Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Mus musculus
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Description: ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; NADP binding (ortholog); steroid binding (ortholog); INVOLVED IN lung development; glucocorticoid biosynthetic process (ortholog); glucocorticoid catabolic process (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH abnormal abdominal fat pad morphology; abnormal amniotic fluid composition; abnormal bone marrow cell physiology; ASSOCIATED WITH Obesity; Arthritis, Rheumatoid (ortholog); Cortisone Reductase Deficiency (ortholog); FOUND IN apical part of cell (ortholog); cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH (S)-nicotine; 11-dehydrocorticosterone; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11beta-HSD-1; 11beta-HSD1A; 11beta-hydroxysteroid dehydrogenase type 1; corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A); OTTMUSP00000039927; OTTMUSP00000039928; OTTMUSP00000039929; OTTMUSP00000039930
Homo sapiens (human) : HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1)  HGNC  AGR
Rattus norvegicus (Norway rat) : Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1)  AGR
Chinchilla lanigera (long-tailed chinchilla) : Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1)
Canis lupus familiaris (dog) : HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381193,221,640 - 193,264,049 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371195,047,834 - 195,090,239 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,922,413 - 194,964,769 (-)NCBImm8
Celera1200,096,784 - 200,141,189 (-)NCBICelera
Cytogenetic Map1 H6NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hsd11b1
AGR Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10734
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2017-12-05
Status: ACTIVE