Foxa2 (forkhead box A2) - Rat Genome Database

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Gene: Foxa2 (forkhead box A2) Mus musculus
Symbol: Foxa2
Name: forkhead box A2
RGD ID: 10719
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including glucose mediated signaling pathway; positive regulation of gastrulation; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including chordate embryonic development; lung development; and regulation of neuron differentiation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; endoderm; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: forkhead box protein A2; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3 beta; Hnf-3; HNF-3-beta; Hnf-3b; Hnf3; HNF3-be; HNF3-beta; Hnf3b; HNF3be; HNF3beta; Tcf-3b; Tcf3b
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392147,884,797 - 147,888,889 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2147,884,797 - 147,888,889 (-)EnsemblGRCm39 Ensembl
GRCm382148,042,877 - 148,046,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,042,877 - 148,046,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv372147,868,614 - 147,872,705 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362147,734,364 - 147,738,410 (-)NCBIMGSCv36mm8
Celera2149,306,403 - 149,310,523 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetaldehyde  (EXP)
acetic acid  (EXP)
aflatoxin B1  (ISO)
alachlor  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
arsenite(3-)  (ISO)
baicalin  (ISO)
Benoxacor  (EXP)
benzo[a]pyrene  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bromochloroacetic acid  (EXP)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (EXP,ISO)
carbendazim  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
curcumin  (EXP)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP)
cyproconazole  (EXP)
D-glucose  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dibenz[a,h]anthracene  (EXP)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
estriol  (ISO)
fentin chloride  (ISO)
flusilazole  (EXP)
folic acid  (EXP)
fumonisin B1  (EXP)
gamma-aminobutyric acid  (EXP)
genistein  (EXP)
geraniol  (ISO)
glafenine  (ISO)
glucose  (EXP)
hexaconazole  (EXP)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lead nitrate  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (EXP)
Mesaconitine  (ISO)
metformin  (EXP)
methimazole  (ISO)
methylmercury chloride  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodimethylamine  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nitrofen  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenformin  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
progesterone  (EXP)
Ptaquiloside  (EXP)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
testosterone  (ISO)
tetraphene  (EXP)
titanium dioxide  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vitamin D  (EXP)
vitamin E  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult locomotory behavior  (IMP)
anatomical structure formation involved in morphogenesis  (IGI)
anatomical structure morphogenesis  (IBA,IGI)
anterior/posterior pattern specification  (IGI)
cell development  (IMP)
cell differentiation  (IBA,TAS)
cell differentiation in hindbrain  (IGI,IMP)
cell fate specification  (IDA)
cellular response to cadmium ion  (IDA)
chromatin organization  (IEA)
connective tissue development  (IGI)
dopaminergic neuron differentiation  (IGI,IMP,ISO)
dorsal/ventral neural tube patterning  (IDA,IGI)
dorsal/ventral pattern formation  (IGI)
ectoderm formation  (IGI)
endocrine pancreas development  (IMP,ISO)
epithelial tube branching involved in lung morphogenesis  (IGI)
gene expression  (IMP)
glucose mediated signaling pathway  (IDA)
in utero embryonic development  (IMP)
lung development  (IGI)
lung epithelial cell differentiation  (IGI)
mesendoderm development  (IMP)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of neuron differentiation  (IGI)
negative regulation of transcription from RNA polymerase II promoter by glucose  (IDA)
neuron differentiation  (IGI,IMP)
neuron fate specification  (IGI,IMP)
Notch signaling pathway  (IDA)
pattern specification process  (IGI)
positive regulation of DNA-templated transcription  (IMP,ISO)
positive regulation of dopaminergic neuron differentiation  (IGI,IMP)
positive regulation of embryonic development  (IMP)
positive regulation of gastrulation  (IMP)
positive regulation of neuron differentiation  (IGI)
positive regulation of smoothened signaling pathway  (IGI)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,IMP,ISO)
positive regulation of transcription by RNA polymerase III  (IMP)
positive regulation of transcription from RNA polymerase II promoter by glucose  (IDA)
primitive streak formation  (IMP)
regulation of blood coagulation  (ISO)
regulation of DNA-templated transcription  (IDA,ISO)
regulation of gene expression  (IGI)
regulation of insulin secretion involved in cellular response to glucose stimulus  (IDA)
regulation of lipid metabolic process  (IDA,IMP)
regulation of steroid metabolic process  (IDA,IMP)
regulation of transcription by RNA polymerase II  (IBA,ISO)
response to insulin  (ISO)
response to interleukin-6  (TAS)
signal transduction involved in regulation of gene expression  (IDA)
smoothened signaling pathway  (IGI)
somite rostral/caudal axis specification  (IMP)
transcription by RNA polymerase II  (IDA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior cardinal vein morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cell death  (IAGP)
