Ibsp (integrin binding sialoprotein) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ibsp (integrin binding sialoprotein) Mus musculus
Analyze
Symbol: Ibsp
Name: integrin binding sialoprotein
RGD ID: 10755
MGI Page MGI
Description: Predicted to enable integrin binding activity and small molecule binding activity. Acts upstream of or within bone mineralization; cellular response to growth factor stimulus; and extracellular matrix organization. Predicted to be located in extracellular space and vesicle. Is expressed in several structures, including facial prominence; jaw; limb; perichondrium; and skeleton. Orthologous to human IBSP (integrin binding sialoprotein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B; bone sialoprotein 2; bone sialoprotein II; Bs; BSP; BSP II; Bsp2; BSPII; cell-binding sialoprotein; integrin-binding sialoprotein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395104,447,153 - 104,459,338 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5104,447,037 - 104,459,335 (+)EnsemblGRCm39 Ensembl
GRCm385104,299,287 - 104,311,472 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5104,299,171 - 104,311,469 (+)EnsemblGRCm38mm10GRCm38
MGSCv375104,728,306 - 104,740,491 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365104,539,600 - 104,551,767 (+)NCBIMGSCv36mm8
Celera5101,608,398 - 101,620,486 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
17beta-estradiol  (EXP,ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
6-propyl-2-thiouracil  (EXP,ISO)
Actein  (EXP)
all-trans-retinoic acid  (EXP,ISO)
aluminium oxide  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
calcidiol  (ISO)
calciol  (EXP)
calcitriol  (ISO)
camptothecin  (ISO)
chlorpromazine  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
daidzein  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
diiodine  (EXP)
ethanol  (EXP,ISO)
eugenol  (ISO)
flavonoids  (ISO)
furan  (ISO)
genistein  (ISO)
geranylgeraniol  (ISO)
glycerol 2-phosphate  (EXP,ISO)
herbimycin  (ISO)
hydrogen peroxide  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (EXP,ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
lithium chloride  (EXP)
magnesium atom  (ISO)
methimazole  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nitroprusside  (ISO)
oxaliplatin  (ISO)
paraquat  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
simvastatin  (EXP)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP)
sodium chloride  (ISO)
spermine  (EXP)
tacrine  (ISO)
tamoxifen  (ISO)
telmisartan  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
extracellular space  (ISO,ISS)
vesicle  (ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acellular cementum morphology  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal bone remodeling  (IAGP)
abnormal cementum mineralization  (IAGP)
abnormal incisor morphology  (IAGP)
abnormal junctional epithelium morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal molar morphology  (IAGP)
abnormal molar root morphology  (IAGP)
abnormal osteoblast morphology  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal osteoid morphology  (IAGP)
abnormal periodontal ligament morphology  (IAGP)
abnormal periodontium morphology  (IAGP)
abnormal tooth root development  (IAGP)
abnormal tooth root resorption  (IAGP)
abnormal trabecular bone morphology  (IAGP)
alveolar process atrophy  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density of femur  (IAGP)
decreased bone trabecular spacing  (IAGP)
decreased femur compact bone thickness  (IAGP)
decreased osteoblast cell number  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased trabecular bone thickness  (IAGP)
delayed cranial suture closure  (IAGP)
delayed fontanelle closure  (IAGP)
delayed intramembranous bone ossification  (IAGP)
increased bone resorption  (IAGP)
increased bone trabecula number  (IAGP)
increased osteoclast cell number  (IAGP)
increased osteoid thickness  (IAGP)
increased trabecular bone volume  (IAGP)
large anterior fontanelle  (IAGP)
malocclusion  (IAGP)
misaligned incisors  (IAGP)
short femur  (IAGP)
wide coronal suture  (IAGP)
wide lambdoid suture  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease. Brito VGB, etal., Front Pharmacol. 2020 Nov 11;11:579926. doi: 10.3389/fphar.2020.579926. eCollection 2020.
