrole results in decreased expression of IGF1R mRNA CTD PMID:30047161 Igf1r Mouse ammonium chloride affects expression ISO Igf1r (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of IGF1R mRNA CTD PMID:16483693 Igf1r Mouse androgen antagonist multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 Igf1r Mouse AP20187 multiple interactions ISO IGF1R (Homo sapiens) 6480464 [AP20187 results in increased activity of IGF1R protein mutant form] which results in increased expression of EGR3 mRNA CTD PMID:29330302 Igf1r Mouse aristolochic acid A decreases expression ISO IGF1R (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of IGF1R mRNA CTD PMID:33212167 Igf1r Mouse Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of IGF1R mRNA CTD PMID:23650126 Igf1r Mouse arsane affects methylation ISO IGF1R (Homo sapiens) 6480464 Arsenic affects the methylation of IGF1R gene CTD PMID:25304211 Igf1r Mouse arsenic atom affects methylation ISO IGF1R (Homo sapiens) 6480464 Arsenic affects the methylation of IGF1R gene CTD PMID:25304211 Igf1r Mouse arsenous acid decreases expression ISO IGF1R (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:19769630 Igf1r Mouse arsenous acid increases expression ISO IGF1R (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of IGF1R mRNA CTD PMID:23911876 Igf1r Mouse arsenous acid affects response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R mRNA affects the susceptibility to Arsenic Trioxide CTD PMID:23911876 Igf1r Mouse arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:24831965 Igf1r Mouse azathioprine multiple interactions ISO IGF1R (Homo sapiens) 6480464 Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:23958494 Igf1r Mouse azathioprine decreases expression ISO IGF1R (Homo sapiens) 6480464 Azathioprine results in decreased expression of IGF1R protein CTD PMID:23958494 Igf1r Mouse benzo[a]pyrene increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 Benzo(a)pyrene results in increased phosphorylation of IGF1R protein CTD PMID:9683191 Igf1r Mouse benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of IGF1R intron CTD PMID:27901495 Igf1r Mouse benzo[a]pyrene decreases expression ISO IGF1R (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of IGF1R mRNA CTD PMID:20106945 more ... Igf1r Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of IGF1R mRNA CTD PMID:15034205 and PMID:21803694 Igf1r Mouse benzo[a]pyrene multiple interactions EXP 6480464 AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of IGF1R mRNA] CTD PMID:15034205 Igf1r Mouse benzo[a]pyrene diol epoxide I decreases expression ISO IGF1R (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 more ... Igf1r Mouse berberine multiple interactions ISO IGF1R (Homo sapiens) 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 Igf1r Mouse berberine increases expression ISO IGF1R (Homo sapiens) 6480464 Berberine results in increased expression of IGF1R protein CTD PMID:23954465 Igf1r Mouse beta-hexachlorocyclohexane increases expression EXP 6480464 beta-hexachlorocyclohexane results in increased expression of IGF1R mRNA CTD PMID:17640349 Igf1r Mouse bis(2-ethylhexyl) phthalate affects expression EXP 6480464 Diethylhexyl Phthalate affects the expression of IGF1R mRNA CTD PMID:37059381 Igf1r Mouse bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of IGF1R mRNA CTD PMID:29753845 Igf1r Mouse bisphenol A multiple interactions EXP 6480464 bisphenol A affects the reaction [CYP19A1 affects the expression of IGF1R mRNA] more ... CTD PMID:10965916 and PMID:11985600 Igf1r Mouse bisphenol A decreases expression ISO Igf1r (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of IGF1R mRNA CTD PMID:37570835 Igf1r Mouse bisphenol A affects expression ISO Igf1r (Rattus norvegicus) 6480464 bisphenol A affects the expression of IGF1R mRNA CTD PMID:25181051 Igf1r Mouse bisphenol A multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA more ... CTD PMID:25607892 more ... Igf1r Mouse bisphenol A increases expression ISO IGF1R (Homo sapiens) 6480464 bisphenol A analog results in increased expression of IGF1R mRNA and bisphenol A results in increased expression of IGF1R mRNA CTD PMID:23810794 more ... Igf1r Mouse bisphenol A multiple interactions ISO IGF1R (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of IGF1R gene more ... CTD PMID:23810794 more ... Igf1r Mouse bisphenol A increases methylation ISO IGF1R (Homo sapiens) 6480464 bisphenol A results in increased methylation of IGF1R gene and bisphenol A results in increased methylation of IGF1R promoter CTD PMID:22576693 and PMID:27271280 Igf1r Mouse bisphenol A decreases expression ISO IGF1R (Homo sapiens) 6480464 bisphenol A results in decreased expression of IGF1R mRNA CTD PMID:22576693 Igf1r Mouse bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of IGF1R protein CTD PMID:21988766 Igf1r Mouse Bisphenol B increases expression ISO IGF1R (Homo sapiens) 6480464 bisphenol B results in increased expression of IGF1R mRNA CTD PMID:32387340 Igf1r Mouse bisphenol F increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 bisphenol F results in increased phosphorylation of IGF1R protein CTD PMID:37717640 Igf1r Mouse BMS-754807 decreases phosphorylation ISO IGF1R (Homo sapiens) 6480464 BMS 754807 results in decreased phosphorylation of IGF1R protein CTD PMID:24986516 Igf1r Mouse BMS-754807 multiple interactions ISO IGF1R (Homo sapiens) 6480464 [BMS 754807 co-treated with palbociclib] results in decreased phosphorylation of IGF1R protein CTD PMID:24986516 Igf1r Mouse bortezomib increases response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R gene SNP results in increased susceptibility to Bortezomib CTD PMID:20864405 Igf1r Mouse butan-1-ol multiple interactions ISO IGF1R (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of IGF1R mRNA CTD PMID:29432896 Igf1r Mouse Butylparaben multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 Igf1r Mouse cadmium atom multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA more ... CTD PMID:35301059 and PMID:9648927 Igf1r Mouse cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IGF1R mRNA CTD PMID:29373603 and PMID:33259630 Igf1r Mouse cadmium atom increases expression ISO IGF1R (Homo sapiens) 6480464 Cadmium results in increased expression of IGF1R mRNA CTD PMID:24376830 Igf1r Mouse cadmium dichloride multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein] CTD PMID:21195169 Igf1r Mouse cadmium dichloride decreases expression ISO IGF1R (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of IGF1R mRNA CTD PMID:38568856 Igf1r Mouse cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IGF1R mRNA CTD PMID:29373603 and PMID:33259630 Igf1r Mouse cadmium dichloride multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1R mRNA more ... CTD PMID:23673518 and PMID:35301059 Igf1r Mouse cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of IGF1R mRNA CTD PMID:15501611 Igf1r Mouse cadmium dichloride increases phosphorylation ISO Igf1r (Rattus norvegicus) 6480464 Cadmium Chloride results in increased phosphorylation of IGF1R protein CTD PMID:21195169 Igf1r Mouse caffeine decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Caffeine results in decreased expression of IGF1R mRNA and Caffeine