abnormal chordamesoderm morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal decidualization  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal direction of embryo turning  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryo invasion  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal endoderm development  (IAGP)
abnormal endometrial gland development  (IAGP)
abnormal eye development  (IAGP)
abnormal first pharyngeal arch artery morphology  (IAGP)
abnormal first pharyngeal arch morphology  (IAGP)
abnormal forebrain development  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal gait  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal heart development  (IAGP)
abnormal heart looping  (IAGP)
abnormal insulin secretion  (IAGP)
abnormal lung saccule morphology  (IAGP)
abnormal mesendoderm development  (IAGP)
abnormal metabolism  (IAGP)
abnormal nervous system development  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal notochord morphology  (IAGP)
abnormal optic vesicle formation  (IAGP)
abnormal pancreas development  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal pancreatic beta cell differentiation  (IAGP)
abnormal pancreatic beta cell morphology  (IAGP)
abnormal paraxial mesoderm morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal pharynx morphology  (IAGP)
abnormal primitive endoderm morphology  (IAGP)
abnormal primitive streak elongation  (IAGP)
abnormal primitive streak formation  (IAGP)
abnormal pulmonary alveolus epithelial cell morphology  (IAGP)
abnormal pulmonary alveolus wall morphology  (IAGP)
abnormal respiratory mechanics  (IAGP)
abnormal respiratory mucosa goblet cell morphology  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal second pharyngeal arch morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal somite shape  (IAGP)
abnormal surfactant composition  (IAGP)
abnormal surfactant secretion  (IAGP)
abnormal type II pneumocyte morphology  (IAGP)
abnormal uterus physiology  (IAGP)
abnormal vascular development  (IAGP)
absent alveolar lamellar bodies  (IAGP)
absent dorsal mesocardium  (IAGP)
absent estrous cycle  (IAGP)
absent estrus  (IAGP)
absent floor plate  (IAGP)
absent mesoderm  (IAGP)
absent notochord  (IAGP)
absent optic vesicle  (IAGP)
absent pancreatic duct  (IAGP)
absent primitive node  (IAGP)
absent type I pneumocytes  (IAGP)
atelectasis  (IAGP)
atrial septal defect  (IAGP)
circling  (IAGP)
cyanosis  (IAGP)
decreased body size  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glucagon level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased embryo size  (IAGP)
decreased embryonic neuroepithelium thickness  (IAGP)
decreased endometrial gland number  (IAGP)
decreased forebrain size  (IAGP)
decreased hindbrain size  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased litter size  (IAGP)
decreased lung compliance  (IAGP)
decreased pancreatic alpha cell number  (IAGP)
decreased pancreatic beta cell number  (IAGP)
decreased skin turgor  (IAGP)
decreased somite size  (IAGP)
decreased spinal cord size  (IAGP)
decreased surfactant secretion  (IAGP)
decreased total body fat amount  (IAGP)
delayed embryo turning  (IAGP)
delayed heart development  (IAGP)
dilated respiratory conducting tube  (IAGP)
disorganized pancreatic islets  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
embryonic-extraembryonic boundary constriction  (IAGP)
exocrine pancreas hypoplasia  (IAGP)
fused somites  (IAGP)
hunched posture  (IAGP)
hyperactivity  (IAGP)
hyperglycemia  (IAGP)
hypoglycemia  (IAGP)
impaired embryo implantation  (IAGP)
impaired lung alveolus development  (IAGP)
impaired righting response  (IAGP)
improved glucose tolerance  (IAGP)
increased airway resistance  (IAGP)
increased basal metabolism  (IAGP)
increased carbon dioxide production  (IAGP)
increased circulating free fatty acids level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased glycogen level  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased insulin sensitivity  (IAGP)
increased lean body mass  (IAGP)
increased liver triglyceride level  (IAGP)
increased macrophage cell number  (IAGP)
increased miscarriage rate  (IAGP)
increased neutrophil cell number  (IAGP)
increased oxygen consumption  (IAGP)
increased respiratory mucosa goblet cell number  (IAGP)
increased susceptibility to injury  (IAGP)
kinked neural tube  (IAGP)
long incisors  (IAGP)
malocclusion  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
pancreas hypoplasia  (IAGP)
pancreatic islet hypoplasia  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
pulmonary hyaline membrane formation  (IAGP)
pulmonary vascular congestion  (IAGP)
pup cannibalization  (IAGP)
reduced female fertility  (IAGP)
respiratory distress  (IAGP)
respiratory system inflammation  (IAGP)
rostral body truncation  (IAGP)
seizures  (IAGP)
situs ambiguus  (IAGP)
small first pharyngeal arch  (IAGP)
small pharynx  (IAGP)
small second pharyngeal arch  (IAGP)

References - curated
# Reference Title Reference Citation
1. Genetic variation in the hepatocyte nuclear factor-3beta gene (HNF3B) does not contribute to maturity-onset diabetes of the young in French Caucasians. Abderrahmani A, etal., Diabetes. 2000 Feb;49(2):306-8.
2. SLC2A2 gene expression in kidney of diabetic rats is regulated by HNF-1alpha and HNF-3beta. Freitas HS, etal., Mol Cell Endocrinol. 2009 Jun 16;305(1-2):63-70. Epub 2009 Mar 4.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia. Sund NJ, etal., Genes Dev. 2001 Jul 1;15(13):1706-15.