2. Full-length sequence, localization, and chromosomal mapping of ameloblastin. A novel tooth-specific gene. Krebsbach PH, etal., J Biol Chem 1996 Feb 23;271(8):4431-5.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Nakashima K, etal., Cell 2002 Jan 11;108(1):17-29.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7848824   PMID:8180469   PMID:8835534   PMID:8894143   PMID:9545272   PMID:9933476   PMID:10213384   PMID:10349636   PMID:10467942   PMID:10742104   PMID:10751173   PMID:10906777  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:11722849   PMID:12033735   PMID:12379497   PMID:12414734   PMID:12469909   PMID:12477932   PMID:12737212   PMID:12963984   PMID:14512019  
PMID:14597577   PMID:15020240   PMID:15030764   PMID:15132997   PMID:15261838   PMID:15355562   PMID:15578713   PMID:15582152   PMID:15937924   PMID:16059638   PMID:16141072   PMID:16141073  
PMID:16326388   PMID:16368934   PMID:16419031   PMID:16518820   PMID:16602821   PMID:16751105   PMID:16829211   PMID:17141628   PMID:17199045   PMID:17204263   PMID:17336904   PMID:17374359  
PMID:17467682   PMID:17555517   PMID:17666434   PMID:17670790   PMID:17931618   PMID:17936262   PMID:18025304   PMID:18052755   PMID:18297083   PMID:18458111   PMID:18458345   PMID:18487609  
PMID:18547835   PMID:18624832   PMID:18669617   PMID:18757743   PMID:18927151   PMID:19047372   PMID:19144722   PMID:19320717   PMID:19419310   PMID:19458888   PMID:19489959   PMID:19518132  
PMID:19524706   PMID:19590010   PMID:19605502   PMID:19725955   PMID:19737917   PMID:19761880   PMID:19906844   PMID:20152828   PMID:20175913   PMID:20440000   PMID:20499347   PMID:20503377  
PMID:20570969   PMID:20589901   PMID:20812227   PMID:21148188   PMID:21267068   PMID:21308778   PMID:21367821   PMID:21677750   PMID:21741611   PMID:21873635   PMID:21911092   PMID:22155527  
PMID:22190639   PMID:22337375   PMID:22342532   PMID:22457635   PMID:22493482   PMID:22547067   PMID:22563320   PMID:22564414   PMID:22586700   PMID:22589746   PMID:22886599   PMID:22936354  
PMID:22936364   PMID:23026747   PMID:23183644   PMID:23322385   PMID:24417671   PMID:24497849   PMID:24583261   PMID:24816232   PMID:24927920   PMID:24930703   PMID:25160656   PMID:25209980  
PMID:25340332   PMID:25464126   PMID:25502698   PMID:25568170   PMID:25710686   PMID:25736226   PMID:25963390   PMID:26090674   PMID:26091038   PMID:26130257   PMID:26168040   PMID:26453795  
PMID:26681395   PMID:26739452   PMID:26763578   PMID:26794256   PMID:26826499   PMID:26927967   PMID:27052174   PMID:27704558   PMID:27804995   PMID:28437476   PMID:28866368   PMID:28983104  
PMID:29174564   PMID:29311969   PMID:29437042   PMID:29718910   PMID:30226623   PMID:30504126   PMID:31112308   PMID:31202927   PMID:32186512   PMID:32290615   PMID:32623954   PMID:32640236  
PMID:33253203   PMID:33308444   PMID:33482080   PMID:33824347   PMID:33840251   PMID:34465793   PMID:34880220   PMID:35075189   PMID:35140200   PMID:35167946   PMID:35512705   PMID:35686360  
PMID:35988140   PMID:36261010   PMID:36656123   PMID:36754021   PMID:37150306   PMID:37953328   PMID:39159790  


Genomics

Comparative Map Data
Ibsp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395104,447,153 - 104,459,338 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5104,447,037 - 104,459,335 (+)EnsemblGRCm39 Ensembl
GRCm385104,299,287 - 104,311,472 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5104,299,171 - 104,311,469 (+)EnsemblGRCm38mm10GRCm38
MGSCv375104,728,306 - 104,740,491 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365104,539,600 - 104,551,767 (+)NCBIMGSCv36mm8
Celera5101,608,398 - 101,620,486 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.68NCBI
IBSP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38487,799,554 - 87,812,435 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl487,799,554 - 87,812,435 (+)EnsemblGRCh38hg38GRCh38
GRCh37488,720,706 - 88,733,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36488,939,726 - 88,952,098 (+)NCBINCBI36Build 36hg18NCBI36
Build 34489,077,880 - 89,090,253NCBI
Celera486,008,963 - 86,021,864 (+)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef484,466,298 - 84,479,240 (+)NCBIHuRef
CHM1_1488,697,498 - 88,710,400 (+)NCBICHM1_1
T2T-CHM13v2.0491,125,985 - 91,138,857 (+)NCBIT2T-CHM13v2.0
Ibsp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,744,497 - 5,757,242 (-)NCBIGRCr8
mRatBN7.2145,439,825 - 5,452,570 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl145,439,829 - 5,452,693 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxPNT010000191.17,456 - 18,326 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,702,628 - 6,715,531 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0145,392,008 - 5,404,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0146,801,200 - 6,813,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl146,801,204 - 6,813,945 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0146,789,269 - 6,807,502 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,548,541 - 6,561,165 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1146,548,544 - 6,561,169 (-)NCBI
Celera145,578,651 - 5,591,441 (-)NCBICelera
RH 3.4 Map1489.7RGD
Cytogenetic Map14p22NCBI
Ibsp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554742,074,659 - 2,086,289 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554742,074,659 - 2,086,289 (-)NCBIChiLan1.0ChiLan1.0