results in decreased expression of IGF1R protein CTD PMID:22583948 more ... Igf1r Mouse caffeine affects expression ISO Igf1r (Rattus norvegicus) 6480464 Caffeine affects the expression of IGF1R mRNA CTD PMID:29343424 Igf1r Mouse calcitriol affects expression ISO IGF1R (Homo sapiens) 6480464 Calcitriol affects the expression of IGF1R mRNA CTD PMID:19918113 Igf1r Mouse calcitriol increases expression ISO IGF1R (Homo sapiens) 6480464 Calcitriol results in increased expression of IGF1R mRNA CTD PMID:21592394 Igf1r Mouse calcitriol multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of IGF1R mRNA CTD PMID:21592394 Igf1r Mouse capsaicin increases expression ISO IGF1R (Homo sapiens) 6480464 Capsaicin results in increased expression of IGF1R mRNA CTD PMID:21310942 Igf1r Mouse capsaicin multiple interactions ISO IGF1R (Homo sapiens) 6480464 TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA] CTD PMID:21310942 Igf1r Mouse captan decreases expression EXP 6480464 Captan results in decreased expression of IGF1R mRNA CTD PMID:31558096 Igf1r Mouse carbamazepine affects expression ISO IGF1R (Homo sapiens) 6480464 Carbamazepine affects the expression of IGF1R mRNA CTD PMID:24752500 Igf1r Mouse carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 Igf1r Mouse Chimaphylin decreases expression ISO IGF1R (Homo sapiens) 6480464 chimaphilin results in decreased expression of IGF1R protein and chimaphilin results in decreased expression of IGF1R protein modified form CTD PMID:25980584 Igf1r Mouse chitin multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of IGF1R mRNA CTD PMID:30041514 Igf1r Mouse chloropicrin increases expression ISO IGF1R (Homo sapiens) 6480464 chloropicrin results in increased expression of IGF1R mRNA CTD PMID:26352163 Igf1r Mouse chromium(6+) increases expression ISO IGF1R (Homo sapiens) 6480464 chromium hexavalent ion results in increased expression of IGF1R protein CTD PMID:23748240 Igf1r Mouse chromium(6+) multiple interactions ISO IGF1R (Homo sapiens) 6480464 MIR143 inhibits the reaction [chromium hexavalent ion results in increased expression of IGF1R protein] CTD PMID:23748240 Igf1r Mouse chrysin multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 chrysin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] CTD PMID:29247772 Igf1r Mouse cisplatin decreases response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R protein results in decreased susceptibility to Cisplatin CTD PMID:21442237 Igf1r Mouse cisplatin decreases expression ISO IGF1R (Homo sapiens) 6480464 Cisplatin results in decreased expression of IGF1R mRNA CTD PMID:27594783 Igf1r Mouse clodronic acid increases expression ISO IGF1R (Homo sapiens) 6480464 Clodronic Acid results in increased expression of IGF1R mRNA CTD PMID:25596134 Igf1r Mouse cocaine affects expression ISO Igf1r (Rattus norvegicus) 6480464 Cocaine affects the expression of IGF1R mRNA CTD PMID:20187946 Igf1r Mouse copper atom multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of IGF1R protein and [Thiosemicarbazones binds to Copper] which results in decreased phosphorylation of IGF1R protein CTD PMID:20931265 Igf1r Mouse copper atom increases expression ISO Igf1r (Rattus norvegicus) 6480464 Copper deficiency results in increased expression of IGF1R protein CTD PMID:15734878 Igf1r Mouse copper(0) multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of IGF1R protein and [Thiosemicarbazones binds to Copper] which results in decreased phosphorylation of IGF1R protein CTD PMID:20931265 Igf1r Mouse copper(0) increases expression ISO Igf1r (Rattus norvegicus) 6480464 Copper deficiency results in increased expression of IGF1R protein CTD PMID:15734878 Igf1r Mouse corosolic acid multiple interactions EXP 6480464 corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 Igf1r Mouse corticosterone decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Corticosterone results in decreased expression of IGF1R mRNA and Corticosterone results in decreased expression of IGF1R protein CTD PMID:12807724 and PMID:29966748 Igf1r Mouse corticosterone multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [IGF2R protein co-treated with IGF1R protein] affects the reaction [IGF2 protein inhibits the reaction [Corticosterone results in decreased expression of SOD2 protein]] CTD PMID:24667322 Igf1r Mouse cortisol affects expression ISO IGF1R (Homo sapiens) 6480464 Hydrocortisone affects the expression of IGF1R mRNA CTD PMID:30528684 Igf1r Mouse cortisol multiple interactions ISO IGF1R (Homo sapiens) 6480464 Mifepristone affects the reaction [Hydrocortisone affects the expression of IGF1R mRNA] CTD PMID:30528684 Igf1r Mouse crocidolite asbestos decreases expression ISO IGF1R (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of IGF1R mRNA CTD PMID:23634900 Igf1r Mouse Cuprizon increases expression ISO Igf1r (Rattus norvegicus) 6480464 Cuprizone results in increased expression of IGF1R mRNA CTD PMID:26577399 Igf1r Mouse curcumin multiple interactions ISO IGF1R (Homo sapiens) 6480464 Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein] more ... CTD PMID:17499312 and PMID:17918158 Igf1r Mouse curcumin decreases expression ISO IGF1R (Homo sapiens) 6480464 Curcumin analog results in decreased expression of IGF1R mRNA and Curcumin results in decreased expression of IGF1R mRNA CTD PMID:17499312 and PMID:26409325 Igf1r Mouse cyclosporin A decreases expression ISO IGF1R (Homo sapiens) 6480464 Cyclosporine results in decreased expression of IGF1R mRNA CTD PMID:25562108 Igf1r Mouse cypermethrin increases expression ISO IGF1R (Homo sapiens) 6480464 cypermethrin results in increased expression of IGF1R mRNA CTD PMID:27704156 Igf1r Mouse D-glucose increases expression ISO IGF1R (Homo sapiens) 6480464 Glucose results in increased expression of IGF1R mRNA and Glucose results in increased expression of IGF1R protein CTD PMID:38069837 and PMID:7826318 Igf1r Mouse D-glucose decreases expression ISO IGF1R (Homo sapiens) 6480464 Glucose results in decreased expression of IGF1R protein CTD PMID:23954465 Igf1r Mouse D-glucose multiple interactions ISO IGF1R (Homo sapiens) 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 Igf1r Mouse daidzein decreases expression ISO IGF1R (Homo sapiens) 6480464 daidzein results in decreased expression of IGF1R mRNA CTD PMID:16865672 Igf1r Mouse dapsone multiple interactions ISO IGF1R (Homo sapiens) 6480464 Dapsone analog inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA] CTD PMID:21440447 Igf1r Mouse DDE multiple interactions ISO IGF1R (Homo sapiens) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 Igf1r Mouse deguelin decreases expression ISO IGF1R (Homo sapiens) 6480464 deguelin metabolite results in decreased expression of IGF1R protein more ... CTD PMID:19139008 and PMID:33512557 Igf1r Mouse dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of IGF1R mRNA CTD PMID:16054899 Igf1r Mouse dexamethasone decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Dexamethasone results in decreased expression of IGF1R mRNA and Dexamethasone results in decreased expression of IGF1R protein CTD PMID:19853640 and PMID:35148621 Igf1r Mouse dexamethasone decreases expression ISO IGF1R (Homo sapiens) 6480464 Dexamethasone results in decreased