11. Genetic variants of FOXA2: risk of type 2 diabetes and effect on metabolic traits in North Indians. Tabassum R, etal., J Hum Genet. 2008;53(11-12):957-65. Epub 2008 Sep 17.
12. The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH. Wang R, etal., Sci Rep. 2015 Dec 11;5:17826. doi: 10.1038/srep17826.
13. Role of Foxa-2 in adipocyte metabolism and differentiation. Wolfrum C, etal., J Clin Invest. 2003 Aug;112(3):345-56. Epub 2003 Jul 15.
14. Identification of missense mutations in the hepatocyte nuclear factor-3beta gene in Japanese subjects with late-onset Type II diabetes mellitus. Zhu Q, etal., Diabetologia. 2000 Sep;43(9):1197-200.
Additional References at PubMed
PMID:1363228   PMID:1612587   PMID:1672118   PMID:7606937   PMID:7618107   PMID:7657163   PMID:7671817   PMID:7689224   PMID:7700351   PMID:7720556   PMID:7768172   PMID:7776982  
PMID:7916661   PMID:7925656   PMID:7958446   PMID:7958910   PMID:8001822   PMID:8034310   PMID:8069909   PMID:8069910   PMID:8187630   PMID:8248124   PMID:8287471   PMID:8306889  
PMID:8375339   PMID:8530406   PMID:8543149   PMID:8565076   PMID:8565836   PMID:8610012   PMID:8625829   PMID:8674409   PMID:8756299   PMID:8787761   PMID:8813084   PMID:8837770  
PMID:8951074   PMID:8978605   PMID:9032290   PMID:9078367   PMID:9078438   PMID:9118802   PMID:9119385   PMID:9136932   PMID:9136933   PMID:9152011   PMID:9216996   PMID:9226455  
PMID:9232602   PMID:9247260   PMID:9260895   PMID:9262482   PMID:9315659   PMID:9334279   PMID:9371744   PMID:9415428   PMID:9431803   PMID:9441664   PMID:9441679   PMID:9466889  
PMID:9486531   PMID:9490412   PMID:9493826   PMID:9500550   PMID:9520484   PMID:9550720   PMID:9550729   PMID:9585504   PMID:9598342   PMID:9636069   PMID:9655799   PMID:9671576  
PMID:9712518   PMID:9731531   PMID:9731532   PMID:9739106   PMID:9739117   PMID:9774514   PMID:9790191   PMID:9799237   PMID:9811571   PMID:9811865   PMID:9825865   PMID:9851841  
PMID:9876179   PMID:9895322   PMID:10049364   PMID:10079226   PMID:10191046   PMID:10208738   PMID:10217145   PMID:10328927   PMID:10349636   PMID:10373301   PMID:10385121   PMID:10421635  
PMID:10423398   PMID:10430909   PMID:10433919   PMID:10452853   PMID:10471502   PMID:10477299   PMID:10479450   PMID:10479457   PMID:10498685   PMID:10499586   PMID:10512182   PMID:10512192  
PMID:10516314   PMID:10518210   PMID:10545241   PMID:10559496   PMID:10600708   PMID:10642791   PMID:10672453   PMID:10688202   PMID:10725236   PMID:10727859   PMID:10772805   PMID:10804177  
PMID:10804184   PMID:10809672   PMID:10818213   PMID:10859308   PMID:10866673   PMID:10887078   PMID:10899756   PMID:10964471   PMID:10985852   PMID:11002334   PMID:11017084   PMID:11027604  
PMID:11042159   PMID:11071781   PMID:11076756   PMID:11076861   PMID:11134352   PMID:11217851   PMID:11290295   PMID:11291865   PMID:11291866   PMID:11298452   PMID:11358868   PMID:11358869  
PMID:11390666   PMID:11418863   PMID:11437453   PMID:11438667   PMID:11449277   PMID:11458389   PMID:11493558   PMID:11566865   PMID:11668679   PMID:11668681   PMID:11688983   PMID:11748146  
PMID:11748151   PMID:11809759   PMID:11820816   PMID:11846474   PMID:11875061   PMID:11884616   PMID:11886853   PMID:11892011   PMID:11900971   PMID:11904435   PMID:11914369   PMID:11934155  
PMID:11934848   PMID:11964482   PMID:11973269   PMID:12015300   PMID:12062060   PMID:12091315   PMID:12117810   PMID:12145169   PMID:12231623   PMID:12351174   PMID:12351178   PMID:12361967  
PMID:12372258   PMID:12372301   PMID:12376107   PMID:12397106   PMID:12421714   PMID:12431380   PMID:12435628   PMID:12435629   PMID:12441287   PMID:12441652   PMID:12447384   PMID:12466851  
PMID:12471260   PMID:12488434   PMID:12490556   PMID:12533514   PMID:12571110   PMID:12588852   PMID:12588859   PMID:12652306   PMID:12774021   PMID:12781686   PMID:12787506   PMID:12812795  
PMID:12835403   PMID:12842913   PMID:12869553   PMID:12952897   PMID:13129926   PMID:14502576   PMID:14504237   PMID:14511481   PMID:14603322   PMID:14645126   PMID:14668413   PMID:14681479  
PMID:14701942   PMID:14736742   PMID:14736744   PMID:14757645   PMID:15005571   PMID:15014077   PMID:15075292   PMID:15084457   PMID:15105370   PMID:15105374   PMID:15136151   PMID:15142971  
PMID:15183723   PMID:15215210   PMID:15218525   PMID:15219627   PMID:15229603   PMID:15231714   PMID:15261829   PMID:15302604   PMID:15314688   PMID:15329346   PMID:15355796   PMID:15371312  
PMID:15389796   PMID:15452354   PMID:15469978   PMID:15485926   PMID:15533813   PMID:15539431   PMID:15567715   PMID:15576401   PMID:15576403   PMID:15576405   PMID:15616563   PMID:15618518  