IBSP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2385,806,206 - 85,819,449 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1486,068,641 - 86,081,881 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0480,061,960 - 80,105,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1490,817,072 - 90,830,021 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl490,817,072 - 90,830,021 (+)Ensemblpanpan1.1panPan2
IBSP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13211,187,188 - 11,200,860 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3211,187,160 - 11,200,846 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3230,753,404 - 30,767,085 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03211,240,790 - 11,254,453 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3211,240,716 - 11,254,466 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13211,323,638 - 11,337,299 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03211,149,296 - 11,162,980 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03228,790,260 - 28,803,929 (-)NCBIUU_Cfam_GSD_1.0
Ibsp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052851,896,163 - 1,905,843 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936905316,459 - 323,446 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936905316,459 - 323,446 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IBSP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8131,208,282 - 131,241,266 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18131,208,281 - 131,222,048 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28140,438,439 - 140,452,241 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IBSP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1736,170,411 - 36,185,099 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl736,174,903 - 36,184,278 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603714,894,526 - 14,905,166 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ibsp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248724,322,330 - 4,333,080 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248724,324,812 - 4,333,080 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:258
Count of miRNA genes:213
Interacting mature miRNAs:233
Transcripts:ENSMUST00000031246
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045978Tir10_mtrypanosome infection response 10 (mouse)Not determined598019649114021986Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
25314317Sccor3_msynaptonemal complex length to mean MLH1 count ratio 3 (mouse)5104347866114738061Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301877Bbaa3_mB.burgdorferi-associated arthritis 3 (mouse)Not determined599455285112465722Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
L23801  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,310,721 - 104,310,904UniSTSGRCm38
MGSCv375104,739,740 - 104,739,923UniSTSGRCm37
Celera592,506,790 - 92,506,973UniSTS
Cytogenetic Map5E5UniSTS
cM Map556.0UniSTS
Whitehead/MRC_RH51231.75UniSTS
Whitehead_YAC5 UniSTS
Ibsp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,310,541 - 104,310,806UniSTSGRCm38
MGSCv375104,739,560 - 104,739,825UniSTSGRCm37
Celera5101,619,694 - 101,619,962UniSTS
Cytogenetic Map5E5UniSTS
cM Map556.0UniSTS
L23801  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5E5UniSTS
Whitehead/MRC_RH51231.75UniSTS
Ibsp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5E5UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000031246   ⟹   ENSMUSP00000031246
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5104,447,037 - 104,459,335 (+)Ensembl
GRCm38.p6 Ensembl5104,299,171 - 104,311,469 (+)Ensembl
RefSeq Acc Id: NM_008318   ⟹   NP_032344
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395104,447,153 - 104,459,338 (+)NCBI
GRCm385104,299,287 - 104,311,472 (+)ENTREZGENE
MGSCv375104,728,306 - 104,740,491 (+)RGD
Celera592,506,222 - 92,507,102 (-)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032344   ⟸   NM_008318
- Peptide Label: precursor
- UniProtKB: Q61363 (UniProtKB/Swiss-Prot),   Q80VR6 (UniProtKB/Swiss-Prot),   Q61711 (UniProtKB/Swiss-Prot),   Q3TRM5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000031246   ⟸   ENSMUST00000031246

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61711-F1-model_v2 AlphaFold Q61711 1-324 view protein structure

Promoters
RGD ID:6887352
Promoter ID:EPDNEW_M7127
Type:multiple initiation site
Name:Ibsp_1
Description:Mus musculus integrin binding sialoprotein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385104,299,289 - 104,299,349EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96389 AgrOrtholog
Ensembl Genes ENSMUSG00000029306 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031246 ENTREZGENE
  ENSMUST00000031246.9 UniProtKB/Swiss-Prot
InterPro BSP_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15891 UniProtKB/Swiss-Prot
MGD MGI:96389 ENTREZGENE
NCBI Gene 15891 ENTREZGENE
PANTHER BONE SIALOPROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10345 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BSP_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ibsp PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
UniProt Q3TRM5 ENTREZGENE, UniProtKB/TrEMBL
  Q61363 ENTREZGENE
  Q61711 ENTREZGENE
  Q80VR6 ENTREZGENE
  SIAL_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q61363 UniProtKB/Swiss-Prot
  Q80VR6 UniProtKB/Swiss-Prot