expression of IGF1R mRNA CTD PMID:25047013 Igf1r Mouse diarsenic trioxide affects response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R mRNA affects the susceptibility to Arsenic Trioxide CTD PMID:23911876 Igf1r Mouse diarsenic trioxide increases expression ISO IGF1R (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of IGF1R mRNA CTD PMID:23911876 Igf1r Mouse diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:24831965 Igf1r Mouse diarsenic trioxide decreases expression ISO IGF1R (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of IGF1R mRNA CTD PMID:19769630 Igf1r Mouse dibenz[a,h]anthracene decreases expression EXP 6480464 1 more ... CTD PMID:26377693 Igf1r Mouse Dibutyl phosphate affects expression ISO IGF1R (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of IGF1R mRNA CTD PMID:37042841 Igf1r Mouse dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of IGF1R mRNA CTD PMID:21266533 Igf1r Mouse dibutyl phthalate decreases phosphorylation EXP 6480464 Dibutyl Phthalate results in decreased phosphorylation of IGF1R protein CTD PMID:36993736 Igf1r Mouse dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of IGF1R mRNA CTD PMID:36993736 and PMID:37439711 Igf1r Mouse dibutyl phthalate multiple interactions EXP 6480464 Dibutyl Phthalate results in decreased expression of and results in decreased phosphorylation of IGF1R protein CTD PMID:37439711 Igf1r Mouse dibutyl phthalate increases expression ISO Igf1r (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of IGF1R mRNA and Dibutyl Phthalate results in increased expression of IGF1R protein CTD PMID:15829613 Igf1r Mouse diclofenac affects expression ISO IGF1R (Homo sapiens) 6480464 Diclofenac affects the expression of IGF1R mRNA CTD PMID:24752500 Igf1r Mouse dicrotophos increases expression ISO IGF1R (Homo sapiens) 6480464 dicrotophos results in increased expression of IGF1R mRNA CTD PMID:28302478 Igf1r Mouse diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of IGF1R mRNA CTD PMID:15171707 Igf1r Mouse diethylstilbestrol increases phosphorylation EXP 6480464 Diethylstilbestrol results in increased phosphorylation of IGF1R protein CTD PMID:15171707 Igf1r Mouse diethylstilbestrol multiple interactions EXP 6480464 Diethylstilbestrol results in increased phosphorylation of and results in increased activity of IGF1R protein and ESR1 protein promotes the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:10965916 Igf1r Mouse dihydrofolic acid decreases expression ISO IGF1R (Homo sapiens) 6480464 dihydrofolate results in decreased expression of IGF1R mRNA CTD PMID:16728583 Igf1r Mouse dimethylarsinic acid increases expression ISO Igf1r (Rattus norvegicus) 6480464 Cacodylic Acid results in increased expression of IGF1R mRNA CTD PMID:17481689 Igf1r Mouse dioxygen decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Oxygen deficiency results in decreased expression of IGF1R protein modified form CTD PMID:29139225 Igf1r Mouse dioxygen multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Tea inhibits the reaction [Oxygen deficiency results in decreased expression of IGF1R protein modified form] CTD PMID:29139225 Igf1r Mouse diquat increases response to substance EXP 6480464 IGF1R protein results in increased susceptibility to Diquat CTD PMID:22132081 Igf1r Mouse Doramectin decreases expression ISO Igf1r (Rattus norvegicus) 6480464 doramectin results in decreased expression of IGF1R mRNA CTD PMID:35137919 Igf1r Mouse dorsomorphin multiple interactions ISO IGF1R (Homo sapiens) 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Igf1r Mouse doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of IGF1R mRNA CTD PMID:25896364 Igf1r Mouse doxorubicin decreases expression ISO IGF1R (Homo sapiens) 6480464 Doxorubicin results in decreased expression of IGF1R mRNA CTD PMID:29803840 Igf1r Mouse doxorubicin decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Doxorubicin results in decreased expression of IGF1R mRNA CTD PMID:37597758 Igf1r Mouse doxorubicin multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of IGF1R mRNA] CTD PMID:37597758 Igf1r Mouse doxorubicin decreases response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R protein results in decreased susceptibility to Doxorubicin CTD PMID:25980584 Igf1r Mouse enzacamene multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 Igf1r Mouse enzalutamide decreases expression ISO IGF1R (Homo sapiens) 6480464 enzalutamide results in decreased expression of IGF1R mRNA CTD PMID:29581250 Igf1r Mouse equol decreases expression ISO IGF1R (Homo sapiens) 6480464 Equol results in decreased expression of IGF1R mRNA CTD PMID:16865672 Igf1r Mouse ethanol multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Ethanol] results in increased expression of IGF1R mRNA more ... CTD PMID:19735724 more ... Igf1r Mouse ethanol increases expression EXP 6480464 Ethanol results in increased expression of IGF1R mRNA CTD PMID:30319688 Igf1r Mouse ethanol affects expression EXP 6480464 Ethanol affects the expression of IGF1R mRNA CTD PMID:30319688 Igf1r Mouse ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of IGF1R mRNA CTD PMID:29524503 Igf1r Mouse ethanol decreases expression ISO IGF1R (Homo sapiens) 6480464 Ethanol results in decreased expression of IGF1R mRNA and Ethanol results in decreased expression of IGF1R protein modified form CTD PMID:29524503 and PMID:31226463 Igf1r Mouse ethanol affects expression ISO Igf1r (Rattus norvegicus) 6480464 Ethanol affects the expression of IGF1R mRNA and Ethanol affects the expression of IGF1R protein CTD PMID:31039417 and PMID:32535229 Igf1r Mouse ethanol decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Ethanol results in decreased expression of IGF1R mRNA and Ethanol results in decreased expression of IGF1R protein modified form CTD PMID:31226463 Igf1r Mouse ethanol increases activity ISO Igf1r (Rattus norvegicus) 6480464 Ethanol results in increased activity of IGF1R protein CTD PMID:19735724 Igf1r Mouse ethyl methanesulfonate increases expression ISO IGF1R (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of IGF1R mRNA CTD PMID:23649840 Igf1r Mouse etoposide affects response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R protein affects the susceptibility to Etoposide CTD PMID:15499378 Igf1r Mouse everolimus multiple interactions ISO IGF1R (Homo sapiens) 6480464 platycodin D inhibits the reaction [Everolimus results in increased expression of IGF1R protein] CTD PMID:28711525 Igf1r Mouse everolimus increases expression ISO IGF1R (Homo sapiens) 6480464 Everolimus results in increased expression of IGF1R mRNA and Everolimus results in increased expression of IGF1R protein CTD PMID:28711525 Igf1r Mouse fenpyroximate decreases expression ISO IGF1R (Homo sapiens) 6480464 fenpyroximate results in decreased expression of IGF1R mRNA CTD PMID:33512557 Igf1r Mouse fenvalerate increases expression ISO Igf1r (Rattus norvegicus) 6480464 fenvalerate results in increased expression of IGF1R mRNA CTD PMID:30307764 Igf1r Mouse folic acid multiple interactions ISO IGF1R (Homo sapiens) 6480464 Folic Acid inhibits the reaction [IGF1R protein results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:16728583 Igf1r Mouse folic acid multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 more ... CTD PMID:22206623 and PMID:29068127 Igf1r Mouse folic acid decreases expression ISO IGF1R (Homo sapiens) 6480464 Folic Acid results in decreased expression of IGF1R mRNA and Folic Acid results in decreased expression of IGF1R protein CTD PMID:16728583 Igf1r Mouse folpet decreases expression EXP 6480464 folpet results in decreased expression of IGF1R mRNA CTD PMID:31558096 Igf1r Mouse formaldehyde increases expression ISO IGF1R (Homo sapiens) 6480464 Formaldehyde results in increased expression of IGF1R mRNA CTD PMID:23649840 Igf1r Mouse FR900359 increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of IGF1R protein CTD PMID:37730182 Igf1r Mouse fructose increases expression ISO Igf1r (Rattus norvegicus) 6480464 Fructose results in increased expression of IGF1R protein CTD PMID:30480462 Igf1r Mouse fulvestrant multiple interactions ISO IGF1R (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of IGF1R gene more ... CTD PMID:19815064 more ... Igf1r Mouse fulvestrant multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 fulvestrant inhibits the reaction [[Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA] and fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of IGF1R mRNA] CTD PMID:23261820 Igf1r Mouse fulvestrant increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 fulvestrant results in increased phosphorylation of IGF1R protein CTD PMID:19815064 Igf1r Mouse gallic acid increases expression ISO IGF1R (Homo sapiens) 6480464 Gallic Acid results in increased expression of IGF1R mRNA CTD PMID:34408198 Igf1r Mouse gefitinib multiple interactions ISO IGF1R (Homo sapiens) 6480464 gefitinib promotes the reaction [IGF1R protein binds to EGFR protein] and tyrphostin AG 1024 inhibits the reaction [gefitinib results in increased phosphorylation of IGF1R protein] CTD PMID:17473213 Igf1r Mouse gefitinib increases phosphorylation ISO IGF1R (Homo sapiens) 6480464 gefitinib results in increased phosphorylation of IGF1R protein CTD PMID:17473213 Igf1r Mouse gemcitabine decreases expression ISO IGF1R (Homo sapiens) 6480464 Gemcitabine results in decreased expression of IGF1R mRNA CTD PMID:20103597 Igf1r Mouse genistein decreases expression ISO IGF1R (Homo sapiens) 6480464 Genistein results in decreased expression of IGF1R mRNA CTD PMID:16865672 Igf1r Mouse genistein increases expression EXP 6480464 Genistein results in increased expression of IGF1R mRNA CTD PMID:32186404 Igf1r Mouse genistein multiple interactions ISO IGF1R (Homo sapiens) 6480464 Genistein inhibits the reaction [bisphenol A results in increased expression of IGF1R mRNA] and Genistein inhibits the reaction [Estradiol results in increased expression of IGF1R mRNA] CTD PMID:23933164 Igf1r Mouse genistein increases expression ISO Igf1r (Rattus norvegicus) 6480464 Genistein results in increased expression of IGF1R mRNA and Genistein results in increased expression of IGF1R protein CTD PMID:16443925 and PMID:17049845 Igf1r Mouse genistein multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of IGF1R mRNA more ... CTD PMID:11896288 and PMID:16443925 Igf1r Mouse genistein multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Genistein results in increased phosphorylation of and results in increased activity of IGF1R protein] and Genistein results in increased phosphorylation of and results in increased activity of IGF1R protein CTD PMID:10965916 Igf1r Mouse gentamycin increases expression ISO Igf1r (Rattus norvegicus) 6480464 Gentamicins results in increased expression of IGF1R mRNA CTD PMID:22061828 Igf1r Mouse Ginkgoic acid decreases expression ISO IGF1R (Homo sapiens) 6480464 ginkgolic acid results in decreased expression of IGF1R protein CTD PMID:33508304 Igf1r Mouse Ginkgoic acid multiple interactions ISO IGF1R (Homo sapiens) 6480464 ginkgolic acid affects the localization of and results in decreased sumoylation of IGF1R protein CTD PMID:33508304 Igf1r Mouse glucose increases expression ISO IGF1R (Homo sapiens) 6480464 Glucose results in increased expression of IGF1R mRNA and Glucose results in increased expression of IGF1R protein CTD PMID:38069837 and PMID:7826318 Igf1r Mouse glucose multiple interactions ISO IGF1R (Homo sapiens) 6480464 Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein] CTD PMID:23954465 Igf1r Mouse glucose decreases expression ISO IGF1R (Homo sapiens) 6480464 Glucose results in decreased expression of IGF1R protein CTD PMID:23954465 Igf1r Mouse gold atom multiple interactions ISO IGF1R (Homo sapiens) 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] and Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 Igf1r Mouse gold(0) multiple interactions ISO IGF1R (Homo sapiens) 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] and Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 Igf1r Mouse herbicide decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Herbicides results in decreased expression of IGF1R mRNA CTD PMID:32360609 Igf1r Mouse hexachlorobenzene increases expression ISO Igf1r (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased expression of IGF1R protein CTD PMID:16237195 Igf1r Mouse hexachlorobenzene multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Hexachlorobenzene co-treated with Estradiol] results in increased expression of IGF1R protein more ... CTD PMID:19879930 and PMID:33571556 Igf1r Mouse hexachlorobenzene increases expression ISO IGF1R (Homo sapiens) 6480464 Hexachlorobenzene results in increased expression of IGF1R protein CTD PMID:19879930 Igf1r Mouse hexachlorobenzene multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Hexachlorobenzene inhibits the reaction [Methylnitrosourea results in increased expression of IGF1R protein] CTD PMID:16237195 Igf1r Mouse hydrogen peroxide decreases response to substance EXP 6480464 IGF1R gene mutant form results in decreased susceptibility to Hydrogen Peroxide CTD PMID:15761239 Igf1r Mouse Indeno[1,2,3-cd]pyrene increases expression ISO IGF1R (Homo sapiens) 6480464 indeno(1 more ... CTD PMID:32251684 Igf1r Mouse indometacin increases expression ISO Igf1r (Rattus norvegicus) 6480464 Indomethacin results in increased expression of IGF1R mRNA CTD PMID:18299717 Igf1r Mouse isoflurane decreases phosphorylation ISO Igf1r (Rattus norvegicus) 6480464 Isoflurane results in decreased phosphorylation of IGF1R protein CTD PMID:25597859 Igf1r Mouse isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of IGF1R mRNA CTD PMID:20003209 Igf1r Mouse L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of IGF1R protein CTD PMID:20530736 Igf1r Mouse lead diacetate multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [lead acetate results in increased abundance of Lead] which results in decreased expression of IGF1R mRNA and [lead acetate results in increased abundance of Lead] which results in decreased expression of IGF1R protein CTD PMID:36652739 Igf1r Mouse lead(0) multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [lead acetate results in increased abundance of Lead] which results in decreased expression of IGF1R mRNA and [lead acetate results in increased abundance of Lead] which results in decreased expression of IGF1R protein CTD PMID:36652739 Igf1r Mouse leuprolide