PMID:15623804   PMID:15668254   PMID:15680365   PMID:15737987   PMID:15739227   PMID:15778864   PMID:15789444   PMID:15804564   PMID:15817462   PMID:15857913   PMID:15899870   PMID:15959514  
PMID:15987773   PMID:15987774   PMID:16001449   PMID:16055718   PMID:16061793   PMID:16098831   PMID:16109169   PMID:16109395   PMID:16141072   PMID:16141073   PMID:16155214   PMID:16207754  
PMID:16210401   PMID:16214823   PMID:16256739   PMID:16284942   PMID:16291788   PMID:16291790   PMID:16357211   PMID:16364283   PMID:16364285   PMID:16368929   PMID:16376864   PMID:16397896  
PMID:16407399   PMID:16414041   PMID:16459298   PMID:16459311   PMID:16467259   PMID:16467360   PMID:16494859   PMID:16537918   PMID:16564040   PMID:16571633   PMID:16602821   PMID:16627590  
PMID:16647304   PMID:16678814   PMID:16728477   PMID:16740652   PMID:16806149   PMID:16831833   PMID:16839541   PMID:16847327   PMID:16887818   PMID:16893423   PMID:16912273   PMID:16912278  
PMID:16943278   PMID:16956603   PMID:17027958   PMID:17035289   PMID:17086203   PMID:17117439   PMID:17210915   PMID:17220277   PMID:17260385   PMID:17304540   PMID:17321515   PMID:17327429  
PMID:17331196   PMID:17389379   PMID:17428829   PMID:17442700   PMID:17478445   PMID:17488627   PMID:17490632   PMID:17504940   PMID:17504941   PMID:17507393   PMID:17507410   PMID:17553904  
PMID:17596284   PMID:17609113   PMID:17611225   PMID:17611227   PMID:17882221   PMID:17908556   PMID:17922007   PMID:17936261   PMID:17936263   PMID:18003640   PMID:18036209   PMID:18061569  
PMID:18076286   PMID:18094027   PMID:18161057   PMID:18171685   PMID:18224709   PMID:18241853   PMID:18268105   PMID:18287559   PMID:18296642   PMID:18324732   PMID:18327258   PMID:18332127  
PMID:18336786   PMID:18339816   PMID:18351630   PMID:18358466   PMID:18374910   PMID:18381283   PMID:18400219   PMID:18403408   PMID:18462699   PMID:18478268   PMID:18497885   PMID:18498097  
PMID:18539113   PMID:18554416   PMID:18556755   PMID:18590716   PMID:18590718   PMID:18611952   PMID:18617531   PMID:18635606   PMID:18660816   PMID:18662545   PMID:18692041   PMID:18697220  
PMID:18701067   PMID:18701545   PMID:18722179   PMID:18773495   PMID:18778483   PMID:18781635   PMID:18787082   PMID:18794365   PMID:18798232   PMID:18820178   PMID:18832392   PMID:18927156  
PMID:18929642   PMID:18930042   PMID:18953410   PMID:18973680   PMID:18974875   PMID:18991257   PMID:19000668   PMID:19004860   PMID:19056886   PMID:19097184   PMID:19103193   PMID:19103755  
PMID:19122665   PMID:19141476   PMID:19168680   PMID:19213785   PMID:19223390   PMID:19234065   PMID:19270025   PMID:19286674   PMID:19298856   PMID:19300477   PMID:19334287   PMID:19339686  
PMID:19369400   PMID:19379695   PMID:19389367   PMID:19390486   PMID:19415718   PMID:19417011   PMID:19436110   PMID:19439492   PMID:19474151   PMID:19487809   PMID:19502415   PMID:19542360  
PMID:19556507   PMID:19562671   PMID:19589781   PMID:19592253   PMID:19592574   PMID:19607821   PMID:19615442   PMID:19628779   PMID:19666503   PMID:19686689   PMID:19720144   PMID:19732765  
PMID:19737349   PMID:19737569   PMID:19767740   PMID:19774071   PMID:19776033   PMID:19786569   PMID:19825428   PMID:19835856   PMID:19850875   PMID:19877275   PMID:19877283   PMID:19896480  
PMID:19951692   PMID:19956259   PMID:20035737   PMID:20040491   PMID:20067783   PMID:20074681   PMID:20108349   PMID:20148032   PMID:20159594   PMID:20175877   PMID:20211162   PMID:20347503  
PMID:20350929   PMID:20450902   PMID:20460368   PMID:20463034   PMID:20483781   PMID:20484741   PMID:20508035   PMID:20516201   PMID:20533405   PMID:20534694   PMID:20551221   PMID:20562861  
PMID:20572855   PMID:20573697   PMID:20609350   PMID:20610763   PMID:20637190   PMID:20678497   PMID:20689803   PMID:20692247   PMID:20708584   PMID:20727874   PMID:20730911   PMID:20842632  
PMID:20849957   PMID:20880840   PMID:20934536   PMID:20960561   PMID:20978075   PMID:21045211   PMID:21057506   PMID:21062862   PMID:21068056   PMID:21093585   PMID:21098568   PMID:21106844  
PMID:21205797   PMID:21209331   PMID:21215373   PMID:21246650   PMID:21267068   PMID:21292830   PMID:21337666   PMID:21445260   PMID:21466802   PMID:21472823   PMID:21552265   PMID:21565611  
PMID:21664576   PMID:21677750   PMID:21682884   PMID:21689430   PMID:21693517   PMID:21704616   PMID:21731673   PMID:21752929   PMID:21761479   PMID:21763481   PMID:21763783   PMID:21775418  
PMID:21786021   PMID:21791528   PMID:21822279   PMID:21829703   PMID:21831921   PMID:21873635   PMID:21896659   PMID:21912524   PMID:21920314   PMID:21924257   PMID:21982711   PMID:22001906  
PMID:22007132   PMID:22040871   PMID:22075149   PMID:22096492   PMID:22103442   PMID:22121118   PMID:22132182   PMID:22179047   PMID:22182519   PMID:22186731   PMID:22265403   PMID:22278924  
PMID:22342906   PMID:22383895   PMID:22529374   PMID:22537018   PMID:22542185   PMID:22549777   PMID:22554696   PMID:22554936   PMID:22573616   PMID:22595668   PMID:22595669   PMID:22607194  
PMID:22669107   PMID:22696295   PMID:22698544   PMID:22737085   PMID:22745311   PMID:22780989   PMID:22841806   PMID:22865702   PMID:22889265   PMID:22902530   PMID:22912414   PMID:22921202  
PMID:22945641   PMID:23006325   PMID:23024056   PMID:23060003   PMID:23071453   PMID:23109420   PMID:23117660   PMID:23154415   PMID:23166838   PMID:23193182   PMID:23201023   PMID:23213408  
PMID:23213461   PMID:23217170   PMID:23260146   PMID:23283079   PMID:23324743   PMID:23332756   PMID:23359409   PMID:23383217   PMID:23416070   PMID:23420609   PMID:23471918   PMID:23471965  
PMID:23482494   PMID:23521771   PMID:23552073   PMID:23618354   PMID:23620511   PMID:23637192   PMID:23651855   PMID:23707899   PMID:23712942   PMID:23729668   PMID:23746980   PMID:23754747  
PMID:23775071   PMID:23822876   PMID:23823474   PMID:23824574   PMID:23884445   PMID:23900540   PMID:23924632   PMID:23955340   PMID:23975021   PMID:23988578   PMID:23993789   PMID:24025729  
PMID:24104551   PMID:24244203   PMID:24302887   PMID:24318810   PMID:24327960   PMID:24348261   PMID:24401371   PMID:24449835   PMID:24496614   PMID:24524909   PMID:24558432   PMID:24596343  
PMID:24613616   PMID:24616493   PMID:24627476   PMID:24633704   PMID:24697898   PMID:24706806   PMID:24797473   PMID:24801048   PMID:24853502   PMID:24859004   PMID:24875183   PMID:24928429  
PMID:24939938   PMID:24948600   PMID:24952961   PMID:24968361   PMID:24970044   PMID:24995796   PMID:25053429   PMID:25056828   PMID:25063451   PMID:25083987   PMID:25091041   PMID:25128525  
PMID:25231759   PMID:25231763   PMID:25249461   PMID:25249938   PMID:25263553   PMID:25294941   PMID:25338007   PMID:25340710   PMID:25343275   PMID:25358791   PMID:25370275   PMID:25371369  
PMID:25392491   PMID:25419850   PMID:25437555   PMID:25446530   PMID:25458012   PMID:25467979   PMID:25480985   PMID:25511461   PMID:25530182   PMID:25569111   PMID:25588837   PMID:25599390  
PMID:25601450   PMID:25631042   PMID:25715394   PMID:25759364   PMID:25760946   PMID:25772331   PMID:25804738   PMID:25834022   PMID:25840610   PMID:25910836   PMID:25912685   PMID:25915474  
PMID:25936505   PMID:25968320   PMID:25977363   PMID:25995356   PMID:26077908   PMID:26164566   PMID:26283356   PMID:26329601   PMID:26354024   PMID:26395490   PMID:26416771   PMID:26440894  
PMID:26444681   PMID:26494787   PMID:26498761   PMID:26512061   PMID:26534985   PMID:26542012   PMID:26551672   PMID:26680304   PMID:26724386   PMID:26771085   PMID:26809587   PMID:26839365  
PMID:26882312   PMID:26884322   PMID:26901059   PMID:26912775   PMID:26929406   PMID:26965371   PMID:27006501   PMID:27019112   PMID:27026076   PMID:27045898   PMID:27061115   PMID:27072135  
PMID:27173853   PMID:27178667   PMID:27188978   PMID:27292645   PMID:27297885   PMID:27320915   PMID:27335464   PMID:27453501   PMID:27466203   PMID:27586544   PMID:27606604   PMID:27633995  
PMID:27639079   PMID:27740873   PMID:27760115   PMID:27789623   PMID:27849569   PMID:27904043   PMID:27930333   PMID:27934886   PMID:27993987   PMID:28049832   PMID:28087629   PMID:28174238  
PMID:28174244   PMID:28182636   PMID:28188614   PMID:28193997   PMID:28195173   PMID:28235042   PMID:28263766   PMID:28264835   PMID:28291807   PMID:28322735   PMID:28346423   PMID:28346476  
PMID:28371069   PMID:28379358   PMID:28412462   PMID:28501476   PMID:28501478   PMID:28506991   PMID:28530676   PMID:28576773   PMID:28580283   PMID:28619992   PMID:28673820   PMID:28688895  
PMID:28800946   PMID:28817564   PMID:28839193   PMID:28854362   PMID:28891097   PMID:28926609   PMID:28939119   PMID:28948682   PMID:28973288   PMID:29037931   PMID:29038301   PMID:29056338  
PMID:29068314   PMID:29138513   PMID:29203676   PMID:29222391   PMID:29389974   PMID:29412136   PMID:29463648   PMID:29484800   PMID:29487109   PMID:29559661   PMID:29571613   PMID:29648668  
PMID:29659575   PMID:29725084   PMID:29915126   PMID:29934619   PMID:29964027   PMID:29981427   PMID:30061015   PMID:30093553   PMID:30189017   PMID:30232173   PMID:30256791   PMID:30301781  
PMID:30318151   PMID:30380057   PMID:30452456   PMID:30472119   PMID:30475207   PMID:30487608   PMID:30559277   PMID:30576223   PMID:30661738   PMID:30674481   PMID:30692221   PMID:30791390  