multiple interactions ISO IGF1R (Homo sapiens) 6480464 Leuprolide results in decreased expression of and results in decreased phosphorylation of IGF1R protein CTD PMID:17143537 Igf1r Mouse linuron decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Linuron results in decreased expression of IGF1R mRNA CTD PMID:12730624 Igf1r Mouse lipopolysaccharide multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Honghua extract more ... CTD PMID:31486215 and PMID:31714667 Igf1r Mouse lovastatin multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Lovastatin promotes the reaction [INS protein results in increased phosphorylation of IGF1R protein] CTD PMID:19741129 Igf1r Mouse lycopene decreases expression ISO IGF1R (Homo sapiens) 6480464 lycopene results in decreased expression of IGF1R protein CTD PMID:17337101 Igf1r Mouse manganese(II) chloride increases expression ISO Igf1r (Rattus norvegicus) 6480464 manganese chloride results in increased expression of IGF1R protein CTD PMID:21402727 Igf1r Mouse manganese(II) chloride decreases expression ISO Igf1r (Rattus norvegicus) 6480464 manganese chloride results in decreased expression of IGF1R mRNA CTD PMID:19276553 Igf1r Mouse maslinic acid multiple interactions EXP 6480464 maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 Igf1r Mouse masoprocol multiple interactions ISO IGF1R (Homo sapiens) 6480464 Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R mRNA] more ... CTD PMID:18491370 and PMID:18645000 Igf1r Mouse masoprocol decreases activity ISO IGF1R (Homo sapiens) 6480464 Masoprocol results in decreased activity of IGF1R protein CTD PMID:18491370 Igf1r Mouse melatonin decreases expression ISO Igf1r (Rattus norvegicus) 156430315 melatonin decreases expression of Igf1r RNA in pulmonary artery smooth muscle cells RGD Igf1r Mouse menadione affects expression ISO IGF1R (Homo sapiens) 6480464 Vitamin K 3 affects the expression of IGF1R mRNA CTD PMID:20044591 Igf1r Mouse metformin multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Metformin co-treated with IGF1 protein] results in decreased expression of IGF1R mRNA more ... CTD PMID:21664031 Igf1r Mouse metformin multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] more ... CTD PMID:26492952 and PMID:36547818 Igf1r Mouse methcathinone increases expression ISO IGF1R (Homo sapiens) 6480464 monomethylpropion results in increased expression of IGF1R mRNA CTD PMID:22303338 Igf1r Mouse methimazole decreases expression ISO IGF1R (Homo sapiens) 6480464 Methimazole results in decreased expression of IGF1R mRNA CTD PMID:29990518 Igf1r Mouse methimazole decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Methimazole results in decreased expression of IGF1R mRNA CTD PMID:30047161 Igf1r Mouse methimazole increases expression EXP 6480464 Methimazole results in increased expression of IGF1R mRNA CTD PMID:29990518 Igf1r Mouse methoxychlor multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of IGF1R mRNA more ... CTD PMID:11896288 and PMID:16443925 Igf1r Mouse methoxychlor affects methylation ISO Igf1r (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of IGF1R gene CTD PMID:35440735 Igf1r Mouse methoxychlor increases methylation ISO Igf1r (Rattus norvegicus) 6480464 Methoxychlor results in increased methylation of IGF1R gene CTD PMID:23303685 Igf1r Mouse methoxychlor decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Methoxychlor results in decreased expression of IGF1R mRNA CTD PMID:23303685 Igf1r Mouse methoxychlor increases expression ISO Igf1r (Rattus norvegicus) 6480464 Methoxychlor results in increased expression of IGF1R mRNA and Methoxychlor results in increased expression of IGF1R protein CTD PMID:16443925 Igf1r Mouse methyl methanesulfonate increases expression ISO IGF1R (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of IGF1R mRNA CTD PMID:23649840 Igf1r Mouse methylarsonic acid increases expression ISO Igf1r (Rattus norvegicus) 6480464 monomethylarsonic acid results in increased expression of IGF1R mRNA CTD PMID:17481689 Igf1r Mouse methylmercury chloride affects expression ISO Igf1r (Rattus norvegicus) 6480464 methylmercuric chloride affects the expression of IGF1R mRNA CTD PMID:20864626 Igf1r Mouse methylmercury chloride multiple interactions ISO IGF1R (Homo sapiens) 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGF1R mRNA CTD PMID:27188386 Igf1r Mouse methylmercury chloride increases expression ISO IGF1R (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of IGF1R mRNA CTD PMID:23179753 and PMID:26272509 Igf1r Mouse mifepristone multiple interactions ISO IGF1R (Homo sapiens) 6480464 Mifepristone affects the reaction [Hydrocortisone affects the expression of IGF1R mRNA] CTD PMID:30528684 Igf1r Mouse mitoxantrone affects response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R protein affects the susceptibility to Mitoxantrone CTD PMID:15499378 Igf1r Mouse monocrotaline increases expression ISO Igf1r (Rattus norvegicus) 156430315 monocrotaline increases expression of Igf1r RNA in pulmonary artery smooth muscle cells RGD Igf1r Mouse monocrotaline multiple interactions ISO Igf1r (Rattus norvegicus) 156430315 melatonin inhibits the reaction [monocrotaline increases expression of Igf1r RNA in pulmonary artery smooth muscle cells] RGD Igf1r Mouse monosodium L-glutamate multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 GH1 protein inhibits the reaction [Sodium Glutamate results in increased expression of IGF1R mRNA] CTD PMID:7711889 Igf1r Mouse monosodium L-glutamate multiple interactions EXP 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of IGF1R mRNA and Sodium Glutamate affects the reaction [Azoxymethane affects the expression of IGF1R mRNA] CTD PMID:19001666 and PMID:22223845 Igf1r Mouse monosodium L-glutamate increases expression ISO Igf1r (Rattus norvegicus) 6480464 Sodium Glutamate results in increased expression of IGF1R mRNA CTD PMID:7711889 Igf1r Mouse Myrtucommulone A decreases expression EXP 6480464 myrtucommulone A results in decreased expression of IGF1R mRNA CTD PMID:26032814 Igf1r Mouse N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 N more ... CTD PMID:14644152 Igf1r Mouse N,N-diethyl-m-toluamide multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Permethrin co-treated with DEET] results in decreased methylation of IGF1R gene CTD PMID:33148267 Igf1r Mouse N-acetyl-L-cysteine multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein] CTD PMID:21195169 Igf1r Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO IGF1R (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein] CTD PMID:28711525 Igf1r Mouse N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of IGF1R gene CTD PMID:16461637 Igf1r Mouse N-ethyl-N-nitrosourea increases phosphorylation EXP 6480464 Ethylnitrosourea results in increased phosphorylation of IGF1R protein CTD PMID:32902906 Igf1r Mouse N-methyl-4-phenylpyridinium decreases expression ISO IGF1R (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of IGF1R protein CTD PMID:26364587 Igf1r Mouse N-methyl-4-phenylpyridinium multiple interactions ISO IGF1R (Homo sapiens) 6480464 INS protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of IGF1R protein] CTD PMID:26364587 Igf1r Mouse N-methyl-N-nitrosourea multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R mRNA more ... CTD PMID:16237195 and PMID:22465879 Igf1r Mouse N-methyl-N-nitrosourea increases expression ISO Igf1r (Rattus norvegicus) 6480464 Methylnitrosourea results in increased expression of IGF1R protein CTD PMID:16237195 Igf1r Mouse N-nitrosodiethylamine decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Diethylnitrosamine results in decreased expression of IGF1R mRNA CTD PMID:19542621 Igf1r Mouse N-nitrosodiethylamine multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of IGF1R mRNA CTD PMID:18977376 Igf1r Mouse N-nitrosomorpholine increases expression ISO Igf1r (Rattus norvegicus) 6480464 N-nitrosomorpholine results in increased expression of IGF1R protein CTD PMID:21411721 Igf1r Mouse N-phosphocreatine multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of IGF1R mRNA] CTD PMID:37597758 Igf1r Mouse nickel atom decreases expression ISO IGF1R (Homo sapiens) 6480464 Nickel results in decreased expression of IGF1R mRNA CTD PMID:25583101 Igf1r Mouse nickel subsulfide affects expression ISO Igf1r (Rattus norvegicus) 6480464 nickel subsulfide affects the expression of IGF1R mRNA CTD PMID:24952340 Igf1r Mouse niclosamide affects response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R protein affects the susceptibility to Niclosamide CTD PMID:27497986 Igf1r Mouse nicotine decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Nicotine results in decreased expression of IGF1R mRNA and Nicotine results in decreased expression of IGF1R protein CTD PMID:20960268 and PMID:22265867 Igf1r Mouse nicotine affects expression ISO Igf1r (Rattus norvegicus) 6480464 Nicotine affects the expression of IGF1R mRNA CTD PMID:31972234 Igf1r Mouse nicotine increases expression ISO Igf1r (Rattus norvegicus) 6480464 Nicotine results in increased expression of IGF1R mRNA CTD PMID:20426880 Igf1r Mouse nilutamide multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 nilutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of IGF1R protein] CTD PMID:10650946 Igf1r Mouse nitrofen multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R mRNA] and Tretinoin inhibits the reaction [nitrofen results in decreased expression of IGF1R protein] CTD PMID:21433279 Igf1r Mouse nitrofen decreases expression ISO Igf1r (Rattus norvegicus) 6480464 nitrofen results in decreased expression of IGF1R mRNA and nitrofen results in decreased expression of IGF1R protein CTD PMID:20620343 and PMID:21433279 Igf1r Mouse nitrogen mustard affects response to substance ISO IGF1R (Homo sapiens) 6480464 IGF1R protein affects the susceptibility to Nitrogen Mustard Compounds CTD PMID:15499378 Igf1r Mouse ochratoxin A increases expression ISO Igf1r (Rattus norvegicus) 6480464 ochratoxin A results in increased expression of IGF1R protein CTD PMID:17651772 Igf1r Mouse Octicizer affects binding ISO IGF1R (Homo sapiens) 6480464 2-ethylhexyldiphenylphosphate binds to IGF1R protein CTD PMID:35503735 Igf1r Mouse Octicizer decreases phosphorylation EXP 6480464 2-ethylhexyldiphenylphosphate results in decreased phosphorylation of IGF1R protein CTD PMID:35503735 Igf1r Mouse Octicizer decreases phosphorylation ISO IGF1R (Homo sapiens) 6480464 2-ethylhexyldiphenylphosphate results in decreased phosphorylation of IGF1R protein CTD PMID:35503735 Igf1r Mouse Octicizer multiple interactions ISO IGF1R (Homo sapiens) 6480464 2-ethylhexyldiphenylphosphate results in decreased activity of and results in decreased phosphorylation of IGF1R protein CTD PMID:35503735 Igf1r Mouse ozone increases expression ISO Igf1r (Rattus norvegicus) 6480464 Ozone results in increased expression of IGF1R mRNA CTD PMID:16330353 Igf1r Mouse p-menthan-3-ol decreases expression ISO IGF1R (Homo sapiens) 6480464 Menthol results in decreased expression of IGF1R mRNA CTD PMID:26760959 Igf1r Mouse palbociclib multiple interactions ISO IGF1R (Homo sapiens) 6480464 [BMS 754807 co-treated with palbociclib] results in decreased phosphorylation of IGF1R protein CTD PMID:24986516 Igf1r Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of IGF1R mRNA CTD PMID:17562736 Igf1r Mouse paracetamol increases expression ISO Igf1r (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of IGF1R mRNA CTD PMID:33387578 Igf1r Mouse paracetamol multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA CTD PMID:25607892 Igf1r Mouse paraquat affects response to substance EXP 6480464 IGF1R protein affects the susceptibility to Paraquat CTD PMID:23898955 Igf1r Mouse paraquat multiple interactions EXP 6480464 Paraquat results in increased expression of and results in increased phosphorylation of IGF1R protein CTD PMID:23898955 Igf1r Mouse perfluorododecanoic acid decreases expression ISO Igf1r (Rattus norvegicus) 6480464 perfluorododecanoic acid results in decreased expression of IGF1R mRNA CTD PMID:19397962 Igf1r Mouse perfluorooctane-1-sulfonic acid multiple interactions ISO IGF1R (Homo sapiens) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 Igf1r Mouse perfluorooctanoic acid multiple interactions ISO IGF1R (Homo sapiens) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2 more ... CTD PMID:33571556 Igf1r Mouse permethrin multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Permethrin co-treated with DEET] results in decreased methylation of IGF1R gene CTD PMID:33148267 Igf1r Mouse phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of IGF1R mRNA CTD PMID:23091169 Igf1r Mouse phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] and maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 Igf1r Mouse phorbol 13-acetate 12-myristate increases phosphorylation EXP 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein CTD PMID:26513295 Igf1r Mouse picolinic acid multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 picolinic acid promotes the reaction [INS1 protein results in increased expression of IGF1R mRNA] CTD PMID:20013160 Igf1r Mouse picoxystrobin decreases expression ISO IGF1R (Homo sapiens) 6480464 picoxystrobin results in decreased expression of IGF1R mRNA CTD PMID:33512557 Igf1r Mouse picropodophyllotoxin multiple interactions EXP 6480464 picropodophyllin binds to and results in decreased activity of IGF1R protein CTD PMID:21371294 Igf1r Mouse picropodophyllotoxin multiple interactions ISO IGF1R (Homo sapiens) 6480464 [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein] and [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] CTD PMID:23673518 Igf1r Mouse picropodophyllotoxin decreases activity ISO IGF1R (Homo sapiens) 6480464 picropodophyllin results in decreased activity of IGF1R protein CTD PMID:16166596 Igf1r Mouse piperine affects binding ISO IGF1R (Homo sapiens) 6480464 piperine binds to IGF1R protein CTD PMID:28341137 Igf1r Mouse platycodin D decreases expression ISO IGF1R (Homo sapiens) 6480464 platycodin D results in decreased expression of IGF1R protein CTD PMID:28711525 Igf1r Mouse platycodin D multiple interactions ISO IGF1R (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein] and platycodin D inhibits the reaction [Everolimus results in increased expression of IGF1R protein] CTD PMID:28711525 Igf1r Mouse potassium chromate multiple interactions ISO IGF1R (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA CTD PMID:22079256 Igf1r Mouse potassium chromate decreases expression ISO IGF1R (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of IGF1R mRNA CTD PMID:22079256 Igf1r Mouse progesterone decreases expression ISO IGF1R (Homo sapiens) 6480464 Progesterone results in decreased expression of IGF1R mRNA CTD PMID:18070364 Igf1r Mouse progesterone increases expression ISO Igf1r (Rattus norvegicus) 6480464 Progesterone results in increased expression of IGF1R mRNA CTD PMID:19853640 Igf1r Mouse progesterone multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R mRNA and [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R protein CTD PMID:22465879 Igf1r Mouse propiconazole decreases expression ISO Igf1r (Rattus norvegicus) 6480464 propiconazole results in decreased expression of IGF1R mRNA CTD PMID:30047161 Igf1r Mouse pyrimidifen decreases expression ISO IGF1R (Homo sapiens) 6480464 pyrimidifen results in decreased expression of IGF1R mRNA CTD PMID:33512557 Igf1r Mouse quercetin decreases expression ISO IGF1R (Homo sapiens) 6480464 Quercetin results in decreased expression of IGF1R mRNA and Quercetin results in decreased expression of IGF1R protein CTD PMID:12653748 more ... Igf1r Mouse quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:24353828 Igf1r Mouse quercetin multiple interactions ISO IGF1R (Homo sapiens) 6480464 Quercetin affects the reaction [[Fatty Acids co-treated with INS protein] affects the phosphorylation of IGF1R protein] CTD PMID:24648896 Igf1r Mouse quercitrin affects expression ISO IGF1R (Homo sapiens) 6480464 quercitrin affects the expression of IGF1R mRNA CTD PMID:25193878 Igf1r Mouse rac-lactic acid increases expression ISO IGF1R (Homo sapiens) 6480464 Lactic Acid results in increased expression of IGF1R mRNA CTD PMID:30851411 Igf1r Mouse resveratrol multiple interactions ISO IGF1R (Homo sapiens) 6480464 resveratrol inhibits the reaction [bisphenol A results in increased expression of IGF1R mRNA] more ... CTD PMID:18586690 more ... Igf1r Mouse resveratrol multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Resveratrol inhibits the reaction [bisphenol A results in decreased expression of IGF1R mRNA] CTD PMID:37570835 Igf1r Mouse resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [IGF1 protein binds to and results in increased phosphorylation of and results in increased activity of IGF1R protein] CTD PMID:24782617 Igf1r Mouse resveratrol increases expression EXP 6480464 resveratrol results in increased expression of IGF1R mRNA and resveratrol results in increased expression of IGF1R protein CTD PMID:17675339 more ... Igf1r Mouse resveratrol decreases phosphorylation ISO IGF1R (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of IGF1R protein CTD PMID:26394120 Igf1r Mouse resveratrol increases expression ISO Igf1r (Rattus norvegicus) 6480464 resveratrol results in increased expression of IGF1R mRNA CTD PMID:23848300 Igf1r Mouse resveratrol decreases expression ISO IGF1R (Homo sapiens) 6480464 resveratrol results in decreased expression of IGF1R mRNA and resveratrol results in decreased expression of IGF1R protein CTD PMID:18586690 more ... Igf1r Mouse RU 58668 affects expression ISO IGF1R (Homo sapiens) 6480464 RU 58668 affects the expression of IGF1R protein CTD PMID:15868441 Igf1r Mouse rutin multiple interactions ISO IGF1R (Homo sapiens) 6480464 Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein] CTD PMID:20015448 Igf1r Mouse SB 431542 multiple interactions ISO IGF1R (Homo sapiens) 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Igf1r Mouse Se-methyl-L-selenocysteine increases expression ISO IGF1R (Homo sapiens) 6480464 selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 Igf1r Mouse Se-methylselenocysteine increases expression ISO IGF1R (Homo sapiens) 6480464 selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 Igf1r Mouse simvastatin decreases expression ISO IGF1R (Homo sapiens) 6480464 Simvastatin results in decreased expression of IGF1R more ... CTD PMID:17158816 and PMID:18489904 Igf1r Mouse simvastatin multiple interactions EXP 6480464 [Simvastatin co-treated with NVP-AEW541] inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] and Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:27734117 Igf1r Mouse simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of IGF1R protein alternative form CTD PMID:17327694 Igf1r Mouse sirolimus affects activity ISO IGF1R (Homo sapiens) 6480464 Sirolimus affects the activity of IGF1R protein CTD PMID:16227402 Igf1r Mouse sirolimus multiple interactions ISO IGF1R (Homo sapiens) 6480464 Sirolimus promotes the reaction [IGF1R protein binds to and results in increased phosphorylation of IRS1 protein] CTD PMID:16227402 Igf1r Mouse sirtinol decreases expression ISO IGF1R (Homo sapiens) 6480464 sirtinol results in decreased expression of IGF1R mRNA CTD PMID:22495798 Igf1r Mouse sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of IGF1R mRNA CTD PMID:21795629 Igf1r Mouse sodium arsenite decreases expression ISO IGF1R (Homo sapiens) 6480464 sodium arsenite results in decreased expression of IGF1R mRNA CTD PMID:25879800 Igf1r Mouse sodium arsenite multiple interactions ISO IGF1R (Homo sapiens) 6480464 sodium arsenite inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:37853848 Igf1r Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of IGF1R mRNA CTD PMID:17077188 Igf1r Mouse sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of IGF1R mRNA CTD PMID:31558096 Igf1r Mouse sophoraflavanone B increases expression ISO Igf1r (Rattus norvegicus) 6480464 8-prenylnaringenin results in increased expression of IGF1R mRNA CTD PMID:16522720 Igf1r Mouse sorafenib decreases expression ISO IGF1R (Homo sapiens) 6480464 sorafenib results in decreased expression of IGF1R mRNA CTD PMID:26409325 Igf1r Mouse streptozocin decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Streptozocin results in decreased expression of IGF1R protein CTD PMID:23562514 Igf1r Mouse streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein CTD PMID:30721768 Igf1r Mouse streptozocin multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA more ... CTD PMID:23562514 and PMID:36547818 Igf1r Mouse succimer multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of IGF1R mRNA CTD PMID:26378955 Igf1r Mouse sucrose multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Sucrose] results in decreased expression of IGF1R protein and gamma-sitosterol inhibits the reaction [[Dietary Fats co-treated with Sucrose] results in decreased expression of IGF1R protein] CTD PMID:30461321 Igf1r Mouse sulfadimethoxine decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Sulfadimethoxine results in decreased expression of IGF1R mRNA CTD PMID:30047161 Igf1r Mouse sunitinib increases expression ISO IGF1R (Homo sapiens) 6480464 Sunitinib results in increased expression of IGF1R mRNA CTD PMID:31533062 Igf1r Mouse tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of IGF1R mRNA CTD PMID:21138602 Igf1r Mouse tanespimycin decreases expression ISO Igf1r (Rattus norvegicus) 6480464 tanespimycin results in decreased expression of IGF1R protein CTD PMID:22810956 Igf1r Mouse tanespimycin affects expression ISO IGF1R (Homo sapiens) 6480464 