PMID:30814516   PMID:30872278   PMID:30872480   PMID:30923168   PMID:30940539   PMID:30959515   PMID:31006510   PMID:31175693   PMID:31235634   PMID:31291587   PMID:31308417   PMID:31350899  
PMID:31371375   PMID:31371508   PMID:31427537   PMID:31461644   PMID:31607856   PMID:31634536   PMID:31670387   PMID:31689237   PMID:31750563   PMID:31772170   PMID:31776260   PMID:31789450  
PMID:31881038   PMID:31887266   PMID:31950080   PMID:31964774   PMID:31988094   PMID:32143325   PMID:32156757   PMID:32179481   PMID:32375051   PMID:32392211   PMID:32439762   PMID:32450229  
PMID:32467237   PMID:32561546   PMID:32597756   PMID:32628936   PMID:32645357   PMID:32702291   PMID:32758357   PMID:32855417   PMID:32900950   PMID:33048843   PMID:33051257   PMID:33103996  
PMID:33144666   PMID:33199445   PMID:33398177   PMID:33571746   PMID:33636105   PMID:33810480   PMID:33951080   PMID:33999917   PMID:34009125   PMID:34104947   PMID:34168324   PMID:34215813  
PMID:34246806   PMID:34321664   PMID:34323272   PMID:34346313   PMID:34433966   PMID:34478646   PMID:34486668   PMID:34547143   PMID:34575858   PMID:34599818   PMID:34671097   PMID:34672258  
PMID:34686322   PMID:34752747   PMID:34769078   PMID:35017475   PMID:35194044   PMID:35294885   PMID:35383354   PMID:35398294   PMID:35440748   PMID:35444014   PMID:35681011   PMID:35686629  
PMID:35700056   PMID:35703180   PMID:35779606   PMID:35831953   PMID:35835117   PMID:35858415   PMID:35861728   PMID:35866844   PMID:35876795   PMID:35927244   PMID:35950911   PMID:35988542  
PMID:36003391   PMID:36007540   PMID:36026468   PMID:36046192   PMID:36123357   PMID:36130202   PMID:36282544   PMID:36318802   PMID:36332622   PMID:36395107   PMID:36398878   PMID:36516856  
PMID:36517595   PMID:36522168   PMID:36595695   PMID:36611017   PMID:36624844   PMID:36644009   PMID:36669111   PMID:36917198   PMID:36941669   PMID:37080203   PMID:37228654   PMID:37296573  
PMID:37315133   PMID:37390294   PMID:37414952   PMID:37528140   PMID:37633271   PMID:37752418   PMID:37756583   PMID:37879405   PMID:37943875   PMID:37944068   PMID:38084145   PMID:38110169  
PMID:38135007   PMID:38171360   PMID:38191655  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392147,884,797 - 147,888,889 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2147,884,797 - 147,888,889 (-)EnsemblGRCm39 Ensembl
GRCm382148,042,877 - 148,046,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,042,877 - 148,046,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv372147,868,614 - 147,872,705 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362147,734,364 - 147,738,410 (-)NCBIMGSCv36mm8
Celera2149,306,403 - 149,310,523 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.38NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382022,580,998 - 22,585,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2022,580,998 - 22,585,455 (-)EnsemblGRCh38hg38GRCh38
GRCh372022,561,636 - 22,566,128 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362022,509,823 - 22,514,102 (-)NCBINCBI36Build 36hg18NCBI36
Celera2022,635,086 - 22,639,544 (-)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2022,523,682 - 22,527,950 (-)NCBIHuRef
CHM1_12022,562,253 - 22,566,723 (-)NCBICHM1_1
T2T-CHM13v2.02022,640,367 - 22,644,859 (-)NCBIT2T-CHM13v2.0
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
GRCr83155,923,305 - 155,927,508 (-)NCBIGRCr8
mRatBN7.23135,470,123 - 135,474,326 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3135,470,131 - 135,474,326 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3139,406,140 - 139,410,336 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03147,990,259 - 147,994,455 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03145,698,089 - 145,702,294 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03142,383,084 - 142,387,493 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3142,383,278 - 142,387,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03148,793,310 - 148,797,690 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43136,739,009 - 136,743,204 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13136,644,581 - 136,648,777 (-)NCBI
Celera3134,324,023 - 134,328,218 (-)NCBICelera
Cytogenetic Map3q41NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495541529,982,940 - 29,986,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541529,982,940 - 29,987,093 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan1-v22123,451,059 - 23,454,654 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12023,447,894 - 23,451,489 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02022,519,942 - 22,524,262 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12022,872,251 - 22,874,997 (-)NCBIpanpan1.1PanPan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1241,010,370 - 1,013,791 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl241,010,651 - 1,013,072 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha241,034,459 - 1,038,788 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0241,413,104 - 1,417,432 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl241,414,234 - 1,417,447 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1241,010,961 - 1,015,301 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0241,114,770 - 1,118,263 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,388,439 - 1,392,767 (+)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024408640149,544,748 - 149,549,068 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366202,966,341 - 2,969,349 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366202,966,341 - 2,969,349 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1729,997,401 - 30,001,707 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11729,997,397 - 30,001,704 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,053,453 - 34,057,746 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1251,577,127 - 51,585,168 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl251,577,833 - 51,580,297 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660786,377,377 - 6,381,582 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_00462474122,645,519 - 22,649,854 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474122,645,580 - 22,649,722 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Foxa2
156 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:674
Count of miRNA genes:397
Interacting mature miRNAs:424
Transcripts:ENSMUST00000047315, ENSMUST00000109964, ENSMUST00000146242, ENSMUST00000172928
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
4141033Wg2d_mweight gain in high growth mice 2d (mouse)Not determined143773445160303008Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
13504830Bacsq1_mbaculum shape QTL 1 (mouse)2145716184161016184Mouse

Markers in Region
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,042,907 - 148,043,010UniSTSGRCm38
MGSCv372147,868,643 - 147,868,746UniSTSGRCm37
Celera2149,306,432 - 149,306,535UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,043,190 - 148,043,389UniSTSGRCm38
MGSCv372147,868,926 - 147,869,125UniSTSGRCm37
Celera2149,306,715 - 149,306,914UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Whitehead_YAC2 UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,044,185 - 148,044,472UniSTSGRCm38
MGSCv372147,869,921 - 147,870,208UniSTSGRCm37
Celera2149,307,710 - 149,307,997UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,044,180 - 148,044,382UniSTSGRCm38
MGSCv372147,869,916 - 147,870,118UniSTSGRCm37
Celera2149,307,705 - 149,307,907UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381257,541,406 - 57,541,504UniSTSGRCm38
MGSCv371258,642,393 - 58,642,491UniSTSGRCm37
Celera1258,722,211 - 58,722,309UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic Map12C1UniSTS
cM Map284.0UniSTS
cM Map1226.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,043,769 - 148,043,936UniSTSGRCm38
MGSCv372147,869,505 - 147,869,672UniSTSGRCm37
Celera2149,307,294 - 149,307,461UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,043,037 - 148,043,689UniSTSGRCm38
MGSCv372147,868,773 - 147,869,425UniSTSGRCm37
Celera2149,306,562 - 149,307,214UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,043,039 - 148,043,289UniSTSGRCm38
MGSCv372147,868,775 - 147,869,025UniSTSGRCm37
Celera2149,306,564 - 149,306,814UniSTS
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2G3UniSTS
cM Map284.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382148,043,355 - 148,043,451UniSTSGRCm38
MGSCv372147,869,091 - 147,869,187UniSTSGRCm37
Celera2149,306,880 - 149,306,976UniSTS
Cytogenetic Map2G3UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2G3UniSTS



Nucleotide Sequences
RefSeq Transcripts NM_001291065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB231453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF191558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY902316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU055166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF948812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK023291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L10409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L25669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X76685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000047315   ⟹   ENSMUSP00000045918