tanespimycin affects the expression of IGF1R protein CTD PMID:22810956 Igf1r Mouse tebufenpyrad decreases expression ISO IGF1R (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of IGF1R mRNA CTD PMID:33512557 Igf1r Mouse tert-butyl hydroperoxide decreases expression ISO IGF1R (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of IGF1R mRNA CTD PMID:12419474 Igf1r Mouse testosterone multiple interactions ISO IGF1R (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of IGF1R mRNA CTD PMID:21592394 Igf1r Mouse testosterone increases expression ISO Igf1r (Rattus norvegicus) 6480464 Testosterone results in increased expression of IGF1R mRNA CTD PMID:26492952 and PMID:29247772 Igf1r Mouse testosterone multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 chrysin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] and Metformin inhibits the reaction [Testosterone results in increased expression of IGF1R mRNA] CTD PMID:26492952 and PMID:29247772 Igf1r Mouse testosterone increases expression ISO IGF1R (Homo sapiens) 6480464 Testosterone results in increased expression of IGF1R mRNA CTD PMID:21592394 Igf1r Mouse testosterone increases expression EXP 6480464 Testosterone results in increased expression of IGF1R mRNA CTD PMID:21045173 Igf1r Mouse testosterone enanthate increases expression ISO Igf1r (Rattus norvegicus) 6480464 testosterone enanthate results in increased expression of IGF1R mRNA CTD PMID:23085480 Igf1r Mouse tetrachloromethane multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Carbon Tetrachloride co-treated with epigallocatechin gallate] results in decreased expression of IGF1R mRNA and IL10 protein affects the reaction [Carbon Tetrachloride results in increased expression of IGF1R protein] CTD PMID:12800242 and PMID:19646978 Igf1r Mouse tetrachloromethane increases expression ISO Igf1r (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of IGF1R mRNA and Carbon Tetrachloride results in increased expression of IGF1R protein CTD PMID:12800242 and PMID:27350269 Igf1r Mouse tetrachloromethane decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of IGF1R mRNA CTD PMID:17805973 Igf1r Mouse tetrathiomolybdate(2-) multiple interactions ISO IGF1R (Homo sapiens) 6480464 tetrathiomolybdate inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:18480265 Igf1r Mouse thyroxine increases expression ISO Igf1r (Rattus norvegicus) 6480464 Thyroxine results in increased expression of IGF1R protein CTD PMID:17447016 Igf1r Mouse thyroxine multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Vitamin E inhibits the reaction [Thyroxine results in increased expression of IGF1R protein] CTD PMID:17447016 Igf1r Mouse trichostatin A decreases expression ISO IGF1R (Homo sapiens) 6480464 trichostatin A results in decreased expression of IGF1R mRNA CTD PMID:28542535 Igf1r Mouse triclosan multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 [Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA and fulvestrant inhibits the reaction [[Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA] CTD PMID:23261820 Igf1r Mouse triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of IGF1R mRNA CTD PMID:29316351 Igf1r Mouse triphenyl phosphate affects expression ISO IGF1R (Homo sapiens) 6480464 triphenyl phosphate affects the expression of IGF1R mRNA CTD PMID:37042841 Igf1r Mouse tunicamycin decreases expression EXP 6480464 Tunicamycin results in decreased expression of IGF1R mRNA CTD PMID:17127020 Igf1r Mouse valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of IGF1R mRNA CTD PMID:17292431 Igf1r Mouse valproic acid affects splicing ISO Igf1r (Rattus norvegicus) 6480464 Valproic Acid affects the splicing of IGF1R mRNA CTD PMID:29427782 Igf1r Mouse valproic acid decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of IGF1R mRNA CTD PMID:29427782 Igf1r Mouse valproic acid multiple interactions ISO IGF1R (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGF1R mRNA CTD PMID:27188386 Igf1r Mouse valproic acid increases expression ISO IGF1R (Homo sapiens) 6480464 Valproic Acid results in increased expression of IGF1R mRNA CTD PMID:23179753 more ... Igf1r Mouse valproic acid increases methylation ISO IGF1R (Homo sapiens) 6480464 Valproic Acid results in increased methylation of IGF1R gene CTD PMID:29154799 Igf1r Mouse valproic acid affects expression ISO IGF1R (Homo sapiens) 6480464 Valproic Acid affects the expression of IGF1R mRNA CTD PMID:25979313 Igf1r Mouse vinclozolin decreases expression ISO Igf1r (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of IGF1R mRNA CTD PMID:23555832 Igf1r Mouse vinclozolin increases methylation ISO Igf1r (Rattus norvegicus) 6480464 vinclozolin results in increased methylation of IGF1R gene CTD PMID:31682807 Igf1r Mouse vitamin E multiple interactions ISO Igf1r (Rattus norvegicus) 6480464 Vitamin E inhibits the reaction [Thyroxine results in increased expression of IGF1R protein] CTD PMID:17447016 Igf1r Mouse vitamin E decreases expression ISO IGF1R (Homo sapiens) 6480464 Vitamin E results in decreased expression of IGF1R mRNA and Vitamin E results in decreased expression of IGF1R protein CTD PMID:19244175 and PMID:20015448 Igf1r Mouse vitamin E multiple interactions ISO IGF1R (Homo sapiens) 6480464 Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein] CTD PMID:20015448 Igf1r Mouse zinc atom affects expression ISO Igf1r (Rattus norvegicus) 6480464 Zinc affects the expression of IGF1R mRNA CTD PMID:16413754 Igf1r Mouse zinc atom multiple interactions ISO IGF1R (Homo sapiens) 6480464 Zinc promotes the reaction [IGF1 protein binds to IGF1R protein] and Zinc promotes the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 Igf1r Mouse zinc atom decreases expression ISO IGF1R (Homo sapiens) 6480464 Zinc results in decreased expression of IGF1R protein CTD PMID:19913001 Igf1r Mouse zinc atom increases phosphorylation ISO Igf1r (Rattus norvegicus) 6480464 Zinc results in increased phosphorylation of IGF1R protein CTD PMID:14644152 Igf1r Mouse zinc atom decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of IGF1R mRNA and Zinc deficiency results in decreased expression of IGF1R protein CTD PMID:21893222 Igf1r Mouse zinc sulfate multiple interactions ISO IGF1R (Homo sapiens) 6480464 IGF1R mutant form inhibits the reaction [Zinc Sulfate results in increased phosphorylation of AKT1 protein] more ... CTD PMID:19946718 Igf1r Mouse zinc(0) affects expression ISO Igf1r (Rattus norvegicus) 6480464 Zinc affects the expression of IGF1R mRNA CTD PMID:16413754 Igf1r Mouse zinc(0) decreases expression ISO Igf1r (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of IGF1R mRNA and Zinc deficiency results in decreased expression of IGF1R protein CTD PMID:21893222 Igf1r Mouse zinc(0) increases phosphorylation ISO Igf1r (Rattus norvegicus) 6480464 Zinc results in increased phosphorylation of IGF1R protein CTD PMID:14644152 Igf1r Mouse zinc(0) decreases expression ISO IGF1R (Homo sapiens) 6480464 Zinc results in decreased expression of IGF1R protein CTD PMID:19913001 Igf1r Mouse zinc(0) multiple interactions ISO IGF1R (Homo sapiens) 6480464 Zinc promotes the reaction [IGF1 protein binds to IGF1R protein] and Zinc promotes the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927