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2147,884,797 - 147,888,889 (-)Ensembl
GRCm38.p6 Ensembl2148,042,877 - 148,046,969 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109964   ⟹   ENSMUSP00000105590
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2147,884,797 - 147,887,868 (-)Ensembl
GRCm38.p6 Ensembl2148,042,877 - 148,045,948 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146242
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2147,886,160 - 147,887,384 (-)Ensembl
GRCm38.p6 Ensembl2148,044,240 - 148,045,464 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172928   ⟹   ENSMUSP00000134081
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2147,885,462 - 147,888,816 (-)Ensembl
GRCm38.p6 Ensembl2148,043,542 - 148,046,896 (-)Ensembl
RefSeq Acc Id: NM_001291065   ⟹   NP_001277994
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm392147,884,797 - 147,887,868 (-)NCBI
GRCm382148,042,877 - 148,045,948 (-)NCBI
Celera2149,306,402 - 149,310,523 (-)NCBI
RefSeq Acc Id: NM_001291067   ⟹   NP_001277996
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm392147,884,797 - 147,887,384 (-)NCBI
GRCm382148,042,877 - 148,045,464 (-)NCBI
Celera2149,306,402 - 149,310,523 (-)NCBI
RefSeq Acc Id: NM_010446   ⟹   NP_034576
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm392147,884,797 - 147,888,889 (-)NCBI
GRCm382148,042,877 - 148,046,969 (-)NCBI
MGSCv372147,868,614 - 147,872,705 (-)RGD
Celera2149,306,402 - 149,310,523 (-)NCBI
RefSeq Acc Id: NP_034576   ⟸   NM_010446
- Peptide Label: isoform b
- UniProtKB: A2AR89 (UniProtKB/Swiss-Prot),   Q60602 (UniProtKB/Swiss-Prot),   P35583 (UniProtKB/Swiss-Prot),   Q2M4J9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277996   ⟸   NM_001291067
- Peptide Label: isoform c
- UniProtKB: Q2M4J9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277994   ⟸   NM_001291065
- Peptide Label: isoform a
- UniProtKB: G5E8P5 (UniProtKB/TrEMBL),   Q2M4J9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000134081   ⟸   ENSMUST00000172928
RefSeq Acc Id: ENSMUSP00000045918   ⟸   ENSMUST00000047315
RefSeq Acc Id: ENSMUSP00000105590   ⟸   ENSMUST00000109964
Protein Domains

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35583-F1-model_v2 AlphaFold P35583 1-459 view protein structure

RGD ID:6831399
Promoter ID:MM_KWN:32133
SO ACC ID:SO:0000170
Tissues & Cell Lines:ES_Cell,   Liver,   Lung
Transcripts:ENSMUST00000109964,   OTTMUST00000037261
Mouse AssemblyChrPosition (strand)Source
MGSCv362147,871,436 - 147,872,397 (-)MPROMDB
RGD ID:6831394
Promoter ID:MM_KWN:32134
SO ACC ID:SO:0000170
Tissues & Cell Lines:Liver,   Lung
Mouse AssemblyChrPosition (strand)Source
MGSCv362147,872,416 - 147,872,916 (-)MPROMDB
RGD ID:6879060
Promoter ID:EPDNEW_M2972
Type:single initiation site
Description:Mus musculus forkhead box A2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Alternative Promoters:null; see alsoEPDNEW_M2973  EPDNEW_M2974  
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm382148,045,898 - 148,045,958EPDNEW
RGD ID:6879044
Promoter ID:EPDNEW_M2973
Type:single initiation site
Description:Mus musculus forkhead box A2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Alternative Promoters:null; see alsoEPDNEW_M2974  EPDNEW_M2972  
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm382148,046,340 - 148,046,400EPDNEW
RGD ID:6879046
Promoter ID:EPDNEW_M2974
Type:multiple initiation site
Description:Mus musculus forkhead box A2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Alternative Promoters:null; see alsoEPDNEW_M2973  EPDNEW_M2972  
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm382148,047,062 - 148,047,122EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1347476 AgrOrtholog
Ensembl Genes ENSMUSG00000037025 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047315 ENTREZGENE
  ENSMUST00000047315.10 UniProtKB/Swiss-Prot
  ENSMUST00000109964.8 UniProtKB/TrEMBL
  ENSMUST00000172928.2 UniProtKB/TrEMBL
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Fork-head_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Forkhead_box_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15376 UniProtKB/Swiss-Prot
Pfam Forkhead UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Forkhead_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HNF_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Foxa2 PhenoGen
  FORK_HEAD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00339 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FOXA2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A2AR89 UniProtKB/Swiss-Prot
  Q60602 UniProtKB/Swiss-Prot